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The map label for this gene is ftsI [H]

Identifier: 189184782

GI number: 189184782

Start: 1915328

End: 1917079

Strand: Reverse

Name: ftsI [H]

Synonym: OTT_1875

Alternate gene names: 189184782

Gene position: 1917079-1915328 (Counterclockwise)

Preceding gene: 189184783

Following gene: 189184781

Centisome position: 95.43

GC content: 29.05

Gene sequence:

>1752_bases
ATGTTAAAAGCATTATTTAATAGCATCTTTAAAACGCTTGTTGAATTACTCAGGACAGCTAGTTTTAATATTAATTATTT
ATTCTTTTCTAATCAGCCTAATTTAACGTTAAGAATTAGAATATTATTTGTAATATTAAGCTTTTTAGTTGCTTTTCTGG
TTGTTGCCTTTAGAATTATCAAGCTTTCTACTTACAATTCTCAATATTCACACTGTAGCAGAAACATGCATTTTAAGCAT
AGAAAGGAAATTGTTGATAGAAACAATAATATATTAGCAGTAAACCTATTTGCTCCCTCAATCATAGCCCGGACAAAAAA
AATTAGTTCTCCTGAAGGATTAGTAAAACAATTGCAATATGTTTTTACTGATATTAATGGAGATAAGCTTTTAAATGCTC
TAAAAAATAATAAAAATTTTGTTGTAGTAAAACGTCATCTTACTCCTACTCAACATAAACAAGTGTATGATTTAGGAATT
CCTGGCTTAGATTTTGAAGAAGATTACAAAAGAGTTTATACATATGGAAATCTGTTATCTCATGTACTAGGTTATGTTAG
TACCGATATGCGTGGTTTAGCAGGAATAGAGAACTATTATCATAACTATCTATCTAATAATGATGCTCAATTAAAAGAAG
CAGAGTTAAATAAACCTCTAGTGCTAAGCATTGACATTAGAATACAAGACATAGTAAGCAAAGAACTAGATAAGATAATT
AAAGATTTTAATGCTATAGGCGGAGTAGGAATAATAGCTGATCCAAATAATGGTGAGATATTAGCTCTAGTTAGCAAACC
AGATTTTGATCCTCATTACCCAGCTAAAGCAGTTGGAAGACAATTATTTAATAAAGCAAGTCTAGGAGTTTATGAACTTG
GTTCTGTGATGCATGCTTTAACTATTGCTATCGGTTTAGATACTCAAACTATAACTCTAAACAATACTTATGACCTTACA
GATTTTAAAATTGATAATTTTAGAATCAAAGATTATAAAAATTTTGTAGGATATTATAGTGTTCCGGAAATTTTTATGTA
TTCTTCTAATATTGGTATTGTCCAAATTGGATTAGATATTGGACAATTTAACTTAAAGAAATACTTCAAATTGCTAGCTC
TAGATAAGACATTAAAAATAGAACTACCAGAAAAAGCAAATTCATTGTATCATGCTAATACATCCTGGAATAATATTACA
ACAGCAACAATATCTTATGGTTATGGTATATCTATTAGTCCATTACATTTTGTTCAGGCAATGATTCCTATTGTTAATGG
AGGAAATTTGTATCCTATTACTCTAATTAAAAGAACGCCTAATGATAATCTTATAGCCCAAAAAATATTTAGTAGTAAAA
CATCAAAAGAACTTAATAGTTTATTGCGTTTAGCAGTTAAACATGGTACTAGTAAAAACAGTGATGTAGTTGGATATCTT
GTTGGCGGAAAGGTTGGTACCGCCAAAAAAATTAAAGATAGAAAATATGATAAAAATAGTATAAGGTCATCTTTTATTGG
TATTTATCCATCGATAGCACCTAAATTTATTATATATTTAATGCTTGATGAGCCTAAAAGCAATAATTCAACTTATGAAT
TGACTAATGCGGCTGAACATGGCATTACTTCAGCTGCAGCTAAAATTATTTCTAAAATAGGTACGCTATATGGTATACAA
CCATATCATACAGAAATGACTAGTGTTCAGAATCTTAAAACCAATAACAACTCTCAGCATGGAATCAAATAA

Upstream 100 bases:

>100_bases
AATAGTTTAAAAATTTGAAAGAAAAATATATTAGCTATTTACTATGCCTCACAGAATGTTGCATCATTAGCAAATCAAGC
TATATAACTACTAACTAGAA

Downstream 100 bases:

>100_bases
TATCATTGAAATTATTAAAAAGCTAAATATAAGAAATATTGCTATAACAGCTCAATCAGCAAAACCTAATCAAATATTTT
TTGCATTACCAGGAATATCA

Product: penicillin-binding protein PbpA2

Products: NA

Alternate protein names: Sporulation-specific penicillin-binding protein [H]

