Click here to switch to the map view.

The map label for this gene is murG [H]

Identifier: 189183582

GI number: 189183582

Start: 703818

End: 704897

Strand: Direct

Name: murG [H]

Synonym: OTT_0675

Alternate gene names: 189183582

Gene position: 703818-704897 (Clockwise)

Preceding gene: 189183581

Following gene: 189183583

Centisome position: 35.03

GC content: 30.65

Gene sequence:

>1080_bases
ATGAAAACAATATTTTTAGTTGGAGGTGGAACAGGTGGGCACTTATTTCCAGCGATTGCATTAGGAGAAGAATTACAGGA
GCGTGGTTATAATGTATACTTGATTACAGACACTAGGTGCGAAAAATATCTCTTAAATTCTAATTATAGTTTTAAAATCC
ATATTATGAATATGGTATCCATTTCTAATACAGGGATTAAAAAACTTTATGCCTATATAAGAATATTAGCTGCTTGTATA
ACTGGATTCAAATTAGTCTACTCAAATTCTCCTGGTCTAATAGTAACTTTTGGAGGATATACTATTGCTCCTATTATTAT
AAATGGAATATTATTTAAAATTCCATTTATTCTACATGAGCAAAACAGTGTTTTAGGCCTAGCTAATAGGCTTTTCTTAA
GATATGCTAAAGCTATAACTGTAACATTTGCTAATACTCTCAATTTGAATAATCGCTATAAACATAAAGTAATAGTTACA
GGAACTCCTGTGCGAAAAGCTTTAAGATTTACACCAAAACGTAATTTTAACTCTAAAAATTTTCAGCTGTTAGTAATTGG
AGGTAGTCAAGGAACGGAAATCTTTTCTACTCTTGTGCCTAATGCAATCAAATTACTAGTCAATTGCGATCATGACTTTA
AAATTACTATTGTTCATCAGGCTGTAGCAAAGGATATTAATTACGTTAAAGCAATGTATACTGAACTAAATATAGAACAT
GAAGTGAGTGATTTTTTTTACAATATTGCTGACAAGTACAAAAATTCTCATTTAGCAATTTGCAGAGCTGGAGCATCTAC
TATATCTGAAATAATATCTTTATGTCAACCTGCAATATTAGTACCATATCCTATCTCTGCACAAAATCATCAGCTTTTTA
ATGCAAAAGCTATTGCAGATAATAAAGCTGGTTGGTGTATAGAACAAAGCACTATCACACCTCATATTTTATTTGAAAAA
ATATTTACATTAATGCAATCACCAACATTATTAGCTTCTACTGAATTGAAACTGAGAGAGATGAAAATTAATGCTGAGAA
CCTACTAGCTAATGCGGTAGAGAAATTTATAGTAACTTAG

Upstream 100 bases:

>100_bases
TGGATCTTCCAGTGTCGCAGTAGCGATAGGAGTTGGAATATTACTTGCTCTTACAAGGCATAAAACTGATCTTAGTAAAT
ATAAACTCAAGATATAAAAT

Downstream 100 bases:

>100_bases
GCCAAATTTAGATATGGCTAAGCCACTATAAAACAGTTATATTATATACTTTTTGGCCTATCTAGGTTATAGTAATAGAT
AAGCTATTATAACTGTTTTA

Product: undecaprenyldiphospho-muramoylpentapeptide beta-N- acetylglucosaminyltransferase

Products: NA

Alternate protein names: Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase [H]

Number of amino acids: Translated: 359; Mature: 359

Protein sequence:

>359_residues
MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNSNYSFKIHIMNMVSISNTGIKKLYAYIRILAACI
TGFKLVYSNSPGLIVTFGGYTIAPIIINGILFKIPFILHEQNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVT
GTPVRKALRFTPKRNFNSKNFQLLVIGGSQGTEIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEH
EVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPISAQNHQLFNAKAIADNKAGWCIEQSTITPHILFEK
IFTLMQSPTLLASTELKLREMKINAENLLANAVEKFIVT

Sequences:

>Translated_359_residues
MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNSNYSFKIHIMNMVSISNTGIKKLYAYIRILAACI
TGFKLVYSNSPGLIVTFGGYTIAPIIINGILFKIPFILHEQNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVT
GTPVRKALRFTPKRNFNSKNFQLLVIGGSQGTEIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEH
EVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPISAQNHQLFNAKAIADNKAGWCIEQSTITPHILFEK
IFTLMQSPTLLASTELKLREMKINAENLLANAVEKFIVT
>Mature_359_residues
MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNSNYSFKIHIMNMVSISNTGIKKLYAYIRILAACI
TGFKLVYSNSPGLIVTFGGYTIAPIIINGILFKIPFILHEQNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVT
GTPVRKALRFTPKRNFNSKNFQLLVIGGSQGTEIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEH
EVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPISAQNHQLFNAKAIADNKAGWCIEQSTITPHILFEK
IFTLMQSPTLLASTELKLREMKINAENLLANAVEKFIVT

Specific function: Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) [H]

COG id: COG0707

COG function: function code M; UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 28 family. MurG subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786278, Length=320, Percent_Identity=29.375, Blast_Score=138, Evalue=7e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006009
- InterPro:   IPR004276
- InterPro:   IPR007235 [H]

Pfam domain/function: PF04101 Glyco_tran_28_C; PF03033 Glyco_transf_28 [H]

EC number: =2.4.1.227 [H]

Molecular weight: Translated: 40116; Mature: 40116

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNSNYSFKIHIMNMVS
CEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCEEEEEEEEEEE
ISNTGIKKLYAYIRILAACITGFKLVYSNSPGLIVTFGGYTIAPIIINGILFKIPFILHE
ECCCCHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCEEEHHHHHHHHHHHCCEEEEC
QNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVTGTPVRKALRFTPKRNFNSKN
CCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEEEEECCCHHHHHHCCCCCCCCCCC
FQLLVIGGSQGTEIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEH
EEEEEEECCCCHHHHHHHCCHHEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCH
EVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPISAQNHQLFNAKAIAD
HHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEEEECC
NKAGWCIEQSTITPHILFEKIFTLMQSPTLLASTELKLREMKINAENLLANAVEKFIVT
CCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEECCEEEEEEECCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKTIFLVGGGTGGHLFPAIALGEELQERGYNVYLITDTRCEKYLLNSNYSFKIHIMNMVS
CEEEEEEECCCCCCHHHHHHHHHHHHHCCCEEEEEECCCCHHHHHCCCCEEEEEEEEEEE
ISNTGIKKLYAYIRILAACITGFKLVYSNSPGLIVTFGGYTIAPIIINGILFKIPFILHE
ECCCCHHHHHHHHHHHHHHHHCEEEEEECCCCEEEEECCEEEHHHHHHHHHHHCCEEEEC
QNSVLGLANRLFLRYAKAITVTFANTLNLNNRYKHKVIVTGTPVRKALRFTPKRNFNSKN
CCCHHHHHHHHHHHHHHEEEEEEEEEECCCCCEEEEEEEECCCHHHHHHCCCCCCCCCCC
FQLLVIGGSQGTEIFSTLVPNAIKLLVNCDHDFKITIVHQAVAKDINYVKAMYTELNIEH
EEEEEEECCCCHHHHHHHCCHHEEEEEECCCCEEEEEEEHHHHHHHHHHHHHHHHCCCCH
EVSDFFYNIADKYKNSHLAICRAGASTISEIISLCQPAILVPYPISAQNHQLFNAKAIAD
HHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHHHCCCCEEECCCCCCCCCEEEEEEEECC
NKAGWCIEQSTITPHILFEKIFTLMQSPTLLASTELKLREMKINAENLLANAVEKFIVT
CCCCEEEECCCCCHHHHHHHHHHHHCCCCEEEECCEEEEEEECCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA