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The map label for this gene is tdcG [H]

Identifier: 194737040

GI number: 194737040

Start: 3312532

End: 3313896

Strand: Reverse

Name: tdcG [H]

Synonym: SeSA_A3431

Alternate gene names: 194737040

Gene position: 3313896-3312532 (Counterclockwise)

Preceding gene: 194735585

Following gene: 194736541

Centisome position: 70.37

GC content: 56.41

Gene sequence:

>1365_bases
ATGATTAGCGCATTTGATATTTTTAAGATTGGCATTGGACCTTCAAGCTCCCATACCGTAGGGCCAATGAATGCAGGAAA
ATGTTTTATCGATCGGCTGAACGACAGCGGCGACCTGCCGCGAACGACGCGCATCACGGTTGATCTTTACGGATCGCTAT
CGCTGACGGGCAAAGGCCACGCGACCGATACCGCCATCATTATGGGCCTGGCAGGCAATACGCCGCAGGATGTCAATATT
GATAGCATTCCGGCGTTTATCCAGGAGGTTGTCCGCAGCAGCCGTTTATCGGTGGCGGGTGGCGCGCATGTGGTGGATTT
TCCCGTCGCCGACAGTATTCTCTTTCACGCTGAAACCCTGGCGCGCCATGAAAACGGTATGCGAATTACCGCCTGGAACG
GACAAACGCCGCTTTTACACAAAACGTATTACTCTATTGGCGGCGGCTTTATTGTCGAAGAGGAACGCTTTGGTCAGTCG
CACGACGTAGAAAAATCGGTGCCGTATGATTTTCATTCCGCCAGCGAACTGCTGACGCTGTGTGAAAGACAGGGGCTCTC
GGTTTCCGGCCTGATGATGCAAAATGAACTGGCGTTGCGGAGCAAAGAGCAGATTGACGCTGGCTTTGCCCGCATCTGGC
AGGTGATGGAGACCGGAATTGAACGTGGCATGAATACTGAGGGCGTGCTGCCGGGGCCGCTGAACGTTCCACGCCGCGCG
GTAGCGTTACGGCGTCTGCTGGTCTCCAGCGATAATCTCTCCCGCGATCCAATGAACGTCATCGACTGGATTAACATGTT
CGCCCTGGCCGTGAGCGAAGAGAACGCGGCGGGCGGGCGAGTGGTCACCGCGCCGACCAACGGCGCGTGCGGCATTATTC
CTGCGGTGCTGGCCTATTACGACAAATTCCGTCGTCCGGTCAATGCCAACTCTATCGCCCGTTATCTGTTGTCGGCGGGG
GCGATTGGCATGCTGTACAAGATGAACGCCTCGATATCCGGCGCGGAAGTGGGGTGTCAGGGCGAGGTTGGCGTCGCGTG
TTCGATGGCGGCGGCGGGGCTGACAGAACTGCTGGGCGGTAGCCCGGCGCAGGTCTGTATTGCGGCGGAAATTGCGATGG
AGCATAACCTTGGCCTCACCTGTGACCCGGTGGCGGGTCAGGTACAAATCCCTTGTATTGAACGTAATGCGATTAACGCC
GTTAAAGCGGTAAATGCGGCGCGAATGGCGCTACGCCGTACCTCTGAGCCGCGGGTTTCGCTCGATAAAGTGATCGAAAC
CATGTACGAAACGGGTAAAGACATGAACGACAAATATCGCGAGACGTCGCGCGGCGGTCTGGCGATTAAAGTCGTTTGTG
GATAG

Upstream 100 bases:

>100_bases
TATTTCGCGCACCTTTACTCAGGCGATGTAACGTGAACGGGGCGATCGTGTGGATCGTCCCGCGACGGATCTTCACTGAA
CGGTAATCTTAGGGGGAGAT

Downstream 100 bases:

>100_bases
GCCCGACAGGCGCAGAGTGAGCAGGCTATGGGATAACGCAGAAGACAGAAGCTGAGAAAAGGGCGCACCAGTGTGCGCCC
TTTTTTGTTGTGATGTGCGT

Product: L-serine ammonia-lyase

Products: NA

Alternate protein names: SDH; L-serine deaminase [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MISAFDIFKIGIGPSSSHTVGPMNAGKCFIDRLNDSGDLPRTTRITVDLYGSLSLTGKGHATDTAIIMGLAGNTPQDVNI
DSIPAFIQEVVRSSRLSVAGGAHVVDFPVADSILFHAETLARHENGMRITAWNGQTPLLHKTYYSIGGGFIVEEERFGQS
HDVEKSVPYDFHSASELLTLCERQGLSVSGLMMQNELALRSKEQIDAGFARIWQVMETGIERGMNTEGVLPGPLNVPRRA
VALRRLLVSSDNLSRDPMNVIDWINMFALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNANSIARYLLSAG
AIGMLYKMNASISGAEVGCQGEVGVACSMAAAGLTELLGGSPAQVCIAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINA
VKAVNAARMALRRTSEPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG

Sequences:

