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The map label for this gene is clpX [H]

Identifier: 190570983

GI number: 190570983

Start: 615190

End: 616467

Strand: Direct

Name: clpX [H]

Synonym: WPa_0571

Alternate gene names: 190570983

Gene position: 615190-616467 (Clockwise)

Preceding gene: 190570982

Following gene: 190570984

Centisome position: 41.5

GC content: 36.15

Gene sequence:

>1278_bases
ATGGATAACAATAATGATTTACACTACTGTTCTTTTTGTAACAAGGCACAAAACGAAGTAGATAAATTGATTACTAACTC
TTCAGATGGTTTAAAGGTGTTCATTTGTAATGAATGCATAGAGTTATCCCATAAAGCAATAAGTCAAAAGAAAGAGAGAG
CTTTTAATTCAGATCATATATCTGATATGAAGCTATTACTAAAGAAACCTGAAGATATAAAAATTTTTCTTAGTAAGCAT
GTTGTAGGTCAGGAACATGCGCAACACGTTTTATCTGTGGCTATGTATAACCATTGTCAATCCATGGTGCAACTTCATTC
TATAAGTGATATTGAAATTGAGAAGTCAAATATAATGCTTATTGGCCCTACTGGTTCTGGTAAGACTTTGCTAGCAAAAA
CACTTGCTAAAGTTTCAGATGTGCCATTTGCTATGGCCGATGCGACAACTTTGACTGAGGCAGGTTATGTAGGTGATGAT
GTAGAAAGCGTGTTGTCACGTCTATTACAAGCTGCAAATTATGATGTTGCAAAGGCACAGCATGGTATAGTGTTTATCGA
TGAAATAGACAAGATTACAAGAAAATCTGAAAGCACTTCAATAACCCGTGACGTTTCAGGTGAAGGGGTCCAGCAAGCTC
TGCTTAAGATTATGGAGGGTACAGTTGCTTATGTTCCGCCACAAGGAGGGCGAAAACACCCGCAACAAGAGTTTATACAA
GTAGATACTAGTAATATACTATTTATTTGTGGAGGAGCTTTTGAAGGCCTAAATAAAATTATTGAGGCAAGAAAAAAGGG
AACATCAGTTGGCTTTGGAGCAGATATAAGTCAGTCTAAAGCACAAAAGAAAAAAAATGCTTTACGCGATGCTCAACCTG
AGGACTTAATCAAATTCGGTTTGATACCCGAATTTGTAGGACGAGTTCCAATAACTGCTGTTCTAGATGAGCTGGATCAC
GAAGATTTAATACATGTGTTGACAGAGCCAAGAAATGCGCTAGTAAAACAATATAAAGCATTGCTTGCATTTAGTAAAGT
AAACCTTGAGTTTTCAGATGAAGCAATATCAGCTATTGCTAAAAAAGCTATAAGCTATAAAACAGGTGCAAGGATGTTAC
GTGCTATCTTAGAGTCACTTTTGCTTGATGTTATGTATATATCCGGCAACGGAGGTTTTGAAGGTAGCACTATAACGGTT
ACTAAGAAAATGGTAGAATTAGGCAAAGTGACGATTAATCATAATAATAAGGGTAGTGTTATAACGGTTAATGATTAA

Upstream 100 bases:

>100_bases
ATCCTGAAGAAGCAATGAAAACTGGCTTAATTGACAGAGTAATAGCTGAGCGTAAAGATATGAAGATTGAAAATATTAAA
GTTAAACAAAAGGTAGTTTA

Downstream 100 bases:

>100_bases
TTTGAGGCATATATTATGAGTATTGGACGTGCTGTAAACTTTAATTCTACTGTATTACCAGTATTACCTCTAAGAGATGT
AGTAATTTTTCCAAATATAA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 425; Mature: 425

Protein sequence:

>425_residues
MDNNNDLHYCSFCNKAQNEVDKLITNSSDGLKVFICNECIELSHKAISQKKERAFNSDHISDMKLLLKKPEDIKIFLSKH
VVGQEHAQHVLSVAMYNHCQSMVQLHSISDIEIEKSNIMLIGPTGSGKTLLAKTLAKVSDVPFAMADATTLTEAGYVGDD
VESVLSRLLQAANYDVAKAQHGIVFIDEIDKITRKSESTSITRDVSGEGVQQALLKIMEGTVAYVPPQGGRKHPQQEFIQ
VDTSNILFICGGAFEGLNKIIEARKKGTSVGFGADISQSKAQKKKNALRDAQPEDLIKFGLIPEFVGRVPITAVLDELDH
EDLIHVLTEPRNALVKQYKALLAFSKVNLEFSDEAISAIAKKAISYKTGARMLRAILESLLLDVMYISGNGGFEGSTITV
TKKMVELGKVTINHNNKGSVITVND

Sequences:

>Translated_425_residues
MDNNNDLHYCSFCNKAQNEVDKLITNSSDGLKVFICNECIELSHKAISQKKERAFNSDHISDMKLLLKKPEDIKIFLSKH
VVGQEHAQHVLSVAMYNHCQSMVQLHSISDIEIEKSNIMLIGPTGSGKTLLAKTLAKVSDVPFAMADATTLTEAGYVGDD
VESVLSRLLQAANYDVAKAQHGIVFIDEIDKITRKSESTSITRDVSGEGVQQALLKIMEGTVAYVPPQGGRKHPQQEFIQ
VDTSNILFICGGAFEGLNKIIEARKKGTSVGFGADISQSKAQKKKNALRDAQPEDLIKFGLIPEFVGRVPITAVLDELDH
EDLIHVLTEPRNALVKQYKALLAFSKVNLEFSDEAISAIAKKAISYKTGARMLRAILESLLLDVMYISGNGGFEGSTITV
TKKMVELGKVTINHNNKGSVITVND
>Mature_425_residues
MDNNNDLHYCSFCNKAQNEVDKLITNSSDGLKVFICNECIELSHKAISQKKERAFNSDHISDMKLLLKKPEDIKIFLSKH
VVGQEHAQHVLSVAMYNHCQSMVQLHSISDIEIEKSNIMLIGPTGSGKTLLAKTLAKVSDVPFAMADATTLTEAGYVGDD
VESVLSRLLQAANYDVAKAQHGIVFIDEIDKITRKSESTSITRDVSGEGVQQALLKIMEGTVAYVPPQGGRKHPQQEFIQ
VDTSNILFICGGAFEGLNKIIEARKKGTSVGFGADISQSKAQKKKNALRDAQPEDLIKFGLIPEFVGRVPITAVLDELDH
EDLIHVLTEPRNALVKQYKALLAFSKVNLEFSDEAISAIAKKAISYKTGARMLRAILESLLLDVMYISGNGGFEGSTITV
TKKMVELGKVTINHNNKGSVITVND

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=299, Percent_Identity=51.1705685618729, Blast_Score=297, Evalue=1e-80,
Organism=Escherichia coli, GI1786642, Length=388, Percent_Identity=58.7628865979381, Blast_Score=456, Evalue=1e-129,
Organism=Escherichia coli, GI1790366, Length=226, Percent_Identity=35.8407079646018, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI71982905, Length=324, Percent_Identity=44.1358024691358, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71982908, Length=324, Percent_Identity=44.1358024691358, Blast_Score=259, Evalue=1e-69,
Organism=Caenorhabditis elegans, GI71988663, Length=395, Percent_Identity=38.4810126582278, Blast_Score=225, Evalue=4e-59,
Organism=Caenorhabditis elegans, GI71988660, Length=255, Percent_Identity=38.8235294117647, Blast_Score=157, Evalue=1e-38,
Organism=Saccharomyces cerevisiae, GI6319704, Length=403, Percent_Identity=38.4615384615385, Blast_Score=246, Evalue=5e-66,
Organism=Drosophila melanogaster, GI24648291, Length=306, Percent_Identity=49.0196078431373, Blast_Score=291, Evalue=5e-79,
Organism=Drosophila melanogaster, GI24648289, Length=306, Percent_Identity=49.0196078431373, Blast_Score=291, Evalue=5e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46585; Mature: 46585

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDNNNDLHYCSFCNKAQNEVDKLITNSSDGLKVFICNECIELSHKAISQKKERAFNSDHI
CCCCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCH
SDMKLLLKKPEDIKIFLSKHVVGQEHAQHVLSVAMYNHCQSMVQLHSISDIEIEKSNIML
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEE
IGPTGSGKTLLAKTLAKVSDVPFAMADATTLTEAGYVGDDVESVLSRLLQAANYDVAKAQ
EECCCCCHHHHHHHHHHHHCCCEEHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCC
HGIVFIDEIDKITRKSESTSITRDVSGEGVQQALLKIMEGTVAYVPPQGGRKHPQQEFIQ
CCEEEEEHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHE
VDTSNILFICGGAFEGLNKIIEARKKGTSVGFGADISQSKAQKKKNALRDAQPEDLIKFG
ECCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHC
LIPEFVGRVPITAVLDELDHEDLIHVLTEPRNALVKQYKALLAFSKVNLEFSDEAISAIA
CCHHHHCCCCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
KKAISYKTGARMLRAILESLLLDVMYISGNGGFEGSTITVTKKMVELGKVTINHNNKGSV
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEHHHHHHHHCCEEEEECCCCCE
ITVND
EEECC
>Mature Secondary Structure
MDNNNDLHYCSFCNKAQNEVDKLITNSSDGLKVFICNECIELSHKAISQKKERAFNSDHI
CCCCCCEEHHHHHHHHHHHHHHHHCCCCCCEEEEEEHHHHHHHHHHHHHHHHHCCCCCCH
SDMKLLLKKPEDIKIFLSKHVVGQEHAQHVLSVAMYNHCQSMVQLHSISDIEIEKSNIML
HHHHHHHCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEE
IGPTGSGKTLLAKTLAKVSDVPFAMADATTLTEAGYVGDDVESVLSRLLQAANYDVAKAQ
EECCCCCHHHHHHHHHHHHCCCEEHHCCHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHCC
HGIVFIDEIDKITRKSESTSITRDVSGEGVQQALLKIMEGTVAYVPPQGGRKHPQQEFIQ
CCEEEEEHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCCCCCCCCHHHHHE
VDTSNILFICGGAFEGLNKIIEARKKGTSVGFGADISQSKAQKKKNALRDAQPEDLIKFG
ECCCCEEEEECCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHC
LIPEFVGRVPITAVLDELDHEDLIHVLTEPRNALVKQYKALLAFSKVNLEFSDEAISAIA
CCHHHHCCCCHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCEECHHHHHHHH
KKAISYKTGARMLRAILESLLLDVMYISGNGGFEGSTITVTKKMVELGKVTINHNNKGSV
HHHHHHHHHHHHHHHHHHHHHHHEEEEECCCCCCCCEEEHHHHHHHHCCEEEEECCCCCE
ITVND
EEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA