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The map label for this gene is ugd [H]

Identifier: 189352377

GI number: 189352377

Start: 431990

End: 433402

Strand: Direct

Name: ugd [H]

Synonym: BMULJ_03596

Alternate gene names: 189352377

Gene position: 431990-433402 (Clockwise)

Preceding gene: 189352376

Following gene: 189352378

Centisome position: 17.47

GC content: 69.07

Gene sequence:

>1413_bases
ATGAATCTGACTATCATCGGCAGCGGTTACGTAGGTCTGGTCACGGGCGCCTGTCTCGCCGACATCGGCCACGACGTGTT
CTGTCTCGACGTCGACCAGGCGAAGATCGACGTGCTCAACGACGGCGGCGTGCCGATCCACGAGCCGGGCCTGAAGGAAG
TGATCGCGCGCAACCGCGCGGCCGGCCGCCTGCGTTTCTCGACCGACGTCGAGGCGGCCGTCGCGCACGGCGACGTGCAG
TTCATCGCGGTCGGCACGCCGCCCGACGAGGACGGCTCGGCCGATCTGCAGTACGTGCTCGCGGCCGCGCGCAACATCGG
CCGCTACATGAAGGGCTTCAAGGTGATCGTCGACAAGTCGACGGTGCCGGTCGGCACGGCGGAACGCGTGCGCGCGGCGG
TCGCGGAAGAGCTCGCGAAGCGCGGCGACGATTCGATGTTCTCGGTCGTGTCGAATCCGGAGTTCCTGAAGGAGGGCGCG
GCGGTCGACGACTTCACGCGGCCCGACCGCATCGTGATCGGCTGCGACGACGACGTGCCGGGCGAGCGCGCGCGCGAGCT
GATGAAGAAGCTGTATGCGCCGTTCAACCGCAATCACGAACGCACGCTCTACATGGACGTGCGCTCGGCCGAGTTCACGA
AGTACGCGGCCAACGCGATGCTCGCGACGCGCATCTCGTTCATGAACGAGCTCGCGAACCTCGCGGACCGCTTCGGCGCC
GACATCGAATCGGTGCGGCGCGGGATCGGCTCCGATCCGCGCATCGGCTATCACTTCCTCTATGCCGGCTGCGGCTACGG
CGGCTCGTGCTTCCCGAAGGACGTCGAGGCGCTGATCCGCACGGCCGACGAACACGGGCACACGCTGCAGATCCTGAAGG
CCGTGTCGTCGGTGAACGCCGCGCAAAAGCGCGTGCTCGCCGAGAAGATCGTCGCGCGCTTCGGCGAGGATCTGACGGGC
CGCACGTTCGGCCTCTGGGGGCTCGCGTTCAAGCCGAACACCGACGACATGCGCGAGGCGCCGAGCCGCGAGCTGATCGC
CGAGCTGCTGTCGCGCGGCGCGCGCGTCGCCGCGTACGACCCGGTCGCGCAGCGCGAGGCGCGCCGCGTGCTCGCGCTCG
ATCTCGCCGATCGTCCGGCGTGGCTCGAACGGCTCAGCTTCGTCGACGACGAGGCGCAGGCCGCGCGCGATGCCGATGCG
CTCGTGATCGTCACCGAATGGAAGGCATTCAAGAGCCCCGATTTCGCGGCGCTCGGCCGGCTGTGGAAAGCACCCGTGAT
CTTCGACGGCCGCAACCTCTACGAGCCCGACACGATGAGCGAGCACGGCATCGAGTATCACCCGATCGGCCGTCCGGGCT
CGCGGCAGGCCGTCGCCGCGCGAGCGCCCGGCGCCGCCCGCGCCAGCGCGTGA

Upstream 100 bases:

>100_bases
ACGCTGTGGAAAGGCTTCACGGGCAGCAACGCGTACTGACGCGGCGCCGCATGCGCGGCTTCACGAATTTCGAATCATTG
GTCAAGAGGTCCGACACATC

Downstream 100 bases:

>100_bases
CCGCTGCACGCGCCGTTTCCCGCTACTCGTCACGACACGCCATGTTCCGGAACATCCTGATCGTCTGTCACGCGAACGTC
TGCCGCAGCCCCGCGGCGGA

Product: UDP glucose 6-dehydrogenase

Products: NA

Alternate protein names: UDP-Glc dehydrogenase; UDP-GlcDH; UDPGDH [H]

Number of amino acids: Translated: 470; Mature: 470

Protein sequence:

>470_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDQAKIDVLNDGGVPIHEPGLKEVIARNRAAGRLRFSTDVEAAVAHGDVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRYMKGFKVIVDKSTVPVGTAERVRAAVAEELAKRGDDSMFSVVSNPEFLKEGA
AVDDFTRPDRIVIGCDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLADRFGA
DIESVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTADEHGHTLQILKAVSSVNAAQKRVLAEKIVARFGEDLTG
RTFGLWGLAFKPNTDDMREAPSRELIAELLSRGARVAAYDPVAQREARRVLALDLADRPAWLERLSFVDDEAQAARDADA
LVIVTEWKAFKSPDFAALGRLWKAPVIFDGRNLYEPDTMSEHGIEYHPIGRPGSRQAVAARAPGAARASA

Sequences:

>Translated_470_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDQAKIDVLNDGGVPIHEPGLKEVIARNRAAGRLRFSTDVEAAVAHGDVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRYMKGFKVIVDKSTVPVGTAERVRAAVAEELAKRGDDSMFSVVSNPEFLKEGA
AVDDFTRPDRIVIGCDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLADRFGA
DIESVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTADEHGHTLQILKAVSSVNAAQKRVLAEKIVARFGEDLTG
RTFGLWGLAFKPNTDDMREAPSRELIAELLSRGARVAAYDPVAQREARRVLALDLADRPAWLERLSFVDDEAQAARDADA
LVIVTEWKAFKSPDFAALGRLWKAPVIFDGRNLYEPDTMSEHGIEYHPIGRPGSRQAVAARAPGAARASA
>Mature_470_residues
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDQAKIDVLNDGGVPIHEPGLKEVIARNRAAGRLRFSTDVEAAVAHGDVQ
FIAVGTPPDEDGSADLQYVLAAARNIGRYMKGFKVIVDKSTVPVGTAERVRAAVAEELAKRGDDSMFSVVSNPEFLKEGA
AVDDFTRPDRIVIGCDDDVPGERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLADRFGA
DIESVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTADEHGHTLQILKAVSSVNAAQKRVLAEKIVARFGEDLTG
RTFGLWGLAFKPNTDDMREAPSRELIAELLSRGARVAAYDPVAQREARRVLALDLADRPAWLERLSFVDDEAQAARDADA
LVIVTEWKAFKSPDFAALGRLWKAPVIFDGRNLYEPDTMSEHGIEYHPIGRPGSRQAVAARAPGAARASA

Specific function: Unknown

COG id: COG1004

COG function: function code M; Predicted UDP-glucose 6-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the UDP-glucose/GDP-mannose dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI4507813, Length=475, Percent_Identity=35.1578947368421, Blast_Score=255, Evalue=5e-68,
Organism=Homo sapiens, GI296040438, Length=378, Percent_Identity=34.9206349206349, Blast_Score=201, Evalue=9e-52,
Organism=Homo sapiens, GI296040443, Length=331, Percent_Identity=34.7432024169184, Blast_Score=176, Evalue=4e-44,
Organism=Escherichia coli, GI1788340, Length=373, Percent_Identity=29.4906166219839, Blast_Score=157, Evalue=2e-39,
Organism=Escherichia coli, GI48994968, Length=435, Percent_Identity=30.5747126436782, Blast_Score=136, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17560350, Length=467, Percent_Identity=35.9743040685225, Blast_Score=260, Evalue=1e-69,
Organism=Drosophila melanogaster, GI17136908, Length=472, Percent_Identity=34.7457627118644, Blast_Score=251, Evalue=8e-67,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR021157
- InterPro:   IPR016040
- InterPro:   IPR017476
- InterPro:   IPR014027
- InterPro:   IPR014026
- InterPro:   IPR014028
- InterPro:   IPR001732 [H]

Pfam domain/function: PF00984 UDPG_MGDP_dh; PF03720 UDPG_MGDP_dh_C; PF03721 UDPG_MGDP_dh_N [H]

EC number: =1.1.1.22 [H]

Molecular weight: Translated: 51178; Mature: 51178

Theoretical pI: Translated: 5.72; Mature: 5.72

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDQAKIDVLNDGGVPIHEPGLKEVIARNRA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHCCCC
AGRLRFSTDVEAAVAHGDVQFIAVGTPPDEDGSADLQYVLAAARNIGRYMKGFKVIVDKS
CCEEEECCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECC
TVPVGTAERVRAAVAEELAKRGDDSMFSVVSNPEFLKEGAAVDDFTRPDRIVIGCDDDVP
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHCCCCCCCCCCCCEEEEECCCCCC
GERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLADRFGA
HHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIESVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTADEHGHTLQILKAVSSVNA
CHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AQKRVLAEKIVARFGEDLTGRTFGLWGLAFKPNTDDMREAPSRELIAELLSRGARVAAYD
HHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCCHHHHHHHHHCCCEEEECC
PVAQREARRVLALDLADRPAWLERLSFVDDEAQAARDADALVIVTEWKAFKSPDFAALGR
CHHHHHHHHEEEEECCCCHHHHHHHHHCCCHHHHHCCCCEEEEEEECCCCCCCCHHHHHH
LWKAPVIFDGRNLYEPDTMSEHGIEYHPIGRPGSRQAVAARAPGAARASA
HHCCCEEECCCCCCCCCCCCCCCCEECCCCCCCCCCEEEECCCCCCCCCC
>Mature Secondary Structure
MNLTIIGSGYVGLVTGACLADIGHDVFCLDVDQAKIDVLNDGGVPIHEPGLKEVIARNRA
CEEEEEECCHHHHHHHHHHHHCCCCEEEEECCCCEEEEECCCCCCCCCCCHHHHHHCCCC
AGRLRFSTDVEAAVAHGDVQFIAVGTPPDEDGSADLQYVLAAARNIGRYMKGFKVIVDKS
CCEEEECCCHHHHHCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCEEEEEECC
TVPVGTAERVRAAVAEELAKRGDDSMFSVVSNPEFLKEGAAVDDFTRPDRIVIGCDDDVP
CCCCCCHHHHHHHHHHHHHHCCCCCHHHHHCCHHHHHCCCCCCCCCCCCEEEEECCCCCC
GERARELMKKLYAPFNRNHERTLYMDVRSAEFTKYAANAMLATRISFMNELANLADRFGA
HHHHHHHHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
DIESVRRGIGSDPRIGYHFLYAGCGYGGSCFPKDVEALIRTADEHGHTLQILKAVSSVNA
CHHHHHHCCCCCCCCCEEEEEEECCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AQKRVLAEKIVARFGEDLTGRTFGLWGLAFKPNTDDMREAPSRELIAELLSRGARVAAYD
HHHHHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCHHHHCCCHHHHHHHHHCCCEEEECC
PVAQREARRVLALDLADRPAWLERLSFVDDEAQAARDADALVIVTEWKAFKSPDFAALGR
CHHHHHHHHEEEEECCCCHHHHHHHHHCCCHHHHHCCCCEEEEEEECCCCCCCCHHHHHH
LWKAPVIFDGRNLYEPDTMSEHGIEYHPIGRPGSRQAVAARAPGAARASA
HHCCCEEECCCCCCCCCCCCCCCCEECCCCCCCCCCEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]