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The map label for this gene is dnaC [H]

Identifier: 193213468

GI number: 193213468

Start: 2009068

End: 2010609

Strand: Direct

Name: dnaC [H]

Synonym: Cpar_1829

Alternate gene names: 193213468

Gene position: 2009068-2010609 (Clockwise)

Preceding gene: 193213467

Following gene: 193213469

Centisome position: 87.76

GC content: 59.6

Gene sequence:

>1542_bases
ATGAAGCCGCGCGAAGCACAAGTAGATTTAAGCCGTGACATCGACTTCAGCAAAGAGAGTCGGGTGCCCCCCTACTCGAT
CGAGGTCGAACAGGAGGTGCTTGCCTGCATCCTGCTTGAAGACGACCCGATCGAACAGGTCATCCAGATTTTCGGCGACA
ACGGTGAATCGGTCTTTTACGAAAAGCGTCACCAGATCATCTACAAGGCGATGCTCACGCTTTACCAGAAGCGGCAGGGC
ATCGACCTCATCACGGTCAGCGAGGAGCTTTCGCGCGTCGGCGAGCTGGAGAACGTGGGAGGCCGCCCCTACCTCGGCGA
GCTTTCCGGCAAGGTGATCAGCTCGGCCAACATCGAGTACTACGCCCGGCTGGTGAAGGAGAAGTTCCTCTACCGGCGGC
TGATTTCGATTTCTTCGCACATTTCGAGCGCGGCCTACAACACCTCGATGGACATCTTCGACCTGGTCGAGAACGCCTCG
CAGCAGTTCTTCAACATCTCGCAGGCGGGCATCAAGAAGAAGGCCACCAGCATCAAGGAGCTGCTCAAGACCGCGACCAG
GATGATCGAGAATCTCGGCTCCTCCCACTCCTCGGTCACCGGCATCGGCTCGGGCTTTTCGGAGCTGGATGAATACACCG
CCGGGTTCCAGCCGTCGGACATGATTATCATCGCCGCACGCCCGTCGGCCGGTAAAACGGCATTCTCCCTCGCCCTTGCT
CGCAACGCCGCGGTGAACTTCAACACGCCGGTGCTCTTCTTCAGCCTTGAAATGGCCGAGATCCAGCTTGCCGTCAGGCT
GATGTGCGCCGAGGCCTACGTCGAGTCCCAGCTCGTGCGCCGAGGCCAGATTTCACCCGAGATGATGAACAAGATCATCA
ACAGCATGGACGCCCTGGCCGATGCCAAGCTATTCATCGACGACACGCCGGGCATCTCGATCATGGAGCTGACCGCCAAG
ACCCGCCGCATGAAGCAGGAGCACGGTATCGGCATGGTGGTGGTCGATTACCTCCAGCTCGTCACTCCAGTCAGGGACGG
CCGGTCGAACCGCGAGCAGGAGATCGCCCAGATTTCGCGTTCGCTCAAAGCGTTAGCCAAGGAGCTAAATATTCCGGTCA
TCGCGCTCGCGCAGCTCAACCGCTCCGTCGAACAGCGCTCCGGCGACCGGCGACCGCAGCTCAGTGACCTTCGCGAATCC
GGCTCGATCGAGCAGGACGCTGACATGGTGATGTTCCTGTCGAGGCCGGAGATGTACGGCATCAAGAACTTCGAGGACGG
CTCGTCGACCAAAGACATCACCGAAGTGGTGATCGGCAAGCAGCGTAACGGCCCGATCGGCACCATCAGGCTGCTGTTCC
TGAAAAATTATGGACGTTTCCAGTCGACGGCCAACAGCTACATCACGGCCAGCGAACCTGAACAGCATCAGGTCGAAGCG
CCACGCCCTGCGGCAGCGAGCTTTCCGGAGCCGCCATCCCTGCCCGAGCCGCCGCCGATTGACGACAGCTATCTCAACAA
CACGGATACCGCACCGTTTTAG

Upstream 100 bases:

>100_bases
GCTGGGAGGATGTGCAACTGCTCCGGGCGCATTACGACAAGGTCTGCCCGAACAGCTGACCGCATATGGAAACCATGATA
CGACGAGGAAAACAAGAGGA

Downstream 100 bases:

>100_bases
CTCTTCCGTCTATGGTTTACAAAAAAGCACCGAACCCCTCCGGCGATGTGCCGGACGCCAGTGAAACCCCCGGCCATCAA
TTCGGCCCGGCAGCAAAGGA

Product: replicative DNA helicase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 513; Mature: 513

Protein sequence:

>513_residues
MKPREAQVDLSRDIDFSKESRVPPYSIEVEQEVLACILLEDDPIEQVIQIFGDNGESVFYEKRHQIIYKAMLTLYQKRQG
IDLITVSEELSRVGELENVGGRPYLGELSGKVISSANIEYYARLVKEKFLYRRLISISSHISSAAYNTSMDIFDLVENAS
QQFFNISQAGIKKKATSIKELLKTATRMIENLGSSHSSVTGIGSGFSELDEYTAGFQPSDMIIIAARPSAGKTAFSLALA
RNAAVNFNTPVLFFSLEMAEIQLAVRLMCAEAYVESQLVRRGQISPEMMNKIINSMDALADAKLFIDDTPGISIMELTAK
TRRMKQEHGIGMVVVDYLQLVTPVRDGRSNREQEIAQISRSLKALAKELNIPVIALAQLNRSVEQRSGDRRPQLSDLRES
GSIEQDADMVMFLSRPEMYGIKNFEDGSSTKDITEVVIGKQRNGPIGTIRLLFLKNYGRFQSTANSYITASEPEQHQVEA
PRPAAASFPEPPSLPEPPPIDDSYLNNTDTAPF

Sequences:

>Translated_513_residues
MKPREAQVDLSRDIDFSKESRVPPYSIEVEQEVLACILLEDDPIEQVIQIFGDNGESVFYEKRHQIIYKAMLTLYQKRQG
IDLITVSEELSRVGELENVGGRPYLGELSGKVISSANIEYYARLVKEKFLYRRLISISSHISSAAYNTSMDIFDLVENAS
QQFFNISQAGIKKKATSIKELLKTATRMIENLGSSHSSVTGIGSGFSELDEYTAGFQPSDMIIIAARPSAGKTAFSLALA
RNAAVNFNTPVLFFSLEMAEIQLAVRLMCAEAYVESQLVRRGQISPEMMNKIINSMDALADAKLFIDDTPGISIMELTAK
TRRMKQEHGIGMVVVDYLQLVTPVRDGRSNREQEIAQISRSLKALAKELNIPVIALAQLNRSVEQRSGDRRPQLSDLRES
GSIEQDADMVMFLSRPEMYGIKNFEDGSSTKDITEVVIGKQRNGPIGTIRLLFLKNYGRFQSTANSYITASEPEQHQVEA
PRPAAASFPEPPSLPEPPPIDDSYLNNTDTAPF
>Mature_513_residues
MKPREAQVDLSRDIDFSKESRVPPYSIEVEQEVLACILLEDDPIEQVIQIFGDNGESVFYEKRHQIIYKAMLTLYQKRQG
IDLITVSEELSRVGELENVGGRPYLGELSGKVISSANIEYYARLVKEKFLYRRLISISSHISSAAYNTSMDIFDLVENAS
QQFFNISQAGIKKKATSIKELLKTATRMIENLGSSHSSVTGIGSGFSELDEYTAGFQPSDMIIIAARPSAGKTAFSLALA
RNAAVNFNTPVLFFSLEMAEIQLAVRLMCAEAYVESQLVRRGQISPEMMNKIINSMDALADAKLFIDDTPGISIMELTAK
TRRMKQEHGIGMVVVDYLQLVTPVRDGRSNREQEIAQISRSLKALAKELNIPVIALAQLNRSVEQRSGDRRPQLSDLRES
GSIEQDADMVMFLSRPEMYGIKNFEDGSSTKDITEVVIGKQRNGPIGTIRLLFLKNYGRFQSTANSYITASEPEQHQVEA
PRPAAASFPEPPSLPEPPPIDDSYLNNTDTAPF

Specific function: Participates In Initiation And Elongation During Chromosome Replication; It Exhibits DNA-Dependent ATPase Activity And Contains Distinct Active Sites For ATP Binding, DNA Binding, And Interaction With DNAc Protein, Primase, And Other Prepriming Proteins.

