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The map label for this gene is engD [H]

Identifier: 193213388

GI number: 193213388

Start: 1918444

End: 1919535

Strand: Direct

Name: engD [H]

Synonym: Cpar_1749

Alternate gene names: 193213388

Gene position: 1918444-1919535 (Clockwise)

Preceding gene: 193213385

Following gene: 193213389

Centisome position: 83.8

GC content: 59.8

Gene sequence:

>1092_bases
ATGTCACTTCGCTGCGGCATTGTCGGTCTGCCCAATGTCGGCAAATCGACGCTGTTCAATGCCATTACGGCCAAACAGGC
CGAAGCCGCCAACTACCCATTCTGCACCATCGAACCCAACGTCGGCACCGTGCTGGTACCCGACAAGCGCCTCGGTGAAC
TGGCCAGCGTCGTCAAGACGCCGGTGATCGTTCCGGCGGTGCTCGAAATCGTCGATATTGCCGGTCTGGTCAAGGGGGCC
AGCAAGGGCGAAGGACTCGGCAACCAGTTCCTGTCGCACATCCGCGAAGTCGATGCGATCATCCACGTGGTGCGCTGTTT
CGAGGATTCGGACATCGTGCACGTCGAAGGCAAAATCGATCCGGTGGACGACATCGCCACCATCGAAACCGAGCTGATGC
TGGCCGATCTGGACAGCATGGAGAAACGCATGGACAAGCTGCGCAAGAACGCCCGCAAGGAGAAAGAGCTGCTGCCGCTG
GTCGATCTGGCTGAAAAGATCATCGCCGGACTCGGCGACGGCGTTCCGGTGCGCCGCATCACAGAGACTGACGAGGAGCG
CGAGCAGGCCCGCCAGTTTTTCCTTTTGACCTCCAAGCCGATTCTCTATGCGGCAAACGTCGCCGAAAACGACCTGCCGG
AGGGCAACGACTATTCAGCGAAGGTGGCCGAAATCGCGGCAGCCAACGGCGCGAACATGCTGGTCATCAGCGCAAAGGCG
GAAGCCGACATAGCCGAGCTTCCCGAAGAGGAGCGCCCGGAGTTCCTCGAAAGCCTCGGCCTTGAGATGTCGGGCCTCGA
CCGCCTCATCCGCGAAGCCTACGACCTGCTTGGCCTGCACAACTACTTCACGGCGGGCGTCAAGGAGGTTCACGCATGGA
CGATCCGCAAGGGCGCTGCTGCTCCGGAAGCTGCCGCAGCCATCCACACTGATTTCGAGAAGGGCTTCATCAGGGCGGAA
GTGATCGCGTACGATGACCTGATTTCTCTCGGCTCTGAGCAGAAGGCAAAAGAGGCCGGCAAAATGCGCTCCGAAGGCAA
GGAGTATATCGTGAAAGACGGGGACGTCATCGTCTTCAGGTTCAACGTGTAA

Upstream 100 bases:

>100_bases
GTAAAAAATTTATTTGCTTTTTCCAAACAGATTGATTACATGTTAAAACCGTCATTAACTGCGGTTCCTTTCGTTATTCG
TCAATCAACACGCTCCGCCC

Downstream 100 bases:

>100_bases
GCAGCCATGTCGCAGCACAAGCTCTCATCCTGCAGCCCGATCGGCATTTTCGACTCGGGCATCGGCGGCCTGACCGTGCT
CAAGGCCGTGCAGGCTGCGC

Product: GTP-dependent nucleic acid-binding protein EngD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 363; Mature: 362

Protein sequence:

>363_residues
MSLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDKRLGELASVVKTPVIVPAVLEIVDIAGLVKGA
SKGEGLGNQFLSHIREVDAIIHVVRCFEDSDIVHVEGKIDPVDDIATIETELMLADLDSMEKRMDKLRKNARKEKELLPL
VDLAEKIIAGLGDGVPVRRITETDEEREQARQFFLLTSKPILYAANVAENDLPEGNDYSAKVAEIAAANGANMLVISAKA
EADIAELPEEERPEFLESLGLEMSGLDRLIREAYDLLGLHNYFTAGVKEVHAWTIRKGAAAPEAAAAIHTDFEKGFIRAE
VIAYDDLISLGSEQKAKEAGKMRSEGKEYIVKDGDVIVFRFNV

Sequences:

>Translated_363_residues
MSLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDKRLGELASVVKTPVIVPAVLEIVDIAGLVKGA
SKGEGLGNQFLSHIREVDAIIHVVRCFEDSDIVHVEGKIDPVDDIATIETELMLADLDSMEKRMDKLRKNARKEKELLPL
VDLAEKIIAGLGDGVPVRRITETDEEREQARQFFLLTSKPILYAANVAENDLPEGNDYSAKVAEIAAANGANMLVISAKA
EADIAELPEEERPEFLESLGLEMSGLDRLIREAYDLLGLHNYFTAGVKEVHAWTIRKGAAAPEAAAAIHTDFEKGFIRAE
VIAYDDLISLGSEQKAKEAGKMRSEGKEYIVKDGDVIVFRFNV
>Mature_362_residues
SLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDKRLGELASVVKTPVIVPAVLEIVDIAGLVKGAS
KGEGLGNQFLSHIREVDAIIHVVRCFEDSDIVHVEGKIDPVDDIATIETELMLADLDSMEKRMDKLRKNARKEKELLPLV
DLAEKIIAGLGDGVPVRRITETDEEREQARQFFLLTSKPILYAANVAENDLPEGNDYSAKVAEIAAANGANMLVISAKAE
ADIAELPEEERPEFLESLGLEMSGLDRLIREAYDLLGLHNYFTAGVKEVHAWTIRKGAAAPEAAAAIHTDFEKGFIRAEV
IAYDDLISLGSEQKAKEAGKMRSEGKEYIVKDGDVIVFRFNV

Specific function: GTP-dependent nucleic acid-binding protein which may act as a translation factor [H]

COG id: COG0012

COG function: function code J; Predicted GTPase, probable translation factor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI58761500, Length=369, Percent_Identity=47.9674796747967, Blast_Score=318, Evalue=5e-87,
Organism=Homo sapiens, GI58761502, Length=227, Percent_Identity=42.7312775330396, Blast_Score=157, Evalue=1e-38,
Organism=Escherichia coli, GI1787454, Length=364, Percent_Identity=57.1428571428571, Blast_Score=408, Evalue=1e-115,
Organism=Escherichia coli, GI1789574, Length=127, Percent_Identity=34.6456692913386, Blast_Score=75, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17509631, Length=366, Percent_Identity=44.5355191256831, Blast_Score=309, Evalue=2e-84,
Organism=Saccharomyces cerevisiae, GI6319499, Length=370, Percent_Identity=41.8918918918919, Blast_Score=261, Evalue=1e-70,
Organism=Saccharomyces cerevisiae, GI6321773, Length=379, Percent_Identity=37.467018469657, Blast_Score=228, Evalue=1e-60,
Organism=Saccharomyces cerevisiae, GI6321649, Length=187, Percent_Identity=34.2245989304813, Blast_Score=89, Evalue=8e-19,
Organism=Saccharomyces cerevisiae, GI6321962, Length=171, Percent_Identity=26.9005847953216, Blast_Score=66, Evalue=8e-12,
Organism=Drosophila melanogaster, GI24640873, Length=367, Percent_Identity=46.0490463215259, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24640877, Length=367, Percent_Identity=46.0490463215259, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24640875, Length=367, Percent_Identity=46.0490463215259, Blast_Score=303, Evalue=2e-82,
Organism=Drosophila melanogaster, GI24640879, Length=325, Percent_Identity=44, Blast_Score=245, Evalue=3e-65,
Organism=Drosophila melanogaster, GI24585318, Length=148, Percent_Identity=30.4054054054054, Blast_Score=71, Evalue=1e-12,
Organism=Drosophila melanogaster, GI20129375, Length=111, Percent_Identity=34.2342342342342, Blast_Score=67, Evalue=2e-11,

Paralogues:

None

Copy number: 120 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR004396
- InterPro:   IPR013029
- InterPro:   IPR006073
- InterPro:   IPR002917
- InterPro:   IPR012676
- InterPro:   IPR023192 [H]

Pfam domain/function: PF01926 MMR_HSR1; PF06071 YchF-GTPase_C [H]

EC number: NA

Molecular weight: Translated: 39566; Mature: 39435

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00443 GATASE_TYPE_II

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDKRLGELASVVKT
CCCEECEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCHHHHHHHHHHHC
PVIVPAVLEIVDIAGLVKGASKGEGLGNQFLSHIREVDAIIHVVRCFEDSDIVHVEGKID
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PVDDIATIETELMLADLDSMEKRMDKLRKNARKEKELLPLVDLAEKIIAGLGDGVPVRRI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
TETDEEREQARQFFLLTSKPILYAANVAENDLPEGNDYSAKVAEIAAANGANMLVISAKA
CCCHHHHHHHHHEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCC
EADIAELPEEERPEFLESLGLEMSGLDRLIREAYDLLGLHNYFTAGVKEVHAWTIRKGAA
CCCHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APEAAAAIHTDFEKGFIRAEVIAYDDLISLGSEQKAKEAGKMRSEGKEYIVKDGDVIVFR
CCHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEE
FNV
ECC
>Mature Secondary Structure 
SLRCGIVGLPNVGKSTLFNAITAKQAEAANYPFCTIEPNVGTVLVPDKRLGELASVVKT
CCEECEEECCCCCHHHHHHHHHHHHHHCCCCCEEEECCCCCEEECCCHHHHHHHHHHHC
PVIVPAVLEIVDIAGLVKGASKGEGLGNQFLSHIREVDAIIHVVRCFEDSDIVHVEGKID
CHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCC
PVDDIATIETELMLADLDSMEKRMDKLRKNARKEKELLPLVDLAEKIIAGLGDGVPVRRI
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHH
TETDEEREQARQFFLLTSKPILYAANVAENDLPEGNDYSAKVAEIAAANGANMLVISAKA
CCCHHHHHHHHHEEEEECCCEEEEECCCCCCCCCCCCCHHHHHHHHHCCCCCEEEEECCC
EADIAELPEEERPEFLESLGLEMSGLDRLIREAYDLLGLHNYFTAGVKEVHAWTIRKGAA
CCCHHHCCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
APEAAAAIHTDFEKGFIRAEVIAYDDLISLGSEQKAKEAGKMRSEGKEYIVKDGDVIVFR
CCHHHHHHHHHHHHCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHCCCEEEEECCCEEEEE
FNV
ECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377 [H]