The gene/protein map for NC_010741 is currently unavailable.
Definition Treponema pallidum subsp. pallidum SS14, complete genome.
Accession NC_010741
Length 1,139,457

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The map label for this gene is ftsH

Identifier: 189025990

GI number: 189025990

Start: 829820

End: 831649

Strand: Reverse

Name: ftsH

Synonym: TPASS_0765

Alternate gene names: 189025990

Gene position: 831649-829820 (Counterclockwise)

Preceding gene: 189025996

Following gene: 189025988

Centisome position: 72.99

GC content: 52.95

Gene sequence:

>1830_bases
TTGCGCATCATCCCGTTCTCGGAATTTAAAGATCGCATTGCAAGTGGGGAAATCGTAAAGGTTGTTGTCGGTTCCCCTTA
CTTTGTCGGGTACACTTCCGCGCGCCCTGCGCCTTCTGCGCGGGGTTTCTCGTTGCTCTCTGAGCGGGAGGCTCCTACCT
ATCATGCCATCGGTGTCCTCTCCGATTCCTTTTTGAGCATGCTCGATGAGCGGCAGGTGGTCTACAGTATTAAGCCGCGC
GAGCGCAATTACCTCATAGAGACATTTCAATATCTCTTTCCGCTGCTCATCCTCTTTTTTGTCTGGCGCTTTTTCTTTAA
GCGGATGGCCTCAAATGTAAGCGGGCTGGGGAGCAGTATTTTCTCAGCCGGACACGCGCGCTCTGCGGCGGTGGAAGAAG
GAAAGGTCACCACACGCTTTGCAGACGTTGCAGGGGTGGATGAGGCAAAAGAAGAGCTGATGGAAGTAGTTGATTTTCTC
AAGTTCCCTAAAAAGTATACTGAAATCGGGGGGAAAATTCCCCGCGGGGTGCTGTTGGTCGGTCCCCCAGGGACGGGTAA
GACGTTGCTTGCACGCGCAGTGGCAGGTGAGGCGTCAGTGCCCTTTTTTCGCATCAGTGGCTCAGACTTCATCGAAATGT
TTGTGGGGATTGGCGCCTCGCGTGTGCGCGATTTATTCAAACAAGCGCGGGAGAAGGCGCCAGGGATTATTTTTATCGAT
GAGCTTGACGCAATTGGAAAAAGCCGCCTGAACGCTATCCATTCCAACGATGAGCGGGAACAAACGCTTAACCAGCTTCT
GGTAGAAATGGATGGGTTTGATAACACCACCGGTCTCATTTTGCTTGCTGCTACCAATCGCCCCGATGTGTTAGATCCTG
CGCTCCTACGCCCCGGTCGTTTTGACCGACAGGTTTGCGTAGATCGGCCCGATCTTAAGGGAAGAGAGGCAATTCTGCGT
ATTCATGCGCAGAACGTGAAGTTAGCGCCAGAAGTGGATTTGAAGGCAGTGGCGCGCATCACCGGTGGGTATTCAGGTGC
TGATTTGGCAAACGTGGTGAACGAGGCAGCGTTGCTCGCGGTACGGTCTGGGCGTGCGCAGGTGATTGAAACGGATTTGG
ACGAAGCGGTCGAAAAGACAATGATAGGATTGCAGAAAAAAAGTCGGGTAATTCGAGAAGAAGAGCGCCGGATTATTGCG
TATCACGAGACAGGACATGCCCTTGCAGGTACCTTCACGAAGGGTGCAGACAAGGTGCACAAAATTACAATTATTCCCCG
GGGCACCTCTGCGCTTGGATATACTTTTCACATTCCTGAAGACGATCGGCATATTGTTACGGAGCAGCAGTTGTTGGCAG
AAGTAGATGTGCTGCTTTCAGGACGCGCAGCGGAATTTGTAGCCTTTGGGGAAGTTTCAACTGGTGCAGGGAACGATATT
TCTCGCGCAACAGACATTGTCCGCAAGATGATTACAGATTATGGGATGAGCGAAAAGTTTCAAAACGTTGCACTTACTCG
CCGCGGAACCGGGTATCTCGCGGAGCCGCAGTTAGCGCGCGAGTATTCGGAGTGCACACAGCAGTACGTTGATGAGGAAG
TGGCGCGCGTTCTAGCTGAGCGCTACCGCGCGGTGGTAGCACTCTTGACGGAGAAAAAAGAGCTCCTTGAGTACATCGCA
ACGCGCCTTTTGGAGCGAGAAACCATCGAGCGCGACGAGTTTGAGGAAGTTATTCGCTGCGAACACGACCTAGAGGGGCT
AAAAAAGCGTCTAAGCCAGCAGCAGGAAGGGGCATCTGCCCCTGCGCAGGGTCAGTCGCCACCTTCCTGA

Upstream 100 bases:

>100_bases
AAGACCTCCGCGCAGAAATTCGCGTAAGGTGCTCTCGCTCGTGCTCCTTGCTCTTTGTGCGCTGCTTGCTCTTGCAAACC
ACTTTTTGTTTTCCCGTGCT

Downstream 100 bases:

>100_bases
AGGATAAGACGCTGTTCCTTTACGCTCAGGGCCCGCGTGATAAAAATTTCGTCTGCGCTCGTGCTGTGAATGATGGGCTT
GCCGTTGCGGTGAATTTCTC

Product: cell division protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 609; Mature: 609

Protein sequence:

>609_residues
MRIIPFSEFKDRIASGEIVKVVVGSPYFVGYTSARPAPSARGFSLLSEREAPTYHAIGVLSDSFLSMLDERQVVYSIKPR
ERNYLIETFQYLFPLLILFFVWRFFFKRMASNVSGLGSSIFSAGHARSAAVEEGKVTTRFADVAGVDEAKEELMEVVDFL
KFPKKYTEIGGKIPRGVLLVGPPGTGKTLLARAVAGEASVPFFRISGSDFIEMFVGIGASRVRDLFKQAREKAPGIIFID
ELDAIGKSRLNAIHSNDEREQTLNQLLVEMDGFDNTTGLILLAATNRPDVLDPALLRPGRFDRQVCVDRPDLKGREAILR
IHAQNVKLAPEVDLKAVARITGGYSGADLANVVNEAALLAVRSGRAQVIETDLDEAVEKTMIGLQKKSRVIREEERRIIA
YHETGHALAGTFTKGADKVHKITIIPRGTSALGYTFHIPEDDRHIVTEQQLLAEVDVLLSGRAAEFVAFGEVSTGAGNDI
SRATDIVRKMITDYGMSEKFQNVALTRRGTGYLAEPQLAREYSECTQQYVDEEVARVLAERYRAVVALLTEKKELLEYIA
TRLLERETIERDEFEEVIRCEHDLEGLKKRLSQQQEGASAPAQGQSPPS

Sequences:

>Translated_609_residues
MRIIPFSEFKDRIASGEIVKVVVGSPYFVGYTSARPAPSARGFSLLSEREAPTYHAIGVLSDSFLSMLDERQVVYSIKPR
ERNYLIETFQYLFPLLILFFVWRFFFKRMASNVSGLGSSIFSAGHARSAAVEEGKVTTRFADVAGVDEAKEELMEVVDFL
KFPKKYTEIGGKIPRGVLLVGPPGTGKTLLARAVAGEASVPFFRISGSDFIEMFVGIGASRVRDLFKQAREKAPGIIFID
ELDAIGKSRLNAIHSNDEREQTLNQLLVEMDGFDNTTGLILLAATNRPDVLDPALLRPGRFDRQVCVDRPDLKGREAILR
IHAQNVKLAPEVDLKAVARITGGYSGADLANVVNEAALLAVRSGRAQVIETDLDEAVEKTMIGLQKKSRVIREEERRIIA
YHETGHALAGTFTKGADKVHKITIIPRGTSALGYTFHIPEDDRHIVTEQQLLAEVDVLLSGRAAEFVAFGEVSTGAGNDI
SRATDIVRKMITDYGMSEKFQNVALTRRGTGYLAEPQLAREYSECTQQYVDEEVARVLAERYRAVVALLTEKKELLEYIA
TRLLERETIERDEFEEVIRCEHDLEGLKKRLSQQQEGASAPAQGQSPPS
>Mature_609_residues
MRIIPFSEFKDRIASGEIVKVVVGSPYFVGYTSARPAPSARGFSLLSEREAPTYHAIGVLSDSFLSMLDERQVVYSIKPR
ERNYLIETFQYLFPLLILFFVWRFFFKRMASNVSGLGSSIFSAGHARSAAVEEGKVTTRFADVAGVDEAKEELMEVVDFL
KFPKKYTEIGGKIPRGVLLVGPPGTGKTLLARAVAGEASVPFFRISGSDFIEMFVGIGASRVRDLFKQAREKAPGIIFID
ELDAIGKSRLNAIHSNDEREQTLNQLLVEMDGFDNTTGLILLAATNRPDVLDPALLRPGRFDRQVCVDRPDLKGREAILR
IHAQNVKLAPEVDLKAVARITGGYSGADLANVVNEAALLAVRSGRAQVIETDLDEAVEKTMIGLQKKSRVIREEERRIIA
YHETGHALAGTFTKGADKVHKITIIPRGTSALGYTFHIPEDDRHIVTEQQLLAEVDVLLSGRAAEFVAFGEVSTGAGNDI
SRATDIVRKMITDYGMSEKFQNVALTRRGTGYLAEPQLAREYSECTQQYVDEEVARVLAERYRAVVALLTEKKELLEYIA
TRLLERETIERDEFEEVIRCEHDLEGLKKRLSQQQEGASAPAQGQSPPS

Specific function: Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins

COG id: COG0465

COG function: function code O; ATP-dependent Zn proteases

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein; Cytoplasmic side

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the peptidase M41 family

Homologues:

Organism=Homo sapiens, GI300192933, Length=501, Percent_Identity=44.7105788423154, Blast_Score=434, Evalue=1e-122,
Organism=Homo sapiens, GI21327685, Length=442, Percent_Identity=47.9638009049774, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI7657689, Length=442, Percent_Identity=47.9638009049774, Blast_Score=385, Evalue=1e-107,
Organism=Homo sapiens, GI4507173, Length=492, Percent_Identity=41.260162601626, Blast_Score=379, Evalue=1e-105,
Organism=Homo sapiens, GI21361144, Length=255, Percent_Identity=40.7843137254902, Blast_Score=206, Evalue=6e-53,
Organism=Homo sapiens, GI24497435, Length=253, Percent_Identity=43.0830039525692, Blast_Score=206, Evalue=7e-53,
Organism=Homo sapiens, GI195539395, Length=243, Percent_Identity=42.798353909465, Blast_Score=205, Evalue=9e-53,
Organism=Homo sapiens, GI4506209, Length=262, Percent_Identity=41.9847328244275, Blast_Score=204, Evalue=1e-52,
Organism=Homo sapiens, GI24430151, Length=250, Percent_Identity=42.8, Blast_Score=200, Evalue=3e-51,
Organism=Homo sapiens, GI89064750, Length=252, Percent_Identity=42.4603174603175, Blast_Score=196, Evalue=8e-50,
Organism=Homo sapiens, GI5729991, Length=250, Percent_Identity=42.8, Blast_Score=195, Evalue=1e-49,
Organism=Homo sapiens, GI24430155, Length=250, Percent_Identity=42.8, Blast_Score=194, Evalue=1e-49,
Organism=Homo sapiens, GI6005942, Length=224, Percent_Identity=48.2142857142857, Blast_Score=194, Evalue=2e-49,
Organism=Homo sapiens, GI45643123, Length=228, Percent_Identity=41.6666666666667, Blast_Score=179, Evalue=5e-45,
Organism=Homo sapiens, GI45643125, Length=228, Percent_Identity=41.6666666666667, Blast_Score=179, Evalue=7e-45,
Organism=Homo sapiens, GI157671927, Length=223, Percent_Identity=40.8071748878924, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI40806173, Length=184, Percent_Identity=49.4565217391304, Blast_Score=170, Evalue=3e-42,
Organism=Homo sapiens, GI229577436, Length=243, Percent_Identity=38.2716049382716, Blast_Score=169, Evalue=5e-42,
Organism=Homo sapiens, GI24497618, Length=245, Percent_Identity=40, Blast_Score=166, Evalue=5e-41,
Organism=Homo sapiens, GI153792536, Length=290, Percent_Identity=36.8965517241379, Blast_Score=165, Evalue=9e-41,
Organism=Homo sapiens, GI4505725, Length=228, Percent_Identity=38.5964912280702, Blast_Score=163, Evalue=3e-40,
Organism=Homo sapiens, GI5901990, Length=233, Percent_Identity=39.9141630901288, Blast_Score=153, Evalue=4e-37,
Organism=Homo sapiens, GI194018488, Length=265, Percent_Identity=37.7358490566038, Blast_Score=152, Evalue=1e-36,
Organism=Homo sapiens, GI17865802, Length=234, Percent_Identity=40.5982905982906, Blast_Score=151, Evalue=2e-36,
Organism=Homo sapiens, GI7019569, Length=238, Percent_Identity=40.3361344537815, Blast_Score=147, Evalue=4e-35,
Organism=Homo sapiens, GI14149767, Length=233, Percent_Identity=37.7682403433476, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI62177112, Length=233, Percent_Identity=37.7682403433476, Blast_Score=146, Evalue=7e-35,
Organism=Homo sapiens, GI226371754, Length=235, Percent_Identity=38.2978723404255, Blast_Score=139, Evalue=7e-33,
Organism=Homo sapiens, GI11875211, Length=230, Percent_Identity=40.8695652173913, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI40806170, Length=230, Percent_Identity=40.8695652173913, Blast_Score=138, Evalue=2e-32,
Organism=Homo sapiens, GI31377644, Length=243, Percent_Identity=36.2139917695473, Blast_Score=136, Evalue=7e-32,
Organism=Homo sapiens, GI156564401, Length=235, Percent_Identity=36.5957446808511, Blast_Score=129, Evalue=8e-30,
Organism=Homo sapiens, GI31742536, Length=237, Percent_Identity=32.9113924050633, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI112789543, Length=237, Percent_Identity=32.9113924050633, Blast_Score=127, Evalue=3e-29,
Organism=Homo sapiens, GI310125282, Length=235, Percent_Identity=36.1702127659575, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI310125280, Length=232, Percent_Identity=36.2068965517241, Blast_Score=125, Evalue=1e-28,
Organism=Homo sapiens, GI64084766, Length=222, Percent_Identity=28.3783783783784, Blast_Score=98, Evalue=2e-20,
Organism=Homo sapiens, GI75677353, Length=236, Percent_Identity=30.9322033898305, Blast_Score=87, Evalue=4e-17,
Organism=Homo sapiens, GI116292174, Length=245, Percent_Identity=30.6122448979592, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI283436220, Length=246, Percent_Identity=28.0487804878049, Blast_Score=76, Evalue=1e-13,
Organism=Homo sapiens, GI283436222, Length=246, Percent_Identity=28.0487804878049, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI283436224, Length=246, Percent_Identity=28.0487804878049, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI4757852, Length=153, Percent_Identity=33.9869281045752, Blast_Score=70, Evalue=8e-12,
Organism=Homo sapiens, GI119964730, Length=153, Percent_Identity=33.9869281045752, Blast_Score=70, Evalue=8e-12,
Organism=Escherichia coli, GI1789568, Length=518, Percent_Identity=48.0694980694981, Blast_Score=482, Evalue=1e-137,
Organism=Caenorhabditis elegans, GI71994521, Length=448, Percent_Identity=45.3125, Blast_Score=403, Evalue=1e-112,
Organism=Caenorhabditis elegans, GI17554264, Length=460, Percent_Identity=47.1739130434783, Blast_Score=381, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI115534323, Length=457, Percent_Identity=41.3566739606127, Blast_Score=353, Evalue=1e-97,
Organism=Caenorhabditis elegans, GI17554786, Length=253, Percent_Identity=43.8735177865613, Blast_Score=210, Evalue=2e-54,
Organism=Caenorhabditis elegans, GI17563248, Length=262, Percent_Identity=42.7480916030534, Blast_Score=206, Evalue=4e-53,
Organism=Caenorhabditis elegans, GI25144278, Length=253, Percent_Identity=43.4782608695652, Blast_Score=205, Evalue=5e-53,
Organism=Caenorhabditis elegans, GI25144281, Length=253, Percent_Identity=43.4782608695652, Blast_Score=205, Evalue=6e-53,
Organism=Caenorhabditis elegans, GI71987364, Length=242, Percent_Identity=43.801652892562, Blast_Score=205, Evalue=7e-53,
Organism=Caenorhabditis elegans, GI71987372, Length=242, Percent_Identity=43.801652892562, Blast_Score=204, Evalue=8e-53,
Organism=Caenorhabditis elegans, GI17508701, Length=255, Percent_Identity=39.6078431372549, Blast_Score=197, Evalue=9e-51,
Organism=Caenorhabditis elegans, GI17563250, Length=245, Percent_Identity=43.6734693877551, Blast_Score=196, Evalue=3e-50,
Organism=Caenorhabditis elegans, GI17505546, Length=245, Percent_Identity=41.6326530612245, Blast_Score=190, Evalue=2e-48,
Organism=Caenorhabditis elegans, GI17532375, Length=247, Percent_Identity=38.8663967611336, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17531535, Length=282, Percent_Identity=37.2340425531915, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17554784, Length=244, Percent_Identity=41.3934426229508, Blast_Score=182, Evalue=4e-46,
Organism=Caenorhabditis elegans, GI17508053, Length=225, Percent_Identity=42.6666666666667, Blast_Score=173, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI17537217, Length=204, Percent_Identity=42.156862745098, Blast_Score=160, Evalue=2e-39,
Organism=Caenorhabditis elegans, GI133931034, Length=236, Percent_Identity=41.1016949152542, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI193206114, Length=236, Percent_Identity=41.1016949152542, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI193206116, Length=236, Percent_Identity=41.1016949152542, Blast_Score=157, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI25153574, Length=246, Percent_Identity=35.7723577235772, Blast_Score=150, Evalue=2e-36,
Organism=Caenorhabditis elegans, GI86561515, Length=240, Percent_Identity=38.3333333333333, Blast_Score=147, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI193209502, Length=223, Percent_Identity=35.8744394618834, Blast_Score=139, Evalue=4e-33,
Organism=Caenorhabditis elegans, GI17570397, Length=165, Percent_Identity=43.030303030303, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI32566590, Length=165, Percent_Identity=43.030303030303, Blast_Score=137, Evalue=2e-32,
Organism=Caenorhabditis elegans, GI133901658, Length=242, Percent_Identity=38.4297520661157, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI133901662, Length=242, Percent_Identity=38.4297520661157, Blast_Score=135, Evalue=6e-32,
Organism=Caenorhabditis elegans, GI17562804, Length=275, Percent_Identity=30.5454545454545, Blast_Score=134, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17560432, Length=261, Percent_Identity=37.5478927203065, Blast_Score=133, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI25146157, Length=242, Percent_Identity=36.7768595041322, Blast_Score=127, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32563584, Length=231, Percent_Identity=36.3636363636364, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17508421, Length=231, Percent_Identity=36.3636363636364, Blast_Score=112, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI17541226, Length=272, Percent_Identity=32.7205882352941, Blast_Score=112, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI17541224, Length=272, Percent_Identity=32.7205882352941, Blast_Score=112, Evalue=8e-25,
Organism=Caenorhabditis elegans, GI71990294, Length=199, Percent_Identity=30.1507537688442, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6323736, Length=542, Percent_Identity=46.309963099631, Blast_Score=449, Evalue=1e-127,
Organism=Saccharomyces cerevisiae, GI6320854, Length=604, Percent_Identity=40.7284768211921, Blast_Score=434, Evalue=1e-122,
Organism=Saccharomyces cerevisiae, GI6325281, Length=512, Percent_Identity=43.5546875, Blast_Score=399, Evalue=1e-112,
Organism=Saccharomyces cerevisiae, GI6322704, Length=262, Percent_Identity=41.2213740458015, Blast_Score=204, Evalue=2e-53,
Organism=Saccharomyces cerevisiae, GI6321390, Length=241, Percent_Identity=43.1535269709544, Blast_Score=204, Evalue=3e-53,
Organism=Saccharomyces cerevisiae, GI6324833, Length=253, Percent_Identity=43.8735177865613, Blast_Score=203, Evalue=8e-53,
Organism=Saccharomyces cerevisiae, GI6320197, Length=248, Percent_Identity=43.1451612903226, Blast_Score=202, Evalue=1e-52,
Organism=Saccharomyces cerevisiae, GI6320602, Length=250, Percent_Identity=45.2, Blast_Score=201, Evalue=2e-52,
Organism=Saccharomyces cerevisiae, GI6324691, Length=255, Percent_Identity=42.3529411764706, Blast_Score=201, Evalue=4e-52,
Organism=Saccharomyces cerevisiae, GI6320077, Length=247, Percent_Identity=42.1052631578947, Blast_Score=199, Evalue=2e-51,
Organism=Saccharomyces cerevisiae, GI6322994, Length=256, Percent_Identity=36.328125, Blast_Score=167, Evalue=3e-42,
Organism=Saccharomyces cerevisiae, GI6321709, Length=260, Percent_Identity=36.9230769230769, Blast_Score=166, Evalue=9e-42,
Organism=Saccharomyces cerevisiae, GI6323429, Length=224, Percent_Identity=38.3928571428571, Blast_Score=158, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6324000, Length=245, Percent_Identity=37.1428571428571, Blast_Score=158, Evalue=3e-39,
Organism=Saccharomyces cerevisiae, GI6325431, Length=244, Percent_Identity=40.9836065573771, Blast_Score=153, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6322651, Length=237, Percent_Identity=36.7088607594937, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6319554, Length=216, Percent_Identity=36.1111111111111, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6325183, Length=252, Percent_Identity=33.3333333333333, Blast_Score=124, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6320887, Length=257, Percent_Identity=34.2412451361868, Blast_Score=122, Evalue=2e-28,
Organism=Saccharomyces cerevisiae, GI6321465, Length=239, Percent_Identity=34.7280334728033, Blast_Score=117, Evalue=4e-27,
Organism=Saccharomyces cerevisiae, GI6320583, Length=157, Percent_Identity=31.8471337579618, Blast_Score=77, Evalue=8e-15,
Organism=Drosophila melanogaster, GI28574878, Length=442, Percent_Identity=46.8325791855204, Blast_Score=427, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24665814, Length=442, Percent_Identity=46.8325791855204, Blast_Score=426, Evalue=1e-119,
Organism=Drosophila melanogaster, GI24658770, Length=500, Percent_Identity=43.8, Blast_Score=399, Evalue=1e-111,
Organism=Drosophila melanogaster, GI24639391, Length=483, Percent_Identity=43.4782608695652, Blast_Score=385, Evalue=1e-107,
Organism=Drosophila melanogaster, GI24651451, Length=252, Percent_Identity=43.2539682539683, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI19920408, Length=253, Percent_Identity=43.0830039525692, Blast_Score=209, Evalue=4e-54,
Organism=Drosophila melanogaster, GI17137738, Length=262, Percent_Identity=42.3664122137405, Blast_Score=203, Evalue=2e-52,
Organism=Drosophila melanogaster, GI17738151, Length=255, Percent_Identity=41.1764705882353, Blast_Score=202, Evalue=7e-52,
Organism=Drosophila melanogaster, GI24640100, Length=248, Percent_Identity=43.1451612903226, Blast_Score=201, Evalue=1e-51,
Organism=Drosophila melanogaster, GI161076488, Length=239, Percent_Identity=41.8410041841004, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI161076486, Length=239, Percent_Identity=41.8410041841004, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI17137560, Length=239, Percent_Identity=41.8410041841004, Blast_Score=200, Evalue=3e-51,
Organism=Drosophila melanogaster, GI24649446, Length=245, Percent_Identity=42.8571428571429, Blast_Score=199, Evalue=6e-51,
Organism=Drosophila melanogaster, GI45554047, Length=198, Percent_Identity=53.030303030303, Blast_Score=198, Evalue=1e-50,
Organism=Drosophila melanogaster, GI24663015, Length=256, Percent_Identity=41.40625, Blast_Score=197, Evalue=3e-50,
Organism=Drosophila melanogaster, GI18860063, Length=249, Percent_Identity=41.3654618473896, Blast_Score=194, Evalue=2e-49,
Organism=Drosophila melanogaster, GI24660075, Length=282, Percent_Identity=38.6524822695035, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI281365776, Length=282, Percent_Identity=38.6524822695035, Blast_Score=192, Evalue=7e-49,
Organism=Drosophila melanogaster, GI45552965, Length=282, Percent_Identity=38.6524822695035, Blast_Score=191, Evalue=1e-48,
Organism=Drosophila melanogaster, GI281361487, Length=244, Percent_Identity=40.5737704918033, Blast_Score=189, Evalue=5e-48,
Organism=Drosophila melanogaster, GI24652279, Length=200, Percent_Identity=44.5, Blast_Score=179, Evalue=6e-45,
Organism=Drosophila melanogaster, GI19921202, Length=248, Percent_Identity=37.9032258064516, Blast_Score=178, Evalue=9e-45,
Organism=Drosophila melanogaster, GI281363136, Length=230, Percent_Identity=40.4347826086956, Blast_Score=166, Evalue=4e-41,
Organism=Drosophila melanogaster, GI78707192, Length=230, Percent_Identity=40.4347826086956, Blast_Score=166, Evalue=4e-41,
Organism=Drosophila melanogaster, GI18859657, Length=237, Percent_Identity=42.6160337552743, Blast_Score=162, Evalue=9e-40,
Organism=Drosophila melanogaster, GI24656820, Length=262, Percent_Identity=36.2595419847328, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI24656825, Length=262, Percent_Identity=36.2595419847328, Blast_Score=156, Evalue=4e-38,
Organism=Drosophila melanogaster, GI28571849, Length=237, Percent_Identity=43.4599156118143, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI28571847, Length=237, Percent_Identity=43.4599156118143, Blast_Score=149, Evalue=7e-36,
Organism=Drosophila melanogaster, GI24644145, Length=228, Percent_Identity=39.0350877192982, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281360144, Length=237, Percent_Identity=37.9746835443038, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281360140, Length=237, Percent_Identity=37.9746835443038, Blast_Score=145, Evalue=6e-35,
Organism=Drosophila melanogaster, GI281360136, Length=254, Percent_Identity=36.2204724409449, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI24644411, Length=254, Percent_Identity=36.2204724409449, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI281360146, Length=237, Percent_Identity=37.9746835443038, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI281360142, Length=237, Percent_Identity=37.9746835443038, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI281360138, Length=237, Percent_Identity=37.9746835443038, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21357333, Length=237, Percent_Identity=37.9746835443038, Blast_Score=145, Evalue=7e-35,
Organism=Drosophila melanogaster, GI21355121, Length=260, Percent_Identity=34.2307692307692, Blast_Score=141, Evalue=1e-33,
Organism=Drosophila melanogaster, GI24581396, Length=264, Percent_Identity=36.7424242424242, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI17864540, Length=210, Percent_Identity=37.6190476190476, Blast_Score=128, Evalue=1e-29,
Organism=Drosophila melanogaster, GI28573010, Length=210, Percent_Identity=36.6666666666667, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI20129529, Length=265, Percent_Identity=31.3207547169811, Blast_Score=122, Evalue=6e-28,
Organism=Drosophila melanogaster, GI20129423, Length=246, Percent_Identity=32.520325203252, Blast_Score=122, Evalue=8e-28,
Organism=Drosophila melanogaster, GI24639486, Length=285, Percent_Identity=29.4736842105263, Blast_Score=109, Evalue=5e-24,
Organism=Drosophila melanogaster, GI20129417, Length=154, Percent_Identity=33.7662337662338, Blast_Score=70, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24583262, Length=154, Percent_Identity=33.7662337662338, Blast_Score=70, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FTSH_TREPA (O83746)