COG id: COG0305

COG function: function code L; Replicative DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SF4 helicase domain [H]

Homologues:

Organism=Escherichia coli, GI1790486, Length=454, Percent_Identity=44.4933920704846, Blast_Score=357, Evalue=1e-99,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR007692
- InterPro:   IPR007694
- InterPro:   IPR007693
- InterPro:   IPR016136 [H]

Pfam domain/function: PF00772 DnaB; PF03796 DnaB_C [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 57128; Mature: 57128

Theoretical pI: Translated: 4.97; Mature: 4.97

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPREAQVDLSRDIDFSKESRVPPYSIEVEQEVLACILLEDDPIEQVIQIFGDNGESVFY
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHEEEEECCCCHHHHHHHHCCCCCEEHH
EKRHQIIYKAMLTLYQKRQGIDLITVSEELSRVGELENVGGRPYLGELSGKVISSANIEY
HHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHCCCHHHCCCHHH
YARLVKEKFLYRRLISISSHISSAAYNTSMDIFDLVENASQQFFNISQAGIKKKATSIKE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKTATRMIENLGSSHSSVTGIGSGFSELDEYTAGFQPSDMIIIAARPSAGKTAFSLALA
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHH
RNAAVNFNTPVLFFSLEMAEIQLAVRLMCAEAYVESQLVRRGQISPEMMNKIINSMDALA
HCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DAKLFIDDTPGISIMELTAKTRRMKQEHGIGMVVVDYLQLVTPVRDGRSNREQEIAQISR
CCEEEEECCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SLKALAKELNIPVIALAQLNRSVEQRSGDRRPQLSDLRESGSIEQDADMVMFLSRPEMYG
HHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCC
IKNFEDGSSTKDITEVVIGKQRNGPIGTIRLLFLKNYGRFQSTANSYITASEPEQHQVEA
CCCCCCCCCHHHHHHHHHCCCCCCCCHHEEEEEHHCCCHHHHCCCCCEECCCCCCCCCCC
PRPAAASFPEPPSLPEPPPIDDSYLNNTDTAPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MKPREAQVDLSRDIDFSKESRVPPYSIEVEQEVLACILLEDDPIEQVIQIFGDNGESVFY
CCCCCCCCCCCCCCCCCCCCCCCCCEEEEHHHHHEEEEECCCCHHHHHHHHCCCCCEEHH
EKRHQIIYKAMLTLYQKRQGIDLITVSEELSRVGELENVGGRPYLGELSGKVISSANIEY
HHHHHHHHHHHHHHHHHHCCCEEEEEHHHHHHHHHHHHCCCCCCHHHHCCCHHHCCCHHH
YARLVKEKFLYRRLISISSHISSAAYNTSMDIFDLVENASQQFFNISQAGIKKKATSIKE
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LLKTATRMIENLGSSHSSVTGIGSGFSELDEYTAGFQPSDMIIIAARPSAGKTAFSLALA
HHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEEEEECCCCCCHHHHHHHH
RNAAVNFNTPVLFFSLEMAEIQLAVRLMCAEAYVESQLVRRGQISPEMMNKIINSMDALA
HCCEEECCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
DAKLFIDDTPGISIMELTAKTRRMKQEHGIGMVVVDYLQLVTPVRDGRSNREQEIAQISR
CCEEEEECCCCCEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
SLKALAKELNIPVIALAQLNRSVEQRSGDRRPQLSDLRESGSIEQDADMVMFLSRPEMYG
HHHHHHHHCCCCEEEHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCCCEEEEECCCCCCC
IKNFEDGSSTKDITEVVIGKQRNGPIGTIRLLFLKNYGRFQSTANSYITASEPEQHQVEA
CCCCCCCCCHHHHHHHHHCCCCCCCCHHEEEEEHHCCCHHHHCCCCCEECCCCCCCCCCC
PRPAAASFPEPPSLPEPPPIDDSYLNNTDTAPF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1312531 [H]