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The map label for this gene is ruvA

Identifier: 190571380

GI number: 190571380

Start: 1056002

End: 1056574

Strand: Reverse

Name: ruvA

Synonym: WPa_0988

Alternate gene names: 190571380

Gene position: 1056574-1056002 (Counterclockwise)

Preceding gene: 190571383

Following gene: 190571379

Centisome position: 71.27

GC content: 33.86

Gene sequence:

>573_bases
ATGATAGGAAATCTAAGAGGAATAGTTGATGAGGTGTGTAGCGATCACATAATCCTGAATGTGAATGATGTTGGCTACAT
AGTATATCTTTCAGCCAAAACTTTAAGTGCTTGTTCGATTGGAAGTAGAGTAAAATTACTTATCGACACTTATGCAAATA
GCAGAGAAAACGTTACTCAGCTATATGGCTTTATAAGTAAAGAAGAACAGCAGTGTCTGCGCTTATTAGTTAAAGTGAGC
GGTGTCAGCTATAAAACCGCAATGTCAATTTTGAGCAAATTAACTCCAGAGCAACTGTTTTTGGCAATTATAAATGAGGA
TAAACTAGCACTTAAGGTGAGTGGACTTGGCCTGAAACTCATAAATCGAATTATTACTGAGCTGAATGGCAAAGTAAGTA
AATTAGAGATAAATAACAATCATTTTCACTCAATTAGTGAAGATGCTCTTTCAGCTTTGATCAATCTTGGATATGAAAGA
ACAAAAGCTTATGATACAATAAAAAAAATAGAAGATGAATCACCAAACTTGGACACTAAAGATATTATTCGTATGGCGCT
TAAAACAATATGA

Upstream 100 bases:

>100_bases
ACTTGTCTGCAATGATTGAAACTGGAACTACTTCTATAATGTTCGTTTGCTTGACCTAAGATTCAGGAGCATTTAAACTG
AATTTTATAAAGTACTAGAA

Downstream 100 bases:

>100_bases
AGTCAATATCATGTAGTAAGGAATACTCTGAAGATGTACGTAATTTAAATATCCGGCCTGAGCAACTTGATGATTTTGTC
GGGCAAAAAGACTTAATACA

Product: Holliday junction DNA helicase RuvA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MIGNLRGIVDEVCSDHIILNVNDVGYIVYLSAKTLSACSIGSRVKLLIDTYANSRENVTQLYGFISKEEQQCLRLLVKVS
GVSYKTAMSILSKLTPEQLFLAIINEDKLALKVSGLGLKLINRIITELNGKVSKLEINNNHFHSISEDALSALINLGYER
TKAYDTIKKIEDESPNLDTKDIIRMALKTI

Sequences:

>Translated_190_residues
MIGNLRGIVDEVCSDHIILNVNDVGYIVYLSAKTLSACSIGSRVKLLIDTYANSRENVTQLYGFISKEEQQCLRLLVKVS
GVSYKTAMSILSKLTPEQLFLAIINEDKLALKVSGLGLKLINRIITELNGKVSKLEINNNHFHSISEDALSALINLGYER
TKAYDTIKKIEDESPNLDTKDIIRMALKTI
>Mature_190_residues
MIGNLRGIVDEVCSDHIILNVNDVGYIVYLSAKTLSACSIGSRVKLLIDTYANSRENVTQLYGFISKEEQQCLRLLVKVS
GVSYKTAMSILSKLTPEQLFLAIINEDKLALKVSGLGLKLINRIITELNGKVSKLEINNNHFHSISEDALSALINLGYER
TKAYDTIKKIEDESPNLDTKDIIRMALKTI

Specific function: The ruvA-ruvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is an helicase that mediates the Holliday

COG id: COG0632

COG function: function code L; Holliday junction resolvasome, DNA-binding subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ruvA family

Homologues:

Organism=Escherichia coli, GI1788168, Length=206, Percent_Identity=28.6407766990291, Blast_Score=82, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RUVA_WOLPP (B3CMH6)

Other databases:

- EMBL:   AM999887
- RefSeq:   YP_001975738.1
- EnsemblBacteria:   EBWOLT00000000011
- GeneID:   6384676
- GenomeReviews:   AM999887_GR
- KEGG:   wpi:WPa_0988
- GeneTree:   EBGT00050000030959
- HOGENOM:   HBG635309
- OMA:   YKTAMSI
- ProtClustDB:   PRK14600
- HAMAP:   MF_00031
- InterPro:   IPR011114
- InterPro:   IPR013849
- InterPro:   IPR003583
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000085
- InterPro:   IPR010994
- Gene3D:   G3DSA:2.40.50.140
- SMART:   SM00278

Pfam domain/function: PF07499 RuvA_C; PF01330 RuvA_N; SSF50249 Nucleic_acid_OB; SSF47781 RuvA_2_like; SSF46929 RuvA_C-like

EC number: =3.6.4.12

Molecular weight: Translated: 21145; Mature: 21145

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIGNLRGIVDEVCSDHIILNVNDVGYIVYLSAKTLSACSIGSRVKLLIDTYANSRENVTQ
CCCCHHHHHHHHCCCCEEEEECCCEEEEEEECCHHHHHCCCCHHEEEEEHHCCCHHHHHH
LYGFISKEEQQCLRLLVKVSGVSYKTAMSILSKLTPEQLFLAIINEDKLALKVSGLGLKL
HHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHEEEEECCCCEEEEECCCCHHH
INRIITELNGKVSKLEINNNHFHSISEDALSALINLGYERTKAYDTIKKIEDESPNLDTK
HHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHH
DIIRMALKTI
HHHHHHHHCC
>Mature Secondary Structure
MIGNLRGIVDEVCSDHIILNVNDVGYIVYLSAKTLSACSIGSRVKLLIDTYANSRENVTQ
CCCCHHHHHHHHCCCCEEEEECCCEEEEEEECCHHHHHCCCCHHEEEEEHHCCCHHHHHH
LYGFISKEEQQCLRLLVKVSGVSYKTAMSILSKLTPEQLFLAIINEDKLALKVSGLGLKL
HHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHCCHHHHEEEEECCCCEEEEECCCCHHH
INRIITELNGKVSKLEINNNHFHSISEDALSALINLGYERTKAYDTIKKIEDESPNLDTK
HHHHHHHHCCCEEEEEECCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCHH
DIIRMALKTI
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA