Click here to switch to the map view.

The map label for this gene is ftsW [H]

Identifier: 189183581

GI number: 189183581

Start: 702687

End: 703814

Strand: Direct

Name: ftsW [H]

Synonym: OTT_0674

Alternate gene names: 189183581

Gene position: 702687-703814 (Clockwise)

Preceding gene: 189183580

Following gene: 189183582

Centisome position: 34.98

GC content: 31.47

Gene sequence:

>1128_bases
ATGAACTATAATTCGACTGAAAAGTTTAGAATATTATGGCGCTGGTGGAAAAGTATAGATCAATACACAGTATTTTTATT
ATGTATTTTATCTGCTTTAAGCCTAATGCTAGTAACAACATCTGGCGCTGCAGTAGCAAATAGAATAGGAGTGCCACAGT
CGTATTTTGCTAGCAAGCATATATTTTATGTTGTGCTAGCAGTAGGTACAACATTTGTTGTATCGTTTCTTAATAAAACT
ACAATAAAGCGTTTAGCTATTTTAGGATTTATTCTAAATATTATATTATTAATATTTATTAAATTTTATGGCAATCCTAT
TAAGGGAGCTAAAAGGTGGATTAATATTGGAGGAATATCATTGCAACCTTCTGAATTTGTAAAACCATTTTTTTTAGTGA
TTACTGGGTGGCTTCTTTCAGCTATTCAAAGTAATGAAATTCGCTTTATTGTTACTATTATCTTATATTTAATAGTAGCA
TTACTGCTAATTACTCAGCCTGATTTTGGTATGTTAATAACAATTTCGGTTGCATTTGGAATACAATTATTTATAGCAGG
TATACCGTTACTATGGCTCTTGATTTTGATATGTATATCAATTGCTGGAACAGCAGGAGCATATTCATTATTACCGCATG
TCAAGAGAAGAATTAATAGTTTTTTGGATCCAACCAATAGCGAAAATTACCAAGTCATGAAGTCTTTACAGGCATTTAAA
AATGGAGGGCTATATGGTAAAGGCCCAGGAGAAGGTTTAGTCAAGCACATGTTACCTGATTCTCATACTGACTTTATTTT
TGCTGTTGCTGGTGAAGAGTTAGGAGCTATAGTTTGTTTAATAATTGTAGCAATTTTTACTTTTATTGTTATATATGGAT
TTATCAAATTACTATTTGAAGAAGATAATTATACAATTTTTGTATCATCAGGTATACTTTCACAGTTTGGATTTCAGGCT
ATAGTTAATATGTGTGTTAGTACTAACCTGCTTCCAACTAAAGGCATGACTTTACCATTTATTAGTTACGGTGGATCTTC
CAGTGTCGCAGTAGCGATAGGAGTTGGAATATTACTTGCTCTTACAAGGCATAAAACTGATCTTAGTAAATATAAACTCA
AGATATAA

Upstream 100 bases:

>100_bases
TGCTCCTGCTTGCGCTTCATTTGATCAGTTTAAGAACTTTGAAGATAGGGGTAATCAATTTATAAAAATATCTCAAAAAT
TTATAACAGAATAAAAATAT

Downstream 100 bases:

>100_bases
AATATGAAAACAATATTTTTAGTTGGAGGTGGAACAGGTGGGCACTTATTTCCAGCGATTGCATTAGGAGAAGAATTACA
GGAGCGTGGTTATAATGTAT

Product: cell division protein FtsW

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 375; Mature: 375

Protein sequence:

>375_residues
MNYNSTEKFRILWRWWKSIDQYTVFLLCILSALSLMLVTTSGAAVANRIGVPQSYFASKHIFYVVLAVGTTFVVSFLNKT
TIKRLAILGFILNIILLIFIKFYGNPIKGAKRWINIGGISLQPSEFVKPFFLVITGWLLSAIQSNEIRFIVTIILYLIVA
LLLITQPDFGMLITISVAFGIQLFIAGIPLLWLLILICISIAGTAGAYSLLPHVKRRINSFLDPTNSENYQVMKSLQAFK
NGGLYGKGPGEGLVKHMLPDSHTDFIFAVAGEELGAIVCLIIVAIFTFIVIYGFIKLLFEEDNYTIFVSSGILSQFGFQA
IVNMCVSTNLLPTKGMTLPFISYGGSSSVAVAIGVGILLALTRHKTDLSKYKLKI

Sequences:

>Translated_375_residues
MNYNSTEKFRILWRWWKSIDQYTVFLLCILSALSLMLVTTSGAAVANRIGVPQSYFASKHIFYVVLAVGTTFVVSFLNKT
TIKRLAILGFILNIILLIFIKFYGNPIKGAKRWINIGGISLQPSEFVKPFFLVITGWLLSAIQSNEIRFIVTIILYLIVA
LLLITQPDFGMLITISVAFGIQLFIAGIPLLWLLILICISIAGTAGAYSLLPHVKRRINSFLDPTNSENYQVMKSLQAFK
NGGLYGKGPGEGLVKHMLPDSHTDFIFAVAGEELGAIVCLIIVAIFTFIVIYGFIKLLFEEDNYTIFVSSGILSQFGFQA
IVNMCVSTNLLPTKGMTLPFISYGGSSSVAVAIGVGILLALTRHKTDLSKYKLKI
>Mature_375_residues
MNYNSTEKFRILWRWWKSIDQYTVFLLCILSALSLMLVTTSGAAVANRIGVPQSYFASKHIFYVVLAVGTTFVVSFLNKT
TIKRLAILGFILNIILLIFIKFYGNPIKGAKRWINIGGISLQPSEFVKPFFLVITGWLLSAIQSNEIRFIVTIILYLIVA
LLLITQPDFGMLITISVAFGIQLFIAGIPLLWLLILICISIAGTAGAYSLLPHVKRRINSFLDPTNSENYQVMKSLQAFK
NGGLYGKGPGEGLVKHMLPDSHTDFIFAVAGEELGAIVCLIIVAIFTFIVIYGFIKLLFEEDNYTIFVSSGILSQFGFQA
IVNMCVSTNLLPTKGMTLPFISYGGSSSVAVAIGVGILLALTRHKTDLSKYKLKI

Specific function: This is a septum-peptidoglycan biosynthetic protein, involved in cell wall formation. Plays a role in the stabilization of the ftsZ ring during cell division [H]

COG id: COG0772

COG function: function code D; Bacterial cell division membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsW/rodA/spoVE family [H]

Homologues:

Organism=Escherichia coli, GI1786277, Length=366, Percent_Identity=31.6939890710383, Blast_Score=159, Evalue=3e-40,
Organism=Escherichia coli, GI1786853, Length=292, Percent_Identity=29.1095890410959, Blast_Score=109, Evalue=3e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001182
- InterPro:   IPR018365
- InterPro:   IPR013437 [H]

Pfam domain/function: PF01098 FTSW_RODA_SPOVE [H]

EC number: NA

Molecular weight: Translated: 41449; Mature: 41449

Theoretical pI: Translated: 9.97; Mature: 9.97

Prosite motif: PS00012 PHOSPHOPANTETHEINE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNYNSTEKFRILWRWWKSIDQYTVFLLCILSALSLMLVTTSGAAVANRIGVPQSYFASKH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
IFYVVLAVGTTFVVSFLNKTTIKRLAILGFILNIILLIFIKFYGNPIKGAKRWINIGGIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCC
LQPSEFVKPFFLVITGWLLSAIQSNEIRFIVTIILYLIVALLLITQPDFGMLITISVAFG
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHH
IQLFIAGIPLLWLLILICISIAGTAGAYSLLPHVKRRINSFLDPTNSENYQVMKSLQAFK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
NGGLYGKGPGEGLVKHMLPDSHTDFIFAVAGEELGAIVCLIIVAIFTFIVIYGFIKLLFE
CCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDNYTIFVSSGILSQFGFQAIVNMCVSTNLLPTKGMTLPFISYGGSSSVAVAIGVGILLA
CCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHH
LTRHKTDLSKYKLKI
HHHCCCCHHHHEECC
>Mature Secondary Structure
MNYNSTEKFRILWRWWKSIDQYTVFLLCILSALSLMLVTTSGAAVANRIGVPQSYFASKH
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHCCCCHHHHHHHH
IFYVVLAVGTTFVVSFLNKTTIKRLAILGFILNIILLIFIKFYGNPIKGAKRWINIGGIS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHEEECCCCC
LQPSEFVKPFFLVITGWLLSAIQSNEIRFIVTIILYLIVALLLITQPDFGMLITISVAFG
CCHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEHHHHHH
IQLFIAGIPLLWLLILICISIAGTAGAYSLLPHVKRRINSFLDPTNSENYQVMKSLQAFK
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
NGGLYGKGPGEGLVKHMLPDSHTDFIFAVAGEELGAIVCLIIVAIFTFIVIYGFIKLLFE
CCCCCCCCCCHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDNYTIFVSSGILSQFGFQAIVNMCVSTNLLPTKGMTLPFISYGGSSSVAVAIGVGILLA
CCCEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHH
LTRHKTDLSKYKLKI
HHHCCCCHHHHEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]