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The map label for this gene is atoS [H]

Identifier: 197117052

GI number: 197117052

Start: 776632

End: 778260

Strand: Reverse

Name: atoS [H]

Synonym: Gbem_0655

Alternate gene names: 197117052

Gene position: 778260-776632 (Counterclockwise)

Preceding gene: 197117054

Following gene: 197117051

Centisome position: 16.86

GC content: 61.94

Gene sequence:

>1629_bases
GTGCGTCTCAACCTGATTTCCAAACTTGCCATCGCCACCAGCCTGGTGCTCTTGAGCACCATGGCGCTCTTCGCCTATCT
CAATTTCCGTAGCCTTCAGGGCCTGCTTTTGCAGGAGGCCATCTCCGAGGCGGACCGCATCAGCGAAACCATACTGCGCA
CCACCCACAACCAGATGCTCAGGGACGACCGCCCAATGTTCTACAAGACCCTGGAGGAGATGGGGAGCCAGCAGGAGGTG
GAGCGGATCAGGCTGATCAACAAGACCGGACGCATCATCTTCTCCACCAAGGACGCCGAAACCGGGTTCCTGCTGAAAAA
GAACACCGAGGTCTGCGCCGTCTGCCATGGAACCACCCAGCTCCTGCTGACCGCCTCCTCCAAGCACAGGAGCCGGCGCT
TTTTCAGCGAAAGCGGCGGCGAGCTTCTGGGGATCACCAGCGCCATCTACAACGAGGAAAGCTGCTACACGGCAAGCTGC
CACTTCCACCCGGAAAACTTCAAGGTGCTGGGGGTTCTCGACGTGGTGGTCCCGCTGGACCGGATGCACTCGGTCCTGGA
CGCCTTCCGCAACCGCAGCATCGCCCTCACCGTTTTGGTCCTCACCCTCACCGCCCTTTGCATCACCCTCTTCACCCAAA
AACTGGTGAACCGCCCGGTGCGCGAGCTTCTGGAGCACACCCAGATGCTCTCGCGTGGGGAGCTGGACGGCCTGGTGGAA
GGGTTCGCCAACGACGAACTGGGGGAACTCGCCGACTCCTTTAACGCCATGACCCTGAACCTGAAAAGGGCGCGCCAGGA
CCTGGAGGGATGGGGGCGGGACCTGGAAGAGATGGTGCAGCAAAGAACCTACGAAGTGACCCAGATGCAGGCGCAACTGA
TCCGCAGCGAAAAGCTTGCCTCGTTAGGCGAGCTGGTAGCCGGCATCGCGCACGAGATCAACAACCCCCTCACCGGGATC
CTGGTCTTCGCCTCGCTGATCCAGAGCAACAAGAAGCTCGATGAAACGCTCAGAAACGACATAGAGACGGTGATCAGGGA
GACCAAGCGCTGCGCGGGGATCGTAAAGGGGCTTCTGGAGTTCGCCCGCTGCTCGCCCCCCCAAAAGGAGCTGCACAGCC
TGAGCGACATCTCGGAGGCGGCGCTCACCCTGATCCAGCACCAGATACTGTTCCAGGACGTGAGCATCATCCGCGAGTAC
GCAAGCGATCTCCCCAAGCTTTTGATCGACGCGAATCAGATCGAACAGGTGCTGGTCAACATGTTCGTCAACGCCGGGCA
CGCCATGCTCGGCGAAGGGGTGCTGCACATCGCGACCGGTATGGAATCGGACGAGGGGGCGGCCTTCATCAGGATCGTGG
ACAACGGCTGCGGCATCTCCGAGCAAAACCTCACCAAGATCTTCGACCCCTTCTTCTCCACCAAGGCCAACAAAGGAACC
GGCCTCGGGCTCTCCGTCTCCTACGGGATCGTGCAGGAGCACGGCGGGCGCATCGACGTCACCAGCGAAATCGGGGTGGG
GACCGCCTTCACCGTGACCCTCCCCCTCCCCGACCGCGCATCCGTCACCCCCCTGGCACCCACCCCGCTCTCCCCCCCCG
GCGACCCGTCCTCCCTTCCCTGCGCCTGA

Upstream 100 bases:

>100_bases
ATAATGTTCTAAAGAAGTCAAGCAGCAAAAAAGCATGTCGCCATGCGATTTTAAAACAGGACCAACACGACTGAGGCAGC
ATCCCGAGGACGGAGAGCCT

Downstream 100 bases:

>100_bases
TCCTGTATACGAGACGACTGCTCCCCCTTCCTCCCCCTCGCGGCAGCGCAACTGCGCGGAAGAAAACGATTGACAGCGGC
AAGGCATATTGATAGTTTAC

Product: HAMP domain-containing sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 542; Mature: 542

Protein sequence:

>542_residues
MRLNLISKLAIATSLVLLSTMALFAYLNFRSLQGLLLQEAISEADRISETILRTTHNQMLRDDRPMFYKTLEEMGSQQEV
ERIRLINKTGRIIFSTKDAETGFLLKKNTEVCAVCHGTTQLLLTASSKHRSRRFFSESGGELLGITSAIYNEESCYTASC
HFHPENFKVLGVLDVVVPLDRMHSVLDAFRNRSIALTVLVLTLTALCITLFTQKLVNRPVRELLEHTQMLSRGELDGLVE
GFANDELGELADSFNAMTLNLKRARQDLEGWGRDLEEMVQQRTYEVTQMQAQLIRSEKLASLGELVAGIAHEINNPLTGI
LVFASLIQSNKKLDETLRNDIETVIRETKRCAGIVKGLLEFARCSPPQKELHSLSDISEAALTLIQHQILFQDVSIIREY
ASDLPKLLIDANQIEQVLVNMFVNAGHAMLGEGVLHIATGMESDEGAAFIRIVDNGCGISEQNLTKIFDPFFSTKANKGT
GLGLSVSYGIVQEHGGRIDVTSEIGVGTAFTVTLPLPDRASVTPLAPTPLSPPGDPSSLPCA

Sequences:

>Translated_542_residues
MRLNLISKLAIATSLVLLSTMALFAYLNFRSLQGLLLQEAISEADRISETILRTTHNQMLRDDRPMFYKTLEEMGSQQEV
ERIRLINKTGRIIFSTKDAETGFLLKKNTEVCAVCHGTTQLLLTASSKHRSRRFFSESGGELLGITSAIYNEESCYTASC
HFHPENFKVLGVLDVVVPLDRMHSVLDAFRNRSIALTVLVLTLTALCITLFTQKLVNRPVRELLEHTQMLSRGELDGLVE
GFANDELGELADSFNAMTLNLKRARQDLEGWGRDLEEMVQQRTYEVTQMQAQLIRSEKLASLGELVAGIAHEINNPLTGI
LVFASLIQSNKKLDETLRNDIETVIRETKRCAGIVKGLLEFARCSPPQKELHSLSDISEAALTLIQHQILFQDVSIIREY
ASDLPKLLIDANQIEQVLVNMFVNAGHAMLGEGVLHIATGMESDEGAAFIRIVDNGCGISEQNLTKIFDPFFSTKANKGT
GLGLSVSYGIVQEHGGRIDVTSEIGVGTAFTVTLPLPDRASVTPLAPTPLSPPGDPSSLPCA
>Mature_542_residues
MRLNLISKLAIATSLVLLSTMALFAYLNFRSLQGLLLQEAISEADRISETILRTTHNQMLRDDRPMFYKTLEEMGSQQEV
ERIRLINKTGRIIFSTKDAETGFLLKKNTEVCAVCHGTTQLLLTASSKHRSRRFFSESGGELLGITSAIYNEESCYTASC
HFHPENFKVLGVLDVVVPLDRMHSVLDAFRNRSIALTVLVLTLTALCITLFTQKLVNRPVRELLEHTQMLSRGELDGLVE
GFANDELGELADSFNAMTLNLKRARQDLEGWGRDLEEMVQQRTYEVTQMQAQLIRSEKLASLGELVAGIAHEINNPLTGI
LVFASLIQSNKKLDETLRNDIETVIRETKRCAGIVKGLLEFARCSPPQKELHSLSDISEAALTLIQHQILFQDVSIIREY
ASDLPKLLIDANQIEQVLVNMFVNAGHAMLGEGVLHIATGMESDEGAAFIRIVDNGCGISEQNLTKIFDPFFSTKANKGT
GLGLSVSYGIVQEHGGRIDVTSEIGVGTAFTVTLPLPDRASVTPLAPTPLSPPGDPSSLPCA

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=229, Percent_Identity=38.4279475982533, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI1790436, Length=235, Percent_Identity=37.4468085106383, Blast_Score=130, Evalue=3e-31,
Organism=Escherichia coli, GI87081816, Length=350, Percent_Identity=29.1428571428571, Blast_Score=115, Evalue=6e-27,
Organism=Escherichia coli, GI1790300, Length=236, Percent_Identity=35.1694915254237, Blast_Score=105, Evalue=5e-24,
Organism=Escherichia coli, GI1789149, Length=313, Percent_Identity=25.5591054313099, Blast_Score=98, Evalue=2e-21,
Organism=Escherichia coli, GI1789808, Length=222, Percent_Identity=27.4774774774775, Blast_Score=75, Evalue=8e-15,
Organism=Escherichia coli, GI145693157, Length=257, Percent_Identity=27.2373540856031, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI48994928, Length=277, Percent_Identity=26.7148014440433, Blast_Score=66, Evalue=5e-12,
Organism=Escherichia coli, GI1788713, Length=249, Percent_Identity=25.7028112449799, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1787894, Length=230, Percent_Identity=27.8260869565217, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786600, Length=262, Percent_Identity=25.1908396946565, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1786783, Length=256, Percent_Identity=24.609375, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 59753; Mature: 59753

Theoretical pI: Translated: 5.50; Mature: 5.50

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLNLISKLAIATSLVLLSTMALFAYLNFRSLQGLLLQEAISEADRISETILRTTHNQML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDDRPMFYKTLEEMGSQQEVERIRLINKTGRIIFSTKDAETGFLLKKNTEVCAVCHGTTQ
HCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCEE
LLLTASSKHRSRRFFSESGGELLGITSAIYNEESCYTASCHFHPENFKVLGVLDVVVPLD
EEEEECHHHHHHHHHHHCCCCEEEHHHHHHCCCCCEEEEEEECCCCEEEEEHHHHHHHHH
RMHSVLDAFRNRSIALTVLVLTLTALCITLFTQKLVNRPVRELLEHTQMLSRGELDGLVE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GFANDELGELADSFNAMTLNLKRARQDLEGWGRDLEEMVQQRTYEVTQMQAQLIRSEKLA
HHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGELVAGIAHEINNPLTGILVFASLIQSNKKLDETLRNDIETVIRETKRCAGIVKGLLE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FARCSPPQKELHSLSDISEAALTLIQHQILFQDVSIIREYASDLPKLLIDANQIEQVLVN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
MFVNAGHAMLGEGVLHIATGMESDEGAAFIRIVDNGCGISEQNLTKIFDPFFSTKANKGT
HHHHCCHHHHHCCHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCC
GLGLSVSYGIVQEHGGRIDVTSEIGVGTAFTVTLPLPDRASVTPLAPTPLSPPGDPSSLP
CCCEEEEHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
CA
CC
>Mature Secondary Structure
MRLNLISKLAIATSLVLLSTMALFAYLNFRSLQGLLLQEAISEADRISETILRTTHNQML
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDDRPMFYKTLEEMGSQQEVERIRLINKTGRIIFSTKDAETGFLLKKNTEVCAVCHGTTQ
HCCCCHHHHHHHHHCCHHHHHHHHHHHCCCCEEEEECCCCCCEEEECCCCEEEEECCCEE
LLLTASSKHRSRRFFSESGGELLGITSAIYNEESCYTASCHFHPENFKVLGVLDVVVPLD
EEEEECHHHHHHHHHHHCCCCEEEHHHHHHCCCCCEEEEEEECCCCEEEEEHHHHHHHHH
RMHSVLDAFRNRSIALTVLVLTLTALCITLFTQKLVNRPVRELLEHTQMLSRGELDGLVE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHH
GFANDELGELADSFNAMTLNLKRARQDLEGWGRDLEEMVQQRTYEVTQMQAQLIRSEKLA
HHCCCHHHHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SLGELVAGIAHEINNPLTGILVFASLIQSNKKLDETLRNDIETVIRETKRCAGIVKGLLE
HHHHHHHHHHHHHCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FARCSPPQKELHSLSDISEAALTLIQHQILFQDVSIIREYASDLPKLLIDANQIEQVLVN
HHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHH
MFVNAGHAMLGEGVLHIATGMESDEGAAFIRIVDNGCGISEQNLTKIFDPFFSTKANKGT
HHHHCCHHHHHCCHHHHCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCC
GLGLSVSYGIVQEHGGRIDVTSEIGVGTAFTVTLPLPDRASVTPLAPTPLSPPGDPSSLP
CCCEEEEHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCC
CA
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]