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The map label for this gene is cirA [H]

Identifier: 194735726

GI number: 194735726

Start: 2317018

End: 2318970

Strand: Reverse

Name: cirA [H]

Synonym: SeSA_A2438

Alternate gene names: 194735726

Gene position: 2318970-2317018 (Counterclockwise)

Preceding gene: 194735104

Following gene: 194737592

Centisome position: 49.24

GC content: 54.63

Gene sequence:

>1953_bases
ATGTCCGCAGTTACGTTGGCCTGGCCGGTTGCCGCGGCAACGGATGATGGTGAAACCATGGTCGTTACCGCGTCCGCTAT
TGAACAAAATCTGAAAGATGCGCCAGCAAGTATCAGCGTCATTACCCAGCAAGATTTACAGCGCAGGCCCGTGCAAAACC
TGAAAGATGTCCTGAAAGAGGTGCCGGGCGTACAGCTCACTAACGAAGGGGATAACCGTAAAGGCGTGAGTATTCGTGGT
CTGGACAGCAGTTATACGCTGATCCTGATCGACGGTAAGCGCGTTAACTCCCGTAACGCGGTCTTCCGCCATAATGATTT
TGATCTGAACTGGATACCGGTTGACGCTATCGAACGCATTGAAGTGGTGCGTGGCCCCATGTCCTCGCTGTATGGCTCCG
ATGCGCTGGGCGGCGTGGTCAACATTATTACCAAAAAAATTGGTCAGAAATGGCACGGTAGCGTCACGGTTGACTCCACT
ATTCAGGAACATCGCGACCGTGGCGATACCTATAACGGCCAGTTCTTTACCAGCGGTCCGCTGATCGACGGCGTGCTGGG
AATGAAAGCCTACGGTAGCCTGGCGAAACGCGGAAAAGACGAGCAGCAGAGTTCCGCCACCACCGCTACGGGTGAAACGC
CGCGCATTGAAGGATTTACCAGCCGGGATGGAAACGTCGAGTTTGCCTGGACACCAAACGAAAATCATGACGTTACCGCA
GGCTACGGTTTTGATCGCCAGGACCGGGACTCCGACTCGCTGGATAAAAACCGTCTGGAACGGCAAAACTACGCGTTGAG
CCATAACGGACGTTGGGATCTCGGTAACAGCGAGCTCAAGTTCTACGGCGAAAAAGTGGAAAACAAAAACCCCGGCAACA
GTAGCCCTATCACGTCAGAAAGCAATTCGATTGACGGGAAATACGTTCTGCCGTTAGCGTCTGTCAACCAGTTCCTCACC
TTCGGCGGCGAATGGCGTCACGATAAACTGAGCGATGCGGTCAACCTGACCGGCGGTTCCAGTACTAAAACCTCCGCCAG
CCAGTATGCTCTGTTCCTTGAAGATGAGTGGCGCATCTTCGAACCGCTGGCGCTGACCACCGGTATTCGTATGGATGACC
ATGAAACCTATGGCGATCACTGGAGCCCGCGTGCTTATCTGGTCTATAACGCAACGGATACCCTGACGGTGAAAGGTGGG
TGGGCCACGGCCTTTAAAGCGCCGTCGCTATTGCAATTAAGTCCGGACTGGGCGACCAACTCCTGCCGTGGAGGATGCCG
CATTATCGGTAGCCCGGATCTGAAACCTGAAACCAGTGAAAGCTGGGAGCTCGGCCTTTACTACCGTGGCGAAGAAGGCA
TACTGGAGGGCGTGGAAGCGAGCGTTACCACGTTCCGTAACGATGTGGACAATCGCATCAGCATTAGCCGTACCGCTGAC
GTTAACGCCGCGCCCGGCTATTCCAACTTTGTCGGTTTCGAAACCAATAGTCGGGGACAGCGCGTTCCGGTCTTCCGTTA
TTACAACGTGAATAAAGCGCGTATTCAGGGCGTGGAAACCGAGTTGAAAGTTCCGTTTAACGAGGCGTGGAAACTGTCGT
TGAATTACACCTATAACGACGGACGCGACGTCAGTAATGGCGGGAACAAGCCGCTTTCCGATCTGCCGTTCCACACCGCG
AACGGTACGCTGGACTGGAAACCGGTGCAGCTCGAAGACTGGTCATTCTACGTATCAGGGAATTATACCGGGCGTAAGCG
GGCCGACAGCGCAACGGCGAAAACGCCGGGTGGGTACGTGGTCTGGGATACCGGCGCGGCATGGCAGGCGACGAAAAATG
TTAAACTGCGTGCGGGCGTTCTGAACGTGGGCGATAAAGATCTCAAACGCGACGACTACGGTTACACCGAAGACGGACGT
CGTTACTTTATGGCGGTGGATTACCGTTTCTGA

Upstream 100 bases:

>100_bases
ACGTAATGCGTTGTGAGCGATAACCGATTTTTTTGTCGTATTTACCTCATGGAGAAATGGAATGTTTAGGTTTAACCCTT
TCGTTCGGGTAGGGCTTTGT

Downstream 100 bases:

>100_bases
CAGAGACTGGCGACAGCCGCGTTTTGCCGCTGTCGCCAGAATGTTATAACCGATGCAGCCTGGAGAGCAGCGCCAGCGAC
AGAGTCGTTAACAGAATGGC

Product: colicin I receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 650; Mature: 649

Protein sequence:

>650_residues
MSAVTLAWPVAAATDDGETMVVTASAIEQNLKDAPASISVITQQDLQRRPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRG
LDSSYTLILIDGKRVNSRNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQKWHGSVTVDST
IQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKRGKDEQQSSATTATGETPRIEGFTSRDGNVEFAWTPNENHDVTA
GYGFDRQDRDSDSLDKNRLERQNYALSHNGRWDLGNSELKFYGEKVENKNPGNSSPITSESNSIDGKYVLPLASVNQFLT
FGGEWRHDKLSDAVNLTGGSSTKTSASQYALFLEDEWRIFEPLALTTGIRMDDHETYGDHWSPRAYLVYNATDTLTVKGG
WATAFKAPSLLQLSPDWATNSCRGGCRIIGSPDLKPETSESWELGLYYRGEEGILEGVEASVTTFRNDVDNRISISRTAD
VNAAPGYSNFVGFETNSRGQRVPVFRYYNVNKARIQGVETELKVPFNEAWKLSLNYTYNDGRDVSNGGNKPLSDLPFHTA
NGTLDWKPVQLEDWSFYVSGNYTGRKRADSATAKTPGGYVVWDTGAAWQATKNVKLRAGVLNVGDKDLKRDDYGYTEDGR
RYFMAVDYRF

Sequences:

>Translated_650_residues
MSAVTLAWPVAAATDDGETMVVTASAIEQNLKDAPASISVITQQDLQRRPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRG
LDSSYTLILIDGKRVNSRNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQKWHGSVTVDST
IQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKRGKDEQQSSATTATGETPRIEGFTSRDGNVEFAWTPNENHDVTA
GYGFDRQDRDSDSLDKNRLERQNYALSHNGRWDLGNSELKFYGEKVENKNPGNSSPITSESNSIDGKYVLPLASVNQFLT
FGGEWRHDKLSDAVNLTGGSSTKTSASQYALFLEDEWRIFEPLALTTGIRMDDHETYGDHWSPRAYLVYNATDTLTVKGG
WATAFKAPSLLQLSPDWATNSCRGGCRIIGSPDLKPETSESWELGLYYRGEEGILEGVEASVTTFRNDVDNRISISRTAD
VNAAPGYSNFVGFETNSRGQRVPVFRYYNVNKARIQGVETELKVPFNEAWKLSLNYTYNDGRDVSNGGNKPLSDLPFHTA
NGTLDWKPVQLEDWSFYVSGNYTGRKRADSATAKTPGGYVVWDTGAAWQATKNVKLRAGVLNVGDKDLKRDDYGYTEDGR
RYFMAVDYRF
>Mature_649_residues
SAVTLAWPVAAATDDGETMVVTASAIEQNLKDAPASISVITQQDLQRRPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGL
DSSYTLILIDGKRVNSRNAVFRHNDFDLNWIPVDAIERIEVVRGPMSSLYGSDALGGVVNIITKKIGQKWHGSVTVDSTI
QEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKRGKDEQQSSATTATGETPRIEGFTSRDGNVEFAWTPNENHDVTAG
YGFDRQDRDSDSLDKNRLERQNYALSHNGRWDLGNSELKFYGEKVENKNPGNSSPITSESNSIDGKYVLPLASVNQFLTF
GGEWRHDKLSDAVNLTGGSSTKTSASQYALFLEDEWRIFEPLALTTGIRMDDHETYGDHWSPRAYLVYNATDTLTVKGGW
ATAFKAPSLLQLSPDWATNSCRGGCRIIGSPDLKPETSESWELGLYYRGEEGILEGVEASVTTFRNDVDNRISISRTADV
NAAPGYSNFVGFETNSRGQRVPVFRYYNVNKARIQGVETELKVPFNEAWKLSLNYTYNDGRDVSNGGNKPLSDLPFHTAN
GTLDWKPVQLEDWSFYVSGNYTGRKRADSATAKTPGGYVVWDTGAAWQATKNVKLRAGVLNVGDKDLKRDDYGYTEDGRR
YFMAVDYRF

