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The map label for this gene is baeR [H]

Identifier: 197119661

GI number: 197119661

Start: 3789560

End: 3790231

Strand: Direct

Name: baeR [H]

Synonym: Gbem_3296

Alternate gene names: 197119661

Gene position: 3789560-3790231 (Clockwise)

Preceding gene: 308535361

Following gene: 197119662

Centisome position: 82.11

GC content: 60.12

Gene sequence:

>672_bases
ATGACACAAAGAGTGATGATCGTAGAGGACGAGGAGAAGCTGGCGAGCCTTTTGGGCGACTACCTGAAGCAGTCGGGTTT
CGAGACCATCTGGATAGCCGACGGCAACGAGGTGCTGCCGCGGGTGAGGGAACAACAACCCGACCTGATGCTGCTCGACC
TGATGCTCCCCGGGCGTGACGGCCTGGAAATCTGCAAGGAGATAAGAACCTTCTCGCAGCTCCCCATCATCATGATCACG
GCGCGGGTGGAAGAGATCGACCGCCTGCTCGGCCTGGAGCTTGGCGCCGACGACTACATCTGCAAGCCCTTCAGCCCCCG
CGAGGTGGTGGCCAGGGTAAAGACGGTGCTGCGGCGGACGGGCGAGCAGGCCCCGGCGCAGACACACGGCCTCACCCTCG
ACGCCGACCGCTATTTGGCGCTCTTCCATGGTCATGATCTAGAACTCACCGTGGTCGAGTTCAAGCTCTTGCACTTCCTC
TACCAGAACCCGGGCCGGATCTACTCCCGGAGCCAGTTGATGGACCGCATCTATTCGGACCAGCGCATCGTCAGCGACCG
CACCATCGACAGCCATATCAAGAAGCTGCGCAAAAAGATCGCCGCAGTAGCCCCCGACCAGGAGATCATCTATTCCATAT
ATGGTGCAGGGTACAAGTACGAGCCGGCGTAA

Upstream 100 bases:

>100_bases
AGAACATCGTGGAGGCCCACGAAGGAACCATATCCGCCCTCCCTTCCCCGCACGGCGGGGTGCTGATCAGGGTGGAACTG
CCGCTTACCGGGAGCAGGAC

Downstream 100 bases:

>100_bases
CCCTCCCCTGCTCTTCATTTACCTTCGACTACTCCCCCTCCGGCCTTTACAGCCTTGCCTCACGCCCCCCACTCAGGATA
ATCGAAATTCCACCTTCGAA

Product: winged-helix transcriptional response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MTQRVMIVEDEEKLASLLGDYLKQSGFETIWIADGNEVLPRVREQQPDLMLLDLMLPGRDGLEICKEIRTFSQLPIIMIT
ARVEEIDRLLGLELGADDYICKPFSPREVVARVKTVLRRTGEQAPAQTHGLTLDADRYLALFHGHDLELTVVEFKLLHFL
YQNPGRIYSRSQLMDRIYSDQRIVSDRTIDSHIKKLRKKIAAVAPDQEIIYSIYGAGYKYEPA

Sequences:

>Translated_223_residues
MTQRVMIVEDEEKLASLLGDYLKQSGFETIWIADGNEVLPRVREQQPDLMLLDLMLPGRDGLEICKEIRTFSQLPIIMIT
ARVEEIDRLLGLELGADDYICKPFSPREVVARVKTVLRRTGEQAPAQTHGLTLDADRYLALFHGHDLELTVVEFKLLHFL
YQNPGRIYSRSQLMDRIYSDQRIVSDRTIDSHIKKLRKKIAAVAPDQEIIYSIYGAGYKYEPA
>Mature_222_residues
TQRVMIVEDEEKLASLLGDYLKQSGFETIWIADGNEVLPRVREQQPDLMLLDLMLPGRDGLEICKEIRTFSQLPIIMITA
RVEEIDRLLGLELGADDYICKPFSPREVVARVKTVLRRTGEQAPAQTHGLTLDADRYLALFHGHDLELTVVEFKLLHFLY
QNPGRIYSRSQLMDRIYSDQRIVSDRTIDSHIKKLRKKIAAVAPDQEIIYSIYGAGYKYEPA

Specific function: Member of the two-component regulatory system BaeS/BaeR. Activates the mdtABCD operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1788394, Length=224, Percent_Identity=54.9107142857143, Blast_Score=254, Evalue=2e-69,
Organism=Escherichia coli, GI1786599, Length=226, Percent_Identity=40.2654867256637, Blast_Score=179, Evalue=1e-46,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=44.1441441441441, Blast_Score=175, Evalue=2e-45,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=36.6812227074236, Blast_Score=148, Evalue=3e-37,
Organism=Escherichia coli, GI2367329, Length=226, Percent_Identity=39.3805309734513, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=33.7662337662338, Blast_Score=136, Evalue=1e-33,
Organism=Escherichia coli, GI1789402, Length=218, Percent_Identity=34.4036697247706, Blast_Score=130, Evalue=7e-32,
Organism=Escherichia coli, GI1787229, Length=229, Percent_Identity=35.3711790393013, Blast_Score=129, Evalue=2e-31,
Organism=Escherichia coli, GI1787375, Length=222, Percent_Identity=34.2342342342342, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI87082012, Length=218, Percent_Identity=31.651376146789, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786911, Length=220, Percent_Identity=30, Blast_Score=111, Evalue=4e-26,
Organism=Escherichia coli, GI1786784, Length=223, Percent_Identity=33.6322869955157, Blast_Score=105, Evalue=2e-24,
Organism=Escherichia coli, GI145693140, Length=236, Percent_Identity=28.8135593220339, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI1790552, Length=218, Percent_Identity=31.651376146789, Blast_Score=95, Evalue=4e-21,
Organism=Escherichia coli, GI1788550, Length=103, Percent_Identity=33.9805825242718, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1790299, Length=120, Percent_Identity=32.5, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1787487, Length=102, Percent_Identity=34.3137254901961, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25606; Mature: 25475

Theoretical pI: Translated: 5.70; Mature: 5.70

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQRVMIVEDEEKLASLLGDYLKQSGFETIWIADGNEVLPRVREQQPDLMLLDLMLPGRD
CCCEEEEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEEEECCCCC
GLEICKEIRTFSQLPIIMITARVEEIDRLLGLELGADDYICKPFSPREVVARVKTVLRRT
HHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHC
GEQAPAQTHGLTLDADRYLALFHGHDLELTVVEFKLLHFLYQNPGRIYSRSQLMDRIYSD
CCCCCCHHCCEEECCCCEEEEEECCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
QRIVSDRTIDSHIKKLRKKIAAVAPDQEIIYSIYGAGYKYEPA
CHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCC
>Mature Secondary Structure 
TQRVMIVEDEEKLASLLGDYLKQSGFETIWIADGNEVLPRVREQQPDLMLLDLMLPGRD
CCEEEEEECHHHHHHHHHHHHHHCCCCEEEEECCHHHHHHHHHCCCCEEEEEEECCCCC
GLEICKEIRTFSQLPIIMITARVEEIDRLLGLELGADDYICKPFSPREVVARVKTVLRRT
HHHHHHHHHHHHCCCEEEEHHHHHHHHHHHCCCCCCCCCEECCCCHHHHHHHHHHHHHHC
GEQAPAQTHGLTLDADRYLALFHGHDLELTVVEFKLLHFLYQNPGRIYSRSQLMDRIYSD
CCCCCCHHCCEEECCCCEEEEEECCCCEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
QRIVSDRTIDSHIKKLRKKIAAVAPDQEIIYSIYGAGYKYEPA
CHHHHCCHHHHHHHHHHHHHHHCCCCHHHHHHHHCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]