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The map label for this gene is ccmE1 [H]

Identifier: 194736683

GI number: 194736683

Start: 2356693

End: 2357172

Strand: Reverse

Name: ccmE1 [H]

Synonym: SeSA_A2476

Alternate gene names: 194736683

Gene position: 2357172-2356693 (Counterclockwise)

Preceding gene: 194734401

Following gene: 194737150

Centisome position: 50.06

GC content: 66.25

Gene sequence:

>480_bases
GTGAACCTGCGACGTAAAAACCGGCTATGGGTGGTCTGCGCGGTGCTGGCGGGCCTGGGGCTGACCACCGCCCTGGTCCT
GTACGCGCTGCGCGCGAATATCGACCTGTTCTATACCCCCGGCGAAATTCTCTACGGCAAGCGCGAGACGCAGCAGCTGC
CGGCGGCGGGCCAGCGCCTGCGCGTCGGCGGGATGGTGATGCCCGGCAGCGTCAGGCGCGCCCCGGACTCGCTGAAGGTG
AACTTCAGCCTCTACGACGCCGAAGGGGCGGTGACGGTGAGCTATGAGGGGATACTGCCGGACCTGTTCCGCGAGGGGCA
GGGGGTGGTGGTGCAGGGCACCCTGGAGAAGGGCAACCACGTCCTGGCGCAGGAGGTGCTGGCCAAGCATGACGAGAACT
ACACCCCGCCGGAAGTGGAAAAGGCGATGCAGGAAAACCACCGCCGCCCGCAACGCGCTGATAAGGACACCTCATCATGA

Upstream 100 bases:

>100_bases
TGCACACGGTGCTGCAGCGCCGGGCCATTCTGCGCGGCGTGGCGCAGCAGCGGGCGCGCGAGGCGCGGATGCGTGCCGCA
CAGGCGCAACAGGAGGCGGC

Downstream 100 bases:

>100_bases
TGCCTGAATACGGCCACGCGCTGCTGTGCCTGGCGCTCGGCGTGGCGCTGCTGCTGTCCGTTTACCCGCTGTGGGGCGTG
GCGCGCGGCGACGCGCGGAT

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E 1; Heme chaperone CcmE 1 [H]

Number of amino acids: Translated: 159; Mature: 159

Protein sequence:

>159_residues
MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAAGQRLRVGGMVMPGSVRRAPDSLKV
NFSLYDAEGAVTVSYEGILPDLFREGQGVVVQGTLEKGNHVLAQEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS

Sequences:

>Translated_159_residues
MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAAGQRLRVGGMVMPGSVRRAPDSLKV
NFSLYDAEGAVTVSYEGILPDLFREGQGVVVQGTLEKGNHVLAQEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS
>Mature_159_residues
MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAAGQRLRVGGMVMPGSVRRAPDSLKV
NFSLYDAEGAVTVSYEGILPDLFREGQGVVVQGTLEKGNHVLAQEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=159, Percent_Identity=81.7610062893082, Blast_Score=279, Evalue=8e-77,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 17619; Mature: 17619

Theoretical pI: Translated: 8.99; Mature: 8.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAAGQRL
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCHHEECCCHHHHCCCCCCEE
RVGGMVMPGSVRRAPDSLKVNFSLYDAEGAVTVSYEGILPDLFREGQGVVVQGTLEKGNH
EECCEECCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCHHHHHCCCCEEEEEECCCCCC
VLAQEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MNLRRKNRLWVVCAVLAGLGLTTALVLYALRANIDLFYTPGEILYGKRETQQLPAAGQRL
CCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEECCCHHEECCCHHHHCCCCCCEE
RVGGMVMPGSVRRAPDSLKVNFSLYDAEGAVTVSYEGILPDLFREGQGVVVQGTLEKGNH
EECCEECCCCCCCCCCCEEEEEEEEECCCEEEEEECCCCHHHHHCCCCEEEEEECCCCCC
VLAQEVLAKHDENYTPPEVEKAMQENHRRPQRADKDTSS
HHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA