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The map label for this gene is scoB [H]

Identifier: 188527461

GI number: 188527461

Start: 648059

End: 648682

Strand: Reverse

Name: scoB [H]

Synonym: HPSH_03395

Alternate gene names: 188527461

Gene position: 648682-648059 (Counterclockwise)

Preceding gene: 188527462

Following gene: 188527459

Centisome position: 40.33

GC content: 44.39

Gene sequence:

>624_bases
ATGAGAGAGGTTATCATTAAAAGAGCGGCAAAGGAATTAAAAGAGGGCATGTATGTGAATTTAGGGATAGGCTTGCCCAC
GCTTGTGGCTAATGAAGTGAGCGGGATGAATATCGTTTTCCAAAGCGAGAACGGGCTATTAGGGATTGGTGCTTACCCTT
TAGAGGGGGGCGTTGATGCGGATCTCATTAATGCAGGAAAAGAAACCGTAACCGTGGTGCCGGGTGCTTCGTTTTTCAAC
AGCGCGGATTCGTTTGCGATGATTCGTGGGGGGCATATTGATTTAGCGATTTTAGGAGGGATGGAAGTCTCACAAAATGG
GGATTTGGCTAATTGGATGATCCCTAAAAAGCTCATAAAAGGCATGGGAGGGGCTATGGATCTGGTGCATGGTGCTAAAA
AAGTGATTGTCATCATGGAGCATTGCAACAAATACGGGGAGTCTAAAGTGAAAAAAGAATGCTCATTGCCCCTAACAGGA
AAAGGCGTGGTGCATCAATTGATAACGGATTTAGCGGTGTTTGAGTTTTCCAATAACGCCATGAAATTAGTGGAATTGCA
AGAGGGTGTCAGCCTTGATCAAGTGAGAGAAAAAACAGAAGCTGAATTTGAAGTGTGCTTATAG

Upstream 100 bases:

>100_bases
ACCCAGATGAAATACACTTGCCAGGAATCTATGTGCAACACATCTATAAGGGCGAGAAGTTTGAAAAACGGATAGAAAAA
ATCACGACAAGGAGCGCGAA

Downstream 100 bases:

>100_bases
CTTATAAGAGGGGTGTTGATGTTTTTATTAAGGCATTTGACTTCAGCGTGCGTGTTTTTAGCGTCTAAATGTTTGCCGGA
CTCCTTTGTCTTGGTCACTC

Product: succinyl-CoA-transferase subunit B

Products: NA

Alternate protein names: OXCT B; Succinyl CoA:3-oxoacid CoA-transferase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MREVIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGGVDADLINAGKETVTVVPGASFFN
SADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIKGMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTG
KGVVHQLITDLAVFEFSNNAMKLVELQEGVSLDQVREKTEAEFEVCL

Sequences:

>Translated_207_residues
MREVIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGGVDADLINAGKETVTVVPGASFFN
SADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIKGMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTG
KGVVHQLITDLAVFEFSNNAMKLVELQEGVSLDQVREKTEAEFEVCL
>Mature_207_residues
MREVIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGGVDADLINAGKETVTVVPGASFFN
SADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIKGMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTG
KGVVHQLITDLAVFEFSNNAMKLVELQEGVSLDQVREKTEAEFEVCL

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=208, Percent_Identity=57.6923076923077, Blast_Score=240, Evalue=6e-64,
Organism=Homo sapiens, GI11545841, Length=207, Percent_Identity=55.0724637681159, Blast_Score=229, Evalue=1e-60,
Organism=Escherichia coli, GI1788552, Length=209, Percent_Identity=52.1531100478469, Blast_Score=224, Evalue=4e-60,
Organism=Caenorhabditis elegans, GI17531517, Length=207, Percent_Identity=53.6231884057971, Blast_Score=233, Evalue=6e-62,
Organism=Drosophila melanogaster, GI21358325, Length=209, Percent_Identity=56.9377990430622, Blast_Score=238, Evalue=1e-63,
Organism=Drosophila melanogaster, GI24655794, Length=209, Percent_Identity=56.9377990430622, Blast_Score=238, Evalue=2e-63,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 22222; Mature: 22222

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREVIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGGVDA
CHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCH
DLINAGKETVTVVPGASFFNSADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIK
HHHHCCCCEEEEECCCHHHCCCCCEEEEECCCEEEEEECCEEECCCCCCHHHHHHHHHHH
GMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTGKGVVHQLITDLAVFEFSNNA
HCCCHHHHHHCCHHEEEEHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHEEECCCC
MKLVELQEGVSLDQVREKTEAEFEVCL
EEEEEECCCCCHHHHHHHHCCCEEECC
>Mature Secondary Structure
MREVIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGGVDA
CHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCH
DLINAGKETVTVVPGASFFNSADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIK
HHHHCCCCEEEEECCCHHHCCCCCEEEEECCCEEEEEECCEEECCCCCCHHHHHHHHHHH
GMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTGKGVVHQLITDLAVFEFSNNA
HCCCHHHHHHCCHHEEEEHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHEEECCCC
MKLVELQEGVSLDQVREKTEAEFEVCL
EEEEEECCCCCHHHHHHHHCCCEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]