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The map label for this gene is lepB [H]

Identifier: 190571647

GI number: 190571647

Start: 1347487

End: 1348272

Strand: Reverse

Name: lepB [H]

Synonym: WPa_1272

Alternate gene names: 190571647

Gene position: 1348272-1347487 (Counterclockwise)

Preceding gene: 190571649

Following gene: 190571642

Centisome position: 90.95

GC content: 32.95

Gene sequence:

>786_bases
ATGTGTTATGATAAGCTTAAATTTATAAAGAAAATAAAATTGAAAGAATTGAGAGAGAACCGGATAGCAAGAACGAGAAA
GTTTTTATCTTCACTGTTTTTTTTGCTACTAATTGCGCTATCAATACGTAGTTTTTTATTTGAGCCATTTCATATTCCTT
CTGGTTCAATGAAAAGCACTCTACTTGAGGGAGATTATATTTTTACTAGTAAATATTCATATGGTTATAGTAAACACTCT
TTTCCATTTTCTCCAAACATCTTTAGCGGTAGAATCTTTTATACCCCTCCGGAGCGTGGTGATATAATAGTTTTCAAGCC
TACAAGAAATGACAGCATTAGATTTGTTAAGCGGGTAATAGGAATACCGGGCGATAAAGTGCAAATGATAGAGGGGGAGT
TATATTTAAATGATCAGAAAGTAAAACGAAGACAAATTGAAAATTTTTTTGATTATGAGTCAAAGCGTAATATAGCAAGA
TACATCGAAACACTCCCGAGCGGCAAGGAGCATGAAATTCTAATAGATAATCTTTCTAATAAGTTATCATACAATACTCC
AGTTTATTATGTGCCTGATGATCAATTTTTTGTTATGGGAGACAATAGAAATAATTCTTTTGATAGCAGGTTTTCTGAAA
TTGGGTTAATACCAACTGAAAATATAGTTGGACGCGTAAGCATGGTTGGTTTATCGTTTAAATTAGGCAAAGTTGATTGG
TTGCCGTTTGATTTTAGGTTACCTATTGCTCTGAGATTTGACAGGGTACTTCACAAAGTTGTATGA

Upstream 100 bases:

>100_bases
GTCTATTGGTTATCAATCACTGTCAATTACTTGAGAGCTTATTTCGACTTTCGAAAAAGAGCAATAACACCCATGAGTAA
AATTTCACATTACCACTTTT

Downstream 100 bases:

>100_bases
ACTCTATCTGTCTGCTGATTCGCATAATTCTAAAGCAGAGTTTTCTAACTCAGAGATAGCATTATTAATGTTGTCTAAGT
CATTTTCCTGTAAAGCGTCT

Product: signal peptidase I

Products: NA

Alternate protein names: SPase I; Leader peptidase I [H]

Number of amino acids: Translated: 261; Mature: 261

Protein sequence:

>261_residues
MCYDKLKFIKKIKLKELRENRIARTRKFLSSLFFLLLIALSIRSFLFEPFHIPSGSMKSTLLEGDYIFTSKYSYGYSKHS
FPFSPNIFSGRIFYTPPERGDIIVFKPTRNDSIRFVKRVIGIPGDKVQMIEGELYLNDQKVKRRQIENFFDYESKRNIAR
YIETLPSGKEHEILIDNLSNKLSYNTPVYYVPDDQFFVMGDNRNNSFDSRFSEIGLIPTENIVGRVSMVGLSFKLGKVDW
LPFDFRLPIALRFDRVLHKVV

Sequences:

>Translated_261_residues
MCYDKLKFIKKIKLKELRENRIARTRKFLSSLFFLLLIALSIRSFLFEPFHIPSGSMKSTLLEGDYIFTSKYSYGYSKHS
FPFSPNIFSGRIFYTPPERGDIIVFKPTRNDSIRFVKRVIGIPGDKVQMIEGELYLNDQKVKRRQIENFFDYESKRNIAR
YIETLPSGKEHEILIDNLSNKLSYNTPVYYVPDDQFFVMGDNRNNSFDSRFSEIGLIPTENIVGRVSMVGLSFKLGKVDW
LPFDFRLPIALRFDRVLHKVV
>Mature_261_residues
MCYDKLKFIKKIKLKELRENRIARTRKFLSSLFFLLLIALSIRSFLFEPFHIPSGSMKSTLLEGDYIFTSKYSYGYSKHS
FPFSPNIFSGRIFYTPPERGDIIVFKPTRNDSIRFVKRVIGIPGDKVQMIEGELYLNDQKVKRRQIENFFDYESKRNIAR
YIETLPSGKEHEILIDNLSNKLSYNTPVYYVPDDQFFVMGDNRNNSFDSRFSEIGLIPTENIVGRVSMVGLSFKLGKVDW
LPFDFRLPIALRFDRVLHKVV

Specific function: Unknown

COG id: COG0681

COG function: function code U; Signal peptidase I

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S26 family [H]

Homologues:

Organism=Escherichia coli, GI1788921, Length=273, Percent_Identity=32.2344322344322, Blast_Score=119, Evalue=3e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000223
- InterPro:   IPR019758
- InterPro:   IPR019757
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: =3.4.21.89 [H]

Molecular weight: Translated: 30634; Mature: 30634

Theoretical pI: Translated: 10.13; Mature: 10.13

Prosite motif: PS00501 SPASE_I_1 ; PS00760 SPASE_I_2 ; PS00761 SPASE_I_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MCYDKLKFIKKIKLKELRENRIARTRKFLSSLFFLLLIALSIRSFLFEPFHIPSGSMKST
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LLEGDYIFTSKYSYGYSKHSFPFSPNIFSGRIFYTPPERGDIIVFKPTRNDSIRFVKRVI
EECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHH
GIPGDKVQMIEGELYLNDQKVKRRQIENFFDYESKRNIARYIETLPSGKEHEILIDNLSN
CCCCCCEEEEECEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCC
KLSYNTPVYYVPDDQFFVMGDNRNNSFDSRFSEIGLIPTENIVGRVSMVGLSFKLGKVDW
CCCCCCCEEECCCCCEEEEECCCCCCHHHHHHHCCCCCCHHHHHEEEEEEEEEEECCEEE
LPFDFRLPIALRFDRVLHKVV
CCCCEECCHHHHHHHHHHHHC
>Mature Secondary Structure
MCYDKLKFIKKIKLKELRENRIARTRKFLSSLFFLLLIALSIRSFLFEPFHIPSGSMKST
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHH
LLEGDYIFTSKYSYGYSKHSFPFSPNIFSGRIFYTPPERGDIIVFKPTRNDSIRFVKRVI
EECCCEEEEECCCCCCCCCCCCCCCCCCCCEEEECCCCCCCEEEEECCCCCHHHHHHHHH
GIPGDKVQMIEGELYLNDQKVKRRQIENFFDYESKRNIARYIETLPSGKEHEILIDNLSN
CCCCCCEEEEECEEEECHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCEEEEECCCC
KLSYNTPVYYVPDDQFFVMGDNRNNSFDSRFSEIGLIPTENIVGRVSMVGLSFKLGKVDW
CCCCCCCEEECCCCCEEEEECCCCCCHHHHHHHCCCCCCHHHHHEEEEEEEEEEECCEEE
LPFDFRLPIALRFDRVLHKVV
CCCCEECCHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA