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The map label for this gene is cobO [H]

Identifier: 188586380

GI number: 188586380

Start: 1831422

End: 1831826

Strand: Reverse

Name: cobO [H]

Synonym: Nther_1765

Alternate gene names: 188586380

Gene position: 1831826-1831422 (Counterclockwise)

Preceding gene: 188586382

Following gene: 188586371

Centisome position: 57.87

GC content: 35.56

Gene sequence:

>405_bases
ATGAAAGGGAGTGAAAATTACGGCGAAATTAAGGCACTAAAACAATTTCCCACAGCTGAAGTGATACTTGCAGGTCGTGA
AGGCTTCATTAATAAAGATGCTCCTGATGTTAAGGATGTAGAGCTAGCTCAGGATGGTTTTGAGAAAGCTATGGATAAAT
TGACATCGAGGGATTATGATATGGTGATTCTAGATGAGCTAAATGTAGCCGTAGATTTTCATTTAATTGAAGTAGAACAA
GTTATGGAATTACTTAATGAACGACCTGAGAATGTTGAATTAGTTATTACGGGAAGAAATGCTTCAGAAGAATTAATCGA
AAAAGCAGACTTAGTAAGTGAAGTTAAAGAAATCAAACATCATTTCCAAAAAGGCGTTGGAGCACGAGAAGGAATTGAAT
ATTAA

Upstream 100 bases:

>100_bases
ACAGGTTTACACAGGAAACGGAAAAGGTAAGACAACAGCTGCTTTTGGACTTGCCTTTCGTTCTTTAGGACATCAAAGAA
AAGTTTGCTTAATTCAGTTT

Downstream 100 bases:

>100_bases
TTTAAAATAAATAATATTTAATATGGAGAGATACAAAATAACAACCGCAGTTTTTTTAAACTGCGGTTTTATTATTTTTT
AAATAAACTAGCTAATTTAT

Product: cob(I)yrinic acid a,c-diamide adenosyltransferase

Products: NA

Alternate protein names: Cob(I)alamin adenosyltransferase; Corrinoid adenosyltransferase [H]

Number of amino acids: Translated: 134; Mature: 134

Protein sequence:

>134_residues
MKGSENYGEIKALKQFPTAEVILAGREGFINKDAPDVKDVELAQDGFEKAMDKLTSRDYDMVILDELNVAVDFHLIEVEQ
VMELLNERPENVELVITGRNASEELIEKADLVSEVKEIKHHFQKGVGAREGIEY

Sequences:

>Translated_134_residues
MKGSENYGEIKALKQFPTAEVILAGREGFINKDAPDVKDVELAQDGFEKAMDKLTSRDYDMVILDELNVAVDFHLIEVEQ
VMELLNERPENVELVITGRNASEELIEKADLVSEVKEIKHHFQKGVGAREGIEY
>Mature_134_residues
MKGSENYGEIKALKQFPTAEVILAGREGFINKDAPDVKDVELAQDGFEKAMDKLTSRDYDMVILDELNVAVDFHLIEVEQ
VMELLNERPENVELVITGRNASEELIEKADLVSEVKEIKHHFQKGVGAREGIEY

Specific function: Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids [H]

COG id: COG2109

COG function: function code H; ATP:corrinoid adenosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the Cob(I)alamin adenosyltransferase family [H]

Homologues:

Organism=Escherichia coli, GI1787525, Length=134, Percent_Identity=33.5820895522388, Blast_Score=77, Evalue=3e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003724 [H]

Pfam domain/function: PF02572 CobA_CobO_BtuR [H]

EC number: =2.5.1.17 [H]

Molecular weight: Translated: 15133; Mature: 15133

Theoretical pI: Translated: 4.28; Mature: 4.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGSENYGEIKALKQFPTAEVILAGREGFINKDAPDVKDVELAQDGFEKAMDKLTSRDYD
CCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
MVILDELNVAVDFHLIEVEQVMELLNERPENVELVITGRNASEELIEKADLVSEVKEIKH
EEEEECCCEEHEEHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
HFQKGVGAREGIEY
HHHHCCCCCCCCCC
>Mature Secondary Structure
MKGSENYGEIKALKQFPTAEVILAGREGFINKDAPDVKDVELAQDGFEKAMDKLTSRDYD
CCCCCCHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCC
MVILDELNVAVDFHLIEVEQVMELLNERPENVELVITGRNASEELIEKADLVSEVKEIKH
EEEEECCCEEHEEHHHHHHHHHHHHHCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHH
HFQKGVGAREGIEY
HHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1655697; 1917862 [H]