Specific function: Not yet known. Postulated to participate in iron transport. Outer membrane receptor for colicins IA and IB [H]

COG id: COG4771

COG function: function code P; Outer membrane receptor for ferrienterochelin and colicins

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1788478, Length=650, Percent_Identity=87.6923076923077, Blast_Score=1207, Evalue=0.0,
Organism=Escherichia coli, GI1786798, Length=755, Percent_Identity=32.1854304635762, Blast_Score=270, Evalue=2e-73,
Organism=Escherichia coli, GI1790405, Length=682, Percent_Identity=26.2463343108504, Blast_Score=161, Evalue=1e-40,
Organism=Escherichia coli, GI1787723, Length=154, Percent_Identity=31.1688311688312, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010916
- InterPro:   IPR010917 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 72060; Mature: 71929

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS00430 TONB_DEPENDENT_REC_1 ; PS01156 TONB_DEPENDENT_REC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVTLAWPVAAATDDGETMVVTASAIEQNLKDAPASISVITQQDLQRRPVQNLKDVLKE
CCEEEEEEEEEEECCCCCEEEEEHHHHHHHHHCCCCEEEEEEHHHHHHCCHHHHHHHHHH
VPGVQLTNEGDNRKGVSIRGLDSSYTLILIDGKRVNSRNAVFRHNDFDLNWIPVDAIERI
CCCEEEECCCCCCCCCEEEECCCCEEEEEEECCEECCCCCEEEECCCCCEEEEHHHHHHH
EVVRGPMSSLYGSDALGGVVNIITKKIGQKWHGSVTVDSTIQEHRDRGDTYNGQFFTSGP
HHHHCCHHHHCCCHHHHHHHHHHHHHHCHHHCCCEEEHHHHHHHHHCCCCCCCEEEECCC
LIDGVLGMKAYGSLAKRGKDEQQSSATTATGETPRIEGFTSRDGNVEFAWTPNENHDVTA
CHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCEEE
GYGFDRQDRDSDSLDKNRLERQNYALSHNGRWDLGNSELKFYGEKVENKNPGNSSPITSE
CCCCCCCCCCCCCHHHHHHHHHCEEECCCCEECCCCCCEEEEEHHHCCCCCCCCCCCCCC
SNSIDGKYVLPLASVNQFLTFGGEWRHDKLSDAVNLTGGSSTKTSASQYALFLEDEWRIF
CCCCCCEEEEEHHHHHHHHHCCCCCCCCHHCCEEEECCCCCCCCCCCEEEEEEECCCEEE
EPLALTTGIRMDDHETYGDHWSPRAYLVYNATDTLTVKGGWATAFKAPSLLQLSPDWATN
CCEEHHCCCEECCCCCCCCCCCCCEEEEEECCEEEEEECCEEEEECCCCEEEECCCCCCC
SCRGGCRIIGSPDLKPETSESWELGLYYRGEEGILEGVEASVTTFRNDVDNRISISRTAD
CCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCHHHCCHHHHHHHHHCCCCEEEEEEECC
VNAAPGYSNFVGFETNSRGQRVPVFRYYNVNKARIQGVETELKVPFNEAWKLSLNYTYND
CCCCCCCCCEEEEECCCCCCCCCEEEEECCCHHHEECCCEEEECCCCCEEEEEEEEEECC
GRDVSNGGNKPLSDLPFHTANGTLDWKPVQLEDWSFYVSGNYTGRKRADSATAKTPGGYV
CCCCCCCCCCCCCCCCEECCCCEECCEEEEEECEEEEEECCCCCCCCCCCCCCCCCCCEE
VWDTGAAWQATKNVKLRAGVLNVGDKDLKRDDYGYTEDGRRYFMAVDYRF
EECCCCCEEECCCEEEEEEEECCCCHHCCCCCCCCCCCCCEEEEEEEECC
>Mature Secondary Structure 
SAVTLAWPVAAATDDGETMVVTASAIEQNLKDAPASISVITQQDLQRRPVQNLKDVLKE
CEEEEEEEEEEECCCCCEEEEEHHHHHHHHHCCCCEEEEEEHHHHHHCCHHHHHHHHHH
VPGVQLTNEGDNRKGVSIRGLDSSYTLILIDGKRVNSRNAVFRHNDFDLNWIPVDAIERI
CCCEEEECCCCCCCCCEEEECCCCEEEEEEECCEECCCCCEEEECCCCCEEEEHHHHHHH
EVVRGPMSSLYGSDALGGVVNIITKKIGQKWHGSVTVDSTIQEHRDRGDTYNGQFFTSGP
HHHHCCHHHHCCCHHHHHHHHHHHHHHCHHHCCCEEEHHHHHHHHHCCCCCCCEEEECCC
LIDGVLGMKAYGSLAKRGKDEQQSSATTATGETPRIEGFTSRDGNVEFAWTPNENHDVTA
CHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCEECCCCCEEEEECCCCCCCEEE
GYGFDRQDRDSDSLDKNRLERQNYALSHNGRWDLGNSELKFYGEKVENKNPGNSSPITSE
CCCCCCCCCCCCCHHHHHHHHHCEEECCCCEECCCCCCEEEEEHHHCCCCCCCCCCCCCC
SNSIDGKYVLPLASVNQFLTFGGEWRHDKLSDAVNLTGGSSTKTSASQYALFLEDEWRIF
CCCCCCEEEEEHHHHHHHHHCCCCCCCCHHCCEEEECCCCCCCCCCCEEEEEEECCCEEE
EPLALTTGIRMDDHETYGDHWSPRAYLVYNATDTLTVKGGWATAFKAPSLLQLSPDWATN
CCEEHHCCCEECCCCCCCCCCCCCEEEEEECCEEEEEECCEEEEECCCCEEEECCCCCCC
SCRGGCRIIGSPDLKPETSESWELGLYYRGEEGILEGVEASVTTFRNDVDNRISISRTAD
CCCCCEEEECCCCCCCCCCCCEEEEEEEECCCCHHHCCHHHHHHHHHCCCCEEEEEEECC
VNAAPGYSNFVGFETNSRGQRVPVFRYYNVNKARIQGVETELKVPFNEAWKLSLNYTYND
CCCCCCCCCEEEEECCCCCCCCCEEEEECCCHHHEECCCEEEECCCCCEEEEEEEEEECC
GRDVSNGGNKPLSDLPFHTANGTLDWKPVQLEDWSFYVSGNYTGRKRADSATAKTPGGYV
CCCCCCCCCCCCCCCCEECCCCEECCEEEEEECEEEEEECCCCCCCCCCCCCCCCCCCEE
VWDTGAAWQATKNVKLRAGVLNVGDKDLKRDDYGYTEDGRRYFMAVDYRF
EECCCCCEEECCCEEEEEEEECCCCHHCCCCCCCCCCCCCEEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2644220; 9278503; 3316180; 1315732; 2160948 [H]