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The map label for this gene is dnaZX [H]

Identifier: 189026228

GI number: 189026228

Start: 1094677

End: 1096395

Strand: Reverse

Name: dnaZX [H]

Synonym: TPASS_1005

Alternate gene names: 189026228

Gene position: 1096395-1094677 (Counterclockwise)

Preceding gene: 189026229

Following gene: 189026227

Centisome position: 96.22

GC content: 50.44

Gene sequence:

>1719_bases
GTGGCGTATCAAGTGACGGCAACACGGTATCGGCCGCAACGTTTTCAGCACGTGTTGGGTCAGAAGTTTGTAGTGGCAAC
ACTGCAAAAATCTCTTGAGGAGAACAAAGTTTCTCCTGCGTATTTGTTTTCCGGCCCACATGGGTGTGGTAAGACCAGCT
GTGCGCGTATCCTTGCAAAGGCATTGAATTGTGTGCAAAGAGAAGCGTCTGAACCGTGTGGAGAGTGTCCGTCTTGTAGA
GAGATTGCCACCGGTACTAATTTAAATGTTATCGAAATTGACGGTGCGTCACACACAGGGGTGGGCGACGTACGTCAGAT
TAAGGAAGAGATTCTCTTTCCACCTCATGGGACGCGTTACAAGGTTTTTATTATTGATGAGGTGCATATGCTTTCAAACA
GTGCCTTTAATGCACTGTTGAAGACAATCGAAGAGCCTCCGCCGTATGTGGTATTTATCTTTGCAACAACGGAGGTGCAC
AGGATTCCTGCAACGGTAAAAAGTCGCTGTCAACAATTTCATTTTCGTTTGGTAGATACTCAGACGCTTGTTTGTGCGTT
GGCGCAAGCTGCCCAGCAGATGCAGATTGCAGTTGAAGACGGAGTACTGTCTTGGATTGCGCGTGAGTCAGCCGGTAGCA
TGCGAGACGCATATACTTTGTTCGATCAAACCGTGGTGTCTTGCGCAGGGCCGGTAACACTTGAGAACATTCAAAAAAAA
CTCGGGCTAATGACTGACGACTCACTTGCAGCACTGTTTTCACATTGCTGCCGCAAAGATGCTCGCGCCGCCTTGGAATT
GGTAGATGCTTTGGTAAGTTCTGGTGTCTCCGTTGAACAGTGCGTAATCGACTGTGTCCGCTATGCGCGTGCACTGTTGC
TTTTCACGCAGGGAATTACAAATGAGTCACTGGTAGGAATAGCGGCAAACCAAGTGCCTGAGTACGTGCGTACCACATGG
AATGCGTCGCAGATTGAGCGGGCGCTTGGACTGTTACTGCAACTGTTTCGCGACATTCGTTTTTCAGTAGATCCGCGGTA
TGAATTGGAGCTCGCAATTTCGCGTTTAGCGTGGTTGAGTGAGTATGTCTCAATTCAAGAAGTACGCGTTGCATTGGATA
GTGTGCAGCAGATACTGGACACGCATGCAGTTCCCGGGGTGTGTTCTGCGTCTGTAGGTTCGGACGATGGGGAAACAGGT
GTCGTCTCCCCACACGGTATACGTCCCCCTATGTCAACATCAGTATGTACCGTGCGTGCGTTACAAGATGCCTTGGTAGA
AAAGTTGCGCGCGTCACACCAGATGTTGGCAACAGCGCTTGGTTCTTCATATTCTTGGCGCGAGGAAGATACTTCTGTGT
GCATGTGCGTACGCACGCATTATGAGCGCAGCGTTATCTCTCAGCACGCGTCGCTGCTCAAGGAGTATGCGTCAGAATTA
CTGGGACGGGAGGTATGCGTTCGCGTACTTCTGGATTCGGTGCCTTCGTCAAAAGTCGCGCCCTCCCATCTTCCTCAGAG
TCCTGCCCCATCTGCTCTCTTTACAACTTCTTTGCTTATCTCTGGGCAGGAGTGTGATAGGGTGAGTGGAGATCTGCCTG
CACAGGTGAAGCTTCTCTGTGATTGTGTGCAAGGGCACGTGGTGCGTGTGTATGAAGGTACTGCACGGTGTGTACCTGGG
GAGGGGAAAATAGCAGGGGCTGTGCGTACTCCGTATTGA

Upstream 100 bases:

>100_bases
TTTATTGAAGAGAATGCAATATATGCGCGTTTGGACGTATGAATGTTTTGTGCATTTGTATTTCCATGTGAGTGGTGCCG
TCTGACAGGGGGAAGGATCA

Downstream 100 bases:

>100_bases
GTAGCGACAGACGGGTAGGAAGAGTGCGAAAGCTGTCAGTTCAATATGGGGATTTTGTACCAGGGGATGTGTGATGATAC
CGGCGATTGAAGAAGTAGTG

Product: DNA polymerase III subunits gamma and tau

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 572; Mature: 571

Protein sequence:

>572_residues
MAYQVTATRYRPQRFQHVLGQKFVVATLQKSLEENKVSPAYLFSGPHGCGKTSCARILAKALNCVQREASEPCGECPSCR
EIATGTNLNVIEIDGASHTGVGDVRQIKEEILFPPHGTRYKVFIIDEVHMLSNSAFNALLKTIEEPPPYVVFIFATTEVH
RIPATVKSRCQQFHFRLVDTQTLVCALAQAAQQMQIAVEDGVLSWIARESAGSMRDAYTLFDQTVVSCAGPVTLENIQKK
LGLMTDDSLAALFSHCCRKDARAALELVDALVSSGVSVEQCVIDCVRYARALLLFTQGITNESLVGIAANQVPEYVRTTW
NASQIERALGLLLQLFRDIRFSVDPRYELELAISRLAWLSEYVSIQEVRVALDSVQQILDTHAVPGVCSASVGSDDGETG
VVSPHGIRPPMSTSVCTVRALQDALVEKLRASHQMLATALGSSYSWREEDTSVCMCVRTHYERSVISQHASLLKEYASEL
LGREVCVRVLLDSVPSSKVAPSHLPQSPAPSALFTTSLLISGQECDRVSGDLPAQVKLLCDCVQGHVVRVYEGTARCVPG
EGKIAGAVRTPY

Sequences:

>Translated_572_residues
MAYQVTATRYRPQRFQHVLGQKFVVATLQKSLEENKVSPAYLFSGPHGCGKTSCARILAKALNCVQREASEPCGECPSCR
EIATGTNLNVIEIDGASHTGVGDVRQIKEEILFPPHGTRYKVFIIDEVHMLSNSAFNALLKTIEEPPPYVVFIFATTEVH
RIPATVKSRCQQFHFRLVDTQTLVCALAQAAQQMQIAVEDGVLSWIARESAGSMRDAYTLFDQTVVSCAGPVTLENIQKK
LGLMTDDSLAALFSHCCRKDARAALELVDALVSSGVSVEQCVIDCVRYARALLLFTQGITNESLVGIAANQVPEYVRTTW
NASQIERALGLLLQLFRDIRFSVDPRYELELAISRLAWLSEYVSIQEVRVALDSVQQILDTHAVPGVCSASVGSDDGETG
VVSPHGIRPPMSTSVCTVRALQDALVEKLRASHQMLATALGSSYSWREEDTSVCMCVRTHYERSVISQHASLLKEYASEL
LGREVCVRVLLDSVPSSKVAPSHLPQSPAPSALFTTSLLISGQECDRVSGDLPAQVKLLCDCVQGHVVRVYEGTARCVPG
EGKIAGAVRTPY
>Mature_571_residues
AYQVTATRYRPQRFQHVLGQKFVVATLQKSLEENKVSPAYLFSGPHGCGKTSCARILAKALNCVQREASEPCGECPSCRE
IATGTNLNVIEIDGASHTGVGDVRQIKEEILFPPHGTRYKVFIIDEVHMLSNSAFNALLKTIEEPPPYVVFIFATTEVHR
IPATVKSRCQQFHFRLVDTQTLVCALAQAAQQMQIAVEDGVLSWIARESAGSMRDAYTLFDQTVVSCAGPVTLENIQKKL
GLMTDDSLAALFSHCCRKDARAALELVDALVSSGVSVEQCVIDCVRYARALLLFTQGITNESLVGIAANQVPEYVRTTWN
ASQIERALGLLLQLFRDIRFSVDPRYELELAISRLAWLSEYVSIQEVRVALDSVQQILDTHAVPGVCSASVGSDDGETGV
VSPHGIRPPMSTSVCTVRALQDALVEKLRASHQMLATALGSSYSWREEDTSVCMCVRTHYERSVISQHASLLKEYASELL
GREVCVRVLLDSVPSSKVAPSHLPQSPAPSALFTTSLLISGQECDRVSGDLPAQVKLLCDCVQGHVVRVYEGTARCVPGE
GKIAGAVRTPY

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI4506491, Length=284, Percent_Identity=27.112676056338, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI31881687, Length=284, Percent_Identity=27.112676056338, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI6677723, Length=280, Percent_Identity=22.1428571428571, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI194306571, Length=280, Percent_Identity=22.1428571428571, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI194306567, Length=280, Percent_Identity=22.1428571428571, Blast_Score=70, Evalue=8e-12,
Organism=Escherichia coli, GI1786676, Length=286, Percent_Identity=40.5594405594406, Blast_Score=237, Evalue=2e-63,
Organism=Caenorhabditis elegans, GI17541988, Length=290, Percent_Identity=23.7931034482759, Blast_Score=75, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322528, Length=340, Percent_Identity=24.7058823529412, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI17647857, Length=284, Percent_Identity=25.7042253521127, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI18859927, Length=228, Percent_Identity=28.0701754385965, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI19921076, Length=295, Percent_Identity=24.7457627118644, Blast_Score=67, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 62486; Mature: 62355

Theoretical pI: Translated: 6.55; Mature: 6.55

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.8 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.9 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYQVTATRYRPQRFQHVLGQKFVVATLQKSLEENKVSPAYLFSGPHGCGKTSCARILAK
CCEEEEHHHCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
ALNCVQREASEPCGECPSCREIATGTNLNVIEIDGASHTGVGDVRQIKEEILFPPHGTRY
HHHHHHHHHCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEE
KVFIIDEVHMLSNSAFNALLKTIEEPPPYVVFIFATTEVHRIPATVKSRCQQFHFRLVDT
EEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHCCHHHHHHHHHHHHHHHHH
QTLVCALAQAAQQMQIAVEDGVLSWIARESAGSMRDAYTLFDQTVVSCAGPVTLENIQKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
LGLMTDDSLAALFSHCCRKDARAALELVDALVSSGVSVEQCVIDCVRYARALLLFTQGIT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
NESLVGIAANQVPEYVRTTWNASQIERALGLLLQLFRDIRFSVDPRYELELAISRLAWLS
CCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
EYVSIQEVRVALDSVQQILDTHAVPGVCSASVGSDDGETGVVSPHGIRPPMSTSVCTVRA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LQDALVEKLRASHQMLATALGSSYSWREEDTSVCMCVRTHYERSVISQHASLLKEYASEL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGREVCVRVLLDSVPSSKVAPSHLPQSPAPSALFTTSLLISGQECDRVSGDLPAQVKLLC
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCHHHHHHH
DCVQGHVVRVYEGTARCVPGEGKIAGAVRTPY
HHHCCCEEEEEECCCEECCCCCCEECCCCCCC
>Mature Secondary Structure 
AYQVTATRYRPQRFQHVLGQKFVVATLQKSLEENKVSPAYLFSGPHGCGKTSCARILAK
CEEEEHHHCCHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEECCCCCCCHHHHHHHHHH
ALNCVQREASEPCGECPSCREIATGTNLNVIEIDGASHTGVGDVRQIKEEILFPPHGTRY
HHHHHHHHHCCCCCCCCCCHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHHCCCCCCCEE
KVFIIDEVHMLSNSAFNALLKTIEEPPPYVVFIFATTEVHRIPATVKSRCQQFHFRLVDT
EEEEEECHHHHHHHHHHHHHHHHCCCCCEEEEEEEECHHHHCCHHHHHHHHHHHHHHHHH
QTLVCALAQAAQQMQIAVEDGVLSWIARESAGSMRDAYTLFDQTVVSCAGPVTLENIQKK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHH
LGLMTDDSLAALFSHCCRKDARAALELVDALVSSGVSVEQCVIDCVRYARALLLFTQGIT
HCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCC
NESLVGIAANQVPEYVRTTWNASQIERALGLLLQLFRDIRFSVDPRYELELAISRLAWLS
CCCEEEHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHH
EYVSIQEVRVALDSVQQILDTHAVPGVCSASVGSDDGETGVVSPHGIRPPMSTSVCTVRA
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LQDALVEKLRASHQMLATALGSSYSWREEDTSVCMCVRTHYERSVISQHASLLKEYASEL
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LGREVCVRVLLDSVPSSKVAPSHLPQSPAPSALFTTSLLISGQECDRVSGDLPAQVKLLC
HHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHCCCCHHHHCCCCCCHHHHHHH
DCVQGHVVRVYEGTARCVPGEGKIAGAVRTPY
HHHCCCEEEEEECCCEECCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]