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The map label for this gene is scoA [H]

Identifier: 188527462

GI number: 188527462

Start: 648679

End: 649377

Strand: Reverse

Name: scoA [H]

Synonym: HPSH_03400

Alternate gene names: 188527462

Gene position: 649377-648679 (Counterclockwise)

Preceding gene: 188527463

Following gene: 188527461

Centisome position: 40.37

GC content: 43.92

Gene sequence:

>699_bases
ATGAACAAGGTTATAACCGATTTAGACAAAGCATTGAGCGCTTTAAAAGACGGGGATACTATTTTAGTGGGCGGTTTTGG
GCTGTGCGGGATACCCGAATACGCCATTGATTACATTTATAAGAAAGGCATCAAGGATTTGATTGTCGTGAGCAATAATT
GTGGCGTTGATGACTTTGGGCTTGGCATTCTGTTAGAAAAAAAACAGATTAAAAAGATTATCGCTTCCTATGTGGGGGAA
AATAAGATTTTTGAATCGCAAATGCTGAACGGAGAAATTGAAGTCGTTTTGACACCGCAAGGCACTTTGGCTGAAAACTT
GCGCGCTGGTGGGGCTGGGATACCCGCTTACTACACCCCAACAGGGGTTGGGACTTTGATCGCTCAAGGCAAGGAATCAC
GGGAGTTTAACGGCAAGGAGTATATTTTAGAAAAAGCGATCACAGGCGATTACGGGCTTATCAAAGCCTATAAAAGCGAC
ACTCTTGGGAACTTGGTGTTTAGAAAAACGGCTAGAAACTTTAATCCCTTGTGCGCGATGGCGGCAAAAATATGCGTCGC
TGAAGTGGAAGAAATTGTTCCGGCCGGGGAATTGGACCCAGATGAAATACACTTGCCAGGAATCTATGTGCAACACATCT
ATAAGGGCGAGAAGTTTGAAAAACGGATAGAAAAAATCACGACAAGGAGCGCGAAATGA

Upstream 100 bases:

>100_bases
GAAATGAAAAGAAGCGGTCATGGCGTGGGCTGCGCGTCATTGTGTGTGGGCGGCGGACAAGGGCTATCAGTGGTAGTGGA
ACAAAAATAAGGAGAATGAG

Downstream 100 bases:

>100_bases
GAGAGGTTATCATTAAAAGAGCGGCAAAGGAATTAAAAGAGGGCATGTATGTGAATTTAGGGATAGGCTTGCCCACGCTT
GTGGCTAATGAAGTGAGCGG

Product: 3-oxoacid Coa-transferase, subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNKVITDLDKALSALKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFGLGILLEKKQIKKIIASYVGE
NKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTPTGVGTLIAQGKESREFNGKEYILEKAITGDYGLIKAYKSD
TLGNLVFRKTARNFNPLCAMAAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKITTRSAK

Sequences:

>Translated_232_residues
MNKVITDLDKALSALKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFGLGILLEKKQIKKIIASYVGE
NKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTPTGVGTLIAQGKESREFNGKEYILEKAITGDYGLIKAYKSD
TLGNLVFRKTARNFNPLCAMAAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKITTRSAK
>Mature_232_residues
MNKVITDLDKALSALKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFGLGILLEKKQIKKIIASYVGE
NKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTPTGVGTLIAQGKESREFNGKEYILEKAITGDYGLIKAYKSD
TLGNLVFRKTARNFNPLCAMAAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKITTRSAK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=56.6801619433198, Blast_Score=283, Evalue=1e-76,
Organism=Homo sapiens, GI11545841, Length=232, Percent_Identity=53.0172413793103, Blast_Score=247, Evalue=7e-66,
Organism=Escherichia coli, GI1788551, Length=213, Percent_Identity=42.7230046948357, Blast_Score=197, Evalue=4e-52,
Organism=Caenorhabditis elegans, GI17531517, Length=244, Percent_Identity=50, Blast_Score=241, Evalue=3e-64,
Organism=Drosophila melanogaster, GI21358325, Length=241, Percent_Identity=53.9419087136929, Blast_Score=259, Evalue=1e-69,
Organism=Drosophila melanogaster, GI24655794, Length=241, Percent_Identity=53.9419087136929, Blast_Score=259, Evalue=1e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25324; Mature: 25324

Theoretical pI: Translated: 5.90; Mature: 5.90

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVITDLDKALSALKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFG
CCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCC
LGILLEKKQIKKIIASYVGENKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTP
CEEEECHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCEECC
TGVGTLIAQGKESREFNGKEYILEKAITGDYGLIKAYKSDTLGNLVFRKTARNFNPLCAM
CCHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
AAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKITTRSAK
HHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKVITDLDKALSALKDGDTILVGGFGLCGIPEYAIDYIYKKGIKDLIVVSNNCGVDDFG
CCHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCC
LGILLEKKQIKKIIASYVGENKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTP
CEEEECHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCEECC
TGVGTLIAQGKESREFNGKEYILEKAITGDYGLIKAYKSDTLGNLVFRKTARNFNPLCAM
CCHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
AAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIEKITTRSAK
HHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]