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The map label for this gene is fusA [H]

Identifier: 193213533

GI number: 193213533

Start: 2088736

End: 2090814

Strand: Direct

Name: fusA [H]

Synonym: Cpar_1894

Alternate gene names: 193213533

Gene position: 2088736-2090814 (Clockwise)

Preceding gene: 193213520

Following gene: 193213537

Centisome position: 91.24

GC content: 55.03

Gene sequence:

>2079_bases
ATGCAAGCTGTTCCAACCGACCAATTGAGGAACATTGTCGTTACCGGCCATTCCGGAACCGGAAAAACCATGCTGTGCGA
ATCGCTTGCCCTGAGCATGGGGATAATCAACCGGCTCGGCAGCATTGAAGAAGGGACGACCCTGTCAGATTATGCATCCG
ATGAAATCGAAAGAAAACACAGCCTGAACACCAGCCTCATTCACGGAAACTGGAAAGACAAGAAGATCAATATCATCGAC
ACTCCCGGCCTGCTCGACTTTCACGGGGACGTCAAATCGGCTATGCGCGTGGCCGATACGGTGCTGATCACAGTCAACGC
AGCCACGGGCGTTGAGGTAGGCACCGACACCGTCTGGGACTATACGCAGGAGTACTACAAACCGACCGTGTTCGTGCTGA
CCAAGCTCGATGCCGATCGGGCTGACTTCGACACAACCCTCGAAGCTCTGCGCGACCATTTCGGCCATCTGGTCACGCCG
ATCCAGTTCCCAGTAGAAGAAGGCCAGAATCACCACATTCTGATTGACGTGCTGCTGATGAAGCAGCTTGAATTCAATCC
CGACAAGCCGGGCAGCATGGAAATTTCCGAGATTCCCGACCTCTACCGGAAAAAGGCCGAGGAGCTTCACCAGCAACTGG
TCGAGGCAGTCGCCGAAACCGACGAGGAGCTCATGAACCGCTTTTTCGACGTCGGCACCCTGGCTGAAGACGAGCTCCGG
GCTGGCATCAAATCGGCGCTCGTGACGCGAACCTTCTTCCCGGTTTTCTGTACCTCCCCGCTTCATCTGATCGGTTCGGA
GCGCCTGCTCAACGCCATCGTTAACCTCTGCCCTTCGCCGATCGAGCGCGGCCCGGAACACGCCTACTGTTCGGTGATGA
ACGACGAAAAGCTGCTCGATCCCGACCCGGAAGGCCCGACGGTCGCATTCATCTTCAAGACCATGTCGGAACCGAGAGTT
GGCGAAATCTCCTATGTACGCGTCTATTCCGGCCACATTGAAACCGGACATGAACTGATCGACGCCCAGACCGGGCAGCT
CGAAAAGCTCGGACAGGTCTATACCATGCTTGGACAGAAAAAAATCCCGGTCGACAAGCTCCTTGCCGGCGACATCGGCA
TGGTGGTCAAGCTCAAAAACTCCCACACCAACGACACGTTGGCCGACAAAGGAGTCGATTGCCGCATCAGCCCGATCATC
TTCCCCGAACCGGTGCTTTCCACAGCTATCGTTCCGACCACCCAGGGTGATGAGGAAAAGATTTCATCCGGTCTGCACCA
CCTCCACGAAGAGGATCCGAGCTTTACCATCGAGCACGATACGGAGTTCAACCAGACCATTCTGAAAACCCTCGGAGAAA
CCCATCTCGACATCATCATCAGCCGTCTGTTCAACAAGTTCAACGTAAAAGTCGAGACCGCCCCCATCCGCATTCCCTAT
CGCGAAACCATCAGAATCAGCGCCTCGGCGCAGGGCAAATTCAAAAAGCAGTCGGGTGGCCGTGGCCAGTATGGTGATGT
GTGGATCAGGATCGAGCCTACGGAACGAGACTCTGGATTCGAGTTCGCCAGCGAAGTGGTTGGCGGCGTAGTGCCAACCC
GCTATTTACCGGCTGTCGAAAAGGGAATACGCGAAACGATCACTCATGGACTCCTTGCCGGCTATCCACTGGTCGATCTC
AAGGCCGTAGCCTACGATGGTTCGCACCATCCGGTTGACAGCTCGGAGAACGCTTTTAAAATCGCGGCAAGCATGGGCTT
CAAAGCCGCCTTTGACAAAGCAAAACCACTGATTCTCGAACCGCTCTGTTCACTCACCGTTCAGACACCTGACCAGTATA
CCGGTGAAATCGTCGGGGAAATCTCAAGCAAGCGAGGCCGTATTCTCGGCATGGATACCGACTCACGATTCCAGATCATC
AAGGCGATGATTCCGCAAGCCTCGCTCTCGGATTTCCATCATGCGCTGACCAGGCTGACCCATAGCCGAGCCCGATACAG
CTACACGTTCAGCCATTACGAAGAGGCTCCATCCGATGTAGCAAGCAAGCTCATTGCGGAGAAAAACAACGAAAGCTAA

Upstream 100 bases:

>100_bases
AGTGCCGCAGGCTGAATTCCCTGCAAAGACCGTCGTGAAGCAGTAATCTCCGGCCACAGCGGACCGCTCCGTTCAACCAA
ACCAATAAAGGAGTACTGAC

Downstream 100 bases:

>100_bases
AGGCTTTCTTCTCAAGCGAGTAGACTTAATCAAACTTGTCAAAACAAAAGCGGCTGTACAATCATCGAGTACAGCCGCTT
TTGTTTTGTTCTGATATAGC

Product: elongation factor G

Products: GDP; phosphate

Alternate protein names: EF-G [H]

Number of amino acids: Translated: 692; Mature: 692

Protein sequence:

>692_residues
MQAVPTDQLRNIVVTGHSGTGKTMLCESLALSMGIINRLGSIEEGTTLSDYASDEIERKHSLNTSLIHGNWKDKKINIID
TPGLLDFHGDVKSAMRVADTVLITVNAATGVEVGTDTVWDYTQEYYKPTVFVLTKLDADRADFDTTLEALRDHFGHLVTP
IQFPVEEGQNHHILIDVLLMKQLEFNPDKPGSMEISEIPDLYRKKAEELHQQLVEAVAETDEELMNRFFDVGTLAEDELR
AGIKSALVTRTFFPVFCTSPLHLIGSERLLNAIVNLCPSPIERGPEHAYCSVMNDEKLLDPDPEGPTVAFIFKTMSEPRV
GEISYVRVYSGHIETGHELIDAQTGQLEKLGQVYTMLGQKKIPVDKLLAGDIGMVVKLKNSHTNDTLADKGVDCRISPII
FPEPVLSTAIVPTTQGDEEKISSGLHHLHEEDPSFTIEHDTEFNQTILKTLGETHLDIIISRLFNKFNVKVETAPIRIPY
RETIRISASAQGKFKKQSGGRGQYGDVWIRIEPTERDSGFEFASEVVGGVVPTRYLPAVEKGIRETITHGLLAGYPLVDL
KAVAYDGSHHPVDSSENAFKIAASMGFKAAFDKAKPLILEPLCSLTVQTPDQYTGEIVGEISSKRGRILGMDTDSRFQII
KAMIPQASLSDFHHALTRLTHSRARYSYTFSHYEEAPSDVASKLIAEKNNES

Sequences:

>Translated_692_residues
MQAVPTDQLRNIVVTGHSGTGKTMLCESLALSMGIINRLGSIEEGTTLSDYASDEIERKHSLNTSLIHGNWKDKKINIID
TPGLLDFHGDVKSAMRVADTVLITVNAATGVEVGTDTVWDYTQEYYKPTVFVLTKLDADRADFDTTLEALRDHFGHLVTP
IQFPVEEGQNHHILIDVLLMKQLEFNPDKPGSMEISEIPDLYRKKAEELHQQLVEAVAETDEELMNRFFDVGTLAEDELR
AGIKSALVTRTFFPVFCTSPLHLIGSERLLNAIVNLCPSPIERGPEHAYCSVMNDEKLLDPDPEGPTVAFIFKTMSEPRV
GEISYVRVYSGHIETGHELIDAQTGQLEKLGQVYTMLGQKKIPVDKLLAGDIGMVVKLKNSHTNDTLADKGVDCRISPII
FPEPVLSTAIVPTTQGDEEKISSGLHHLHEEDPSFTIEHDTEFNQTILKTLGETHLDIIISRLFNKFNVKVETAPIRIPY
RETIRISASAQGKFKKQSGGRGQYGDVWIRIEPTERDSGFEFASEVVGGVVPTRYLPAVEKGIRETITHGLLAGYPLVDL
KAVAYDGSHHPVDSSENAFKIAASMGFKAAFDKAKPLILEPLCSLTVQTPDQYTGEIVGEISSKRGRILGMDTDSRFQII
KAMIPQASLSDFHHALTRLTHSRARYSYTFSHYEEAPSDVASKLIAEKNNES
>Mature_692_residues
MQAVPTDQLRNIVVTGHSGTGKTMLCESLALSMGIINRLGSIEEGTTLSDYASDEIERKHSLNTSLIHGNWKDKKINIID
TPGLLDFHGDVKSAMRVADTVLITVNAATGVEVGTDTVWDYTQEYYKPTVFVLTKLDADRADFDTTLEALRDHFGHLVTP
IQFPVEEGQNHHILIDVLLMKQLEFNPDKPGSMEISEIPDLYRKKAEELHQQLVEAVAETDEELMNRFFDVGTLAEDELR
AGIKSALVTRTFFPVFCTSPLHLIGSERLLNAIVNLCPSPIERGPEHAYCSVMNDEKLLDPDPEGPTVAFIFKTMSEPRV
GEISYVRVYSGHIETGHELIDAQTGQLEKLGQVYTMLGQKKIPVDKLLAGDIGMVVKLKNSHTNDTLADKGVDCRISPII
FPEPVLSTAIVPTTQGDEEKISSGLHHLHEEDPSFTIEHDTEFNQTILKTLGETHLDIIISRLFNKFNVKVETAPIRIPY
RETIRISASAQGKFKKQSGGRGQYGDVWIRIEPTERDSGFEFASEVVGGVVPTRYLPAVEKGIRETITHGLLAGYPLVDL
KAVAYDGSHHPVDSSENAFKIAASMGFKAAFDKAKPLILEPLCSLTVQTPDQYTGEIVGEISSKRGRILGMDTDSRFQII
KAMIPQASLSDFHHALTRLTHSRARYSYTFSHYEEAPSDVASKLIAEKNNES

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=684, Percent_Identity=30.4093567251462, Blast_Score=324, Evalue=2e-88,
Organism=Homo sapiens, GI19923640, Length=710, Percent_Identity=25.2112676056338, Blast_Score=247, Evalue=3e-65,
Organism=Homo sapiens, GI25306287, Length=688, Percent_Identity=25, Blast_Score=203, Evalue=3e-52,
Organism=Homo sapiens, GI25306283, Length=394, Percent_Identity=26.6497461928934, Blast_Score=152, Evalue=1e-36,
Organism=Escherichia coli, GI1789738, Length=700, Percent_Identity=34.8571428571429, Blast_Score=447, Evalue=1e-126,
Organism=Escherichia coli, GI1790835, Length=477, Percent_Identity=22.8511530398323, Blast_Score=99, Evalue=7e-22,
Organism=Escherichia coli, GI48994988, Length=156, Percent_Identity=30.1282051282051, Blast_Score=66, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17533571, Length=695, Percent_Identity=27.1942446043165, Blast_Score=288, Evalue=7e-78,
Organism=Caenorhabditis elegans, GI17556745, Length=714, Percent_Identity=24.2296918767507, Blast_Score=172, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6323098, Length=695, Percent_Identity=29.2086330935252, Blast_Score=312, Evalue=1e-85,
Organism=Saccharomyces cerevisiae, GI6322359, Length=792, Percent_Identity=24.6212121212121, Blast_Score=236, Evalue=1e-62,
Organism=Drosophila melanogaster, GI24582462, Length=699, Percent_Identity=28.4692417739628, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI221458488, Length=706, Percent_Identity=24.5042492917847, Blast_Score=199, Evalue=6e-51,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: 3.6.5.3

Molecular weight: Translated: 76735; Mature: 76735

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQAVPTDQLRNIVVTGHSGTGKTMLCESLALSMGIINRLGSIEEGTTLSDYASDEIERKH
CCCCCCHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
SLNTSLIHGNWKDKKINIIDTPGLLDFHGDVKSAMRVADTVLITVNAATGVEVGTDTVWD
CCCCEEEECCCCCCEEEEEECCCCEECCCHHHHHHHHHCEEEEEEECCCCCCCCCCHHHH
YTQEYYKPTVFVLTKLDADRADFDTTLEALRDHFGHLVTPIQFPVEEGQNHHILIDVLLM
HHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCEEEEHHHHH
KQLEFNPDKPGSMEISEIPDLYRKKAEELHQQLVEAVAETDEELMNRFFDVGTLAEDELR
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AGIKSALVTRTFFPVFCTSPLHLIGSERLLNAIVNLCPSPIERGPEHAYCSVMNDEKLLD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEECCCCCCCC
PDPEGPTVAFIFKTMSEPRVGEISYVRVYSGHIETGHELIDAQTGQLEKLGQVYTMLGQK
CCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHCCC
KIPVDKLLAGDIGMVVKLKNSHTNDTLADKGVDCRISPIIFPEPVLSTAIVPTTQGDEEK
CCCHHHHHCCCCEEEEEEECCCCCCCHHCCCCCEEECCEECCCHHHHHEECCCCCCCHHH
ISSGLHHLHEEDPSFTIEHDTEFNQTILKTLGETHLDIIISRLFNKFNVKVETAPIRIPY
HHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHCEEEEECEEECCC
RETIRISASAQGKFKKQSGGRGQYGDVWIRIEPTERDSGFEFASEVVGGVVPTRYLPAVE
HHEEEEEECCCCCEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHH
KGIRETITHGLLAGYPLVDLKAVAYDGSHHPVDSSENAFKIAASMGFKAAFDKAKPLILE
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCEEEEHHCCCHHHHHCCCCHHHH
PLCSLTVQTPDQYTGEIVGEISSKRGRILGMDTDSRFQIIKAMIPQASLSDFHHALTRLT
HHHCCEECCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
HSRARYSYTFSHYEEAPSDVASKLIAEKNNES
HHHHHEEEEHHHHHCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MQAVPTDQLRNIVVTGHSGTGKTMLCESLALSMGIINRLGSIEEGTTLSDYASDEIERKH
CCCCCCHHHCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
SLNTSLIHGNWKDKKINIIDTPGLLDFHGDVKSAMRVADTVLITVNAATGVEVGTDTVWD
CCCCEEEECCCCCCEEEEEECCCCEECCCHHHHHHHHHCEEEEEEECCCCCCCCCCHHHH
YTQEYYKPTVFVLTKLDADRADFDTTLEALRDHFGHLVTPIQFPVEEGQNHHILIDVLLM
HHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHHCCCEEEHHCCCCCCEEEEHHHHH
KQLEFNPDKPGSMEISEIPDLYRKKAEELHQQLVEAVAETDEELMNRFFDVGTLAEDELR
HHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AGIKSALVTRTFFPVFCTSPLHLIGSERLLNAIVNLCPSPIERGPEHAYCSVMNDEKLLD
HHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCHHHCCCCCEEEEECCCCCCCC
PDPEGPTVAFIFKTMSEPRVGEISYVRVYSGHIETGHELIDAQTGQLEKLGQVYTMLGQK
CCCCCCEEEEEEECCCCCCCCCEEEEEEEECCCCCCHHHHCCCCCHHHHHHHHHHHHCCC
KIPVDKLLAGDIGMVVKLKNSHTNDTLADKGVDCRISPIIFPEPVLSTAIVPTTQGDEEK
CCCHHHHHCCCCEEEEEEECCCCCCCHHCCCCCEEECCEECCCHHHHHEECCCCCCCHHH
ISSGLHHLHEEDPSFTIEHDTEFNQTILKTLGETHLDIIISRLFNKFNVKVETAPIRIPY
HHHHHHHHHCCCCCEEEECCCCHHHHHHHHHCHHHHHHHHHHHHHHHCEEEEECEEECCC
RETIRISASAQGKFKKQSGGRGQYGDVWIRIEPTERDSGFEFASEVVGGVVPTRYLPAVE
HHEEEEEECCCCCEECCCCCCCCCCCEEEEEECCCCCCCHHHHHHHHCCCCCHHHHHHHH
KGIRETITHGLLAGYPLVDLKAVAYDGSHHPVDSSENAFKIAASMGFKAAFDKAKPLILE
HHHHHHHHHHHHCCCCCCEEEEEEECCCCCCCCCCCCCEEEEHHCCCHHHHHCCCCHHHH
PLCSLTVQTPDQYTGEIVGEISSKRGRILGMDTDSRFQIIKAMIPQASLSDFHHALTRLT
HHHCCEECCCCHHHHHHHHHHHCCCCCEEECCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
HSRARYSYTFSHYEEAPSDVASKLIAEKNNES
HHHHHEEEEHHHHHCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: GTP; H2O

Specific reaction: GTP + H2O = GDP + phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA