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The map label for this gene is mcp023 [H]

Identifier: 197119663

GI number: 197119663

Start: 3792563

End: 3794224

Strand: Direct

Name: mcp023 [H]

Synonym: Gbem_3298

Alternate gene names: 197119663

Gene position: 3792563-3794224 (Clockwise)

Preceding gene: 197119662

Following gene: 197119668

Centisome position: 82.18

GC content: 57.82

Gene sequence:

>1662_bases
ATGTTAAGCAATTTTAAAATTGGTACAAGATTACTGCTGTGCTTCGGCGTAGTCCTGCTCCTGCTTGTCGCCGTGGCGGG
CACCGGTTACTGGGGCATCAAGCAAGTTGAAGCCACCACAGACACCATGCTAGCTACCGAGGGACGCATCGCAGAGCACT
CAGCCAGGGCCCGGGCCAACATTCTGGGCATGAGGCGCTATGAGAAGGACATGCTCCTGAATATGGGCGAAGCTAAAAAG
GTCGAGGAATACCTCCAGAAATGGAACGCCGAGGCCGCCAAGATGACCGAGCGCGTCGCCGACCTGGAAAAATGCGCCGT
CGACAAAGAGGACAAGGACAAAACCAAGGAAATCAAGGAAAATTTCGATGGTTACAAGGCAGGTTTTGCGAAGGTAGCAG
CCGCTATTCAGAACGGAAAGCTGAAGACTGCACAAGAAGCAAACAGCGCTATAGCAGAGTACAAGGACAAGTCTCACCTG
ATGGAAGCGACGGCGGTCAGCCTGGCACAGGATGGCGTCAAGTCAATGCATGAAGCAGGGGCGAACATTGATAAAAAGGC
TAAGGAAATTGTTAATTACCTGCTCGCTATATCGTTGACAGCCGCAATTATGGCTGTCGCACTGAGTTTCCTGGTGACGC
GCAGCATCAGGCGTCCGCTGGAGGTCGGGGTTCAAACTGCGAACCGACTTGCTGCCGGAGATCTTACCATGGACATCGGC
GCGACCGGCAAGGACGAGACCGGTCAACTGCTGGCGGCGATGGGCAATATGGTGTCCAAGCTGAGGGAGATCGTAGGAGA
GGTGCAGGCCGCGACCAAGAACGTCGCCGCCGGAAGCCAGGAGCTCTCGTCCAGTTCAGAGGAGATGTCGCAGGGGGCCA
GCGAGCAGGCAGCGGCGGCTGAGGAAGCTTCCGCCAGCATGGAGCAGATGACCTCCAACATCCGCCAGAACGCGGACAAC
GCGCTGCAGACCGAGAAGATAGCGGTCAAGTCCGCTGACAACGCCAAGGAAGGTGGACAGGCTGTCCAGGAAACCGTACA
GGCCATGAAGGATATCGCCGGCAAGATCAACATCATCGAGGAGATCGCGCGGCAGACGAACCTATTGGCCCTGAACGCCG
CCATAGAGGCGGCCCGGGCCGGCGAGCACGGCAAGGGATTCGCCGTCGTCGCCAGCGAGGTGAGAAAACTGGCCGAGCGG
AGCCAGAAGGCTGCCGCCGAGATCTCGCAGCTCTCCAGCAACAGCGTAGATATCGCGGTAAAGGCAGGCGAGCTGTTATC
CAAGATGGTGCCAGACATCCAGAAGACGGCCGAACTGGTCCAGGAGATCAGCGCCTCCAGCAAAGAGCAGGACACGGGTG
CGGAGCAGATCAACAAGGCGATCCAGCAACTCGACACGGTCATCCAGCAAAACGCCAGCGCGTCGGAGGAAATGTCCTCG
ACCGCTGAGGAACTCGCCTCGCAGGCGGAACTGCTGTCAAGCTCCATCGCCTTCTTCAAGATCGAAGAGGGAAGGTCGAA
GTCCTTCGTTACTTCCACGAAGAACCCCGGCACAGTGAAGGCGATGAGCTTTAGCAAACACGCGGCCGCTCCTCGCGCAG
CGGCCGCAAACGTCGTGGGCACCGACCTGCAGCTGAACGACGAAGAGTTCGAACACTTCTAA

Upstream 100 bases:

>100_bases
TTCCGAAACTCCCATAATTTAATCAAGCAGTGTGTCGATAGTTAGAAAGCAGGGTGAAAGAGCGCCAAGCTTAAGAGATA
ACTAAATGGGGGGATCAGCG

Downstream 100 bases:

>100_bases
GAGCGCCGTTTAGAAAGAAAAAGCCGGGTTTCGCCTGCGACCACAAGGTCCGGCGAAACCCGGCTTTTTTTGTTTCCTCC
AGCTTCCCCTGGGAAGGGAC

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: MCP-I; Serine chemoreceptor protein [H]

Number of amino acids: Translated: 553; Mature: 553

Protein sequence:

>553_residues
MLSNFKIGTRLLLCFGVVLLLLVAVAGTGYWGIKQVEATTDTMLATEGRIAEHSARARANILGMRRYEKDMLLNMGEAKK
VEEYLQKWNAEAAKMTERVADLEKCAVDKEDKDKTKEIKENFDGYKAGFAKVAAAIQNGKLKTAQEANSAIAEYKDKSHL
MEATAVSLAQDGVKSMHEAGANIDKKAKEIVNYLLAISLTAAIMAVALSFLVTRSIRRPLEVGVQTANRLAAGDLTMDIG
ATGKDETGQLLAAMGNMVSKLREIVGEVQAATKNVAAGSQELSSSSEEMSQGASEQAAAAEEASASMEQMTSNIRQNADN
ALQTEKIAVKSADNAKEGGQAVQETVQAMKDIAGKINIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAER
SQKAAAEISQLSSNSVDIAVKAGELLSKMVPDIQKTAELVQEISASSKEQDTGAEQINKAIQQLDTVIQQNASASEEMSS
TAEELASQAELLSSSIAFFKIEEGRSKSFVTSTKNPGTVKAMSFSKHAAAPRAAAANVVGTDLQLNDEEFEHF

Sequences:

>Translated_553_residues
MLSNFKIGTRLLLCFGVVLLLLVAVAGTGYWGIKQVEATTDTMLATEGRIAEHSARARANILGMRRYEKDMLLNMGEAKK
VEEYLQKWNAEAAKMTERVADLEKCAVDKEDKDKTKEIKENFDGYKAGFAKVAAAIQNGKLKTAQEANSAIAEYKDKSHL
MEATAVSLAQDGVKSMHEAGANIDKKAKEIVNYLLAISLTAAIMAVALSFLVTRSIRRPLEVGVQTANRLAAGDLTMDIG
ATGKDETGQLLAAMGNMVSKLREIVGEVQAATKNVAAGSQELSSSSEEMSQGASEQAAAAEEASASMEQMTSNIRQNADN
ALQTEKIAVKSADNAKEGGQAVQETVQAMKDIAGKINIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAER
SQKAAAEISQLSSNSVDIAVKAGELLSKMVPDIQKTAELVQEISASSKEQDTGAEQINKAIQQLDTVIQQNASASEEMSS
TAEELASQAELLSSSIAFFKIEEGRSKSFVTSTKNPGTVKAMSFSKHAAAPRAAAANVVGTDLQLNDEEFEHF
>Mature_553_residues
MLSNFKIGTRLLLCFGVVLLLLVAVAGTGYWGIKQVEATTDTMLATEGRIAEHSARARANILGMRRYEKDMLLNMGEAKK
VEEYLQKWNAEAAKMTERVADLEKCAVDKEDKDKTKEIKENFDGYKAGFAKVAAAIQNGKLKTAQEANSAIAEYKDKSHL
MEATAVSLAQDGVKSMHEAGANIDKKAKEIVNYLLAISLTAAIMAVALSFLVTRSIRRPLEVGVQTANRLAAGDLTMDIG
ATGKDETGQLLAAMGNMVSKLREIVGEVQAATKNVAAGSQELSSSSEEMSQGASEQAAAAEEASASMEQMTSNIRQNADN
ALQTEKIAVKSADNAKEGGQAVQETVQAMKDIAGKINIIEEIARQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAER
SQKAAAEISQLSSNSVDIAVKAGELLSKMVPDIQKTAELVQEISASSKEQDTGAEQINKAIQQLDTVIQQNASASEEMSS
TAEELASQAELLSSSIAFFKIEEGRSKSFVTSTKNPGTVKAMSFSKHAAAPRAAAANVVGTDLQLNDEEFEHF

