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The map label for this gene is ptpA [H]

Identifier: 189352378

GI number: 189352378

Start: 433444

End: 433887

Strand: Direct

Name: ptpA [H]

Synonym: BMULJ_03597

Alternate gene names: 189352378

Gene position: 433444-433887 (Clockwise)

Preceding gene: 189352377

Following gene: 189352379

Centisome position: 17.53

GC content: 66.67

Gene sequence:

>444_bases
ATGTTCCGGAACATCCTGATCGTCTGTCACGCGAACGTCTGCCGCAGCCCCGCGGCGGAAATGCTGTTCAAGTCGCACGC
CGCCTCGCGCGGCGGGCCGCGTGCGACGTTTCATTCGGCTGGCGTTCGCGCGAACGACGGCGACGGCATCGATCCGGTGA
TGCGGCGGCTGCTCGCCGAGCGCGGCGTCGATGCGACGACGCACCGATCGCGGCGGCTGTCGCGCCGCATCGTGCGCGAC
GCGGACCTGATCCTCGTCAGCGAGCGTGCGCAGATCGCGGCCGTGGAAGCGATCGACCCGTTCGCGCGCGGCAAGGTTCA
TCTGCTCGGCAAGTGGGAAGACGCCGAGATCGCCGATCCGCATGGCGGCCCCGAGGCCGACTATCGCGAGAGCTACTCAT
TGATCGAACGTCTGGTTCAAGGATGGCTGCAAAAACTATGCTGA

Upstream 100 bases:

>100_bases
CGGGCTCGCGGCAGGCCGTCGCCGCGCGAGCGCCCGGCGCCGCCCGCGCCAGCGCGTGACCGCTGCACGCGCCGTTTCCC
GCTACTCGTCACGACACGCC

Downstream 100 bases:

>100_bases
AACGCTCGATGCGCCCGGTGGCGCTTGCCGTCGCGCTGACGACTTTCCTGTCTGCGTGCGCGACCGCCCCCGGCAACTAC
CTCGACTCGTCGAACCTGAA

Product: protein-tyrosine phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 147; Mature: 147

Protein sequence:

>147_residues
MFRNILIVCHANVCRSPAAEMLFKSHAASRGGPRATFHSAGVRANDGDGIDPVMRRLLAERGVDATTHRSRRLSRRIVRD
ADLILVSERAQIAAVEAIDPFARGKVHLLGKWEDAEIADPHGGPEADYRESYSLIERLVQGWLQKLC

Sequences:

>Translated_147_residues
MFRNILIVCHANVCRSPAAEMLFKSHAASRGGPRATFHSAGVRANDGDGIDPVMRRLLAERGVDATTHRSRRLSRRIVRD
ADLILVSERAQIAAVEAIDPFARGKVHLLGKWEDAEIADPHGGPEADYRESYSLIERLVQGWLQKLC
>Mature_147_residues
MFRNILIVCHANVCRSPAAEMLFKSHAASRGGPRATFHSAGVRANDGDGIDPVMRRLLAERGVDATTHRSRRLSRRIVRD
ADLILVSERAQIAAVEAIDPFARGKVHLLGKWEDAEIADPHGGPEADYRESYSLIERLVQGWLQKLC

Specific function: Dephosphorylates ptk. May be involved in the production and the transport of exopolysaccharides [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Escherichia coli, GI1788375, Length=147, Percent_Identity=39.4557823129252, Blast_Score=102, Evalue=9e-24,
Organism=Escherichia coli, GI87081812, Length=146, Percent_Identity=36.3013698630137, Blast_Score=87, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16324; Mature: 16324

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFRNILIVCHANVCRSPAAEMLFKSHAASRGGPRATFHSAGVRANDGDGIDPVMRRLLAE
CCCCEEEEEECHHHCCHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHH
RGVDATTHRSRRLSRRIVRDADLILVSERAQIAAVEAIDPFARGKVHLLGKWEDAEIADP
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCHHHCCCEEEEECCCCCCCCCC
HGGPEADYRESYSLIERLVQGWLQKLC
CCCCCCHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MFRNILIVCHANVCRSPAAEMLFKSHAASRGGPRATFHSAGVRANDGDGIDPVMRRLLAE
CCCCEEEEEECHHHCCHHHHHHHHHHHCCCCCCCCCHHCCCCCCCCCCCHHHHHHHHHHH
RGVDATTHRSRRLSRRIVRDADLILVSERAQIAAVEAIDPFARGKVHLLGKWEDAEIADP
CCCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCHHHCCCEEEEECCCCCCCCCC
HGGPEADYRESYSLIERLVQGWLQKLC
CCCCCCHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9434192; 9571056 [H]