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The map label for this gene is ndk [H]

Identifier: 190571151

GI number: 190571151

Start: 816025

End: 816444

Strand: Reverse

Name: ndk [H]

Synonym: WPa_0749

Alternate gene names: 190571151

Gene position: 816444-816025 (Counterclockwise)

Preceding gene: 190571155

Following gene: 190571150

Centisome position: 55.07

GC content: 34.29

Gene sequence:

>420_bases
ATGGCAATTGAGAGAACACTTTCGATATTAAAACCTGATGCAGTAAAAAATAATATTACAGGCAGTATAAATTCTTACAT
TGAAAAATCTGGACTAAAAATTATAGCACAGAGAAAGATGCTGCTGACAAAAAAACAAGCAGAGCTGTTTTATGAAATTC
ATAAGGATAGGCCTTTTTTTGGAGAGTTGGTGGAATTTATGACTTCTGGGTCTGTGATAGTTCAAGTTTTAATCGGTGAA
AATGCAGTCAGTAAATACAGACAAATCATGGGTGCTACAGATCCAAAACAGGCAGATAAAGGTACAATTAGGGGTGATTT
TGCTAATGATATTAGTGAAAATAGAGTGCATGGTTCTGATAGTCTAGAGAATGCTCATAGAGAAATAGCTTTCTTTTTTG
CTGAATGTGAATTGGTGTAG

Upstream 100 bases:

>100_bases
ACCCCTTGATGTTTTATTCTTGACTATAAATAAAAAATCTCTTTGATGGAACAAAAATTCACAATAAAGTAAATATACGA
TCTTAATATAAGGGAATGAT

Downstream 100 bases:

>100_bases
TTTTACCTTTTTACATATTAAATTTCTGAATTTTATGTTGAACTGTATAATACTAGCCCAATTTTTAGTTTAAGCAATAT
TAAGGGAAAGCTTTTTCATG

Product: nucleoside diphosphate kinase

Products: NA

Alternate protein names: NDK; NDP kinase; Nucleoside-2-P kinase [H]

Number of amino acids: Translated: 139; Mature: 138

Protein sequence:

>139_residues
MAIERTLSILKPDAVKNNITGSINSYIEKSGLKIIAQRKMLLTKKQAELFYEIHKDRPFFGELVEFMTSGSVIVQVLIGE
NAVSKYRQIMGATDPKQADKGTIRGDFANDISENRVHGSDSLENAHREIAFFFAECELV

Sequences:

>Translated_139_residues
MAIERTLSILKPDAVKNNITGSINSYIEKSGLKIIAQRKMLLTKKQAELFYEIHKDRPFFGELVEFMTSGSVIVQVLIGE
NAVSKYRQIMGATDPKQADKGTIRGDFANDISENRVHGSDSLENAHREIAFFFAECELV
>Mature_138_residues
AIERTLSILKPDAVKNNITGSINSYIEKSGLKIIAQRKMLLTKKQAELFYEIHKDRPFFGELVEFMTSGSVIVQVLIGEN
AVSKYRQIMGATDPKQADKGTIRGDFANDISENRVHGSDSLENAHREIAFFFAECELV

Specific function: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate [H]

COG id: COG0105

COG function: function code F; Nucleoside diphosphate kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NDK family [H]

Homologues:

Organism=Homo sapiens, GI37693993, Length=138, Percent_Identity=40.5797101449275, Blast_Score=115, Evalue=1e-26,
Organism=Homo sapiens, GI66392203, Length=137, Percent_Identity=38.6861313868613, Blast_Score=109, Evalue=9e-25,
Organism=Homo sapiens, GI66392227, Length=137, Percent_Identity=38.6861313868613, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI66392205, Length=137, Percent_Identity=38.6861313868613, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI4505409, Length=137, Percent_Identity=38.6861313868613, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI66392192, Length=137, Percent_Identity=38.6861313868613, Blast_Score=108, Evalue=1e-24,
Organism=Homo sapiens, GI38045913, Length=136, Percent_Identity=39.7058823529412, Blast_Score=107, Evalue=3e-24,
Organism=Homo sapiens, GI4557797, Length=136, Percent_Identity=39.7058823529412, Blast_Score=107, Evalue=3e-24,
Organism=Homo sapiens, GI4826862, Length=136, Percent_Identity=37.5, Blast_Score=105, Evalue=9e-24,
Organism=Homo sapiens, GI37574614, Length=133, Percent_Identity=34.5864661654135, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI7019465, Length=133, Percent_Identity=34.5864661654135, Blast_Score=92, Evalue=2e-19,
Organism=Homo sapiens, GI5031951, Length=138, Percent_Identity=35.5072463768116, Blast_Score=89, Evalue=9e-19,
Organism=Homo sapiens, GI4505413, Length=136, Percent_Identity=31.6176470588235, Blast_Score=79, Evalue=1e-15,
Organism=Homo sapiens, GI148839372, Length=138, Percent_Identity=31.1594202898551, Blast_Score=77, Evalue=4e-15,
Organism=Homo sapiens, GI30023828, Length=135, Percent_Identity=32.5925925925926, Blast_Score=77, Evalue=5e-15,
Organism=Escherichia coli, GI1788866, Length=139, Percent_Identity=52.5179856115108, Blast_Score=156, Evalue=4e-40,
Organism=Caenorhabditis elegans, GI17506807, Length=135, Percent_Identity=40.7407407407407, Blast_Score=117, Evalue=2e-27,
Organism=Saccharomyces cerevisiae, GI6322783, Length=136, Percent_Identity=41.9117647058824, Blast_Score=111, Evalue=3e-26,
Organism=Drosophila melanogaster, GI45549037, Length=136, Percent_Identity=42.6470588235294, Blast_Score=115, Evalue=1e-26,
Organism=Drosophila melanogaster, GI18860097, Length=136, Percent_Identity=31.6176470588235, Blast_Score=77, Evalue=4e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001564
- InterPro:   IPR023005 [H]

Pfam domain/function: PF00334 NDK [H]

EC number: =2.7.4.6 [H]

Molecular weight: Translated: 15595; Mature: 15464

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00469 NDP_KINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAIERTLSILKPDAVKNNITGSINSYIEKSGLKIIAQRKMLLTKKQAELFYEIHKDRPFF
CCHHHHHHHHCCHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GELVEFMTSGSVIVQVLIGENAVSKYRQIMGATDPKQADKGTIRGDFANDISENRVHGSD
HHHHHHHCCCHHHEEEHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCHHCCCCCCCH
SLENAHREIAFFFAECELV
HHHHHHHHHHHHHEEEECC
>Mature Secondary Structure 
AIERTLSILKPDAVKNNITGSINSYIEKSGLKIIAQRKMLLTKKQAELFYEIHKDRPFF
CHHHHHHHHCCHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
GELVEFMTSGSVIVQVLIGENAVSKYRQIMGATDPKQADKGTIRGDFANDISENRVHGSD
HHHHHHHCCCHHHEEEHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHCHHCCCCCCCH
SLENAHREIAFFFAECELV
HHHHHHHHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA