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The map label for this gene is gltP [C]

Identifier: 190570892

GI number: 190570892

Start: 508070

End: 509254

Strand: Reverse

Name: gltP [C]

Synonym: WPa_0471

Alternate gene names: 190570892

Gene position: 509254-508070 (Counterclockwise)

Preceding gene: 190570894

Following gene: 190570891

Centisome position: 34.35

GC content: 33.42

Gene sequence:

>1185_bases
ATGCGCAAACTTGCAATACTCTTTTCTATACTGTTTGCGGTAATTGCTTACTATTTAAACAATGAAGTAATATTTGAAAT
AGCAAAGCTATTTAGCGATATATTCATCAGTCTGTTGAAATTGATTAGCTTACCTTTAGTTTTTCTATCTATAGTGTCCA
CAATTTCAGGGCTTAAAGACTCAATTGAAATTAAAGTATTACTTAAGAAGACGCTGTTTTACACGCTGTTTACAACAATT
GTAGCTGCATTTGTTGCGTTATCTTTCTATTTATTCATAGACCCAGTAAGAAAAAATTTCATAAGTAACACAATAGAAAG
TGTGAGTGACAGCAACCACAATTACTTCTCATACTTAAAATCACTCATTCCATCAAATTTTGTGCAAGTTTTTCTTGAAA
ATAACGTTATTGGCAGCATATTGATTGCTTTTTTGATGGGTGGAGCTATTATTTCGCTCTCAAAAGAAAAACAGGATATA
TTACACCAAATATTCTCTGCACTGTTTGATACACTTCTTAAAATTGCTCAAGGGTTGTTAAAGTTTATTCCTCTTGCTGT
ATGGTCTTTTATCACATGTTTTTTATACGAGTTAAAAGGTGGCAGCGAATTCCATAGTCTTTTTTGGTATTTTGCTTGCA
TAATGTCTGCAAATTTCGTGCAAGCATTTGTGATTTTGCCACTACTCATGTGGTATAAAGGTATATCACCAATTCAAACG
ATGAAAGGTGTTATGCCAGCACTTACACTTGCGTTTTTTTCTAAATCATCTAGTGCAACGCTGCCTACAACCATAGACTG
TGTGCAAAATCAGCTAAAAGTGCCAAAGAAATTGTCATCTTTTATTCTACCAATATGTACAACTATCAATATGAATGCGT
GTGCTGCATTTATTTTGATTACAGTGATGTTTGTTGCAGAGATGAATGGGCACACATTTTCCTTAAGTGAGATGTTCATA
TGGATTTTTTTAGCTACAGGAGCTGCAATTGGTAACGCTGGAGTGCCGATGGGGTGCTATTTTATGGCAACTAGTTATTT
GGTATCAATGAATGTTCCTTTGTACATTATGGGATTGATTTTGCCTATTTATACAATCATTGATATGTTTGAAACTGCAA
TAAATGTGTGGTCTGATATCTGTATAACGCAGATAATTAATAAAGAATTTCAAACTCAAGAATGA

Upstream 100 bases:

>100_bases
ATTAATAATAAAATGTTACTCATCTTTACTTAACCTGTAAAGTTATCTTAACCTAATTTCAAAAATTATTGTATAATATC
ATTTTGAGGTTTTATTTTCA

Downstream 100 bases:

>100_bases
TATTAGATAATACAATAATAAAAGAATTTGAAGAGGTTGGTGCGATTTTGCACGGACATTTTGTACTCTCGTCAGGGCTG
CACAGCAACACTTACATACA

Product: sodium/glutamate symporter family protein, putative

Products: L-aspartate [Cytoplasm]; Proton [Cytoplasm]; L-glutamate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MRKLAILFSILFAVIAYYLNNEVIFEIAKLFSDIFISLLKLISLPLVFLSIVSTISGLKDSIEIKVLLKKTLFYTLFTTI
VAAFVALSFYLFIDPVRKNFISNTIESVSDSNHNYFSYLKSLIPSNFVQVFLENNVIGSILIAFLMGGAIISLSKEKQDI
LHQIFSALFDTLLKIAQGLLKFIPLAVWSFITCFLYELKGGSEFHSLFWYFACIMSANFVQAFVILPLLMWYKGISPIQT
MKGVMPALTLAFFSKSSSATLPTTIDCVQNQLKVPKKLSSFILPICTTINMNACAAFILITVMFVAEMNGHTFSLSEMFI
WIFLATGAAIGNAGVPMGCYFMATSYLVSMNVPLYIMGLILPIYTIIDMFETAINVWSDICITQIINKEFQTQE

Sequences:

>Translated_394_residues
MRKLAILFSILFAVIAYYLNNEVIFEIAKLFSDIFISLLKLISLPLVFLSIVSTISGLKDSIEIKVLLKKTLFYTLFTTI
VAAFVALSFYLFIDPVRKNFISNTIESVSDSNHNYFSYLKSLIPSNFVQVFLENNVIGSILIAFLMGGAIISLSKEKQDI
LHQIFSALFDTLLKIAQGLLKFIPLAVWSFITCFLYELKGGSEFHSLFWYFACIMSANFVQAFVILPLLMWYKGISPIQT
MKGVMPALTLAFFSKSSSATLPTTIDCVQNQLKVPKKLSSFILPICTTINMNACAAFILITVMFVAEMNGHTFSLSEMFI
WIFLATGAAIGNAGVPMGCYFMATSYLVSMNVPLYIMGLILPIYTIIDMFETAINVWSDICITQIINKEFQTQE
>Mature_394_residues
MRKLAILFSILFAVIAYYLNNEVIFEIAKLFSDIFISLLKLISLPLVFLSIVSTISGLKDSIEIKVLLKKTLFYTLFTTI
VAAFVALSFYLFIDPVRKNFISNTIESVSDSNHNYFSYLKSLIPSNFVQVFLENNVIGSILIAFLMGGAIISLSKEKQDI
LHQIFSALFDTLLKIAQGLLKFIPLAVWSFITCFLYELKGGSEFHSLFWYFACIMSANFVQAFVILPLLMWYKGISPIQT
MKGVMPALTLAFFSKSSSATLPTTIDCVQNQLKVPKKLSSFILPICTTINMNACAAFILITVMFVAEMNGHTFSLSEMFI
WIFLATGAAIGNAGVPMGCYFMATSYLVSMNVPLYIMGLILPIYTIIDMFETAINVWSDICITQIINKEFQTQE

Specific function: This Carrier Protein Is Part Of The Na(+)-Independent, Binding-Protein-Independent Glutamate-Aspartate Transport System. [C]

COG id: COG1301

COG function: function code C; Na+/H+-dicarboxylate symporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:dicarboxylate (SDF) symporter (TC 2.A.23) family [H]

Homologues:

Organism=Homo sapiens, GI66773030, Length=256, Percent_Identity=32.03125, Blast_Score=121, Evalue=1e-27,
Organism=Homo sapiens, GI21314632, Length=391, Percent_Identity=24.0409207161125, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI4827012, Length=259, Percent_Identity=26.2548262548263, Blast_Score=104, Evalue=1e-22,
Organism=Homo sapiens, GI223468566, Length=247, Percent_Identity=26.7206477732794, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI223468564, Length=247, Percent_Identity=26.7206477732794, Blast_Score=103, Evalue=3e-22,
Organism=Homo sapiens, GI5032093, Length=295, Percent_Identity=26.1016949152542, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI169790839, Length=294, Percent_Identity=26.1904761904762, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI194239697, Length=227, Percent_Identity=27.3127753303965, Blast_Score=94, Evalue=3e-19,
Organism=Homo sapiens, GI40254478, Length=408, Percent_Identity=22.3039215686275, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI301601644, Length=122, Percent_Identity=34.4262295081967, Blast_Score=86, Evalue=9e-17,
Organism=Homo sapiens, GI262359914, Length=164, Percent_Identity=27.4390243902439, Blast_Score=74, Evalue=3e-13,
Organism=Escherichia coli, GI1790514, Length=401, Percent_Identity=23.9401496259352, Blast_Score=109, Evalue=3e-25,
Organism=Escherichia coli, GI1788024, Length=387, Percent_Identity=26.3565891472868, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI1789473, Length=380, Percent_Identity=23.4210526315789, Blast_Score=65, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI71996953, Length=414, Percent_Identity=23.1884057971014, Blast_Score=125, Evalue=4e-29,
Organism=Caenorhabditis elegans, GI193206505, Length=402, Percent_Identity=24.6268656716418, Blast_Score=120, Evalue=9e-28,
Organism=Caenorhabditis elegans, GI193206654, Length=407, Percent_Identity=26.5356265356265, Blast_Score=113, Evalue=1e-25,
Organism=Caenorhabditis elegans, GI71983106, Length=398, Percent_Identity=23.8693467336683, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI71983099, Length=398, Percent_Identity=23.8693467336683, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17537407, Length=390, Percent_Identity=24.1025641025641, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI17541374, Length=395, Percent_Identity=23.5443037974684, Blast_Score=93, Evalue=3e-19,
Organism=Drosophila melanogaster, GI24583025, Length=395, Percent_Identity=25.0632911392405, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI17137668, Length=395, Percent_Identity=25.0632911392405, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI24583023, Length=395, Percent_Identity=25.0632911392405, Blast_Score=115, Evalue=8e-26,
Organism=Drosophila melanogaster, GI281360483, Length=421, Percent_Identity=20.6650831353919, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI17137666, Length=421, Percent_Identity=20.6650831353919, Blast_Score=72, Evalue=7e-13,
Organism=Drosophila melanogaster, GI281360481, Length=421, Percent_Identity=20.6650831353919, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001991 [H]

Pfam domain/function: PF00375 SDF [H]

EC number: NA

Molecular weight: Translated: 44200; Mature: 44200

Theoretical pI: Translated: 7.74; Mature: 7.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate [Periplasm]; Proton [Periplasm]; L-glutamate [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-aspartate [Periplasm] = Proton [Cytoplasm] + L-aspartate [Cytoplasm] Proton [Periplasm] + L-glutamate [Periplasm] = Proton [Cytoplasm] + L-glutamate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]