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The map label for this gene is dinB [H]

Identifier: 194735550

GI number: 194735550

Start: 367998

End: 369053

Strand: Direct

Name: dinB [H]

Synonym: SeSA_A0362

Alternate gene names: 194735550

Gene position: 367998-369053 (Clockwise)

Preceding gene: 194737580

Following gene: 194736029

Centisome position: 7.81

GC content: 51.23

Gene sequence:

>1056_bases
ATGCGCAAAATCATACATGTTGATATGGACTGTTTTTTTGCCGCGGTAGAGATGCGTGATAATCCGGCGTTACGCGATAT
TCCCATTGCCATTGGCGGGAGTCGTGAGCGAAGAGGTGTTATCAGTACCGCCAACTATCCTGCGCGCCAGTTTGGCGTAC
GTAGCGCGATGCCGACCGCCATGGCGCTAAAGCTGTGCCCCCATCTCACCTTACTGCCTGGCCGCTTTGACGCCTATAAA
GAGGCTTCGCGGCATGTACGTGACATCTTTTCCCGCTACACTTCACTGATTGAACCGCTCTCGCTGGATGAAGCCTGGCT
GGATGTGACTGACAGCCCACACTGTTATGGATCGGCGACTCTGATCGCCAGGGAGATTCGTCAGACTATTTTCAATGAAC
TGCAACTCACCGCCTCCGCCGGCGTTGCGCCAGTGAAATTTCTGGCGAAGATCGCCTCCGATCTCAATAAACCGAACGGA
CAATATGTTATTACGCCAGCCGATGTACCCGACTTTCTTAAAACGTTGCCGTTAGCCAAAATTCCAGGCGTGGGGAAAGT
TTCCGCCGCCAAACTGGAAAATATGGGGTTAAGAACCTGCGGGGATATTCAACAGTGCGATCTGGCGATGCTTCTCAAAC
GCTTTGGTAAATTTGGCCGGGTATTATGGGAGCGTAGTCAGGGTATTGACGAGCGTGATGTTAACAGCGAAAGGCTGCGT
AAATCGGTAGGTGTTGAGCGTACTCTGGCGGAGGATATTCATGAATGGTCGGACTGCGAGGCTATTATTGAGCATTTATA
TCCGGAGCTGGAGCGTCGTCTGGCTATAGTGAAGCCCGATTTACTGATTGCCCGACAGGGCGTTAAATTAAAATTTAATG
ATTTTCAGCAAACCACTCAGGAACATGTCTGGCCGCAATTAAATAAAGAAGACTTAATTACCACCGCCCGTAAAACCTGG
AACGAGCGTCGCGGCGAGCGCGGCGTACGGCTGGTGGGGCTACACGTAACGCTGCTCGACCCTCAATTGGAACGACAGTT
GGTGTTAGGGTTATAA

Upstream 100 bases:

>100_bases
TCGTCGTCATACCTTCGAATATGTCGCATTTTTAACGCGAATGTATCTTTGCGCGCAATAAAACATACTGTACACTTAAA
CAGTATTGTGGGGGCGAGCG

Downstream 100 bases:

>100_bases
GTCAGGCCATTAAGATTTTATCACTATTACGATTGCGCCATCTAAATTTCAGTATTACTATACCCGCGTTTTCTCATTCT
CAATAACTGCAAAGGAGGTT

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 351; Mature: 351

Protein sequence:

>351_residues
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARQFGVRSAMPTAMALKLCPHLTLLPGRFDAYK
EASRHVRDIFSRYTSLIEPLSLDEAWLDVTDSPHCYGSATLIAREIRQTIFNELQLTASAGVAPVKFLAKIASDLNKPNG
QYVITPADVPDFLKTLPLAKIPGVGKVSAAKLENMGLRTCGDIQQCDLAMLLKRFGKFGRVLWERSQGIDERDVNSERLR
KSVGVERTLAEDIHEWSDCEAIIEHLYPELERRLAIVKPDLLIARQGVKLKFNDFQQTTQEHVWPQLNKEDLITTARKTW
NERRGERGVRLVGLHVTLLDPQLERQLVLGL

Sequences:

>Translated_351_residues
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARQFGVRSAMPTAMALKLCPHLTLLPGRFDAYK
EASRHVRDIFSRYTSLIEPLSLDEAWLDVTDSPHCYGSATLIAREIRQTIFNELQLTASAGVAPVKFLAKIASDLNKPNG
QYVITPADVPDFLKTLPLAKIPGVGKVSAAKLENMGLRTCGDIQQCDLAMLLKRFGKFGRVLWERSQGIDERDVNSERLR
KSVGVERTLAEDIHEWSDCEAIIEHLYPELERRLAIVKPDLLIARQGVKLKFNDFQQTTQEHVWPQLNKEDLITTARKTW
NERRGERGVRLVGLHVTLLDPQLERQLVLGL
>Mature_351_residues
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARQFGVRSAMPTAMALKLCPHLTLLPGRFDAYK
EASRHVRDIFSRYTSLIEPLSLDEAWLDVTDSPHCYGSATLIAREIRQTIFNELQLTASAGVAPVKFLAKIASDLNKPNG
QYVITPADVPDFLKTLPLAKIPGVGKVSAAKLENMGLRTCGDIQQCDLAMLLKRFGKFGRVLWERSQGIDERDVNSERLR
KSVGVERTLAEDIHEWSDCEAIIEHLYPELERRLAIVKPDLLIARQGVKLKFNDFQQTTQEHVWPQLNKEDLITTARKTW
NERRGERGVRLVGLHVTLLDPQLERQLVLGL

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=330, Percent_Identity=30.6060606060606, Blast_Score=166, Evalue=4e-41,
Organism=Homo sapiens, GI7705344, Length=355, Percent_Identity=32.9577464788732, Blast_Score=162, Evalue=5e-40,
Organism=Homo sapiens, GI7706681, Length=331, Percent_Identity=31.1178247734139, Blast_Score=156, Evalue=3e-38,
Organism=Homo sapiens, GI154350220, Length=251, Percent_Identity=32.2709163346614, Blast_Score=135, Evalue=6e-32,
Organism=Homo sapiens, GI5729982, Length=353, Percent_Identity=29.7450424929178, Blast_Score=115, Evalue=8e-26,
Organism=Escherichia coli, GI1786425, Length=351, Percent_Identity=90.8831908831909, Blast_Score=665, Evalue=0.0,
Organism=Escherichia coli, GI1787432, Length=216, Percent_Identity=25.462962962963, Blast_Score=74, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI193205700, Length=403, Percent_Identity=33.2506203473945, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI17537959, Length=286, Percent_Identity=28.3216783216783, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI193205702, Length=348, Percent_Identity=29.5977011494253, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI115534089, Length=163, Percent_Identity=35.5828220858896, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324921, Length=208, Percent_Identity=30.2884615384615, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19923006, Length=327, Percent_Identity=30.8868501529052, Blast_Score=165, Evalue=4e-41,
Organism=Drosophila melanogaster, GI21355641, Length=378, Percent_Identity=29.3650793650794, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24644984, Length=378, Percent_Identity=29.3650793650794, Blast_Score=118, Evalue=8e-27,
Organism=Drosophila melanogaster, GI24668444, Length=119, Percent_Identity=36.1344537815126, Blast_Score=77, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 39657; Mature: 39657

Theoretical pI: Translated: 8.58; Mature: 8.58

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARQFGVRSAMPTA
CCCEEEECHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEECCCCCHHHHHHHHCCHHH
MALKLCPHLTLLPGRFDAYKEASRHVRDIFSRYTSLIEPLSLDEAWLDVTDSPHCYGSAT
HHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHH
LIAREIRQTIFNELQLTASAGVAPVKFLAKIASDLNKPNGQYVITPADVPDFLKTLPLAK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHCCCCC
IPGVGKVSAAKLENMGLRTCGDIQQCDLAMLLKRFGKFGRVLWERSQGIDERDVNSERLR
CCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSVGVERTLAEDIHEWSDCEAIIEHLYPELERRLAIVKPDLLIARQGVKLKFNDFQQTTQ
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCEEEEHHHHHHHH
EHVWPQLNKEDLITTARKTWNERRGERGVRLVGLHVTLLDPQLERQLVLGL
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECHHHHHHHHCCC
>Mature Secondary Structure
MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTANYPARQFGVRSAMPTA
CCCEEEECHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCEECCCCCHHHHHHHHCCHHH
MALKLCPHLTLLPGRFDAYKEASRHVRDIFSRYTSLIEPLSLDEAWLDVTDSPHCYGSAT
HHHHHCCCCEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCCCCCHHH
LIAREIRQTIFNELQLTASAGVAPVKFLAKIASDLNKPNGQYVITPADVPDFLKTLPLAK
HHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCEEEECCCCHHHHHHCCCCC
IPGVGKVSAAKLENMGLRTCGDIQQCDLAMLLKRFGKFGRVLWERSQGIDERDVNSERLR
CCCCCCHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHH
KSVGVERTLAEDIHEWSDCEAIIEHLYPELERRLAIVKPDLLIARQGVKLKFNDFQQTTQ
HHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHEECCCCEEEEHHHHHHHH
EHVWPQLNKEDLITTARKTWNERRGERGVRLVGLHVTLLDPQLERQLVLGL
HHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEEEEEECHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA