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The map label for this gene is argD [H]

Identifier: 190571150

GI number: 190571150

Start: 814724

End: 815902

Strand: Reverse

Name: argD [H]

Synonym: WPa_0748

Alternate gene names: 190571150

Gene position: 815902-814724 (Counterclockwise)

Preceding gene: 190571151

Following gene: 190571149

Centisome position: 55.04

GC content: 36.47

Gene sequence:

>1179_bases
ATGGATCATGTTGTTAACGCTTATAATAGATCTGAAGCTTCTATAGTTAGAGGAGAAGGAGTATATCTCTTCGATAAGGA
TGGTAAAAAATATTTAGACTTTGCTGCAGGAATTTCTACAACCTCTCTAGGGCATTGTCATCCATACATTACAGATAAAC
TGAAGGAGCAACTGGATTCATTATGGCACTGCTCTAATATTTTTACTATTCCTCAGCAGGAAAGGCTTGCTCAGCGTTTA
ACAGAACTTACCTTTGCCGATAAAGTTTTTTTCTGCTCAAGTGGACTTGAAGCAACAGAAGCTGCAATTAAATTTATTCG
CCGCTATTTCTACTTAAATGGACAAGAAAAGCGCAGTCACATCATTACAATTGAAGGAGGTTTTCATGGCCGCAGTATTG
CTGCAATTTCAGCTGGGGGAAATGAAAAATCACGCGAAGGTTTTGCTCCACTCCTTTCTGGTTTTGATAAAGTTCCAAGA
AATAACATTGAAGCATTAGAAAAGAAAATCAATAGCGAAACAGCTGCCATATTTTTAGAGCCCATACAAAGTGAAGGCGG
AGTACATCCATTGGACGTAGAGTATCTTAAAAAAGTAAGAGAGATAACAAAAGCTCAAGGAATAATTTTATGCTTTGATG
AAGTGCAATGCGGATATGGACGGATTGGCTCTCTATTTTACTATCAAAATATAGGAGTTGAACCTGATATGCTCACTTGT
GCGAAGGCTATGGGTAATGGATTTCCTCTGGCTGCATGTTTAGTAAAAGATTATATAGCAGAAGCAATCACTCCAGGAAC
TCATGGGTCAACTTATGGAGGTAATCCACTTGCCATGACTGTTGGTAATGCAGTACTCGATGTAATGCTAAAGGAAGGCT
TTTTTGACCATGTTAAGAAGGTCAGTAAATATCTAAAAGAAAAGTTGTTGCCTTTGACTGAAGAATTTCCGAAGATCATT
TCAGAAGTTCGTGGGGAGGGTTTATTGATAGGGATAGAGCTTAGAGTACCTTTGGCTGATAAAATTGTTAAACAATCTCT
TGACAAAGGCTTAATAATGACTAATATTTTAAATAATAAGGTAATAAGAATAACTCCTCCACTTGTTGTTGAGAGTATGC
ATGTGAATGCAGTGTGTGATATATTTCATGATTTATTTTTTTATATTAAAGATATATAG

Upstream 100 bases:

>100_bases
TTTCTGAATTTTATGTTGAACTGTATAATACTAGCCCAATTTTTAGTTTAAGCAATATTAAGGGAAAGCTTTTTCATGCA
CAGTATAGATAATATTTAAA

Downstream 100 bases:

>100_bases
ACTTGCAAATGCTTCTTACAACATATAAAATCAACTCTGTTTCTATATCGCAATAACATCATACTTTAATGGATTGGTTA
TTGATTTCAGTATTGTCAGC

Product: acetylornithine transaminase protein

Products: NA

Alternate protein names: ACOAT [H]

Number of amino acids: Translated: 392; Mature: 392

Protein sequence:

>392_residues
MDHVVNAYNRSEASIVRGEGVYLFDKDGKKYLDFAAGISTTSLGHCHPYITDKLKEQLDSLWHCSNIFTIPQQERLAQRL
TELTFADKVFFCSSGLEATEAAIKFIRRYFYLNGQEKRSHIITIEGGFHGRSIAAISAGGNEKSREGFAPLLSGFDKVPR
NNIEALEKKINSETAAIFLEPIQSEGGVHPLDVEYLKKVREITKAQGIILCFDEVQCGYGRIGSLFYYQNIGVEPDMLTC
AKAMGNGFPLAACLVKDYIAEAITPGTHGSTYGGNPLAMTVGNAVLDVMLKEGFFDHVKKVSKYLKEKLLPLTEEFPKII
SEVRGEGLLIGIELRVPLADKIVKQSLDKGLIMTNILNNKVIRITPPLVVESMHVNAVCDIFHDLFFYIKDI

Sequences:

>Translated_392_residues
MDHVVNAYNRSEASIVRGEGVYLFDKDGKKYLDFAAGISTTSLGHCHPYITDKLKEQLDSLWHCSNIFTIPQQERLAQRL
TELTFADKVFFCSSGLEATEAAIKFIRRYFYLNGQEKRSHIITIEGGFHGRSIAAISAGGNEKSREGFAPLLSGFDKVPR
NNIEALEKKINSETAAIFLEPIQSEGGVHPLDVEYLKKVREITKAQGIILCFDEVQCGYGRIGSLFYYQNIGVEPDMLTC
AKAMGNGFPLAACLVKDYIAEAITPGTHGSTYGGNPLAMTVGNAVLDVMLKEGFFDHVKKVSKYLKEKLLPLTEEFPKII
SEVRGEGLLIGIELRVPLADKIVKQSLDKGLIMTNILNNKVIRITPPLVVESMHVNAVCDIFHDLFFYIKDI
>Mature_392_residues
MDHVVNAYNRSEASIVRGEGVYLFDKDGKKYLDFAAGISTTSLGHCHPYITDKLKEQLDSLWHCSNIFTIPQQERLAQRL
TELTFADKVFFCSSGLEATEAAIKFIRRYFYLNGQEKRSHIITIEGGFHGRSIAAISAGGNEKSREGFAPLLSGFDKVPR
NNIEALEKKINSETAAIFLEPIQSEGGVHPLDVEYLKKVREITKAQGIILCFDEVQCGYGRIGSLFYYQNIGVEPDMLTC
AKAMGNGFPLAACLVKDYIAEAITPGTHGSTYGGNPLAMTVGNAVLDVMLKEGFFDHVKKVSKYLKEKLLPLTEEFPKII
SEVRGEGLLIGIELRVPLADKIVKQSLDKGLIMTNILNNKVIRITPPLVVESMHVNAVCDIFHDLFFYIKDI

Specific function: Involved In Both The Arginine And Lysine Biosynthetic Pathways. [C]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. ArgD subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=383, Percent_Identity=34.9869451697128, Blast_Score=222, Evalue=5e-58,
Organism=Homo sapiens, GI13994255, Length=435, Percent_Identity=30.1149425287356, Blast_Score=184, Evalue=1e-46,
Organism=Homo sapiens, GI284507298, Length=298, Percent_Identity=34.8993288590604, Blast_Score=169, Evalue=4e-42,
Organism=Homo sapiens, GI37574042, Length=397, Percent_Identity=29.9748110831234, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI24119277, Length=395, Percent_Identity=27.5949367088608, Blast_Score=130, Evalue=1e-30,
Organism=Homo sapiens, GI226442705, Length=397, Percent_Identity=29.7229219143577, Blast_Score=129, Evalue=5e-30,
Organism=Homo sapiens, GI226442709, Length=369, Percent_Identity=29.5392953929539, Blast_Score=126, Evalue=4e-29,
Organism=Homo sapiens, GI188536080, Length=425, Percent_Identity=23.0588235294118, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI38679950, Length=425, Percent_Identity=23.0588235294118, Blast_Score=99, Evalue=7e-21,
Organism=Homo sapiens, GI38679946, Length=425, Percent_Identity=23.0588235294118, Blast_Score=99, Evalue=7e-21,
Organism=Escherichia coli, GI1789759, Length=372, Percent_Identity=40.3225806451613, Blast_Score=291, Evalue=4e-80,
Organism=Escherichia coli, GI1788044, Length=369, Percent_Identity=41.1924119241192, Blast_Score=288, Evalue=3e-79,
Organism=Escherichia coli, GI145693181, Length=364, Percent_Identity=33.7912087912088, Blast_Score=196, Evalue=2e-51,
Organism=Escherichia coli, GI1789016, Length=406, Percent_Identity=31.2807881773399, Blast_Score=188, Evalue=4e-49,
Organism=Escherichia coli, GI1787560, Length=395, Percent_Identity=31.1392405063291, Blast_Score=176, Evalue=2e-45,
Organism=Escherichia coli, GI1786991, Length=384, Percent_Identity=28.3854166666667, Blast_Score=130, Evalue=1e-31,
Organism=Escherichia coli, GI1786349, Length=331, Percent_Identity=28.3987915407855, Blast_Score=111, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI25144271, Length=379, Percent_Identity=36.6754617414248, Blast_Score=226, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI32564660, Length=428, Percent_Identity=33.1775700934579, Blast_Score=195, Evalue=4e-50,
Organism=Caenorhabditis elegans, GI25144274, Length=270, Percent_Identity=37.4074074074074, Blast_Score=164, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI71992977, Length=414, Percent_Identity=27.7777777777778, Blast_Score=135, Evalue=5e-32,
Organism=Caenorhabditis elegans, GI71981843, Length=153, Percent_Identity=37.2549019607843, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI17541228, Length=423, Percent_Identity=24.113475177305, Blast_Score=94, Evalue=2e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=393, Percent_Identity=36.3867684478371, Blast_Score=251, Evalue=1e-67,
Organism=Saccharomyces cerevisiae, GI6323470, Length=388, Percent_Identity=34.020618556701, Blast_Score=191, Evalue=2e-49,
Organism=Saccharomyces cerevisiae, GI6321456, Length=416, Percent_Identity=25.2403846153846, Blast_Score=88, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6324386, Length=321, Percent_Identity=24.2990654205607, Blast_Score=84, Evalue=3e-17,
Organism=Drosophila melanogaster, GI21357415, Length=380, Percent_Identity=33.6842105263158, Blast_Score=215, Evalue=3e-56,
Organism=Drosophila melanogaster, GI28574759, Length=418, Percent_Identity=32.0574162679426, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI161085790, Length=422, Percent_Identity=31.7535545023697, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI21356575, Length=412, Percent_Identity=30.3398058252427, Blast_Score=152, Evalue=5e-37,
Organism=Drosophila melanogaster, GI281366494, Length=421, Percent_Identity=26.3657957244656, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24667139, Length=421, Percent_Identity=26.3657957244656, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24667143, Length=421, Percent_Identity=26.3657957244656, Blast_Score=102, Evalue=3e-22,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.11 [H]

Molecular weight: Translated: 43576; Mature: 43576

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDHVVNAYNRSEASIVRGEGVYLFDKDGKKYLDFAAGISTTSLGHCHPYITDKLKEQLDS
CCCCCCCCCCCCCEEEECCCEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LWHCSNIFTIPQQERLAQRLTELTFADKVFFCSSGLEATEAAIKFIRRYFYLNGQEKRSH
HHHHCCEECCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCCE
IITIEGGFHGRSIAAISAGGNEKSREGFAPLLSGFDKVPRNNIEALEKKINSETAAIFLE
EEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEE
PIQSEGGVHPLDVEYLKKVREITKAQGIILCFDEVQCGYGRIGSLFYYQNIGVEPDMLTC
EHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHH
AKAMGNGFPLAACLVKDYIAEAITPGTHGSTYGGNPLAMTVGNAVLDVMLKEGFFDHVKK
HHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
VSKYLKEKLLPLTEEFPKIISEVRGEGLLIGIELRVPLADKIVKQSLDKGLIMTNILNNK
HHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHCCCCEEHHHHCCC
VIRITPPLVVESMHVNAVCDIFHDLFFYIKDI
EEEECCCHHHHHCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MDHVVNAYNRSEASIVRGEGVYLFDKDGKKYLDFAAGISTTSLGHCHPYITDKLKEQLDS
CCCCCCCCCCCCCEEEECCCEEEECCCCCHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHH
LWHCSNIFTIPQQERLAQRLTELTFADKVFFCSSGLEATEAAIKFIRRYFYLNGQEKRSH
HHHHCCEECCCCHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHCCCCCCCCE
IITIEGGFHGRSIAAISAGGNEKSREGFAPLLSGFDKVPRNNIEALEKKINSETAAIFLE
EEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCEEEEEEE
PIQSEGGVHPLDVEYLKKVREITKAQGIILCFDEVQCGYGRIGSLFYYQNIGVEPDMLTC
EHHCCCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCEEEEECCCCCCHHHHH
AKAMGNGFPLAACLVKDYIAEAITPGTHGSTYGGNPLAMTVGNAVLDVMLKEGFFDHVKK
HHHHCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHH
VSKYLKEKLLPLTEEFPKIISEVRGEGLLIGIELRVPLADKIVKQSLDKGLIMTNILNNK
HHHHHHHHCCCHHHHHHHHHHHHCCCEEEEEEEEECCHHHHHHHHHHCCCCEEHHHHCCC
VIRITPPLVVESMHVNAVCDIFHDLFFYIKDI
EEEECCCHHHHHCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11743193; 11743194 [H]