Number of amino acids: Translated: 583; Mature: 583

Protein sequence:

>583_residues
MLKALFNSIFKTLVELLRTASFNINYLFFSNQPNLTLRIRILFVILSFLVAFLVVAFRIIKLSTYNSQYSHCSRNMHFKH
RKEIVDRNNNILAVNLFAPSIIARTKKISSPEGLVKQLQYVFTDINGDKLLNALKNNKNFVVVKRHLTPTQHKQVYDLGI
PGLDFEEDYKRVYTYGNLLSHVLGYVSTDMRGLAGIENYYHNYLSNNDAQLKEAELNKPLVLSIDIRIQDIVSKELDKII
KDFNAIGGVGIIADPNNGEILALVSKPDFDPHYPAKAVGRQLFNKASLGVYELGSVMHALTIAIGLDTQTITLNNTYDLT
DFKIDNFRIKDYKNFVGYYSVPEIFMYSSNIGIVQIGLDIGQFNLKKYFKLLALDKTLKIELPEKANSLYHANTSWNNIT
TATISYGYGISISPLHFVQAMIPIVNGGNLYPITLIKRTPNDNLIAQKIFSSKTSKELNSLLRLAVKHGTSKNSDVVGYL
VGGKVGTAKKIKDRKYDKNSIRSSFIGIYPSIAPKFIIYLMLDEPKSNNSTYELTNAAEHGITSAAAKIISKIGTLYGIQ
PYHTEMTSVQNLKTNNNSQHGIK

Sequences:

>Translated_583_residues
MLKALFNSIFKTLVELLRTASFNINYLFFSNQPNLTLRIRILFVILSFLVAFLVVAFRIIKLSTYNSQYSHCSRNMHFKH
RKEIVDRNNNILAVNLFAPSIIARTKKISSPEGLVKQLQYVFTDINGDKLLNALKNNKNFVVVKRHLTPTQHKQVYDLGI
PGLDFEEDYKRVYTYGNLLSHVLGYVSTDMRGLAGIENYYHNYLSNNDAQLKEAELNKPLVLSIDIRIQDIVSKELDKII
KDFNAIGGVGIIADPNNGEILALVSKPDFDPHYPAKAVGRQLFNKASLGVYELGSVMHALTIAIGLDTQTITLNNTYDLT
DFKIDNFRIKDYKNFVGYYSVPEIFMYSSNIGIVQIGLDIGQFNLKKYFKLLALDKTLKIELPEKANSLYHANTSWNNIT
TATISYGYGISISPLHFVQAMIPIVNGGNLYPITLIKRTPNDNLIAQKIFSSKTSKELNSLLRLAVKHGTSKNSDVVGYL
VGGKVGTAKKIKDRKYDKNSIRSSFIGIYPSIAPKFIIYLMLDEPKSNNSTYELTNAAEHGITSAAAKIISKIGTLYGIQ
PYHTEMTSVQNLKTNNNSQHGIK
>Mature_583_residues
MLKALFNSIFKTLVELLRTASFNINYLFFSNQPNLTLRIRILFVILSFLVAFLVVAFRIIKLSTYNSQYSHCSRNMHFKH
RKEIVDRNNNILAVNLFAPSIIARTKKISSPEGLVKQLQYVFTDINGDKLLNALKNNKNFVVVKRHLTPTQHKQVYDLGI
PGLDFEEDYKRVYTYGNLLSHVLGYVSTDMRGLAGIENYYHNYLSNNDAQLKEAELNKPLVLSIDIRIQDIVSKELDKII
KDFNAIGGVGIIADPNNGEILALVSKPDFDPHYPAKAVGRQLFNKASLGVYELGSVMHALTIAIGLDTQTITLNNTYDLT
DFKIDNFRIKDYKNFVGYYSVPEIFMYSSNIGIVQIGLDIGQFNLKKYFKLLALDKTLKIELPEKANSLYHANTSWNNIT
TATISYGYGISISPLHFVQAMIPIVNGGNLYPITLIKRTPNDNLIAQKIFSSKTSKELNSLLRLAVKHGTSKNSDVVGYL
VGGKVGTAKKIKDRKYDKNSIRSSFIGIYPSIAPKFIIYLMLDEPKSNNSTYELTNAAEHGITSAAAKIISKIGTLYGIQ
PYHTEMTSVQNLKTNNNSQHGIK

Specific function: Penicillin-binding protein with an unknown catalytic activity. May have a specialized role in the morphogenesis of spore cortex, which is a modified form of peptidoglycan. Pore cortex formation is determined primarily by the mother cell [H]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PASTA domain [H]

Homologues:

Organism=Escherichia coli, GI1786272, Length=473, Percent_Identity=23.4672304439746, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1786854, Length=416, Percent_Identity=22.8365384615385, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005543
- InterPro:   IPR005311
- InterPro:   IPR001460
- InterPro:   IPR011927 [H]

Pfam domain/function: PF03793 PASTA; PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 65581; Mature: 65581

Theoretical pI: Translated: 9.95; Mature: 9.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKALFNSIFKTLVELLRTASFNINYLFFSNQPNLTLRIRILFVILSFLVAFLVVAFRII
CHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
KLSTYNSQYSHCSRNMHFKHRKEIVDRNNNILAVNLFAPSIIARTKKISSPEGLVKQLQY
HHCCCCCHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCHHHHHHHHHH
VFTDINGDKLLNALKNNKNFVVVKRHLTPTQHKQVYDLGIPGLDFEEDYKRVYTYGNLLS
HHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHH
HVLGYVSTDMRGLAGIENYYHNYLSNNDAQLKEAELNKPLVLSIDIRIQDIVSKELDKII
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEEEEHHHHHHHHHHHHH
KDFNAIGGVGIIADPNNGEILALVSKPDFDPHYPAKAVGRQLFNKASLGVYELGSVMHAL
HHHHHCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
TIAIGLDTQTITLNNTYDLTDFKIDNFRIKDYKNFVGYYSVPEIFMYSSNIGIVQIGLDI
HHEEECCCEEEEECCEEECCEEEECCEEEECHHHHCCCCCCCEEEEEECCCCEEEEECCC
GQFNLKKYFKLLALDKTLKIELPEKANSLYHANTSWNNITTATISYGYGISISPLHFVQA
CCHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCEEEEEEEECCCCCCCHHHHHHH
MIPIVNGGNLYPITLIKRTPNDNLIAQKIFSSKTSKELNSLLRLAVKHGTSKNSDVVGYL
HHHHCCCCCEEEEEEEEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCEEEEE
VGGKVGTAKKIKDRKYDKNSIRSSFIGIYPSIAPKFIIYLMLDEPKSNNSTYELTNAAEH
ECCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCEEECCHHHH
GITSAAAKIISKIGTLYGIQPYHTEMTSVQNLKTNNNSQHGIK
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure
MLKALFNSIFKTLVELLRTASFNINYLFFSNQPNLTLRIRILFVILSFLVAFLVVAFRII
CHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
KLSTYNSQYSHCSRNMHFKHRKEIVDRNNNILAVNLFAPSIIARTKKISSPEGLVKQLQY
HHCCCCCHHHHHHCCCCHHHHHHHHCCCCCEEEEEECCCHHHHHHHCCCCHHHHHHHHHH
VFTDINGDKLLNALKNNKNFVVVKRHLTPTQHKQVYDLGIPGLDFEEDYKRVYTYGNLLS
HHHCCCHHHHHHHHHCCCCEEEEEECCCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHH
HVLGYVSTDMRGLAGIENYYHNYLSNNDAQLKEAELNKPLVLSIDIRIQDIVSKELDKII
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHCCCCEEEEEEEEHHHHHHHHHHHHH
KDFNAIGGVGIIADPNNGEILALVSKPDFDPHYPAKAVGRQLFNKASLGVYELGSVMHAL
HHHHHCCCEEEEECCCCCCEEEEEECCCCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHH
TIAIGLDTQTITLNNTYDLTDFKIDNFRIKDYKNFVGYYSVPEIFMYSSNIGIVQIGLDI
HHEEECCCEEEEECCEEECCEEEECCEEEECHHHHCCCCCCCEEEEEECCCCEEEEECCC
GQFNLKKYFKLLALDKTLKIELPEKANSLYHANTSWNNITTATISYGYGISISPLHFVQA
CCHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCCCCCEEEEEEEECCCCCCCHHHHHHH
MIPIVNGGNLYPITLIKRTPNDNLIAQKIFSSKTSKELNSLLRLAVKHGTSKNSDVVGYL
HHHHCCCCCEEEEEEEEECCCCCHHHHHHHHCHHHHHHHHHHHHHHHCCCCCCCCEEEEE
VGGKVGTAKKIKDRKYDKNSIRSSFIGIYPSIAPKFIIYLMLDEPKSNNSTYELTNAAEH
ECCCCCCHHHHHCCCCCHHHHHHHHHHCCCCCCCEEEEEEEEECCCCCCCCEEECCHHHH
GITSAAAKIISKIGTLYGIQPYHTEMTSVQNLKTNNNSQHGIK
CHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8289242; 9384377; 8244929; 8436954 [H]