Click here to switch to the map view.

The map label for this gene is fkpB [C]

Identifier: 197119920

GI number: 197119920

Start: 4073302

End: 4073754

Strand: Direct

Name: fkpB [C]

Synonym: Gbem_3559

Alternate gene names: 197119920

Gene position: 4073302-4073754 (Clockwise)

Preceding gene: 197119916

Following gene: 197119922

Centisome position: 88.26

GC content: 58.06

Gene sequence:

>453_bases
ATGGCACAGGCTAAAGAAGGGGATCGCGTAAAGGTCCATTATACGGGGAAGCTCGATGACGGTTCCATTTTCGATTCTTC
GGAATGCGCTGAGGACGATTGCGGCTGCGGGCCTGGCCCGATCGAGTTCACCATTGGACAGGGAGAAGTCATTCCTGGCT
TCGAGGCAGGGATAAAAGGTCTTTCGGTCGGTGAAAGCAAGACCATCCATATCCCGGTCGAGGAAGCCTACGGCGAGAGG
GTCCAGGAGATGGTTGCGGTAGTACCCCGCGGCGATCTGCCTCCCGAAATGAACCCTGAGGTCGGGCAGCAGCTCGAAGT
GACCCAGGAAGACGGCCAGGTGTTCAGCGTACTGGTGGTCGAGGTGACCAACGAAACCATCACCATCGACGCCAACCACC
CGCTGGCCGGCCAGCCGCTCAACTTCGAACTGAAGCTGGTAGAGATCCTCTAG

Upstream 100 bases:

>100_bases
GGGAGATCCCCGACATTATCCGCAAATTTAGTGTGGATAATTGCCCGACTGTCTGTTATCGTTCAGCACTTGTTTTCCAA
AATAATCAAGAGGTGGCGTT

Downstream 100 bases:

>100_bases
CGGCAGGCTTTCACGGCAGACAAAAAAATCCCCTCCCCGGCAACGAGGAGGGGATTTTTTCATCCCTTAAGCCAAAGCGC
GCTTGGCGCTTTTAGTTTTC

Product: FKBP-type peptidylprolyl cis-trans isomerase

Products: NA

Alternate protein names: PPIase; MtFK; Rotamase [H]

Number of amino acids: Translated: 150; Mature: 149

Protein sequence:

>150_residues
MAQAKEGDRVKVHYTGKLDDGSIFDSSECAEDDCGCGPGPIEFTIGQGEVIPGFEAGIKGLSVGESKTIHIPVEEAYGER
VQEMVAVVPRGDLPPEMNPEVGQQLEVTQEDGQVFSVLVVEVTNETITIDANHPLAGQPLNFELKLVEIL

Sequences:

>Translated_150_residues
MAQAKEGDRVKVHYTGKLDDGSIFDSSECAEDDCGCGPGPIEFTIGQGEVIPGFEAGIKGLSVGESKTIHIPVEEAYGER
VQEMVAVVPRGDLPPEMNPEVGQQLEVTQEDGQVFSVLVVEVTNETITIDANHPLAGQPLNFELKLVEIL
>Mature_149_residues
AQAKEGDRVKVHYTGKLDDGSIFDSSECAEDDCGCGPGPIEFTIGQGEVIPGFEAGIKGLSVGESKTIHIPVEEAYGERV
QEMVAVVPRGDLPPEMNPEVGQQLEVTQEDGQVFSVLVVEVTNETITIDANHPLAGQPLNFELKLVEIL

Specific function: PPIases accelerate the folding of proteins [H]

COG id: COG1047

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 2

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Homo sapiens, GI206725530, Length=78, Percent_Identity=41.025641025641, Blast_Score=64, Evalue=4e-11,
Organism=Homo sapiens, GI17149844, Length=78, Percent_Identity=41.025641025641, Blast_Score=64, Evalue=4e-11,
Organism=Homo sapiens, GI17149842, Length=78, Percent_Identity=41.025641025641, Blast_Score=64, Evalue=4e-11,
Organism=Escherichia coli, GI1786211, Length=140, Percent_Identity=32.1428571428571, Blast_Score=75, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17540882, Length=78, Percent_Identity=39.7435897435897, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6320727, Length=81, Percent_Identity=44.4444444444444, Blast_Score=69, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323566, Length=78, Percent_Identity=41.025641025641, Blast_Score=65, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6323482, Length=79, Percent_Identity=39.2405063291139, Blast_Score=62, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24655568, Length=76, Percent_Identity=46.0526315789474, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179 [H]

Pfam domain/function: PF00254 FKBP_C [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 16091; Mature: 15960

Theoretical pI: Translated: 3.93; Mature: 3.93

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQAKEGDRVKVHYTGKLDDGSIFDSSECAEDDCGCGPGPIEFTIGQGEVIPGFEAGIKG
CCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHCCCE
LSVGESKTIHIPVEEAYGERVQEMVAVVPRGDLPPEMNPEVGQQLEVTQEDGQVFSVLVV
EECCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEE
EVTNETITIDANHPLAGQPLNFELKLVEIL
EECCCEEEEECCCCCCCCCCCEEEEEEEEC
>Mature Secondary Structure 
AQAKEGDRVKVHYTGKLDDGSIFDSSECAEDDCGCGPGPIEFTIGQGEVIPGFEAGIKG
CCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCHHHCCCE
LSVGESKTIHIPVEEAYGERVQEMVAVVPRGDLPPEMNPEVGQQLEVTQEDGQVFSVLVV
EECCCCCEEEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEECCCCCEEEEEEE
EVTNETITIDANHPLAGQPLNFELKLVEIL
EECCCEEEEECCCCCCCCCCCEEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9440528 [H]