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The map label for this gene is mcp022 [H]

Identifier: 197119662

GI number: 197119662

Start: 3790536

End: 3792182

Strand: Direct

Name: mcp022 [H]

Synonym: Gbem_3297

Alternate gene names: 197119662

Gene position: 3790536-3792182 (Clockwise)

Preceding gene: 197119661

Following gene: 197119663

Centisome position: 82.13

GC content: 55.98

Gene sequence:

>1647_bases
ATGAAGTGGTTCATGAACATGAAGATAAAGACAAAAATGGGCCTTGGGTTCACAATCGTCCTCGCCCTTTTCACCTGCGC
GATAGCGGTGACGTGCTTCAACATGGAGCAGGCGAGGAAAGATTCCGAACAGGTTGCCAGCGAATCTGTCCCTTTCCTCA
TGCGCGCATACGACATGAATATCGCCGCAATAAAGTTATCGGAAACCCTTACGGATGTTGCCGCGACCCATAACAACGAA
GGGTTCAAGGAAGCCGAACTGGCGGCGGTGAGGTTCCGGCAAGAACTGGCAAAGTACAGGGAAATGTACATGAGAGAGAA
CGACGAAAAATCTCTCCGAGAAATGGACGAGCTGGGGAAAAGCTTCGACAAGTTCTACGACACAGGTAAAAAGATGGCTC
TCACCTATGTCTCATCGGGCCTGGTGCAGGGCAATACGATGATGGACGGTTTTGACAAAGATCGCGCGCTCCTCTCGGCG
GAAATCGAAAAGCTGCAAAAATCCCAGTCAGACGAAGCCAAGGCGAACACAAAGGGGATTGTCACGACACTTAACAAAGT
TTTTCTATTGCTCGTCGCAGCGTGCGGGGTAGCGATCACCTTGGGGATTCTGATTGCCGTCTTCGTAACCCGCAGCATAA
CAGTTCCGCTCCAGAGTGCTGTAGAGGTCTCCAACAAGCTGGCGGAGGGGGACCTGACTGTCGTTGTAACGTCTGAGAAT
ACTGACGAAACTGGCCATCTTTTGGCTGCCATGGGGAACATGGTCTACAAGCTGAGGGAGATCGTGGGAGAGGTGCAGGC
CGCGACCAAGAACGTAGCGTCGGGAAGTCAGGAGCTCTCCTCCAGTTCCGAGCAGATGTCGCAGGGTGCCAGCGAGCAGG
CAGCGGCGGCTGAAGAAGCTTCCGCCAGCATGGAGCAGATGACCTCCAACATCCGTCAGAACGCGGACAACGCGTTGCAG
ACCGAGAAGATAGCAGTCAAGTCCGCGGAAAACGCCAAAGAAGGGGGGCAGGCTGTCCAGGAAACGGTGCACGCGATGAA
GGACATCGCCGGAAAGATCAACATCATCGAGGAAATCGCGCGTCAGACGAACCTTTTAGCCCTGAACGCCGCCATAGAGG
CGGCCCGGGCCGGCGAGCACGGCAAGGGTTTCGCCGTCGTCGCCAGCGAGGTGAGAAAGCTCGCCGAGCGGAGCCAGAAG
GCTGCCGCCGAGATCTCGCAGCTTTCCAGTACCAGCGTCGATGTCGCGGTAAAGGCCGGCGACCTCCTGTCCAAGATGGT
GCCCGACATCCAGAAGACGGCCGAACTGGTCCAGGAGATCAGCGCCTCCAGCAGGGAGCAGGACACCGGGGCGGAGCAGA
TCAACAAGGCGATCCAGCAACTCGACACAGTCATCCAACAAAACGCCGGCGCTTCCGAGGAGATGTCCTCGACAGCAGAG
GAACTTGCTTCGCAGGCGGAACTGCTGACAAGCTCCATCGCCTTCTTCAATATCGGTGAAGAAGGAAGGTCGAAGCCCCT
GGTAAGACATTCCAAGACGACGATGAAGCCGATGAGCTTTAGCAAGCACCCCGCAAAAAGCGCACCTATCGCCAACGTCG
CGGGCACGGATCTCCAATTGAACGACGACCATTTCGAGCACTTCTAA

Upstream 100 bases:

>100_bases
GTTAAACAGCCTGGAGGCGGCTGTTGAGTCCTGTAGCTAGAATTTCCTCAACCACCCCCACCTGCAGAGGTCATCGAGAT
TTGGAAAAGGGAGGCAATTA

Downstream 100 bases:

>100_bases
CGGCACCTGCTTCTGAATGGCAAAAGCCGGGTTCCGCCCTGCGACCGCACGGTCCGACGAAACCCGGCTTTTTTGTTTCC
GACCTTCGATCTAGTTGATC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-III; Ribose and galactose chemoreceptor protein [H]

Number of amino acids: Translated: 548; Mature: 548

Protein sequence:

>548_residues
MKWFMNMKIKTKMGLGFTIVLALFTCAIAVTCFNMEQARKDSEQVASESVPFLMRAYDMNIAAIKLSETLTDVAATHNNE
GFKEAELAAVRFRQELAKYREMYMRENDEKSLREMDELGKSFDKFYDTGKKMALTYVSSGLVQGNTMMDGFDKDRALLSA
EIEKLQKSQSDEAKANTKGIVTTLNKVFLLLVAACGVAITLGILIAVFVTRSITVPLQSAVEVSNKLAEGDLTVVVTSEN
TDETGHLLAAMGNMVYKLREIVGEVQAATKNVASGSQELSSSSEQMSQGASEQAAAAEEASASMEQMTSNIRQNADNALQ
TEKIAVKSAENAKEGGQAVQETVHAMKDIAGKINIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAERSQK
AAAEISQLSSTSVDVAVKAGDLLSKMVPDIQKTAELVQEISASSREQDTGAEQINKAIQQLDTVIQQNAGASEEMSSTAE
ELASQAELLTSSIAFFNIGEEGRSKPLVRHSKTTMKPMSFSKHPAKSAPIANVAGTDLQLNDDHFEHF

Sequences:

>Translated_548_residues
MKWFMNMKIKTKMGLGFTIVLALFTCAIAVTCFNMEQARKDSEQVASESVPFLMRAYDMNIAAIKLSETLTDVAATHNNE
GFKEAELAAVRFRQELAKYREMYMRENDEKSLREMDELGKSFDKFYDTGKKMALTYVSSGLVQGNTMMDGFDKDRALLSA
EIEKLQKSQSDEAKANTKGIVTTLNKVFLLLVAACGVAITLGILIAVFVTRSITVPLQSAVEVSNKLAEGDLTVVVTSEN
TDETGHLLAAMGNMVYKLREIVGEVQAATKNVASGSQELSSSSEQMSQGASEQAAAAEEASASMEQMTSNIRQNADNALQ
TEKIAVKSAENAKEGGQAVQETVHAMKDIAGKINIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAERSQK
AAAEISQLSSTSVDVAVKAGDLLSKMVPDIQKTAELVQEISASSREQDTGAEQINKAIQQLDTVIQQNAGASEEMSSTAE
ELASQAELLTSSIAFFNIGEEGRSKPLVRHSKTTMKPMSFSKHPAKSAPIANVAGTDLQLNDDHFEHF
>Mature_548_residues
MKWFMNMKIKTKMGLGFTIVLALFTCAIAVTCFNMEQARKDSEQVASESVPFLMRAYDMNIAAIKLSETLTDVAATHNNE
GFKEAELAAVRFRQELAKYREMYMRENDEKSLREMDELGKSFDKFYDTGKKMALTYVSSGLVQGNTMMDGFDKDRALLSA
EIEKLQKSQSDEAKANTKGIVTTLNKVFLLLVAACGVAITLGILIAVFVTRSITVPLQSAVEVSNKLAEGDLTVVVTSEN
TDETGHLLAAMGNMVYKLREIVGEVQAATKNVASGSQELSSSSEQMSQGASEQAAAAEEASASMEQMTSNIRQNADNALQ
TEKIAVKSAENAKEGGQAVQETVHAMKDIAGKINIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAERSQK
AAAEISQLSSTSVDVAVKAGDLLSKMVPDIQKTAELVQEISASSREQDTGAEQINKAIQQLDTVIQQNAGASEEMSSTAE
ELASQAELLTSSIAFFNIGEEGRSKPLVRHSKTTMKPMSFSKHPAKSAPIANVAGTDLQLNDDHFEHF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=532, Percent_Identity=33.2706766917293, Blast_Score=209, Evalue=5e-55,
Organism=Escherichia coli, GI2367378, Length=335, Percent_Identity=37.0149253731343, Blast_Score=191, Evalue=8e-50,
Organism=Escherichia coli, GI1788194, Length=437, Percent_Identity=32.2654462242563, Blast_Score=183, Evalue=3e-47,
Organism=Escherichia coli, GI1788195, Length=332, Percent_Identity=35.8433734939759, Blast_Score=176, Evalue=4e-45,
Organism=Escherichia coli, GI1789453, Length=354, Percent_Identity=30.5084745762712, Blast_Score=152, Evalue=7e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 59235; Mature: 59235

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKWFMNMKIKTKMGLGFTIVLALFTCAIAVTCFNMEQARKDSEQVASESVPFLMRAYDMN
CCCEECCEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHCCC
IAAIKLSETLTDVAATHNNEGFKEAELAAVRFRQELAKYREMYMRENDEKSLREMDELGK
EEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SFDKFYDTGKKMALTYVSSGLVQGNTMMDGFDKDRALLSAEIEKLQKSQSDEAKANTKGI
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCHH
VTTLNKVFLLLVAACGVAITLGILIAVFVTRSITVPLQSAVEVSNKLAEGDLTVVVTSEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCC
TDETGHLLAAMGNMVYKLREIVGEVQAATKNVASGSQELSSSSEQMSQGASEQAAAAEEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHH
SASMEQMTSNIRQNADNALQTEKIAVKSAENAKEGGQAVQETVHAMKDIAGKINIIEEIA
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAERSQKAAAEISQLSSTSVDVAVKAG
HHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
DLLSKMVPDIQKTAELVQEISASSREQDTGAEQINKAIQQLDTVIQQNAGASEEMSSTAE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ELASQAELLTSSIAFFNIGEEGRSKPLVRHSKTTMKPMSFSKHPAKSAPIANVAGTDLQL
HHHHHHHHHHHHHHHEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
NDDHFEHF
CCCCCCCC
>Mature Secondary Structure
MKWFMNMKIKTKMGLGFTIVLALFTCAIAVTCFNMEQARKDSEQVASESVPFLMRAYDMN
CCCEECCEEEECCCCHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCHHHHHHCCC
IAAIKLSETLTDVAATHNNEGFKEAELAAVRFRQELAKYREMYMRENDEKSLREMDELGK
EEEEEHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
SFDKFYDTGKKMALTYVSSGLVQGNTMMDGFDKDRALLSAEIEKLQKSQSDEAKANTKGI
HHHHHHHCCHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCHH
VTTLNKVFLLLVAACGVAITLGILIAVFVTRSITVPLQSAVEVSNKLAEGDLTVVVTSEN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEEECCC
TDETGHLLAAMGNMVYKLREIVGEVQAATKNVASGSQELSSSSEQMSQGASEQAAAAEEA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHH
SASMEQMTSNIRQNADNALQTEKIAVKSAENAKEGGQAVQETVHAMKDIAGKINIIEEIA
HHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAERSQKAAAEISQLSSTSVDVAVKAG
HHHCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
DLLSKMVPDIQKTAELVQEISASSREQDTGAEQINKAIQQLDTVIQQNAGASEEMSSTAE
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
ELASQAELLTSSIAFFNIGEEGRSKPLVRHSKTTMKPMSFSKHPAKSAPIANVAGTDLQL
HHHHHHHHHHHHHHHEECCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEE
NDDHFEHF
CCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6374654; 9097039; 9278503 [H]