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The map label for this gene is pyrE [H]

Identifier: 190570891

GI number: 190570891

Start: 507483

End: 508073

Strand: Reverse

Name: pyrE [H]

Synonym: WPa_0470

Alternate gene names: 190570891

Gene position: 508073-507483 (Counterclockwise)

Preceding gene: 190570892

Following gene: 190570889

Centisome position: 34.27

GC content: 34.52

Gene sequence:

>591_bases
ATGATATTAGATAATACAATAATAAAAGAATTTGAAGAGGTTGGTGCGATTTTGCACGGACATTTTGTACTCTCGTCAGG
GCTGCACAGCAACACTTACATACAATGCGCTAAAATTTTTGAAAATCCAAGCAGAGCAATGAACGTTTGTGAGCTATTGG
CGAATAAAATAAGAAAAGAGCTTATTGAACCCATAGATTTAATACTATCTCCTGCGATTGGTGGAATAATCGTGGGTTAT
GAGATTGGTAGACAGCTTGGAATCCGAACAATATTTTGCGAACGTGTTAATGGTAAATTTGAATTACGCCGTGGATTTGA
GATTAAACAAGGTGAGAAAATCTTACTAATTGAAGATGTGATTACCACAGGTAAATCTTCACTTGAAGCAGTAAAATGTG
GAGAAGAGAAGGGAGGTAAAGTTGTTGCTGAAGCTTCTTTGATAAAGAGAAGTAGTGAGACAAAACTACCTTTTTCTGTT
ATATCTTTGATTGAACTAAACATTCAAAACTATAGCGAGAAAGAACTGCCAAGTGAATTAAAACAATTACCTATAATGAA
ACCTGGAAGTAGAGAATATTTAACAAAGTAA

Upstream 100 bases:

>100_bases
TGCCTATTTATACAATCATTGATATGTTTGAAACTGCAATAAATGTGTGGTCTGATATCTGTATAACGCAGATAATTAAT
AAAGAATTTCAAACTCAAGA

Downstream 100 bases:

>100_bases
TTCTATATAGTATATTTTCTCTTGGTTTAGCTAAGGGTTTTATGGGTTTTTGAAATTTTGCCCATAAAACCCCTTTCATG
ATTAAAAATACACTAAATCT

Product: orotate phosphoribosyltransferase

Products: NA

Alternate protein names: OPRT; OPRTase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MILDNTIIKEFEEVGAILHGHFVLSSGLHSNTYIQCAKIFENPSRAMNVCELLANKIRKELIEPIDLILSPAIGGIIVGY
EIGRQLGIRTIFCERVNGKFELRRGFEIKQGEKILLIEDVITTGKSSLEAVKCGEEKGGKVVAEASLIKRSSETKLPFSV
ISLIELNIQNYSEKELPSELKQLPIMKPGSREYLTK

Sequences:

>Translated_196_residues
MILDNTIIKEFEEVGAILHGHFVLSSGLHSNTYIQCAKIFENPSRAMNVCELLANKIRKELIEPIDLILSPAIGGIIVGY
EIGRQLGIRTIFCERVNGKFELRRGFEIKQGEKILLIEDVITTGKSSLEAVKCGEEKGGKVVAEASLIKRSSETKLPFSV
ISLIELNIQNYSEKELPSELKQLPIMKPGSREYLTK
>Mature_196_residues
MILDNTIIKEFEEVGAILHGHFVLSSGLHSNTYIQCAKIFENPSRAMNVCELLANKIRKELIEPIDLILSPAIGGIIVGY
EIGRQLGIRTIFCERVNGKFELRRGFEIKQGEKILLIEDVITTGKSSLEAVKCGEEKGGKVVAEASLIKRSSETKLPFSV
ISLIELNIQNYSEKELPSELKQLPIMKPGSREYLTK

Specific function: Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) [H]

COG id: COG0461

COG function: function code F; Orotate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023031
- InterPro:   IPR006273
- InterPro:   IPR000836 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.10 [H]

Molecular weight: Translated: 21857; Mature: 21857

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MILDNTIIKEFEEVGAILHGHFVLSSGLHSNTYIQCAKIFENPSRAMNVCELLANKIRKE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LIEPIDLILSPAIGGIIVGYEIGRQLGIRTIFCERVNGKFELRRGFEIKQGEKILLIEDV
HHHHHHHHHHHCCCCEEEHHHHHHHHCHHHEEEECCCCEEEECCCCCCCCCCEEEEEHHH
ITTGKSSLEAVKCGEEKGGKVVAEASLIKRSSETKLPFSVISLIELNIQNYSEKELPSEL
HHCCCHHHHHHHCCCCCCCEEEEHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
KQLPIMKPGSREYLTK
HHCCCCCCCCHHCCCC
>Mature Secondary Structure
MILDNTIIKEFEEVGAILHGHFVLSSGLHSNTYIQCAKIFENPSRAMNVCELLANKIRKE
CCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
LIEPIDLILSPAIGGIIVGYEIGRQLGIRTIFCERVNGKFELRRGFEIKQGEKILLIEDV
HHHHHHHHHHHCCCCEEEHHHHHHHHCHHHEEEECCCCEEEECCCCCCCCCCEEEEEHHH
ITTGKSSLEAVKCGEEKGGKVVAEASLIKRSSETKLPFSVISLIELNIQNYSEKELPSEL
HHCCCHHHHHHHCCCCCCCEEEEHHHHHHCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHH
KQLPIMKPGSREYLTK
HHCCCCCCCCHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA