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The map label for this gene is coxC [H]

Identifier: 190571526

GI number: 190571526

Start: 1228312

End: 1229139

Strand: Direct

Name: coxC [H]

Synonym: WPa_1145

Alternate gene names: 190571526

Gene position: 1228312-1229139 (Clockwise)

Preceding gene: 190571525

Following gene: 190571527

Centisome position: 82.86

GC content: 33.82

Gene sequence:

>828_bases
ATGAAAAGTAAAGAACATGATTTTCATTTAGTGGACCCAAGTCCCTGGCCAATTGCTATATCAGCAGCAATTCTTGTTCT
TGCACTTGGATTAGTTGGTACACTCCATAAACAAATTTCTGGAATATTTGGTTTAGTTTTGGGAATCTCTGCGGTATCAG
GAGTGCTGTTTTATTGGTGGAGAGATGTAATAAGAGAAGCAATTTATGATAAATGCCATACTGCCATTGTAAAACATGGA
CTCAAGCTTGCAATGTACTTATTTATCCTCTCGGAAGTTGTGTTTTTTATAGCGTTCTTTTGTTCATTCTTTAAAGCCTG
GCTTGATCCGGTTTTTTTATTTGAAGCGTTTTCTCCTACAAAAAAAGTTGAATGGCCCCCTGAAGGGATTTTACCACCGG
ATCCGTGGTCGTTACCATTTATGAATACACTAATATTATTACTTTCTGGTACAACGATTACTTCAGCACATCATTTTTTA
CTTGAAAATGATCAAAAGAGCATGATTAAAATGCTGTCTATAACTATATTGCTTGGGATGTTCTTTATAATAGTGCAAGC
AATTGAGTATTATGAAGCAAGTTTTTCTCTACAAGAAGCGGGAGAGAAACTTATCTATACATCCAACTTTTACATGATTA
CTGGTTTTCATTGTGTACATGTTATAATAGGGATAATATTCTTGTCAGTATGTTTATTTAGAGCTCGAAAAAATCAGATT
ACACCTCAAGATCATTTATGTTTTGAGTTTGCTTCTTGGTATTGGCACTTTGTCGATCTAGTATGGATATTTTTATTTCT
GTTTATTTATTGGTTAAGCCTTTATTAA

Upstream 100 bases:

>100_bases
GGAATAGCGCATATAATTTTTCAAAATTTGACCAAGATTTTAAGAAATATTGACAATTTTAAGCTAATTTGTATGCTTGA
TATGTATTTTTGAAGGTGAT

Downstream 100 bases:

>100_bases
GTGATTAAAATAATAGGCCTAGATCCAGGGATGAGTAAGACTGGTTGGGCCATTATTAGACTGGAAGAAAAGAATAATAT
TAAATTTTTGGGTGGCGGTA

Product: cytochrome c oxidase, subunit III

Products: NA

Alternate protein names: Cytochrome aa3 subunit 3; Cytochrome c oxidase polypeptide III [H]

Number of amino acids: Translated: 275; Mature: 275

Protein sequence:

>275_residues
MKSKEHDFHLVDPSPWPIAISAAILVLALGLVGTLHKQISGIFGLVLGISAVSGVLFYWWRDVIREAIYDKCHTAIVKHG
LKLAMYLFILSEVVFFIAFFCSFFKAWLDPVFLFEAFSPTKKVEWPPEGILPPDPWSLPFMNTLILLLSGTTITSAHHFL
LENDQKSMIKMLSITILLGMFFIIVQAIEYYEASFSLQEAGEKLIYTSNFYMITGFHCVHVIIGIIFLSVCLFRARKNQI
TPQDHLCFEFASWYWHFVDLVWIFLFLFIYWLSLY

Sequences:

>Translated_275_residues
MKSKEHDFHLVDPSPWPIAISAAILVLALGLVGTLHKQISGIFGLVLGISAVSGVLFYWWRDVIREAIYDKCHTAIVKHG
LKLAMYLFILSEVVFFIAFFCSFFKAWLDPVFLFEAFSPTKKVEWPPEGILPPDPWSLPFMNTLILLLSGTTITSAHHFL
LENDQKSMIKMLSITILLGMFFIIVQAIEYYEASFSLQEAGEKLIYTSNFYMITGFHCVHVIIGIIFLSVCLFRARKNQI
TPQDHLCFEFASWYWHFVDLVWIFLFLFIYWLSLY
>Mature_275_residues
MKSKEHDFHLVDPSPWPIAISAAILVLALGLVGTLHKQISGIFGLVLGISAVSGVLFYWWRDVIREAIYDKCHTAIVKHG
LKLAMYLFILSEVVFFIAFFCSFFKAWLDPVFLFEAFSPTKKVEWPPEGILPPDPWSLPFMNTLILLLSGTTITSAHHFL
LENDQKSMIKMLSITILLGMFFIIVQAIEYYEASFSLQEAGEKLIYTSNFYMITGFHCVHVIIGIIFLSVCLFRARKNQI
TPQDHLCFEFASWYWHFVDLVWIFLFLFIYWLSLY

Specific function: Cytochrome O Terminal Oxidase Complex Is The Component Of The Aerobic Respiratory Chain Of E.Coli That Predominates When Cells Are Grown At High Aeration. [C]

COG id: COG1845

COG function: function code C; Heme/copper-type cytochrome/quinol oxidase, subunit 3

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 3 family [H]

Homologues:

Organism=Homo sapiens, GI251831113, Length=271, Percent_Identity=43.5424354243542, Blast_Score=213, Evalue=1e-55,
Organism=Escherichia coli, GI1786633, Length=150, Percent_Identity=27.3333333333333, Blast_Score=62, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6226542, Length=270, Percent_Identity=35.1851851851852, Blast_Score=162, Evalue=6e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000298
- InterPro:   IPR013833 [H]

Pfam domain/function: PF00510 COX3 [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 31786; Mature: 31786

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS50253 COX3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure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CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA