Click here to switch to the map view.

The map label for this gene is rfbC [H]

Identifier: 194334561

GI number: 194334561

Start: 1920396

End: 1920983

Strand: Reverse

Name: rfbC [H]

Synonym: Paes_1759

Alternate gene names: 194334561

Gene position: 1920983-1920396 (Counterclockwise)

Preceding gene: 194334562

Following gene: 194334560

Centisome position: 76.44

GC content: 44.05

Gene sequence:

>588_bases
ATGAATGTTATTTCAACATTGATTCCTGATGTGTTGATATTTGAACCAAAAGTTTTTGGTGATGAGCGTGGTTATTTTTT
CGAGTCGTTTCGTCAGGATATTTTTGAGCAGCATGTTGGTCAGGTGAACTTTGTTCAGGATAACCAGTCGAAATCAAAGT
ATGGGGTGTTGCGTGGCTTGCACTTCCAGAAGCCGCCGTTTACTCAGTCAAAGCTTGTTCGGGTACTTGACGGCTGTGTG
ATCGATGTTGCTGTTGATATTCGCAAAGGGTCACCATGGTTCGGGCAGTATGTGACGGTAAAGCTTGACTCTGTGAAAAA
CAATATGCTTTGGGTGCCCCAAGGTTTTGCGCATGGGTTTGTTGTCCTGTCAGAGGATGCTGTTTTTGCCTACAAATGCG
ATAATTACTATGCGCCTGATTATGATGCCGGAATTAGATGGAACGATCCTGAGTTATCCATTGATTGGGCTATCCCTGTC
GCTGACATACAGGTATCACAGAAGGATGCTACTCAACCGCTGTTGGACGAGTCTTATCTGTTTTCCTATGAGAGCTTTAA
GAAAGAAGCTGTTTACCCCCAACGTTGA

Upstream 100 bases:

>100_bases
GATGAGTTTGTTCGAGCAAAAGCAGGAGCTTGTTGAAGTATAGATTTGTTCTGCTGTTTTTCCTTTCTTTTCCCTCATTT
CATTTTACTCTGTCATTTCT

Downstream 100 bases:

>100_bases
TGGATGATTTATTTATGAAAAATATTCTTGTTACAGGCGGAGCCGGGTTTATCGGGTCACATGTGGTGCGGCGGTTTGTC
AATGCGTATCCGGAGTACCG

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 195; Mature: 195

Protein sequence:

>195_residues
MNVISTLIPDVLIFEPKVFGDERGYFFESFRQDIFEQHVGQVNFVQDNQSKSKYGVLRGLHFQKPPFTQSKLVRVLDGCV
IDVAVDIRKGSPWFGQYVTVKLDSVKNNMLWVPQGFAHGFVVLSEDAVFAYKCDNYYAPDYDAGIRWNDPELSIDWAIPV
ADIQVSQKDATQPLLDESYLFSYESFKKEAVYPQR

Sequences:

>Translated_195_residues
MNVISTLIPDVLIFEPKVFGDERGYFFESFRQDIFEQHVGQVNFVQDNQSKSKYGVLRGLHFQKPPFTQSKLVRVLDGCV
IDVAVDIRKGSPWFGQYVTVKLDSVKNNMLWVPQGFAHGFVVLSEDAVFAYKCDNYYAPDYDAGIRWNDPELSIDWAIPV
ADIQVSQKDATQPLLDESYLFSYESFKKEAVYPQR
>Mature_195_residues
MNVISTLIPDVLIFEPKVFGDERGYFFESFRQDIFEQHVGQVNFVQDNQSKSKYGVLRGLHFQKPPFTQSKLVRVLDGCV
IDVAVDIRKGSPWFGQYVTVKLDSVKNNMLWVPQGFAHGFVVLSEDAVFAYKCDNYYAPDYDAGIRWNDPELSIDWAIPV
ADIQVSQKDATQPLLDESYLFSYESFKKEAVYPQR

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=178, Percent_Identity=54.4943820224719, Blast_Score=186, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI17550412, Length=168, Percent_Identity=44.6428571428571, Blast_Score=129, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 22424; Mature: 22424

Theoretical pI: Translated: 4.72; Mature: 4.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVISTLIPDVLIFEPKVFGDERGYFFESFRQDIFEQHVGQVNFVQDNQSKSKYGVLRGL
CCHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHCC
HFQKPPFTQSKLVRVLDGCVIDVAVDIRKGSPWFGQYVTVKLDSVKNNMLWVPQGFAHGF
CCCCCCCCHHHHHHHHCCEEEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCCCEE
VVLSEDAVFAYKCDNYYAPDYDAGIRWNDPELSIDWAIPVADIQVSQKDATQPLLDESYL
EEEECCEEEEEECCCEECCCCCCCCEECCCCEEEEEEEEEEEEEECCCCCCCCCCCHHHH
FSYESFKKEAVYPQR
HHHHHHHHCCCCCCC
>Mature Secondary Structure
MNVISTLIPDVLIFEPKVFGDERGYFFESFRQDIFEQHVGQVNFVQDNQSKSKYGVLRGL
CCHHHHHCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHCCEEEEEECCCCCCHHHHHHCC
HFQKPPFTQSKLVRVLDGCVIDVAVDIRKGSPWFGQYVTVKLDSVKNNMLWVPQGFAHGF
CCCCCCCCHHHHHHHHCCEEEEEEEEEECCCCCCCCEEEEEEECCCCCEEEEECCCCCEE
VVLSEDAVFAYKCDNYYAPDYDAGIRWNDPELSIDWAIPVADIQVSQKDATQPLLDESYL
EEEECCEEEEEECCCEECCCCCCCCEECCCCEEEEEEEEEEEEEECCCCCCCCCCCHHHH
FSYESFKKEAVYPQR
HHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609; 10802738 [H]