Other databases:

- EMBL:   AE000520
- PIR:   H71285
- RefSeq:   NP_219202.1
- ProteinModelPortal:   O83746
- IntAct:   O83746
- GeneID:   2611374
- GenomeReviews:   AE000520_GR
- KEGG:   tpa:TP0765
- NMPDR:   fig|243276.1.peg.761
- TIGR:   TP_0765
- HOGENOM:   HBG724153
- OMA:   NRPNRRF
- ProtClustDB:   CLSK218643
- BioCyc:   TPAL243276:TP_0765-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01458
- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR003960
- InterPro:   IPR005936
- InterPro:   IPR000642
- SMART:   SM00382
- TIGRFAMs:   TIGR01241

Pfam domain/function: PF00004 AAA; PF01434 Peptidase_M41

EC number: 3.4.24.-

Molecular weight: Translated: 67545; Mature: 67545

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00674 AAA

Important sites: ACT_SITE 403-403

Signals:

None

Transmembrane regions:

HASH(0x21779c00)-;

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIIPFSEFKDRIASGEIVKVVVGSPYFVGYTSARPAPSARGFSLLSEREAPTYHAIGVL
CCCCCHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHH
SDSFLSMLDERQVVYSIKPRERNYLIETFQYLFPLLILFFVWRFFFKRMASNVSGLGSSI
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSAGHARSAAVEEGKVTTRFADVAGVDEAKEELMEVVDFLKFPKKYTEIGGKIPRGVLLV
HHCCCCHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEE
GPPGTGKTLLARAVAGEASVPFFRISGSDFIEMFVGIGASRVRDLFKQAREKAPGIIFID
CCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEE
ELDAIGKSRLNAIHSNDEREQTLNQLLVEMDGFDNTTGLILLAATNRPDVLDPALLRPGR
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCC
FDRQVCVDRPDLKGREAILRIHAQNVKLAPEVDLKAVARITGGYSGADLANVVNEAALLA
CCCHHHCCCCCCCCCHHHHEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHH
VRSGRAQVIETDLDEAVEKTMIGLQKKSRVIREEERRIIAYHETGHALAGTFTKGADKVH
HHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHCCCCCCCCCEE
KITIIPRGTSALGYTFHIPEDDRHIVTEQQLLAEVDVLLSGRAAEFVAFGEVSTGAGNDI
EEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCH
SRATDIVRKMITDYGMSEKFQNVALTRRGTGYLAEPQLAREYSECTQQYVDEEVARVLAE
HHHHHHHHHHHHHCCCHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RYRAVVALLTEKKELLEYIATRLLERETIERDEFEEVIRCEHDLEGLKKRLSQQQEGASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAQGQSPPS
CCCCCCCCH
>Mature Secondary Structure
MRIIPFSEFKDRIASGEIVKVVVGSPYFVGYTSARPAPSARGFSLLSEREAPTYHAIGVL
CCCCCHHHHHHHHCCCCEEEEEECCCEEEEECCCCCCCCCCCHHHHHHCCCCCCHHHHHH
SDSFLSMLDERQVVYSIKPRERNYLIETFQYLFPLLILFFVWRFFFKRMASNVSGLGSSI
HHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FSAGHARSAAVEEGKVTTRFADVAGVDEAKEELMEVVDFLKFPKKYTEIGGKIPRGVLLV
HHCCCCHHHHHCCCCCHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCEEEE
GPPGTGKTLLARAVAGEASVPFFRISGSDFIEMFVGIGASRVRDLFKQAREKAPGIIFID
CCCCCCHHHHHHHHCCCCCCCEEEECCHHHHHHHHHCCHHHHHHHHHHHHHCCCCEEEEE
ELDAIGKSRLNAIHSNDEREQTLNQLLVEMDGFDNTTGLILLAATNRPDVLDPALLRPGR
CHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCCCCHHHCCCCC
FDRQVCVDRPDLKGREAILRIHAQNVKLAPEVDLKAVARITGGYSGADLANVVNEAALLA
CCCHHHCCCCCCCCCHHHHEEECCCCCCCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHH
VRSGRAQVIETDLDEAVEKTMIGLQKKSRVIREEERRIIAYHETGHALAGTFTKGADKVH
HHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCHHHCCCCCCCCCEE
KITIIPRGTSALGYTFHIPEDDRHIVTEQQLLAEVDVLLSGRAAEFVAFGEVSTGAGNDI
EEEEEECCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCCCCCCH
SRATDIVRKMITDYGMSEKFQNVALTRRGTGYLAEPQLAREYSECTQQYVDEEVARVLAE
HHHHHHHHHHHHHCCCHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
RYRAVVALLTEKKELLEYIATRLLERETIERDEFEEVIRCEHDLEGLKKRLSQQQEGASA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PAQGQSPPS
CCCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Metalloendopeptidases [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9665876