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The map label for this gene is kdsC [H]

Identifier: 209694097

GI number: 209694097

Start: 560809

End: 561366

Strand: Reverse

Name: kdsC [H]

Synonym: VSAL_I0502

Alternate gene names: 209694097

Gene position: 561366-560809 (Counterclockwise)

Preceding gene: 209694098

Following gene: 209694096

Centisome position: 16.88

GC content: 40.5

Gene sequence:

>558_bases
ATGCCAACCATGATCGAAACCCTTTATGGTGAAGTGGAAGAATCAATCCTCTCTATCGCTAAAACAATAAAACTGCTCAT
TTGTGATGTTGATGGTGTCTTTTCTGACGGCCTTGTTTATATGGGCAATGACGGTGAAGAATTAAAAACCTTTCATACTC
GCGATGGGTATGGTGTTAAATCATTAATGTCTGCGGGTGTTGAAGTTGCAATTATTACAGGACGCAACTCTCAAATTGTA
GAAAATAGAATGAGAGCACTTGGTATTTCACTTATCTACCAAGGCCAAGACAATAAATTACAAGCATATGAAGATATTTT
AACTAAACTCAACATAGCACCTGAACATACGGGTTACATCGGTGATGATCTGATCGATTGGCCTGTAATGGAAAAGGTGG
CACTTAAAGTCTGCGTTGCCGATGGTCATCCCCTACTGGTTAAACGTGCAAACTATGTGACCACCATTAAAGGCGGTCAC
GGTGCGGTTCGTGAAGTAAGCGACCTTATCTTGGAAGCAAAAGGGGAATTAGAGCAACATAAAGGCTTAAGTATATGA

Upstream 100 bases:

>100_bases
TGCAAGATAAAAAAATTAATGGCTTATTGCTATGCGATGAAAACAATCGCTTAGTCGGCGCATTGAATATGCATGATCTT
CTAAAAGCAGGAGTAATGTA

Downstream 100 bases:

>100_bases
CCCTAAAACACCTTTTTATGACCTTATTGTTATTGATCGCAAGTTGGTCAGGCTATTACTTGTATTATGAATACGCAAAA
AGCGAACAACAAGTAATCCC

Product: 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 185; Mature: 184

Protein sequence:

>185_residues
MPTMIETLYGEVEESILSIAKTIKLLICDVDGVFSDGLVYMGNDGEELKTFHTRDGYGVKSLMSAGVEVAIITGRNSQIV
ENRMRALGISLIYQGQDNKLQAYEDILTKLNIAPEHTGYIGDDLIDWPVMEKVALKVCVADGHPLLVKRANYVTTIKGGH
GAVREVSDLILEAKGELEQHKGLSI

Sequences:

>Translated_185_residues
MPTMIETLYGEVEESILSIAKTIKLLICDVDGVFSDGLVYMGNDGEELKTFHTRDGYGVKSLMSAGVEVAIITGRNSQIV
ENRMRALGISLIYQGQDNKLQAYEDILTKLNIAPEHTGYIGDDLIDWPVMEKVALKVCVADGHPLLVKRANYVTTIKGGH
GAVREVSDLILEAKGELEQHKGLSI
>Mature_184_residues
PTMIETLYGEVEESILSIAKTIKLLICDVDGVFSDGLVYMGNDGEELKTFHTRDGYGVKSLMSAGVEVAIITGRNSQIVE
NRMRALGISLIYQGQDNKLQAYEDILTKLNIAPEHTGYIGDDLIDWPVMEKVALKVCVADGHPLLVKRANYVTTIKGGHG
AVREVSDLILEAKGELEQHKGLSI

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=152, Percent_Identity=25.6578947368421, Blast_Score=72, Evalue=4e-13,
Organism=Escherichia coli, GI2367202, Length=181, Percent_Identity=60.7734806629834, Blast_Score=235, Evalue=1e-63,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 20261; Mature: 20129

Theoretical pI: Translated: 4.77; Mature: 4.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPTMIETLYGEVEESILSIAKTIKLLICDVDGVFSDGLVYMGNDGEELKTFHTRDGYGVK
CCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEECCCCHHHHEEECCCCCCHH
SLMSAGVEVAIITGRNSQIVENRMRALGISLIYQGQDNKLQAYEDILTKLNIAPEHTGYI
HHHHCCCEEEEEECCCHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
GDDLIDWPVMEKVALKVCVADGHPLLVKRANYVTTIKGGHGAVREVSDLILEAKGELEQH
CCCHHCCHHHHHHHHHHEECCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHCCCCHHHC
KGLSI
CCCCC
>Mature Secondary Structure 
PTMIETLYGEVEESILSIAKTIKLLICDVDGVFSDGLVYMGNDGEELKTFHTRDGYGVK
CHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCEEEECCCCHHHHEEECCCCCCHH
SLMSAGVEVAIITGRNSQIVENRMRALGISLIYQGQDNKLQAYEDILTKLNIAPEHTGYI
HHHHCCCEEEEEECCCHHHHHHHHHHHCEEEEEECCCCCHHHHHHHHHHCCCCCCCCCCC
GDDLIDWPVMEKVALKVCVADGHPLLVKRANYVTTIKGGHGAVREVSDLILEAKGELEQH
CCCHHCCHHHHHHHHHHEECCCCEEEEEECCEEEEEECCCCHHHHHHHHHHHCCCCHHHC
KGLSI
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]