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The map label for this gene is kamA [H]

Identifier: 188586383

GI number: 188586383

Start: 1834681

End: 1835919

Strand: Reverse

Name: kamA [H]

Synonym: Nther_1768

Alternate gene names: 188586383

Gene position: 1835919-1834681 (Counterclockwise)

Preceding gene: 188586385

Following gene: 188586382

Centisome position: 58.0

GC content: 38.1

Gene sequence:

>1239_bases
ATGAGTAAAGATGCCAGAACTATTTCTAACAAAAGAGCTCAAGAACTGAAGGACAGTATTCAAGACTTTTTAGAAGCTAG
AGAACATATTGTAACAGGAGAAAAAATTAGTGATGAGCTTGCCAGAAGGCGAAGTCTGATTTTGGAATTGTTTAATGCTT
CGGAGCAAGATTGGAGCGACTGGAAATGGCAGTTGCAAAACAGAATATCTGATGTTGAGACTTTAGAGAAAATTCTCAAT
TTAACCGAGAGTGAAAGACAAGAAATCGAACAAGTAGGTAAAGATTACAGATGGGCTGTTTCACCATATTATGCTAGTTT
GATGGATCCTGATGATCCAGAATGTCCAGTAAGAAAGCAATCCATACCTTCTGCACAAGAGGTGAAAGATAAAGCTGGGG
TTACCGATCCAATGGCCGAGGAATTTACTAATCCGGCTGGGAATGTTACCAGGCGATACCCTGACAGATTAATAATAAAT
GTCACCAATCAGTGCGCTATGTACTGTCGACACTGTCAAAGAAAAAGAAATATTGGTGAGGTCGATAAGCCAACTCCTAA
AGATGTACTAGAAGAGTCAATAGAGTACGTAAAAAATCATGCTGAAATCAGAGATGTTTTATTGACCGGCGGGGATGCAT
TCATGTTGTCAGATGAAACTCTTGATTGGCTTTTAACTGAATTGAGGAAAATACCTCATGTAGAAATTATAAGATTAGGT
AGTAGGACCCCGGTTACAATGCCTCAGAGAATAACTCAAAATCTTTGTGACATTTTAACTAAGCATTTACCTTTATATGT
AAATACCCAGTATAACCACCCTAAAGAATTGACTGCAGAAGCTAAAAAGGCGACCTTTAAGCTAGCTAGAGCAGGTGTTG
GTTTAGGTAATCAAGCAGTTCTTCTCAACACCATTAATAATGACCCCCATGTAATGAAAACTCTTTGTCATGAGCTATTA
AAGGGGATGGTAAGACCTTATTATATTTTCCATGCTAAAAAGGTAAAGGGAACAACCCATTTCAATACTAGAGTTGAGGA
TGGATTAGAGATTTTAGAAAAGATGAGAGGCTATACATCTGGTATGGCAATTCCATCCTACATTATTAACGCACCGGATG
GTCACGGAAAGACACCCATAGTTCCGGAATACATGATTTCTCAAGGTAGAGATAAAGTGTATATCCGCACTTGGGAAAAT
AGAGTTTTTGAATATCCTAATGATGCTCCAGAACAATAA

Upstream 100 bases:

>100_bases
TAGGTAGTTGATAAAATAATAGGAAGGAATCTCTAAAATTTTGCAGAATTATTAACAGAAGGAAAACTTCGTGTATCTAA
AAAGTAAAGGAGGGATGCAG

Downstream 100 bases:

>100_bases
ATAATGGTTTTGAAAGTGCTTAGGCAGGGATGAATTTCCCTGCCTTTTTGTATGCAAAAAACTTTCTTAGAGAACACTAA
AAAATATGAAATTTAAAATA

Product: L-lysine 2,3-aminomutase

Products: NA

Alternate protein names: LAM; KAM [H]

Number of amino acids: Translated: 412; Mature: 411

Protein sequence:

>412_residues
MSKDARTISNKRAQELKDSIQDFLEAREHIVTGEKISDELARRRSLILELFNASEQDWSDWKWQLQNRISDVETLEKILN
LTESERQEIEQVGKDYRWAVSPYYASLMDPDDPECPVRKQSIPSAQEVKDKAGVTDPMAEEFTNPAGNVTRRYPDRLIIN
VTNQCAMYCRHCQRKRNIGEVDKPTPKDVLEESIEYVKNHAEIRDVLLTGGDAFMLSDETLDWLLTELRKIPHVEIIRLG
SRTPVTMPQRITQNLCDILTKHLPLYVNTQYNHPKELTAEAKKATFKLARAGVGLGNQAVLLNTINNDPHVMKTLCHELL
KGMVRPYYIFHAKKVKGTTHFNTRVEDGLEILEKMRGYTSGMAIPSYIINAPDGHGKTPIVPEYMISQGRDKVYIRTWEN
RVFEYPNDAPEQ

Sequences:

>Translated_412_residues
MSKDARTISNKRAQELKDSIQDFLEAREHIVTGEKISDELARRRSLILELFNASEQDWSDWKWQLQNRISDVETLEKILN
LTESERQEIEQVGKDYRWAVSPYYASLMDPDDPECPVRKQSIPSAQEVKDKAGVTDPMAEEFTNPAGNVTRRYPDRLIIN
VTNQCAMYCRHCQRKRNIGEVDKPTPKDVLEESIEYVKNHAEIRDVLLTGGDAFMLSDETLDWLLTELRKIPHVEIIRLG
SRTPVTMPQRITQNLCDILTKHLPLYVNTQYNHPKELTAEAKKATFKLARAGVGLGNQAVLLNTINNDPHVMKTLCHELL
KGMVRPYYIFHAKKVKGTTHFNTRVEDGLEILEKMRGYTSGMAIPSYIINAPDGHGKTPIVPEYMISQGRDKVYIRTWEN
RVFEYPNDAPEQ
>Mature_411_residues
SKDARTISNKRAQELKDSIQDFLEAREHIVTGEKISDELARRRSLILELFNASEQDWSDWKWQLQNRISDVETLEKILNL
TESERQEIEQVGKDYRWAVSPYYASLMDPDDPECPVRKQSIPSAQEVKDKAGVTDPMAEEFTNPAGNVTRRYPDRLIINV
TNQCAMYCRHCQRKRNIGEVDKPTPKDVLEESIEYVKNHAEIRDVLLTGGDAFMLSDETLDWLLTELRKIPHVEIIRLGS
RTPVTMPQRITQNLCDILTKHLPLYVNTQYNHPKELTAEAKKATFKLARAGVGLGNQAVLLNTINNDPHVMKTLCHELLK
GMVRPYYIFHAKKVKGTTHFNTRVEDGLEILEKMRGYTSGMAIPSYIINAPDGHGKTPIVPEYMISQGRDKVYIRTWENR
VFEYPNDAPEQ

Specific function: Catalyzes the interconversion of L-alpha-lysine and L- beta-lysine [H]

COG id: COG1509

COG function: function code E; Lysine 2,3-aminomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the KamA family [H]

Homologues:

Organism=Escherichia coli, GI1790589, Length=324, Percent_Identity=30.2469135802469, Blast_Score=166, Evalue=2e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003739
- InterPro:   IPR022459
- InterPro:   IPR007197 [H]

Pfam domain/function: PF04055 Radical_SAM [H]

EC number: =5.4.3.2 [H]

Molecular weight: Translated: 47395; Mature: 47263

Theoretical pI: Translated: 6.59; Mature: 6.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKDARTISNKRAQELKDSIQDFLEAREHIVTGEKISDELARRRSLILELFNASEQDWSD
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
WKWQLQNRISDVETLEKILNLTESERQEIEQVGKDYRWAVSPYYASLMDPDDPECPVRKQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECHHHHHHCCCCCCCCCCCCC
SIPSAQEVKDKAGVTDPMAEEFTNPAGNVTRRYPDRLIINVTNQCAMYCRHCQRKRNIGE
CCCCHHHHHHHCCCCCHHHHHHCCCCCCCHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCC
VDKPTPKDVLEESIEYVKNHAEIRDVLLTGGDAFMLSDETLDWLLTELRKIPHVEIIRLG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCEEEEEEC
SRTPVTMPQRITQNLCDILTKHLPLYVNTQYNHPKELTAEAKKATFKLARAGVGLGNQAV
CCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
LLNTINNDPHVMKTLCHELLKGMVRPYYIFHAKKVKGTTHFNTRVEDGLEILEKMRGYTS
EEEECCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHCHHC
GMAIPSYIINAPDGHGKTPIVPEYMISQGRDKVYIRTWENRVFEYPNDAPEQ
CCCCCHHEEECCCCCCCCCCCHHHHHHCCCCEEEEEECCCHHEECCCCCCCC
>Mature Secondary Structure 
SKDARTISNKRAQELKDSIQDFLEAREHIVTGEKISDELARRRSLILELFNASEQDWSD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCHHH
WKWQLQNRISDVETLEKILNLTESERQEIEQVGKDYRWAVSPYYASLMDPDDPECPVRKQ
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCEEEECHHHHHHCCCCCCCCCCCCC
SIPSAQEVKDKAGVTDPMAEEFTNPAGNVTRRYPDRLIINVTNQCAMYCRHCQRKRNIGE
CCCCHHHHHHHCCCCCHHHHHHCCCCCCCHHHCCCEEEEEEHHHHHHHHHHHHHHCCCCC
VDKPTPKDVLEESIEYVKNHAEIRDVLLTGGDAFMLSDETLDWLLTELRKIPHVEIIRLG
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECHHHHHHHHHHHHHCCCEEEEEEC
SRTPVTMPQRITQNLCDILTKHLPLYVNTQYNHPKELTAEAKKATFKLARAGVGLGNQAV
CCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCEE
LLNTINNDPHVMKTLCHELLKGMVRPYYIFHAKKVKGTTHFNTRVEDGLEILEKMRGYTS
EEEECCCCHHHHHHHHHHHHHHHHCCEEEEEHHHHCCCCCCCCHHHHHHHHHHHHHCHHC
GMAIPSYIINAPDGHGKTPIVPEYMISQGRDKVYIRTWENRVFEYPNDAPEQ
CCCCCHHEEECCCCCCCCCCCHHHHHHCCCCEEEEEECCCHHEECCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10629195 [H]