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=560, Percent_Identity=31.6071428571429, Blast_Score=213, Evalue=3e-56,
Organism=Escherichia coli, GI1787690, Length=326, Percent_Identity=40.4907975460123, Blast_Score=209, Evalue=4e-55,
Organism=Escherichia coli, GI1788194, Length=324, Percent_Identity=37.3456790123457, Blast_Score=191, Evalue=9e-50,
Organism=Escherichia coli, GI1788195, Length=278, Percent_Identity=38.4892086330935, Blast_Score=179, Evalue=5e-46,
Organism=Escherichia coli, GI1789453, Length=327, Percent_Identity=31.4984709480122, Blast_Score=150, Evalue=3e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR003122
- InterPro:   IPR004091
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF02203 TarH [H]

EC number: NA

Molecular weight: Translated: 58996; Mature: 58996

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLSNFKIGTRLLLCFGVVLLLLVAVAGTGYWGIKQVEATTDTMLATEGRIAEHSARARAN
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHH
ILGMRRYEKDMLLNMGEAKKVEEYLQKWNAEAAKMTERVADLEKCAVDKEDKDKTKEIKE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
NFDGYKAGFAKVAAAIQNGKLKTAQEANSAIAEYKDKSHLMEATAVSLAQDGVKSMHEAG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANIDKKAKEIVNYLLAISLTAAIMAVALSFLVTRSIRRPLEVGVQTANRLAAGDLTMDIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
ATGKDETGQLLAAMGNMVSKLREIVGEVQAATKNVAAGSQELSSSSEEMSQGASEQAAAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCCCHHHHHH
EEASASMEQMTSNIRQNADNALQTEKIAVKSADNAKEGGQAVQETVQAMKDIAGKINIIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EIARQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAERSQKAAAEISQLSSNSVDIAV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
KAGELLSKMVPDIQKTAELVQEISASSKEQDTGAEQINKAIQQLDTVIQQNASASEEMSS
EHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
TAEELASQAELLSSSIAFFKIEEGRSKSFVTSTKNPGTVKAMSFSKHAAAPRAAAANVVG
HHHHHHHHHHHHHHHHHEEEEECCCCCCCEECCCCCCEEEEECCHHHHCCCHHHHHHHHC
TDLQLNDEEFEHF
CCCEECHHHHCCC
>Mature Secondary Structure
MLSNFKIGTRLLLCFGVVLLLLVAVAGTGYWGIKQVEATTDTMLATEGRIAEHSARARAN
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEHHHHHHHHHHCCCCHHHHHHHHHHH
ILGMRRYEKDMLLNMGEAKKVEEYLQKWNAEAAKMTERVADLEKCAVDKEDKDKTKEIKE
HHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHH
NFDGYKAGFAKVAAAIQNGKLKTAQEANSAIAEYKDKSHLMEATAVSLAQDGVKSMHEAG
CCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
ANIDKKAKEIVNYLLAISLTAAIMAVALSFLVTRSIRRPLEVGVQTANRLAAGDLTMDIG
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECC
ATGKDETGQLLAAMGNMVSKLREIVGEVQAATKNVAAGSQELSSSSEEMSQGASEQAAAA
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCHHHHHCCCCHHHHHH
EEASASMEQMTSNIRQNADNALQTEKIAVKSADNAKEGGQAVQETVQAMKDIAGKINIIE
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHH
EIARQTNLLALNAAIEAARAGEHGKGFAVVASEVRKLAERSQKAAAEISQLSSNSVDIAV
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEE
KAGELLSKMVPDIQKTAELVQEISASSKEQDTGAEQINKAIQQLDTVIQQNASASEEMSS
EHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHH
TAEELASQAELLSSSIAFFKIEEGRSKSFVTSTKNPGTVKAMSFSKHAAAPRAAAANVVG
HHHHHHHHHHHHHHHHHEEEEECCCCCCCEECCCCCCEEEEECCHHHHCCCHHHHHHHHC
TDLQLNDEEFEHF
CCCEECHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6402709; 7610040; 9278503; 8384293; 6213619; 2033064; 10466731 [H]