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The map label for this gene is coaE [H]

Identifier: 197117054

GI number: 197117054

Start: 779409

End: 780029

Strand: Reverse

Name: coaE [H]

Synonym: Gbem_0657

Alternate gene names: 197117054

Gene position: 780029-779409 (Counterclockwise)

Preceding gene: 197117058

Following gene: 197117052

Centisome position: 16.9

GC content: 67.63

Gene sequence:

>621_bases
ATGCGCATCATAGGGCTCACTGGGGGAATAGCCTCGGGAAAAACGAGCGTGGCGAACCTCCTGGAACGGCTCGGCGCGCC
GGTCGTCGACGCGGACCAACTGGCCCGGGAGGTGGTGGAACCGGGCGAGCGGGCGCTGGCGCAGATAGCGGAGAGCTTCG
GCAAGGCGGTCTTGAATGCGGACGGAAGCCTGAACCGGGCGGCCCTTGGGGAGATCGTCTTCGCCGACCCGGAGAAAAGG
CGAAAGCTTGAGTCGATCACCCACCCCGCCATCAAGGAGCGGGCCGAGGAGAAGCTCGCGCGGCTAAAGGCTGCGGGGGC
GAAGACCGCCTTCTACGTGGCGCCGCTCCTGATCGAAGCGGGGATCACCTCTAGGGTGCACGAGGTCTGGGTGGTCTACC
TCGACCACGAGACCCAGTTGGCCCGCCTCATGGCGCGGGACGGGCTCTCGCGCGAGGCGGCGCTTTCGCGCATCGCTTCG
CAGATGCCGATGGAGGAGAAGAAGCGGCTGGGAAGGGTCGTGATCGACAACCGGGGGAGCAGGGAGGATCTGGAGGCAGA
GGTGCTAAGGGTCTGGCGCGAGGAGATCGCGGCCGGGCAGCCCCCCCCCGCCGAACCGTAG

Upstream 100 bases:

>100_bases
GAGGACCTGACCAACCCGACCTTCGCCCTGGGCGAACAGGGAATCATCTACTCATGAAACCAGCCTCACCCGACTACAAA
TCGTTGCGCCGGAGTGAGCG

Downstream 100 bases:

>100_bases
AACTGAAAAAGAAAAGGCCCCGCGAACGGGGCCTTTTCTTTATTTGTGGTAGCCGAGCTTGTGGGAGATCTCCTCGCCGG
AGCGAATCACCAGCGGGATC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 206; Mature: 206

Protein sequence:

>206_residues
MRIIGLTGGIASGKTSVANLLERLGAPVVDADQLAREVVEPGERALAQIAESFGKAVLNADGSLNRAALGEIVFADPEKR
RKLESITHPAIKERAEEKLARLKAAGAKTAFYVAPLLIEAGITSRVHEVWVVYLDHETQLARLMARDGLSREAALSRIAS
QMPMEEKKRLGRVVIDNRGSREDLEAEVLRVWREEIAAGQPPPAEP

Sequences:

>Translated_206_residues
MRIIGLTGGIASGKTSVANLLERLGAPVVDADQLAREVVEPGERALAQIAESFGKAVLNADGSLNRAALGEIVFADPEKR
RKLESITHPAIKERAEEKLARLKAAGAKTAFYVAPLLIEAGITSRVHEVWVVYLDHETQLARLMARDGLSREAALSRIAS
QMPMEEKKRLGRVVIDNRGSREDLEAEVLRVWREEIAAGQPPPAEP
>Mature_206_residues
MRIIGLTGGIASGKTSVANLLERLGAPVVDADQLAREVVEPGERALAQIAESFGKAVLNADGSLNRAALGEIVFADPEKR
RKLESITHPAIKERAEEKLARLKAAGAKTAFYVAPLLIEAGITSRVHEVWVVYLDHETQLARLMARDGLSREAALSRIAS
QMPMEEKKRLGRVVIDNRGSREDLEAEVLRVWREEIAAGQPPPAEP

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=180, Percent_Identity=42.2222222222222, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI191252795, Length=180, Percent_Identity=42.2222222222222, Blast_Score=152, Evalue=2e-37,
Organism=Homo sapiens, GI110227607, Length=192, Percent_Identity=35.9375, Blast_Score=118, Evalue=3e-27,
Organism=Homo sapiens, GI205277394, Length=192, Percent_Identity=35.9375, Blast_Score=118, Evalue=4e-27,
Organism=Homo sapiens, GI110227605, Length=192, Percent_Identity=35.9375, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI110227603, Length=192, Percent_Identity=35.9375, Blast_Score=118, Evalue=5e-27,
Organism=Homo sapiens, GI110227601, Length=192, Percent_Identity=35.9375, Blast_Score=118, Evalue=5e-27,
Organism=Escherichia coli, GI1786292, Length=189, Percent_Identity=40.2116402116402, Blast_Score=132, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI17554944, Length=193, Percent_Identity=38.860103626943, Blast_Score=154, Evalue=2e-38,
Organism=Caenorhabditis elegans, GI25143409, Length=189, Percent_Identity=35.4497354497354, Blast_Score=91, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6320402, Length=193, Percent_Identity=38.3419689119171, Blast_Score=123, Evalue=2e-29,
Organism=Drosophila melanogaster, GI24644728, Length=193, Percent_Identity=41.4507772020725, Blast_Score=158, Evalue=3e-39,
Organism=Drosophila melanogaster, GI24658602, Length=193, Percent_Identity=33.160621761658, Blast_Score=120, Evalue=5e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22429; Mature: 22429

Theoretical pI: Translated: 6.82; Mature: 6.82

Prosite motif: PS01294 COAE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIGLTGGIASGKTSVANLLERLGAPVVDADQLAREVVEPGERALAQIAESFGKAVLNA
CEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
DGSLNRAALGEIVFADPEKRRKLESITHPAIKERAEEKLARLKAAGAKTAFYVAPLLIEA
CCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GITSRVHEVWVVYLDHETQLARLMARDGLSREAALSRIASQMPMEEKKRLGRVVIDNRGS
HHHHHHHHHEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCEEECCCCC
REDLEAEVLRVWREEIAAGQPPPAEP
HHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MRIIGLTGGIASGKTSVANLLERLGAPVVDADQLAREVVEPGERALAQIAESFGKAVLNA
CEEEEECCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHCC
DGSLNRAALGEIVFADPEKRRKLESITHPAIKERAEEKLARLKAAGAKTAFYVAPLLIEA
CCCCCHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GITSRVHEVWVVYLDHETQLARLMARDGLSREAALSRIASQMPMEEKKRLGRVVIDNRGS
HHHHHHHHHEEEEECCHHHHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHCCCEEECCCCC
REDLEAEVLRVWREEIAAGQPPPAEP
HHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA