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The map label for this gene is tenA [H]

Identifier: 190571525

GI number: 190571525

Start: 1227605

End: 1228264

Strand: Direct

Name: tenA [H]

Synonym: WPa_1144

Alternate gene names: 190571525

Gene position: 1227605-1228264 (Clockwise)

Preceding gene: 190571524

Following gene: 190571526

Centisome position: 82.81

GC content: 29.09

Gene sequence:

>660_bases
ATGTTTAGTGGTATAATTAAGAGTTATTATGGGTCAAATCTTTTAAAGGATATTATTGAGCATCCTTTCAATGTTGAATT
AGCAAATAATACTTTAAACATAGAAAACTTCAAATTTTATATACAACAAGATGCATTCTTTTTAGCTGATTATGTTCGTA
CTGTTTTAATGACTGCATCAAAAATGGAGAGTTGTAATAACATTGTTCCATTGATTGGGGTGGCTAAAGGAGGAATAGAG
ATTATGAGAGTGTTATACGACCACTACTTTACTGTATACTCCATAAATCGTGGAGAAAAGTCGCTTGAATGTTTCAATTT
TACTAACTTTCTTTTGTCTACTTCGTATAGCGACATTTATGAAGCTGTAACAGTTCTTTACTCTTGCCATTTTATATATA
AAATTATTGTTGATAATATGAGAAATAAAATTAAAAAAAATAATAGATATAAGGATTGGTTTGATTTTTTTGGCGGTAGT
TTGATGGAATCTGGATGTGTTGCTTTGGAAGATATTGTTGACGAGTATTGTAACAAAGCAAGGGAAAGTGAAAGAACCAG
AATGCTTGAATTATTTAAAATAACTGCACAATTTGAGTTAGACTTTTGGAATAGCGCATATAATTTTTCAAAATTTGACC
AAGATTTTAAGAAATATTGA

Upstream 100 bases:

>100_bases
TTTTAAGAGAGGTCTAGAGCTAGAAATAATGTTTTGGGATGAGATGTATTCTCTAGCATAATCTGTAGTATTAACACTAA
ATTATATTCTAGTTTATGTG

Downstream 100 bases:

>100_bases
CAATTTTAAGCTAATTTGTATGCTTGATATGTATTTTTGAAGGTGATATGAAAAGTAAAGAACATGATTTTCATTTAGTG
GACCCAAGTCCCTGGCCAAT

Product: Putative transcriptional activator, tenA family

Products: NA

Alternate protein names: Thiaminase II; Transcriptional activator tenA [H]

Number of amino acids: Translated: 219; Mature: 219

Protein sequence:

>219_residues
MFSGIIKSYYGSNLLKDIIEHPFNVELANNTLNIENFKFYIQQDAFFLADYVRTVLMTASKMESCNNIVPLIGVAKGGIE
IMRVLYDHYFTVYSINRGEKSLECFNFTNFLLSTSYSDIYEAVTVLYSCHFIYKIIVDNMRNKIKKNNRYKDWFDFFGGS
LMESGCVALEDIVDEYCNKARESERTRMLELFKITAQFELDFWNSAYNFSKFDQDFKKY

Sequences:

>Translated_219_residues
MFSGIIKSYYGSNLLKDIIEHPFNVELANNTLNIENFKFYIQQDAFFLADYVRTVLMTASKMESCNNIVPLIGVAKGGIE
IMRVLYDHYFTVYSINRGEKSLECFNFTNFLLSTSYSDIYEAVTVLYSCHFIYKIIVDNMRNKIKKNNRYKDWFDFFGGS
LMESGCVALEDIVDEYCNKARESERTRMLELFKITAQFELDFWNSAYNFSKFDQDFKKY
>Mature_219_residues
MFSGIIKSYYGSNLLKDIIEHPFNVELANNTLNIENFKFYIQQDAFFLADYVRTVLMTASKMESCNNIVPLIGVAKGGIE
IMRVLYDHYFTVYSINRGEKSLECFNFTNFLLSTSYSDIYEAVTVLYSCHFIYKIIVDNMRNKIKKNNRYKDWFDFFGGS
LMESGCVALEDIVDEYCNKARESERTRMLELFKITAQFELDFWNSAYNFSKFDQDFKKY

Specific function: Stimulates the production of several extracellular degradative enzymes at the transcriptional level, probably by interfering with degS and degU, which are required for this effect. Is not an essential protein, but affects the sporulation frequency [H]

COG id: COG0819

COG function: function code K; Putative transcription activator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiaminase-2 family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016084
- InterPro:   IPR004305 [H]

Pfam domain/function: PF03070 TENA_THI-4 [H]

EC number: =3.5.99.2 [H]

Molecular weight: Translated: 25799; Mature: 25799

Theoretical pI: Translated: 5.37; Mature: 5.37

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSGIIKSYYGSNLLKDIIEHPFNVELANNTLNIENFKFYIQQDAFFLADYVRTVLMTAS
CCHHHHHHHHCHHHHHHHHCCCCCEEECCCEECHHHEEEEEHHHHHHHHHHHHHHHHHHH
KMESCNNIVPLIGVAKGGIEIMRVLYDHYFTVYSINRGEKSLECFNFTNFLLSTSYSDIY
HHHHHCCCCHHHHCCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCHHHHH
EAVTVLYSCHFIYKIIVDNMRNKIKKNNRYKDWFDFFGGSLMESGCVALEDIVDEYCNKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHCCCHHHHHHHHHHHHHH
RESERTRMLELFKITAQFELDFWNSAYNFSKFDQDFKKY
HHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MFSGIIKSYYGSNLLKDIIEHPFNVELANNTLNIENFKFYIQQDAFFLADYVRTVLMTAS
CCHHHHHHHHCHHHHHHHHCCCCCEEECCCEECHHHEEEEEHHHHHHHHHHHHHHHHHHH
KMESCNNIVPLIGVAKGGIEIMRVLYDHYFTVYSINRGEKSLECFNFTNFLLSTSYSDIY
HHHHHCCCCHHHHCCCCHHHHHHHHHHHHHEEEEECCCCCHHHHHHHHHHHHHCCHHHHH
EAVTVLYSCHFIYKIIVDNMRNKIKKNNRYKDWFDFFGGSLMESGCVALEDIVDEYCNKA
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCHHHHHCCCHHHHHHHHHHHHHH
RESERTRMLELFKITAQFELDFWNSAYNFSKFDQDFKKY
HHHHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1898926; 9384377 [H]