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The map label for this gene is kynB [H]

Identifier: 197119916

GI number: 197119916

Start: 4070216

End: 4070896

Strand: Direct

Name: kynB [H]

Synonym: Gbem_3555

Alternate gene names: 197119916

Gene position: 4070216-4070896 (Clockwise)

Preceding gene: 197119915

Following gene: 197119920

Centisome position: 88.19

GC content: 61.23

Gene sequence:

>681_bases
ATGCGAATCCACGACATTACCGTTTCCCTCTCCAGCGATCTTCCCATCTACCCAGGCGACCCCGGCATCACCATCGAACC
CTTCAGCCGCATCTCCCAAGGCGATTCCGCCAACGTCTCCCGCATCAGCATGGGAAGCCACAGCGGCACCCATCTCGACG
CGCCGTTCCATTTCGACGACGCCGGAACCACGGTCGACGAGATCGCACTGGAAACCGTGATCGGCAAGGCGCTGGTGCTG
GAGATCCTCGGCACCAAGGAAATCGGGCGTCAGGAACTGGAGAAGTTTCGCATCGAGGGGGAAGAGCGGCTGCTGCTGAA
GACGGACAACTCGAAGCTCTGGCAGCAAAAGGGATTTTCCGAAGAGTACGCCGCCCTCACCAAAGACGGCGCGCAGTACC
TGCGGGACGCAGGGGTGAGGCTCGTAGGGATAGACTATCTCTCCATCGAAGGGTTCCATGGCGAGGGGGACGTACACCGC
ACCTTGCTGGAAGACGGCATACTGGTAATCGAGGGGTTGAACCTGGAAGGCATCAAGGCGGGGCACTACCAGCTCATCTG
TCTGCCGCTGAAGCTTAAAGGCGGGGACGGAGCGCCCGTGCGGGCGCTCCTGATTGGCGGTTCCGATTCCGCTACCGAGC
CGGAGTTCGATCCCCACACCAGCAAATGGCCGCTGGCGTGA

Upstream 100 bases:

>100_bases
TTATAATTTGCCGGCTGCATAATCAGCAGGTCTTTCCATTGTCAATTGTCCATTGTCAATTGTCCATTGTCAATCGTCAA
TTGGTTAGACGGAGGTACCG

Downstream 100 bases:

>100_bases
AACCCGGCTATAGCGGCTGATACTTCTTGTCTTTGTTGCAGCACGGCTTCTGCACCGGCTGCTCAGCCGGCTGCTTCAGT
TTCGCGCATTTGTCGCATCC

Product: cyclase/hydrolase

Products: NA

Alternate protein names: KFA; N-formylkynurenine formamidase [H]

Number of amino acids: Translated: 226; Mature: 226

Protein sequence:

>226_residues
MRIHDITVSLSSDLPIYPGDPGITIEPFSRISQGDSANVSRISMGSHSGTHLDAPFHFDDAGTTVDEIALETVIGKALVL
EILGTKEIGRQELEKFRIEGEERLLLKTDNSKLWQQKGFSEEYAALTKDGAQYLRDAGVRLVGIDYLSIEGFHGEGDVHR
TLLEDGILVIEGLNLEGIKAGHYQLICLPLKLKGGDGAPVRALLIGGSDSATEPEFDPHTSKWPLA

Sequences:

>Translated_226_residues
MRIHDITVSLSSDLPIYPGDPGITIEPFSRISQGDSANVSRISMGSHSGTHLDAPFHFDDAGTTVDEIALETVIGKALVL
EILGTKEIGRQELEKFRIEGEERLLLKTDNSKLWQQKGFSEEYAALTKDGAQYLRDAGVRLVGIDYLSIEGFHGEGDVHR
TLLEDGILVIEGLNLEGIKAGHYQLICLPLKLKGGDGAPVRALLIGGSDSATEPEFDPHTSKWPLA
>Mature_226_residues
MRIHDITVSLSSDLPIYPGDPGITIEPFSRISQGDSANVSRISMGSHSGTHLDAPFHFDDAGTTVDEIALETVIGKALVL
EILGTKEIGRQELEKFRIEGEERLLLKTDNSKLWQQKGFSEEYAALTKDGAQYLRDAGVRLVGIDYLSIEGFHGEGDVHR
TLLEDGILVIEGLNLEGIKAGHYQLICLPLKLKGGDGAPVRALLIGGSDSATEPEFDPHTSKWPLA

Specific function: Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine [H]

COG id: COG1878

COG function: function code R; Predicted metal-dependent hydrolase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kynB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017484
- InterPro:   IPR007325 [H]

Pfam domain/function: PF04199 Cyclase [H]

EC number: =3.5.1.9 [H]

Molecular weight: Translated: 24558; Mature: 24558

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIHDITVSLSSDLPIYPGDPGITIEPFSRISQGDSANVSRISMGSHSGTHLDAPFHFDD
CEEEEEEEEECCCCCCCCCCCCCEECCHHHCCCCCCCCEEEEEECCCCCCEECCCEEECC
AGTTVDEIALETVIGKALVLEILGTKEIGRQELEKFRIEGEERLLLKTDNSKLWQQKGFS
CCCHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHCCCCEEEEEEECCCHHHHHCCCC
EEYAALTKDGAQYLRDAGVRLVGIDYLSIEGFHGEGDVHRTLLEDGILVIEGLNLEGIKA
HHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHCCEEEEECCCCCCEEC
GHYQLICLPLKLKGGDGAPVRALLIGGSDSATEPEFDPHTSKWPLA
CCEEEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRIHDITVSLSSDLPIYPGDPGITIEPFSRISQGDSANVSRISMGSHSGTHLDAPFHFDD
CEEEEEEEEECCCCCCCCCCCCCEECCHHHCCCCCCCCEEEEEECCCCCCEECCCEEECC
AGTTVDEIALETVIGKALVLEILGTKEIGRQELEKFRIEGEERLLLKTDNSKLWQQKGFS
CCCHHHHHHHHHHHHHHHHHHHHCCHHCCHHHHHHHHCCCCEEEEEEECCCHHHHHCCCC
EEYAALTKDGAQYLRDAGVRLVGIDYLSIEGFHGEGDVHRTLLEDGILVIEGLNLEGIKA
HHHHHHHHHHHHHHHHCCCEEEEEEEEEEECCCCCCHHHHHHHHCCEEEEECCCCCCEEC
GHYQLICLPLKLKGGDGAPVRALLIGGSDSATEPEFDPHTSKWPLA
CCEEEEEEEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA