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The map label for this gene is cph2 [H]

Identifier: 187927646

GI number: 187927646

Start: 585332

End: 586831

Strand: Reverse

Name: cph2 [H]

Synonym: Rpic_0546

Alternate gene names: 187927646

Gene position: 586831-585332 (Counterclockwise)

Preceding gene: 187927647

Following gene: 187927645

Centisome position: 14.88

GC content: 63.4

Gene sequence:

>1500_bases
ATGCACCTTCGCCCCCTCGCCCGACGGCTGGCCACATCGGCAGGCCACCATCCCTTTGTTGTTGGTGCGCTGGGGACGCT
GCTCACATTCATTGTCCTGGCAATCAGCGTGCTGACCCTTTGGGCCAACCGCGAAACGGCCATCGAGCACGCACACGACA
CCTCGAAGAATGTCGCTGCCGTTCTGGCCAGCCACATTTCGCGCACCGTTGAATCGGCAGATCAATCGCTGCAGACGCTG
ATAGGCGCACTCGACAAACCCGGCATCCGCAACCTCGATCCGCAGGTTCGGCACGATCTGCTGTTCAGCCCGACGGCCTC
TGCCCGGTATGTCACCGGCATGGGCGTGACCGACGACAAGGGCCAGCTCGTCGACGGATGCTGCTCCTTGACCCACCGCT
GGGATTTCAGCGACCGCGACTACTTTATCGTCCATCGCGAGCACGCAAACCTTGGCCTTTATGTGTCCGGCGTCTATAAG
GCCCGGTCACGCGCAGGCGTGGAGGCCATCGCCCTGAGCCGAAGAATGAACCGACAGGATGGGACGTTTGCCGGCACCGC
GCTAGTGGCGATCGACCTCGATTACTTCCGGCAGCTTCTTGAAAGGCTTGATGTCGGGCCGCGCGGCATCACGGCCATTG
TCCGCACCGACGGCACGCTAATGGCGCGAAATCCGCCCGGCGCAGCCCGCGCGTTCAATCTGAGCAAATCGTTGACGTTC
CCGCGCATGGTGAATCAGGAGTCCGGCTTCTATGTAGCACCGTCGGCCAGCGATGGCGTGGTGCGCCTCTATACGTTTCA
ACGTGTGCCGGGCACCCCCTTCATCGCCGTGGTGGCCCCGGCAATGAGCGATGCCCTTGCAGCTTGGCAGCGGCTGTCAT
GGATCGTAGGGTTGTCGTCGCTGTCGGTGAGTCTTGCGTTCTGCGCAGGTGTCTGGCTCCTGGCTTTTGCGCTGCGGGGC
CGCGTGATGGCGGAAAACCACCTGCGCGAGCTTACGCAAACCGATCCGCTCACCGGGTTGAAGAACAGGCGCGCCCTGGA
TGTCGCGCTGGAGAACGAGTGGGATCGGCTGCAACGGAATGACAGTCGGCTGTCCGTGCTCTTTATCGATGCCGATCACT
TCAAACGCTATAACGACGCGCACGGCCATGCTCAGGGCGACGTCGCGCTTCAGTACCTCGCCCAGTGCATTTCCAAGCAT
GCGCGACGACGCGGCGACCTGGCGGCCCGATACGGCGGAGAGGAATTCGTGGTGCTGTTGCCCGATACGGACGAAGCGGG
TGCCACGCGGATCGCCGAAGCGATCCGTGCCGAAGTGGAAGGCGCCGGCGCGTCCGTCGGCGACGCAGGTTTGGCCCCCT
TCACCGTGAGCGTCGGTTGCGCGACCGCGCGGCGCGCGAGCTTCCCGTCGCTGAACGCATTGACCAAGGCTGCGGACGAT
GCGCTCTACGAAGCCAAGCGTAAAGGCCGCAACCGCATTGACTACGCCACGGTTGGCTAG

Upstream 100 bases:

>100_bases
ACGGCGTGCCCCACACGCATCCAAACCGTCCCCAAGATCGATCGCCCGATGCCTCGTCGACCAGGCTGAGGTGCGGTTTG
TCGTCGCCCAAGACCACGAC

Downstream 100 bases:

>100_bases
CCTCACGTGAGCGCCGCCCCCGATCTACAGACCGAGCAGTCGCGCAAACTGGCCGCCGTCGGAGTTGATCGGCGTCTGGT
ACCTGCCGCCCGAGCCAAAG

Product: diguanylate cyclase

Products: NA

Alternate protein names: Bacteriophytochrome cph2 [H]

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MHLRPLARRLATSAGHHPFVVGALGTLLTFIVLAISVLTLWANRETAIEHAHDTSKNVAAVLASHISRTVESADQSLQTL
IGALDKPGIRNLDPQVRHDLLFSPTASARYVTGMGVTDDKGQLVDGCCSLTHRWDFSDRDYFIVHREHANLGLYVSGVYK
ARSRAGVEAIALSRRMNRQDGTFAGTALVAIDLDYFRQLLERLDVGPRGITAIVRTDGTLMARNPPGAARAFNLSKSLTF
PRMVNQESGFYVAPSASDGVVRLYTFQRVPGTPFIAVVAPAMSDALAAWQRLSWIVGLSSLSVSLAFCAGVWLLAFALRG
RVMAENHLRELTQTDPLTGLKNRRALDVALENEWDRLQRNDSRLSVLFIDADHFKRYNDAHGHAQGDVALQYLAQCISKH
ARRRGDLAARYGGEEFVVLLPDTDEAGATRIAEAIRAEVEGAGASVGDAGLAPFTVSVGCATARRASFPSLNALTKAADD
ALYEAKRKGRNRIDYATVG

Sequences:

>Translated_499_residues
MHLRPLARRLATSAGHHPFVVGALGTLLTFIVLAISVLTLWANRETAIEHAHDTSKNVAAVLASHISRTVESADQSLQTL
IGALDKPGIRNLDPQVRHDLLFSPTASARYVTGMGVTDDKGQLVDGCCSLTHRWDFSDRDYFIVHREHANLGLYVSGVYK
ARSRAGVEAIALSRRMNRQDGTFAGTALVAIDLDYFRQLLERLDVGPRGITAIVRTDGTLMARNPPGAARAFNLSKSLTF
PRMVNQESGFYVAPSASDGVVRLYTFQRVPGTPFIAVVAPAMSDALAAWQRLSWIVGLSSLSVSLAFCAGVWLLAFALRG
RVMAENHLRELTQTDPLTGLKNRRALDVALENEWDRLQRNDSRLSVLFIDADHFKRYNDAHGHAQGDVALQYLAQCISKH
ARRRGDLAARYGGEEFVVLLPDTDEAGATRIAEAIRAEVEGAGASVGDAGLAPFTVSVGCATARRASFPSLNALTKAADD
ALYEAKRKGRNRIDYATVG
>Mature_499_residues
MHLRPLARRLATSAGHHPFVVGALGTLLTFIVLAISVLTLWANRETAIEHAHDTSKNVAAVLASHISRTVESADQSLQTL
IGALDKPGIRNLDPQVRHDLLFSPTASARYVTGMGVTDDKGQLVDGCCSLTHRWDFSDRDYFIVHREHANLGLYVSGVYK
ARSRAGVEAIALSRRMNRQDGTFAGTALVAIDLDYFRQLLERLDVGPRGITAIVRTDGTLMARNPPGAARAFNLSKSLTF
PRMVNQESGFYVAPSASDGVVRLYTFQRVPGTPFIAVVAPAMSDALAAWQRLSWIVGLSSLSVSLAFCAGVWLLAFALRG
RVMAENHLRELTQTDPLTGLKNRRALDVALENEWDRLQRNDSRLSVLFIDADHFKRYNDAHGHAQGDVALQYLAQCISKH
ARRRGDLAARYGGEEFVVLLPDTDEAGATRIAEAIRAEVEGAGASVGDAGLAPFTVSVGCATARRASFPSLNALTKAADD
ALYEAKRKGRNRIDYATVG

Specific function: Photoreceptor which exists in two forms that are reversibly interconvertible by light:the R form that absorbs maximally in the red region of the spectrum and the FR form that absorbs maximally in the far-red region [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 GGDEF domains [H]

Homologues:

Organism=Escherichia coli, GI87081881, Length=169, Percent_Identity=42.603550295858, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI145693134, Length=160, Percent_Identity=38.125, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787262, Length=166, Percent_Identity=36.7469879518072, Blast_Score=95, Evalue=1e-20,
Organism=Escherichia coli, GI1786584, Length=169, Percent_Identity=33.1360946745562, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1787802, Length=202, Percent_Identity=33.6633663366337, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI87082007, Length=159, Percent_Identity=35.2201257861635, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081974, Length=161, Percent_Identity=32.2981366459627, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787816, Length=165, Percent_Identity=33.9393939393939, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87081977, Length=154, Percent_Identity=31.1688311688312, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1787541, Length=174, Percent_Identity=32.7586206896552, Blast_Score=70, Evalue=4e-13,
Organism=Escherichia coli, GI1788381, Length=176, Percent_Identity=32.9545454545455, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788956, Length=158, Percent_Identity=32.9113924050633, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR003018
- InterPro:   IPR016132
- InterPro:   IPR001294
- InterPro:   IPR013515 [H]

Pfam domain/function: PF00563 EAL; PF01590 GAF; PF00990 GGDEF; PF00360 Phytochrome [H]

EC number: NA

Molecular weight: Translated: 54285; Mature: 54285

Theoretical pI: Translated: 9.09; Mature: 9.09

Prosite motif: PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLRPLARRLATSAGHHPFVVGALGTLLTFIVLAISVLTLWANRETAIEHAHDTSKNVAA
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHH
VLASHISRTVESADQSLQTLIGALDKPGIRNLDPQVRHDLLFSPTASARYVTGMGVTDDK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEECCCCCCEEEEECCCCCCC
GQLVDGCCSLTHRWDFSDRDYFIVHREHANLGLYVSGVYKARSRAGVEAIALSRRMNRQD
CHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHCCHHHHHHHHHCCCCC
GTFAGTALVAIDLDYFRQLLERLDVGPRGITAIVRTDGTLMARNPPGAARAFNLSKSLTF
CCEECEEEEEEEHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCHHEECCHHCCCC
PRMVNQESGFYVAPSASDGVVRLYTFQRVPGTPFIAVVAPAMSDALAAWQRLSWIVGLSS
CHHHCCCCCEEECCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
LSVSLAFCAGVWLLAFALRGRVMAENHLRELTQTDPLTGLKNRRALDVALENEWDRLQRN
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHCC
DSRLSVLFIDADHFKRYNDAHGHAQGDVALQYLAQCISKHARRRGDLAARYGGEEFVVLL
CCEEEEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEE
PDTDEAGATRIAEAIRAEVEGAGASVGDAGLAPFTVSVGCATARRASFPSLNALTKAADD
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHCCCCCHHHHHHHHHH
ALYEAKRKGRNRIDYATVG
HHHHHHHCCCCCCCEECCC
>Mature Secondary Structure
MHLRPLARRLATSAGHHPFVVGALGTLLTFIVLAISVLTLWANRETAIEHAHDTSKNVAA
CCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCHHHHHH
VLASHISRTVESADQSLQTLIGALDKPGIRNLDPQVRHDLLFSPTASARYVTGMGVTDDK
HHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHEEECCCCCCEEEEECCCCCCC
GQLVDGCCSLTHRWDFSDRDYFIVHREHANLGLYVSGVYKARSRAGVEAIALSRRMNRQD
CHHHHHHHHHHCCCCCCCCCEEEEEECCCCCEEEEEHHHHHHHHCCHHHHHHHHHCCCCC
GTFAGTALVAIDLDYFRQLLERLDVGPRGITAIVRTDGTLMARNPPGAARAFNLSKSLTF
CCEECEEEEEEEHHHHHHHHHHCCCCCCCEEEEEECCCEEEECCCCCCHHEECCHHCCCC
PRMVNQESGFYVAPSASDGVVRLYTFQRVPGTPFIAVVAPAMSDALAAWQRLSWIVGLSS
CHHHCCCCCEEECCCCCCCEEEEEEEECCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHH
LSVSLAFCAGVWLLAFALRGRVMAENHLRELTQTDPLTGLKNRRALDVALENEWDRLQRN
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCEEEEEECCCHHHHHCC
DSRLSVLFIDADHFKRYNDAHGHAQGDVALQYLAQCISKHARRRGDLAARYGGEEFVVLL
CCEEEEEEEEHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHHCCCCEEEEEE
PDTDEAGATRIAEAIRAEVEGAGASVGDAGLAPFTVSVGCATARRASFPSLNALTKAADD
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEEECCHHHHHCCCCCHHHHHHHHHH
ALYEAKRKGRNRIDYATVG
HHHHHHHCCCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8590279; 8905231; 10978170; 11063585 [H]