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The map label for this gene is yfnA [H]

Identifier: 188586350

GI number: 188586350

Start: 1799697

End: 1800962

Strand: Reverse

Name: yfnA [H]

Synonym: Nther_1733

Alternate gene names: 188586350

Gene position: 1800962-1799697 (Counterclockwise)

Preceding gene: 188586351

Following gene: 188586349

Centisome position: 56.89

GC content: 35.39

Gene sequence:

>1266_bases
ATGATAGTTGGAACAGTTGTTGGAGCAGGAATTTATATTATCATTGGCCCCTTAGCAGTTTCAGTAGGACCAGGCTTGAT
GATATCGTATTTAATTGCTCTGTTAATTGCAGCTGCATCATCCTTTTGTTATGCTCAAGTGGCTGCTATTTATCCTACTA
CAGCAGCTACTTACAGGTATGCCAGAATGTTTTATCCTGAAACTATTGGATTTTTAATGGGTTGGTTAAGGTTTATGACT
TCTTTTTACGGTTTAGCATTAATGGCTAGTGGTTTTACTGAGTACTTTGATAGTCCCTGGGGGATTGATAATAGAATTAT
TGCAGCTGTAATTTTAACGATTTTTTATGTAGTTAATGCCTTTGGAATTAAAACCACCCAACTGGTACAGAGTGTTTTAG
TGACTATAGTAGTTGCTGGTTTGATTGTTTTCTCTGGAGGAGGATTAGCTGAAATTAATTTGGATAACTTAACACCAATG
ACTGAAGCGGGTATGGGTACAATTTTTGGTGGCGCATTAACTGCTTTTTTTGCCTATACTGGTATGTACTTTGTGGCTGA
GATTGGCGATGAAATTGAAGAATCAGATAAAAATATTCCCAGAGCAATTATTATTGCTTCAATAATAATTGGACTTTTGT
ATTTAAGCACTACTTTGGTGTTTTCAGGAGCATTAGGTTGGGATACTATTAAGGCTGCTGAACCCAACTTAGCAGAAGCT
GCTCAAATTATTTTCCCGGGATGGACTTTTTATTTTATACAGTTGAGTGGCGTAGTAGCTGTAATTATGCCCATTAATTC
AATTTATGCTGCCAGTTGTAGACTACTAGCTAGTTTATCTGAAGACGGTTATATGCCCGTAATTTTAGCTAAGAAAAACC
GTTTTAATGTTCCTGGTATAGCTTTGACAGTAATTTATATTTTAGGGATATTGATTGTTTCTCTAGATTTATCAATTTTA
TATTTGGGAGCGATTAGTTCATTAGTGACTTTAATTGGAATGGCCTTGGTAGCTGGTGCCGGGTTAAAGATACTTGCCCA
GGAGCCAGATAAACTGAAAGAGGCACCTTTTACTCTTTCCCCTCGAGTAATGATAGGATTGGGAATATTCACCATTATTG
CAGTGATCTGTTTAGCGGTATTTTCTTTCATGGAGGATCCTTTAATTTTGTATTCTTTATTTATATGGATTGGTTTGGGT
TTAATATATTTTAAAATTAGACAATATTATGCTAAAACAAAAGGCTATCAAAACTTTTATGGATAA

Upstream 100 bases:

>100_bases
TATATCTAAAATTTAAATATCGGGGGTGTTGACAATTACTGCTTCCAATAAGAAAGTTGATTCACAACAATATCAAATTA
GCTTGCTCGGAGCGGTTATT

Downstream 100 bases:

>100_bases
TGAATTTAATAGAAAATGGTGGTGAGATTATGGTTAAAAATCCCAAAGGTTTACTGGCTTTGATTGGTAATCCAGTGGGG
CACTCTCTTTCTCCTGTGAT

Product: amino acid permease-associated region

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 421; Mature: 421

Protein sequence:

>421_residues
MIVGTVVGAGIYIIIGPLAVSVGPGLMISYLIALLIAAASSFCYAQVAAIYPTTAATYRYARMFYPETIGFLMGWLRFMT
SFYGLALMASGFTEYFDSPWGIDNRIIAAVILTIFYVVNAFGIKTTQLVQSVLVTIVVAGLIVFSGGGLAEINLDNLTPM
TEAGMGTIFGGALTAFFAYTGMYFVAEIGDEIEESDKNIPRAIIIASIIIGLLYLSTTLVFSGALGWDTIKAAEPNLAEA
AQIIFPGWTFYFIQLSGVVAVIMPINSIYAASCRLLASLSEDGYMPVILAKKNRFNVPGIALTVIYILGILIVSLDLSIL
YLGAISSLVTLIGMALVAGAGLKILAQEPDKLKEAPFTLSPRVMIGLGIFTIIAVICLAVFSFMEDPLILYSLFIWIGLG
LIYFKIRQYYAKTKGYQNFYG

Sequences:

>Translated_421_residues
MIVGTVVGAGIYIIIGPLAVSVGPGLMISYLIALLIAAASSFCYAQVAAIYPTTAATYRYARMFYPETIGFLMGWLRFMT
SFYGLALMASGFTEYFDSPWGIDNRIIAAVILTIFYVVNAFGIKTTQLVQSVLVTIVVAGLIVFSGGGLAEINLDNLTPM
TEAGMGTIFGGALTAFFAYTGMYFVAEIGDEIEESDKNIPRAIIIASIIIGLLYLSTTLVFSGALGWDTIKAAEPNLAEA
AQIIFPGWTFYFIQLSGVVAVIMPINSIYAASCRLLASLSEDGYMPVILAKKNRFNVPGIALTVIYILGILIVSLDLSIL
YLGAISSLVTLIGMALVAGAGLKILAQEPDKLKEAPFTLSPRVMIGLGIFTIIAVICLAVFSFMEDPLILYSLFIWIGLG
LIYFKIRQYYAKTKGYQNFYG
>Mature_421_residues
MIVGTVVGAGIYIIIGPLAVSVGPGLMISYLIALLIAAASSFCYAQVAAIYPTTAATYRYARMFYPETIGFLMGWLRFMT
SFYGLALMASGFTEYFDSPWGIDNRIIAAVILTIFYVVNAFGIKTTQLVQSVLVTIVVAGLIVFSGGGLAEINLDNLTPM
TEAGMGTIFGGALTAFFAYTGMYFVAEIGDEIEESDKNIPRAIIIASIIIGLLYLSTTLVFSGALGWDTIKAAEPNLAEA
AQIIFPGWTFYFIQLSGVVAVIMPINSIYAASCRLLASLSEDGYMPVILAKKNRFNVPGIALTVIYILGILIVSLDLSIL
YLGAISSLVTLIGMALVAGAGLKILAQEPDKLKEAPFTLSPRVMIGLGIFTIIAVICLAVFSFMEDPLILYSLFIWIGLG
LIYFKIRQYYAKTKGYQNFYG

Specific function: Unknown

COG id: COG0531

COG function: function code E; Amino acid transporters

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Homo sapiens, GI181337167, Length=265, Percent_Identity=27.5471698113208, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI258645169, Length=422, Percent_Identity=24.1706161137441, Blast_Score=76, Evalue=7e-14,
Organism=Homo sapiens, GI4507047, Length=401, Percent_Identity=24.1895261845387, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI258614005, Length=424, Percent_Identity=24.5283018867925, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI114326544, Length=398, Percent_Identity=24.1206030150754, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI114326550, Length=398, Percent_Identity=24.1206030150754, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI258614003, Length=424, Percent_Identity=24.5283018867925, Blast_Score=75, Evalue=2e-13,
Organism=Homo sapiens, GI186910308, Length=385, Percent_Identity=24.1558441558442, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI186910306, Length=385, Percent_Identity=24.1558441558442, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI186910304, Length=385, Percent_Identity=24.1558441558442, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI115648063, Length=340, Percent_Identity=23.8235294117647, Blast_Score=66, Evalue=8e-11,
Organism=Homo sapiens, GI115648022, Length=340, Percent_Identity=23.8235294117647, Blast_Score=66, Evalue=8e-11,
Organism=Escherichia coli, GI87082250, Length=332, Percent_Identity=24.0963855421687, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI87081915, Length=392, Percent_Identity=24.234693877551, Blast_Score=65, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17532491, Length=394, Percent_Identity=25.1269035532995, Blast_Score=80, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17531343, Length=381, Percent_Identity=23.3595800524934, Blast_Score=75, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17540018, Length=350, Percent_Identity=22, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17533459, Length=244, Percent_Identity=25.4098360655738, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI24668806, Length=388, Percent_Identity=23.7113402061856, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356285, Length=388, Percent_Identity=23.7113402061856, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24668802, Length=388, Percent_Identity=23.7113402061856, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI281366235, Length=395, Percent_Identity=25.3164556962025, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI116007820, Length=395, Percent_Identity=25.3164556962025, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI45550968, Length=457, Percent_Identity=24.0700218818381, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI19921172, Length=457, Percent_Identity=24.0700218818381, Blast_Score=82, Evalue=1e-15,
Organism=Drosophila melanogaster, GI24667468, Length=316, Percent_Identity=23.4177215189873, Blast_Score=79, Evalue=5e-15,
Organism=Drosophila melanogaster, GI116007818, Length=368, Percent_Identity=25.5434782608696, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI85725152, Length=368, Percent_Identity=25.5434782608696, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI221512776, Length=398, Percent_Identity=23.8693467336683, Blast_Score=76, Evalue=5e-14,
Organism=Drosophila melanogaster, GI24666159, Length=398, Percent_Identity=23.8693467336683, Blast_Score=76, Evalue=6e-14,
Organism=Drosophila melanogaster, GI24651635, Length=409, Percent_Identity=22.9828850855746, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24651633, Length=409, Percent_Identity=22.9828850855746, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI161077963, Length=366, Percent_Identity=25.4098360655738, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI221331183, Length=424, Percent_Identity=22.4056603773585, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17647653, Length=424, Percent_Identity=22.4056603773585, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24664379, Length=424, Percent_Identity=22.4056603773585, Blast_Score=68, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR015606 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 45417; Mature: 45417

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIVGTVVGAGIYIIIGPLAVSVGPGLMISYLIALLIAAASSFCYAQVAAIYPTTAATYRY
CEEEEEHHCCHHEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ARMFYPETIGFLMGWLRFMTSFYGLALMASGFTEYFDSPWGIDNRIIAAVILTIFYVVNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
FGIKTTQLVQSVLVTIVVAGLIVFSGGGLAEINLDNLTPMTEAGMGTIFGGALTAFFAYT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHH
GMYFVAEIGDEIEESDKNIPRAIIIASIIIGLLYLSTTLVFSGALGWDTIKAAEPNLAEA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
AQIIFPGWTFYFIQLSGVVAVIMPINSIYAASCRLLASLSEDGYMPVILAKKNRFNVPGI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHH
ALTVIYILGILIVSLDLSILYLGAISSLVTLIGMALVAGAGLKILAQEPDKLKEAPFTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCC
PRVMIGLGIFTIIAVICLAVFSFMEDPLILYSLFIWIGLGLIYFKIRQYYAKTKGYQNFY
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
G
C
>Mature Secondary Structure
MIVGTVVGAGIYIIIGPLAVSVGPGLMISYLIALLIAAASSFCYAQVAAIYPTTAATYRY
CEEEEEHHCCHHEEEHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
ARMFYPETIGFLMGWLRFMTSFYGLALMASGFTEYFDSPWGIDNRIIAAVILTIFYVVNA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHH
FGIKTTQLVQSVLVTIVVAGLIVFSGGGLAEINLDNLTPMTEAGMGTIFGGALTAFFAYT
CCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHCCCHHHHHHHHHHHHHHH
GMYFVAEIGDEIEESDKNIPRAIIIASIIIGLLYLSTTLVFSGALGWDTIKAAEPNLAEA
HHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCHHHH
AQIIFPGWTFYFIQLSGVVAVIMPINSIYAASCRLLASLSEDGYMPVILAKKNRFNVPGI
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHH
ALTVIYILGILIVSLDLSILYLGAISSLVTLIGMALVAGAGLKILAQEPDKLKEAPFTLS
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCHHHHCCCCCCC
PRVMIGLGIFTIIAVICLAVFSFMEDPLILYSLFIWIGLGLIYFKIRQYYAKTKGYQNFY
CHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9141694; 9384377 [H]