>Translated_454_residues
MISAFDIFKIGIGPSSSHTVGPMNAGKCFIDRLNDSGDLPRTTRITVDLYGSLSLTGKGHATDTAIIMGLAGNTPQDVNI
DSIPAFIQEVVRSSRLSVAGGAHVVDFPVADSILFHAETLARHENGMRITAWNGQTPLLHKTYYSIGGGFIVEEERFGQS
HDVEKSVPYDFHSASELLTLCERQGLSVSGLMMQNELALRSKEQIDAGFARIWQVMETGIERGMNTEGVLPGPLNVPRRA
VALRRLLVSSDNLSRDPMNVIDWINMFALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNANSIARYLLSAG
AIGMLYKMNASISGAEVGCQGEVGVACSMAAAGLTELLGGSPAQVCIAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINA
VKAVNAARMALRRTSEPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
>Mature_454_residues
MISAFDIFKIGIGPSSSHTVGPMNAGKCFIDRLNDSGDLPRTTRITVDLYGSLSLTGKGHATDTAIIMGLAGNTPQDVNI
DSIPAFIQEVVRSSRLSVAGGAHVVDFPVADSILFHAETLARHENGMRITAWNGQTPLLHKTYYSIGGGFIVEEERFGQS
HDVEKSVPYDFHSASELLTLCERQGLSVSGLMMQNELALRSKEQIDAGFARIWQVMETGIERGMNTEGVLPGPLNVPRRA
VALRRLLVSSDNLSRDPMNVIDWINMFALAVSEENAAGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNANSIARYLLSAG
AIGMLYKMNASISGAEVGCQGEVGVACSMAAAGLTELLGGSPAQVCIAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINA
VKAVNAARMALRRTSEPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI48994925, Length=454, Percent_Identity=87.0044052863436, Blast_Score=813, Evalue=0.0,
Organism=Escherichia coli, GI1789161, Length=452, Percent_Identity=74.7787610619469, Blast_Score=686, Evalue=0.0,
Organism=Escherichia coli, GI1788116, Length=453, Percent_Identity=73.9514348785872, Blast_Score=684, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48572; Mature: 48572

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.7 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MISAFDIFKIGIGPSSSHTVGPMNAGKCFIDRLNDSGDLPRTTRITVDLYGSLSLTGKGH
CCCCEEEEEEECCCCCCCCCCCCCCCCHHHEECCCCCCCCCEEEEEEEEEEEEEECCCCC
ATDTAIIMGLAGNTPQDVNIDSIPAFIQEVVRSSRLSVAGGAHVVDFPVADSILFHAETL
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCHHHHHHHHHHH
ARHENGMRITAWNGQTPLLHKTYYSIGGGFIVEEERFGQSHDVEKSVPYDFHSASELLTL
HHCCCCCEEEEECCCCCCHHHHHHHCCCCEEEEHHHCCCCCCCCCCCCCCCCCHHHHHHH
CERQGLSVSGLMMQNELALRSKEQIDAGFARIWQVMETGIERGMNTEGVLPGPLNVPRRA
HHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VALRRLLVSSDNLSRDPMNVIDWINMFALAVSEENAAGGRVVTAPTNGACGIIPAVLAYY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DKFRRPVNANSIARYLLSAGAIGMLYKMNASISGAEVGCQGEVGVACSMAAAGLTELLGG
HHHCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPAQVCIAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMALRRTSEPRVS
CCHHEEEEEEHHHHCCCCCEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCHH
LDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
HHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEC
>Mature Secondary Structure
MISAFDIFKIGIGPSSSHTVGPMNAGKCFIDRLNDSGDLPRTTRITVDLYGSLSLTGKGH
CCCCEEEEEEECCCCCCCCCCCCCCCCHHHEECCCCCCCCCEEEEEEEEEEEEEECCCCC
ATDTAIIMGLAGNTPQDVNIDSIPAFIQEVVRSSRLSVAGGAHVVDFPVADSILFHAETL
CCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEECCCCEEEECCCHHHHHHHHHHH
ARHENGMRITAWNGQTPLLHKTYYSIGGGFIVEEERFGQSHDVEKSVPYDFHSASELLTL
HHCCCCCEEEEECCCCCCHHHHHHHCCCCEEEEHHHCCCCCCCCCCCCCCCCCHHHHHHH
CERQGLSVSGLMMQNELALRSKEQIDAGFARIWQVMETGIERGMNTEGVLPGPLNVPRRA
HHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHH
VALRRLLVSSDNLSRDPMNVIDWINMFALAVSEENAAGGRVVTAPTNGACGIIPAVLAYY
HHHHHHHHCCCCCCCCHHHHHHHHHHHHEEECCCCCCCCEEEECCCCCCCHHHHHHHHHH
DKFRRPVNANSIARYLLSAGAIGMLYKMNASISGAEVGCQGEVGVACSMAAAGLTELLGG
HHHCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCC
SPAQVCIAAEIAMEHNLGLTCDPVAGQVQIPCIERNAINAVKAVNAARMALRRTSEPRVS
CCHHEEEEEEHHHHCCCCCEECCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCHH
LDKVIETMYETGKDMNDKYRETSRGGLAIKVVCG
HHHHHHHHHHCCCCCCHHHHHHCCCCEEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9278503; 9484901 [H]