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The map label for this gene is bioC [C]

Identifier: 192289029

GI number: 192289029

Start: 654707

End: 655531

Strand: Reverse

Name: bioC [C]

Synonym: Rpal_0599

Alternate gene names: 192289029

Gene position: 655531-654707 (Counterclockwise)

Preceding gene: 192289030

Following gene: 192289028

Centisome position: 11.41

GC content: 70.55

Gene sequence:

>825_bases
ATGGCTGACTCGACGCCGATCCTGTTCGATCGCCGCCTGCTGGCGGCACGGCTGCACCGCGCCGCCGCGCTCGGCCCGGC
GCCTTTCCTGCTCGACCGCGTCGCCGAAGAGATGGACGAGCGGCTCCATGCCGTGCTGCGCGACTTCACCGAGGTCGCCG
ATCTCTGGACGCCCGGCGGGCTGAAGCTGCAGCGGTTTCCCAAGCTCGCGCATCTCGCGGTCGATCCGTCCGGCAGCGAA
GCTCTGCCGTTCGCGCCGGGATCGCTCGACCTCGTGGTCTCGGCGCTGGCGCTGCAATTCGCCAACGACCTGCCAGGCGT
GCTGGCGCAGCTTCGCCGTGCACTCAAGCCTGATGGACTGCTGCTCGCCGCACTGACCGGCGGCGAGACGCTGACCGAGC
TGCGCCAGGCTTTCGCTTCCGCCGAGGCCGAGATCGAAGGCGGCGTGTCGCCGCGCGTCGCGCCGGCCGCCGACCTGCGC
GATCTCGGCGCACTGCTGCAGCGCGCCGGCTTCGCGCTGCCGGTCACCGACGTCGACCGCGTCGTGGTGCGCTACGACCA
CGCGTTCGCCTTAATGCAGGATCTGCGGCGGATGGGCGCCACCAATGTGCTGATCGAGCGCCGCCGGACGCCGCTGCGCC
GCGCCACCCTGACACGGATGGCGCAGATCTATGCCGACCGCTTCAGCGACCCCGACGGCCGCATCCGCGCCACCTTCGAA
ATCGTCTGGCTGTCCGGTTGGTCCCCGCACGAAAGCCAGCAGCAGCCGCTGAAGCCGGGCTCGGCAAAGGTGAGTCTGGA
AGAGGCGGTGCGGGGGAAGCGCTAA

Upstream 100 bases:

>100_bases
ACGCGCTGGATGCGGTGCTGAAGATGTTCGAAGCCTCGCAGCAGGGCCCGGCCGCGGCCTCCAAGCTGAACTGATCGTGC
TTTCTCGATTCTGATTTGCC

Downstream 100 bases:

>100_bases
CGAATGCGATGTGGAGCACCGAAGCTGCTCCGTTGTCCCCGTCATCGCCGGGCTTGATGTTCAGCCCGGAGACATGACCT
ACGGGTGTTCGGAGACATAG

Product: type 11 methyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MADSTPILFDRRLLAARLHRAAALGPAPFLLDRVAEEMDERLHAVLRDFTEVADLWTPGGLKLQRFPKLAHLAVDPSGSE
ALPFAPGSLDLVVSALALQFANDLPGVLAQLRRALKPDGLLLAALTGGETLTELRQAFASAEAEIEGGVSPRVAPAADLR
DLGALLQRAGFALPVTDVDRVVVRYDHAFALMQDLRRMGATNVLIERRRTPLRRATLTRMAQIYADRFSDPDGRIRATFE
IVWLSGWSPHESQQQPLKPGSAKVSLEEAVRGKR

Sequences:

>Translated_274_residues
MADSTPILFDRRLLAARLHRAAALGPAPFLLDRVAEEMDERLHAVLRDFTEVADLWTPGGLKLQRFPKLAHLAVDPSGSE
ALPFAPGSLDLVVSALALQFANDLPGVLAQLRRALKPDGLLLAALTGGETLTELRQAFASAEAEIEGGVSPRVAPAADLR
DLGALLQRAGFALPVTDVDRVVVRYDHAFALMQDLRRMGATNVLIERRRTPLRRATLTRMAQIYADRFSDPDGRIRATFE
IVWLSGWSPHESQQQPLKPGSAKVSLEEAVRGKR
>Mature_273_residues
ADSTPILFDRRLLAARLHRAAALGPAPFLLDRVAEEMDERLHAVLRDFTEVADLWTPGGLKLQRFPKLAHLAVDPSGSEA
LPFAPGSLDLVVSALALQFANDLPGVLAQLRRALKPDGLLLAALTGGETLTELRQAFASAEAEIEGGVSPRVAPAADLRD
LGALLQRAGFALPVTDVDRVVVRYDHAFALMQDLRRMGATNVLIERRRTPLRRATLTRMAQIYADRFSDPDGRIRATFEI
VWLSGWSPHESQQQPLKPGSAKVSLEEAVRGKR

Specific function: Bioc Is Involved In An Early, But Chemically Unexplored, Step In The Conversion Of Pimelic Acid To Biotin. [C]

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI40018642, Length=287, Percent_Identity=36.9337979094077, Blast_Score=167, Evalue=8e-42,
Organism=Homo sapiens, GI86792933, Length=265, Percent_Identity=36.9811320754717, Blast_Score=151, Evalue=6e-37,
Organism=Caenorhabditis elegans, GI17535003, Length=185, Percent_Identity=35.1351351351351, Blast_Score=114, Evalue=6e-26,
Organism=Drosophila melanogaster, GI19922210, Length=300, Percent_Identity=34.6666666666667, Blast_Score=167, Evalue=9e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216 [H]

Pfam domain/function: PF08241 Methyltransf_11 [H]

EC number: NA

Molecular weight: Translated: 29975; Mature: 29844

Theoretical pI: Translated: 9.05; Mature: 9.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADSTPILFDRRLLAARLHRAAALGPAPFLLDRVAEEMDERLHAVLRDFTEVADLWTPGG
CCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LKLQRFPKLAHLAVDPSGSEALPFAPGSLDLVVSALALQFANDLPGVLAQLRRALKPDGL
CCHHHCCCHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCE
LLAALTGGETLTELRQAFASAEAEIEGGVSPRVAPAADLRDLGALLQRAGFALPVTDVDR
EEEEECCCHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
VVVRYDHAFALMQDLRRMGATNVLIERRRTPLRRATLTRMAQIYADRFSDPDGRIRATFE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
IVWLSGWSPHESQQQPLKPGSAKVSLEEAVRGKR
EEEECCCCCCCCCCCCCCCCCCCEEHHHHHCCCC
>Mature Secondary Structure 
ADSTPILFDRRLLAARLHRAAALGPAPFLLDRVAEEMDERLHAVLRDFTEVADLWTPGG
CCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
LKLQRFPKLAHLAVDPSGSEALPFAPGSLDLVVSALALQFANDLPGVLAQLRRALKPDGL
CCHHHCCCHHHEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCE
LLAALTGGETLTELRQAFASAEAEIEGGVSPRVAPAADLRDLGALLQRAGFALPVTDVDR
EEEEECCCHHHHHHHHHHHHCCHHHCCCCCCCCCCHHHHHHHHHHHHHCCCCCCHHHHHH
VVVRYDHAFALMQDLRRMGATNVLIERRRTPLRRATLTRMAQIYADRFSDPDGRIRATFE
HHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
IVWLSGWSPHESQQQPLKPGSAKVSLEEAVRGKR
EEEECCCCCCCCCCCCCCCCCCCEEHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9823893 [H]