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The map label for this gene is prt [H]

Identifier: 197117250

GI number: 197117250

Start: 1013787

End: 1014698

Strand: Direct

Name: prt [H]

Synonym: Gbem_0858

Alternate gene names: 197117250

Gene position: 1013787-1014698 (Clockwise)

Preceding gene: 197117249

Following gene: 197117251

Centisome position: 21.97

GC content: 59.54

Gene sequence:

>912_bases
ATGAAGATCCTCGTCACCGGTGCGACCGGTTTCCTGGGAAGCCGTCTGGTAGAAGCCCTGCTCCGACAGGGGCACCAGGT
CATCGTCTTGAAGCGCAGTTTTTCCGATACGCGGCGGCTGAAGGGGATGCTCTCTTCGATTGCCCTTTACGATTTGGACC
GGTCCCCCCTGGCCGACCCGTTCCGGGAGCACGGCACGCTCGACGCGGTGCTGCATGCCGCCACCTGCTACGGCCGCCGG
GGCGAGAGTTCCAGCGAGATCTGCGAAGCAAACGTGGCCTTTCCGTTACGTCTTCTGGAAGCCGCATGCAGTCATGGAAC
CGCTCGGTTTATCAATACCGATACCAGCCTGTACAGGGGCATCAACGCCTACGCCCTGTCCAAGAAGCAGTTTTCGGAGT
GGGGGAAGCTTGCGGCGGAGAGCGGACGGATCCGTTTCGTGAACGTGGTGCTCGAGCATTTTTATGGGCCAGGGGACGAT
GACGGCAAATTCGTCTCCCATGTCATCAAGAGCTGTCGCCAGGGAGTGCCGGAACTGAAGCTCACCAAGGGGGAACAGGA
ACGGGATTTCATCTACATCGATGACGTCGTTTCCGCTTATCTACTCCTGCTTCAGGAGACGGGCTGCTCTGAGCCGGCAT
GCGCTGACTATCCACTGGGATCCGGGCAAACAGTATCACTGCGCGCCCTGGTGGAGATGATCGGCCGGCTGACCGGATCG
ACGACGAAACTGAACTTCGGCGCGCTCCCGTACCGGCAAAACGAGGCCATGCACTCAGTTGCGGACATCGTTGCACTTGA
GCGGCTTGGCTGGAAGGCAACTGTGGATCTCTCGGCAGGGCTTGCGCGCACCGTAGCCTACCAGCAACAGGAAGACAAAA
ACGGCAGTGAAGCTGAAGGGAGCATGTCATGA

Upstream 100 bases:

>100_bases
ACCGGATCATGAACGACACCTTATGGATCGGCGTCTATCCGGGGATGACGGAAGCCATGCTCGCGCAGATGATCGAGAAA
ATCAGGGAAGTTGCTGGGGC

Downstream 100 bases:

>100_bases
AATTACTGATAACCGGCGGGTGCGGTTTTCTCGGAAGCAATTTGGCAGCACACGCGCTCAAGCGCGGGGACGAACTCGTC
GTCTTTGACAGCCTGTACCG

Product: CDP-paratose synthase

Products: UDPglucoseal [C]

Alternate protein names: NA

Number of amino acids: Translated: 303; Mature: 303

Protein sequence:

>303_residues
MKILVTGATGFLGSRLVEALLRQGHQVIVLKRSFSDTRRLKGMLSSIALYDLDRSPLADPFREHGTLDAVLHAATCYGRR
GESSSEICEANVAFPLRLLEAACSHGTARFINTDTSLYRGINAYALSKKQFSEWGKLAAESGRIRFVNVVLEHFYGPGDD
DGKFVSHVIKSCRQGVPELKLTKGEQERDFIYIDDVVSAYLLLLQETGCSEPACADYPLGSGQTVSLRALVEMIGRLTGS
TTKLNFGALPYRQNEAMHSVADIVALERLGWKATVDLSAGLARTVAYQQQEDKNGSEAEGSMS

Sequences:

>Translated_303_residues
MKILVTGATGFLGSRLVEALLRQGHQVIVLKRSFSDTRRLKGMLSSIALYDLDRSPLADPFREHGTLDAVLHAATCYGRR
GESSSEICEANVAFPLRLLEAACSHGTARFINTDTSLYRGINAYALSKKQFSEWGKLAAESGRIRFVNVVLEHFYGPGDD
DGKFVSHVIKSCRQGVPELKLTKGEQERDFIYIDDVVSAYLLLLQETGCSEPACADYPLGSGQTVSLRALVEMIGRLTGS
TTKLNFGALPYRQNEAMHSVADIVALERLGWKATVDLSAGLARTVAYQQQEDKNGSEAEGSMS
>Mature_303_residues
MKILVTGATGFLGSRLVEALLRQGHQVIVLKRSFSDTRRLKGMLSSIALYDLDRSPLADPFREHGTLDAVLHAATCYGRR
GESSSEICEANVAFPLRLLEAACSHGTARFINTDTSLYRGINAYALSKKQFSEWGKLAAESGRIRFVNVVLEHFYGPGDD
DGKFVSHVIKSCRQGVPELKLTKGEQERDFIYIDDVVSAYLLLLQETGCSEPACADYPLGSGQTVSLRALVEMIGRLTGS
TTKLNFGALPYRQNEAMHSVADIVALERLGWKATVDLSAGLARTVAYQQQEDKNGSEAEGSMS

Specific function: Galactose metabolism; third step. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: 5.1.3.2 [C]

Molecular weight: Translated: 33129; Mature: 33129

Theoretical pI: Translated: 6.87; Mature: 6.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILVTGATGFLGSRLVEALLRQGHQVIVLKRSFSDTRRLKGMLSSIALYDLDRSPLADP
CEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCH
FREHGTLDAVLHAATCYGRRGESSSEICEANVAFPLRLLEAACSHGTARFINTDTSLYRG
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHHHC
INAYALSKKQFSEWGKLAAESGRIRFVNVVLEHFYGPGDDDGKFVSHVIKSCRQGVPELK
CHHHHHCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEE
LTKGEQERDFIYIDDVVSAYLLLLQETGCSEPACADYPLGSGQTVSLRALVEMIGRLTGS
ECCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCC
TTKLNFGALPYRQNEAMHSVADIVALERLGWKATVDLSAGLARTVAYQQQEDKNGSEAEG
CEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCC
SMS
CCC
>Mature Secondary Structure
MKILVTGATGFLGSRLVEALLRQGHQVIVLKRSFSDTRRLKGMLSSIALYDLDRSPLADP
CEEEEECCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCH
FREHGTLDAVLHAATCYGRRGESSSEICEANVAFPLRLLEAACSHGTARFINTDTSLYRG
HHHCCCHHHHHHHHHHHCCCCCCHHHHHHCCCHHHHHHHHHHHCCCCEEEEECCHHHHHC
INAYALSKKQFSEWGKLAAESGRIRFVNVVLEHFYGPGDDDGKFVSHVIKSCRQGVPELK
CHHHHHCHHHHHHHHHHHHCCCCEEHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCEE
LTKGEQERDFIYIDDVVSAYLLLLQETGCSEPACADYPLGSGQTVSLRALVEMIGRLTGS
ECCCCCCCCEEEHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHCCC
TTKLNFGALPYRQNEAMHSVADIVALERLGWKATVDLSAGLARTVAYQQQEDKNGSEAEG
CEEEECCCCCCCCCHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCC
SMS
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NAD+ [C]

Metal ions: NA

Kcat value (1/min): 57600 [C]

Specific activity: 233.3

Km value (mM): 0.256 {UDPgalactose}} 0.225 {UDPgalactose}} 0.2 {UDPgalactose}} 0.18 {UDPgalactose}} 0.16 {UDPgalactose}} 0.14 {UDPgalactose}} 0.048 {UDPgalactose}} 0.026 {UDPgalactose}} [C]

Substrates: UDPglucose [C]

Specific reaction: UDPglucose <==> UDPglucoseal [C]

General reaction: Epimerization (specificity for carbon forming a hexosulose) [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1379320 [H]