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The map label for this gene is era [H]

Identifier: 193213385

GI number: 193213385

Start: 1914703

End: 1915620

Strand: Direct

Name: era [H]

Synonym: Cpar_1746

Alternate gene names: 193213385

Gene position: 1914703-1915620 (Clockwise)

Preceding gene: 193213383

Following gene: 193213388

Centisome position: 83.64

GC content: 55.23

Gene sequence:

>918_bases
GTGCAGCCACCACCATTCTCCTGCGGCCATGCAACGTTCGTCGGCGCACCGAATGCCGGAAAATCGACCCTGCTGAATCG
CCTGCTGGATCACAAGCTATCGATTGTCACCCCAAAACCGCAAACTACAAGAAAAAAAATCACCGGAATCTACCACGACG
ACCGGAGCCAGATCATCATTCTCGACACGCCCGGCATCATGGACCCGAAGCAAAGCCTGCACGAATCGATGCTGGAAATC
ACCCGGCGGTCACTGCGTGACACGGATGTCATCGTGGCCCTTATCCCCTTACAGAAAGGAGAGGAGCCATTCGACAGAGC
GTTTGCCGACGAGCTGATCGAGCAATGGGTGCGTCCGGCGGACAAACCCTTCGTGATCGCCTTGAACAAGGCCGATCTTG
TTCCAGAAGAGACCGTCCACCAAGTGCAGAACGAAATCATGGAGCGCTACCACCCCATAGCCGTCCCGGCTTTGTCAGCG
CTCACCGGCAGCAACATACAGGAGCTGATCGACCTGCTCAGGCCGCTACTCCCGCTTGACGAGCCGATCTGGCCGGACGA
CATCCTGAGCACCGAACCCGAACGGTTCTTTGTCGGCGAAATCATCCGCGAAAAAATCTTTCTGCAGTTCGGCCGTGAAA
TCCCCTACTCGACCGAAGTGGTTATCGACGAGTTCAAAGAGCAACATGAAAACGACCCGAGTAAAAAGGATCTGATCCGC
TGCTCCATTATCGTCGAACGCAACAGCCAGAAGCAGATCATCATCGGTCAGAAAGGTGCGGCCATCAAAAAACTCGGCCA
GGCGGCCCGCAAAGAGATCGAAGAGCTGCTCGACCGTCCCGTCTTCCTTGAGATCTTTGTCAAGATCCGTCCCGACTGGC
GAAAGAAAAAGAACCTGCTCAAAAGCTACGGCTACTGA

Upstream 100 bases:

>100_bases
AGGTAAATCATGGTTATCTTGGGAATATAAATTCTTCCCCGCCGGAACAACCATCAGGAAAGTTTCGGCAAAAAAATATC
ACAGAACGGGAGCAACATCA

Downstream 100 bases:

>100_bases
AACAAAGTAGCGGAGAACGAAGAGATAACACCCTTTTTTGCTATAAACGGAAAAACCCCTTCACAAAAGGAAGGGGTTTT
TCCAGCTATGGCTGTAACAA

Product: GTP-binding protein Era

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MQPPPFSCGHATFVGAPNAGKSTLLNRLLDHKLSIVTPKPQTTRKKITGIYHDDRSQIIILDTPGIMDPKQSLHESMLEI
TRRSLRDTDVIVALIPLQKGEEPFDRAFADELIEQWVRPADKPFVIALNKADLVPEETVHQVQNEIMERYHPIAVPALSA
LTGSNIQELIDLLRPLLPLDEPIWPDDILSTEPERFFVGEIIREKIFLQFGREIPYSTEVVIDEFKEQHENDPSKKDLIR
CSIIVERNSQKQIIIGQKGAAIKKLGQAARKEIEELLDRPVFLEIFVKIRPDWRKKKNLLKSYGY

Sequences:

>Translated_305_residues
MQPPPFSCGHATFVGAPNAGKSTLLNRLLDHKLSIVTPKPQTTRKKITGIYHDDRSQIIILDTPGIMDPKQSLHESMLEI
TRRSLRDTDVIVALIPLQKGEEPFDRAFADELIEQWVRPADKPFVIALNKADLVPEETVHQVQNEIMERYHPIAVPALSA
LTGSNIQELIDLLRPLLPLDEPIWPDDILSTEPERFFVGEIIREKIFLQFGREIPYSTEVVIDEFKEQHENDPSKKDLIR
CSIIVERNSQKQIIIGQKGAAIKKLGQAARKEIEELLDRPVFLEIFVKIRPDWRKKKNLLKSYGY
>Mature_305_residues
MQPPPFSCGHATFVGAPNAGKSTLLNRLLDHKLSIVTPKPQTTRKKITGIYHDDRSQIIILDTPGIMDPKQSLHESMLEI
TRRSLRDTDVIVALIPLQKGEEPFDRAFADELIEQWVRPADKPFVIALNKADLVPEETVHQVQNEIMERYHPIAVPALSA
LTGSNIQELIDLLRPLLPLDEPIWPDDILSTEPERFFVGEIIREKIFLQFGREIPYSTEVVIDEFKEQHENDPSKKDLIR
CSIIVERNSQKQIIIGQKGAAIKKLGQAARKEIEELLDRPVFLEIFVKIRPDWRKKKNLLKSYGY

Specific function: An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism [H]

COG id: COG1159

COG function: function code R; GTPase

Gene ontology:

Cell location: Cytoplasm. Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH type-2 domain [H]

Homologues:

Organism=Homo sapiens, GI24307899, Length=322, Percent_Identity=23.9130434782609, Blast_Score=78, Evalue=1e-14,
Organism=Escherichia coli, GI1788919, Length=301, Percent_Identity=35.5481727574751, Blast_Score=179, Evalue=3e-46,
Organism=Escherichia coli, GI87082120, Length=184, Percent_Identity=28.804347826087, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005662
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR009019
- InterPro:   IPR004044
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF07650 KH_2; PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 34918; Mature: 34918

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50823 KH_TYPE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPPPFSCGHATFVGAPNAGKSTLLNRLLDHKLSIVTPKPQTTRKKITGIYHDDRSQIII
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHCEEECCCCEEEE
LDTPGIMDPKQSLHESMLEITRRSLRDTDVIVALIPLQKGEEPFDRAFADELIEQWVRPA
EECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
DKPFVIALNKADLVPEETVHQVQNEIMERYHPIAVPALSALTGSNIQELIDLLRPLLPLD
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
EPIWPDDILSTEPERFFVGEIIREKIFLQFGREIPYSTEVVIDEFKEQHENDPSKKDLIR
CCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHEE
CSIIVERNSQKQIIIGQKGAAIKKLGQAARKEIEELLDRPVFLEIFVKIRPDWRKKKNLL
EEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEHHEEECCCHHHHHHHH
KSYGY
HHCCC
>Mature Secondary Structure
MQPPPFSCGHATFVGAPNAGKSTLLNRLLDHKLSIVTPKPQTTRKKITGIYHDDRSQIII
CCCCCCCCCCEEEECCCCCCHHHHHHHHHHCCCEEECCCCCHHHHHHHCEEECCCCEEEE
LDTPGIMDPKQSLHESMLEITRRSLRDTDVIVALIPLQKGEEPFDRAFADELIEQWVRPA
EECCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCC
DKPFVIALNKADLVPEETVHQVQNEIMERYHPIAVPALSALTGSNIQELIDLLRPLLPLD
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
EPIWPDDILSTEPERFFVGEIIREKIFLQFGREIPYSTEVVIDEFKEQHENDPSKKDLIR
CCCCCHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHEE
CSIIVERNSQKQIIIGQKGAAIKKLGQAARKEIEELLDRPVFLEIFVKIRPDWRKKKNLL
EEEEEECCCCCEEEEECCCHHHHHHHHHHHHHHHHHHCCCEEEEHHEEECCCHHHHHHHH
KSYGY
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA