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The map label for this gene is pdxS

Identifier: 188584654

GI number: 188584654

Start: 21504

End: 22391

Strand: Direct

Name: pdxS

Synonym: Nther_0012

Alternate gene names: 188584654

Gene position: 21504-22391 (Clockwise)

Preceding gene: 188584653

Following gene: 188584655

Centisome position: 0.68

GC content: 40.32

Gene sequence:

>888_bases
ATGAATATAGAAAAAGGTACAGAAACAGTAAAAAAAGGTATGGCCCAAATGCAAAAAGGCGGAGTTATCATGGATGTTAC
AACTCCCGAACAGGCTAAAATAGCTGAAAAAGCAGGAGCTGTAGCAGTGATGGCTTTAGAAAAAGTGCCTGCAGATATAA
GAGCTGGTGGTGGAGTAGCACGAATGGCAGATCCTGAGGTTATTAAAAAGATCATGGATGCTGTAAGTATCCCAGTTATG
GCCAAGGCACGAATTGGTCATTTTGTGGAAGCTCGTATTTTGGAAAATTTAGGCGTTGATTATATAGACGAAAGTGAAGT
GCTTACCCCAGCCGATGAATATTATCACATTGATAAAAACAAATTCACTGTCCCTTTTGTATGTGGTGCTAGGAATTTAG
GAGAAGCCTTACGCCGTGTTGGAGAAGGCGCTTCTATGATGAGAACTAAAGGGGAAGCAGGAACGGGTAATGTGGTAGAG
GCTGTACGTCATATAAGAACTGTTATGGATGGTATCAGAAAAGTTCAAAATCTTCCTGATGATGAGTTAATGACTGAAGC
TAAGAATATTGGAGCACCTTATGACCTTATTAAACAAGTTAAAGAAGAGGGAAGATTGCCTGTAGTTAACTTCGCTGCTG
GTGGAGTAGCTACACCTGCCGATGCAGCTTTGATGATGCAATTAGGTGCCGATGGAGTTTTTGTAGGTTCAGGTATATTT
AAATCAGGTGATCCTGAAAAAAGAGCAAAATCTATTGTAGAAGCAACATTAAATTACGATAATTATGATGTGTTGGCTGA
TGTTTCTTCAGGATTGGGTGAAGCGATGGTAGGAATTAATGTATCCGATCTGGAAGAACAGGAAAGGATGCAAAATCGAG
GCTGGTAA

Upstream 100 bases:

>100_bases
TGATTTTTCGGAATCATAACTAAAATAACTTTATATCAATCTTGTTAATGACTAACTATTGTAGTAAAATCAATGTTGAA
TAGAAAAGGAGGGATTATTA

Downstream 100 bases:

>100_bases
ATTGATACAGTGTATAAGAACTAGAAGATTGATAGGAAAATTTTATAAAAATTAGATTAATTTGTATACAAGGTGCTATT
ACAAAACACATGGACATGCA

Product: pyridoxal biosynthesis lyase PdxS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 295; Mature: 295

Protein sequence:

>295_residues
MNIEKGTETVKKGMAQMQKGGVIMDVTTPEQAKIAEKAGAVAVMALEKVPADIRAGGGVARMADPEVIKKIMDAVSIPVM
AKARIGHFVEARILENLGVDYIDESEVLTPADEYYHIDKNKFTVPFVCGARNLGEALRRVGEGASMMRTKGEAGTGNVVE
AVRHIRTVMDGIRKVQNLPDDELMTEAKNIGAPYDLIKQVKEEGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIF
KSGDPEKRAKSIVEATLNYDNYDVLADVSSGLGEAMVGINVSDLEEQERMQNRGW

Sequences:

>Translated_295_residues
MNIEKGTETVKKGMAQMQKGGVIMDVTTPEQAKIAEKAGAVAVMALEKVPADIRAGGGVARMADPEVIKKIMDAVSIPVM
AKARIGHFVEARILENLGVDYIDESEVLTPADEYYHIDKNKFTVPFVCGARNLGEALRRVGEGASMMRTKGEAGTGNVVE
AVRHIRTVMDGIRKVQNLPDDELMTEAKNIGAPYDLIKQVKEEGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIF
KSGDPEKRAKSIVEATLNYDNYDVLADVSSGLGEAMVGINVSDLEEQERMQNRGW
>Mature_295_residues
MNIEKGTETVKKGMAQMQKGGVIMDVTTPEQAKIAEKAGAVAVMALEKVPADIRAGGGVARMADPEVIKKIMDAVSIPVM
AKARIGHFVEARILENLGVDYIDESEVLTPADEYYHIDKNKFTVPFVCGARNLGEALRRVGEGASMMRTKGEAGTGNVVE
AVRHIRTVMDGIRKVQNLPDDELMTEAKNIGAPYDLIKQVKEEGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIF
KSGDPEKRAKSIVEATLNYDNYDVLADVSSGLGEAMVGINVSDLEEQERMQNRGW

Specific function: Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring

COG id: COG0214

COG function: function code H; Pyridoxine biosynthesis enzyme

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxS/SNZ family

Homologues:

Organism=Saccharomyces cerevisiae, GI6323743, Length=290, Percent_Identity=63.1034482758621, Blast_Score=372, Evalue=1e-104,
Organism=Saccharomyces cerevisiae, GI6321049, Length=293, Percent_Identity=63.8225255972696, Blast_Score=367, Evalue=1e-102,
Organism=Saccharomyces cerevisiae, GI6323996, Length=293, Percent_Identity=63.481228668942, Blast_Score=366, Evalue=1e-102,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXS_NATTJ (B2A2Z7)

Other databases:

- EMBL:   CP001034
- RefSeq:   YP_001916199.1
- ProteinModelPortal:   B2A2Z7
- SMR:   B2A2Z7
- GeneID:   6314409
- GenomeReviews:   CP001034_GR
- KEGG:   nth:Nther_0012
- HOGENOM:   HBG292342
- OMA:   ARMSDPD
- ProtClustDB:   PRK04180
- HAMAP:   MF_01824
- InterPro:   IPR013785
- InterPro:   IPR011060
- InterPro:   IPR001852
- Gene3D:   G3DSA:3.20.20.70
- PIRSF:   PIRSF029271
- TIGRFAMs:   TIGR00343

Pfam domain/function: PF01680 SOR_SNZ; SSF51366 RibP_bind_barrel

EC number: NA

Molecular weight: Translated: 31666; Mature: 31666

Theoretical pI: Translated: 4.82; Mature: 4.82

Prosite motif: PS01235 PDXS_SNZ_1; PS51129 PDXS_SNZ_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
5.4 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIEKGTETVKKGMAQMQKGGVIMDVTTPEQAKIAEKAGAVAVMALEKVPADIRAGGGVA
CCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCEEEEHHHHCCCHHHCCCCCC
RMADPEVIKKIMDAVSIPVMAKARIGHFVEARILENLGVDYIDESEVLTPADEYYHIDKN
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHEEECCC
KFTVPFVCGARNLGEALRRVGEGASMMRTKGEAGTGNVVEAVRHIRTVMDGIRKVQNLPD
CEEEEEECCCHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DELMTEAKNIGAPYDLIKQVKEEGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIF
HHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCC
KSGDPEKRAKSIVEATLNYDNYDVLADVSSGLGEAMVGINVSDLEEQERMQNRGW
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNIEKGTETVKKGMAQMQKGGVIMDVTTPEQAKIAEKAGAVAVMALEKVPADIRAGGGVA
CCCCHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHHCCEEEEHHHHCCCHHHCCCCCC
RMADPEVIKKIMDAVSIPVMAKARIGHFVEARILENLGVDYIDESEVLTPADEYYHIDKN
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHEEECCC
KFTVPFVCGARNLGEALRRVGEGASMMRTKGEAGTGNVVEAVRHIRTVMDGIRKVQNLPD
CEEEEEECCCHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCC
DELMTEAKNIGAPYDLIKQVKEEGRLPVVNFAAGGVATPADAALMMQLGADGVFVGSGIF
HHHHHHHHHCCCCHHHHHHHHHCCCCCEEEECCCCCCCCHHHHHHHHHCCCCEEECCCCC
KSGDPEKRAKSIVEATLNYDNYDVLADVSSGLGEAMVGINVSDLEEQERMQNRGW
CCCCHHHHHHHHHHHHHCCCCCHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA