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The map label for this gene is yitG [H]

Identifier: 188586382

GI number: 188586382

Start: 1833354

End: 1834553

Strand: Reverse

Name: yitG [H]

Synonym: Nther_1767

Alternate gene names: 188586382

Gene position: 1834553-1833354 (Counterclockwise)

Preceding gene: 188586383

Following gene: 188586380

Centisome position: 57.95

GC content: 33.75

Gene sequence:

>1200_bases
TTGAAAACTATAAGTGCAATTAAAGTAGCAATTTTGTCCGCTTCAAATTATATAACAGTCCTAGTAAATACAGTACTATT
TCCTATTTTCCCTGTCATGGCACAGGCTTTAAATTTAACTTTAAGAGATTTAGCAATCTTAGTCGGTATAGTTTCTTTTC
CATCAGCCCTAATTAATTTAGGAGGTGGGATATTAGCAGATAGATTCGGAAAAAAAATAATTATTGTATTATCCTTAACA
TTATATGGGCTTGGGGGGTTATTAGCTGGACTAAGTATTATATTAATGGAAGAACCTTATCCGGTAATTTTAGTTGGTAG
GCTATTTCAAGGAATAGGTGCGGCAACACCCATGTTTTTATCAGTAGCACTGGTTGGCGATATTTTTCAAAGCTTAGAAA
GAAGTAAAGCTTTGGGTTTTTTAGAAACGGCTAACGGATTAGGGAAAGTTACTAGTCCAATTTTAGGTGCTTTAATTGGT
CTTATTACATGGTATTCCATATTTTTTATTTATCCAATTGTGGCTTTACCGGTTGCTATTGCAACCTGGAAAGTTATAGA
GGAACCTAATGAGAATAAAGGGGTAGATTGGGAGAAACAGAAAAAGGCTTTTCGTCAATTTAAAGATGAATCCAGAATTA
TCACTTTGCTCGTGGCTTTTTTGGTAATATTTATTTTAATTGGTACCATGTTTTGGTTGAGTGATTTTTTAGAAGCTAGA
CTAGAACTAAATCAGATTTTAAGGGGAGTTGTTATATCCTTACCAGCTCTAGCTATGTTACTTACCACATTATTTGCTGA
AAGAATACATAATAAGTTGAATCCTCGCTTTATTATGGGGGGTGGTCTTATATTAACATCAGCTTGTTTAATTGGTATTT
ACCATACCTTAGAAACGATTTTATTTTGGCCATTAATAGTAGCTTTAGGTGTGGGGGCAGGAATTGTATTGCCTTCTGTT
GACATGGTGAGTACTTCAGTAGAAATTAAAGAAATTAGAGGAGTTATGAGTACAATATACGGATCTGCTCGATCTTTGGG
AGGAGCAACTACAACTATTACATTCTCTTACTTGTTGGAATACGGATTACAATTAACATTTTATAGTATAGCAGTGGGAG
GGATAATAGTTGGTTTAATTGTATTATTTAGAATGAATGAAAAAAAATTATTGCCCAAAGAACTGTTACCGGATAAGTGA

Upstream 100 bases:

>100_bases
GGATGAATTTCCCTGCCTTTTTGTATGCAAAAAACTTTCTTAGAGAACACTAAAAAATATGAAATTTAAAATAACAAAGT
CAAAATAGGGGGAAAAAAGT

Downstream 100 bases:

>100_bases
TAGCAGCCAATTGATAACAGGTTTAAAGATTAAAATTAAAATTGATAATAGAAGTAATAGACCAATTAGAGCCACTTTGT
AACAAATTAGCAGTTTAATT

Product: major facilitator superfamily MFS_1

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 399; Mature: 399

Protein sequence:

>399_residues
MKTISAIKVAILSASNYITVLVNTVLFPIFPVMAQALNLTLRDLAILVGIVSFPSALINLGGGILADRFGKKIIIVLSLT
LYGLGGLLAGLSIILMEEPYPVILVGRLFQGIGAATPMFLSVALVGDIFQSLERSKALGFLETANGLGKVTSPILGALIG
LITWYSIFFIYPIVALPVAIATWKVIEEPNENKGVDWEKQKKAFRQFKDESRIITLLVAFLVIFILIGTMFWLSDFLEAR
LELNQILRGVVISLPALAMLLTTLFAERIHNKLNPRFIMGGGLILTSACLIGIYHTLETILFWPLIVALGVGAGIVLPSV
DMVSTSVEIKEIRGVMSTIYGSARSLGGATTTITFSYLLEYGLQLTFYSIAVGGIIVGLIVLFRMNEKKLLPKELLPDK

Sequences:

>Translated_399_residues
MKTISAIKVAILSASNYITVLVNTVLFPIFPVMAQALNLTLRDLAILVGIVSFPSALINLGGGILADRFGKKIIIVLSLT
LYGLGGLLAGLSIILMEEPYPVILVGRLFQGIGAATPMFLSVALVGDIFQSLERSKALGFLETANGLGKVTSPILGALIG
LITWYSIFFIYPIVALPVAIATWKVIEEPNENKGVDWEKQKKAFRQFKDESRIITLLVAFLVIFILIGTMFWLSDFLEAR
LELNQILRGVVISLPALAMLLTTLFAERIHNKLNPRFIMGGGLILTSACLIGIYHTLETILFWPLIVALGVGAGIVLPSV
DMVSTSVEIKEIRGVMSTIYGSARSLGGATTTITFSYLLEYGLQLTFYSIAVGGIIVGLIVLFRMNEKKLLPKELLPDK
>Mature_399_residues
MKTISAIKVAILSASNYITVLVNTVLFPIFPVMAQALNLTLRDLAILVGIVSFPSALINLGGGILADRFGKKIIIVLSLT
LYGLGGLLAGLSIILMEEPYPVILVGRLFQGIGAATPMFLSVALVGDIFQSLERSKALGFLETANGLGKVTSPILGALIG
LITWYSIFFIYPIVALPVAIATWKVIEEPNENKGVDWEKQKKAFRQFKDESRIITLLVAFLVIFILIGTMFWLSDFLEAR
LELNQILRGVVISLPALAMLLTTLFAERIHNKLNPRFIMGGGLILTSACLIGIYHTLETILFWPLIVALGVGAGIVLPSV
DMVSTSVEIKEIRGVMSTIYGSARSLGGATTTITFSYLLEYGLQLTFYSIAVGGIIVGLIVLFRMNEKKLLPKELLPDK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR001958 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 43360; Mature: 43360

Theoretical pI: Translated: 9.55; Mature: 9.55

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTISAIKVAILSASNYITVLVNTVLFPIFPVMAQALNLTLRDLAILVGIVSFPSALINL
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGGILADRFGKKIIIVLSLTLYGLGGLLAGLSIILMEEPYPVILVGRLFQGIGAATPMFL
CCHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHCCCCHHHHH
SVALVGDIFQSLERSKALGFLETANGLGKVTSPILGALIGLITWYSIFFIYPIVALPVAI
HHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATWKVIEEPNENKGVDWEKQKKAFRQFKDESRIITLLVAFLVIFILIGTMFWLSDFLEAR
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LELNQILRGVVISLPALAMLLTTLFAERIHNKLNPRFIMGGGLILTSACLIGIYHTLETI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHH
LFWPLIVALGVGAGIVLPSVDMVSTSVEIKEIRGVMSTIYGSARSLGGATTTITFSYLLE
HHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YGLQLTFYSIAVGGIIVGLIVLFRMNEKKLLPKELLPDK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCC
>Mature Secondary Structure
MKTISAIKVAILSASNYITVLVNTVLFPIFPVMAQALNLTLRDLAILVGIVSFPSALINL
CCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GGGILADRFGKKIIIVLSLTLYGLGGLLAGLSIILMEEPYPVILVGRLFQGIGAATPMFL
CCHHHHHHHCCCEEHHHHHHHHHHHHHHHHHHHHEECCCCCEEEHHHHHHHCCCCHHHHH
SVALVGDIFQSLERSKALGFLETANGLGKVTSPILGALIGLITWYSIFFIYPIVALPVAI
HHHHHHHHHHHHHHHHHCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATWKVIEEPNENKGVDWEKQKKAFRQFKDESRIITLLVAFLVIFILIGTMFWLSDFLEAR
HHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LELNQILRGVVISLPALAMLLTTLFAERIHNKLNPRFIMGGGLILTSACLIGIYHTLETI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCHHHHHHHHHHHHHHHHHHH
LFWPLIVALGVGAGIVLPSVDMVSTSVEIKEIRGVMSTIYGSARSLGGATTTITFSYLLE
HHHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
YGLQLTFYSIAVGGIIVGLIVLFRMNEKKLLPKELLPDK
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]