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The map label for this gene is qseC [H]

Identifier: 187927569

GI number: 187927569

Start: 502392

End: 503987

Strand: Reverse

Name: qseC [H]

Synonym: Rpic_0469

Alternate gene names: 187927569

Gene position: 503987-502392 (Counterclockwise)

Preceding gene: 187927570

Following gene: 187927568

Centisome position: 12.78

GC content: 67.29

Gene sequence:

>1596_bases
ATGGGTGATCGGCTGGCCTGGCCGTGGCGTCGGCATCGCGCATCGCTGCGCGAACGCACCGACGCGGTGCCCGGAGCCGA
TGGCCGCGATGGCCGCGATGGCCGCGATGGCCGCGATGGCGGCGGCGACCTCGCCGACACCCTCCCCCACCTCGAAGACG
ACGCCACGCGGCCCGCCGCCCGATCCCTCTTCGGCGAAATTCTGGACTGGATGCTTGCGCCGCTGCTGTTGCTGTGGCCG
ATGAGCATTGCGGTGACGTACCTGGTCGCCAAGTCGATTGCGAATGCGCCATATGACCGCGCACTGGAATCGAGCGCGAT
CGTGCTCAGCCAGCAACTGCGCGAGGTGAATGGGCGCGTGACGCTGCAACTGCCGATCTCGGCGCGCGAAATCCTGCGTG
CGGACGAAACCGACAACATCTACTACCAGGTGCTCGGCACCAACGGCGAGTTTGTCTCCGGGGACCGCGACCTCCCGCTG
CCGCCCGAAGAAGACGCCAACGCCGGCGGCCTCGTGCAACTGCGCGACGACCACATCCATGGCGCGGAGATCCGTGTTGC
GTATACCTTCGTGCAGCGGCCGGGCTCCGGCGGCAAACCCGCGCTGGTGCAAGTGGCGGAGACGCTCGACAAGCGCGCAC
AACTCGCCAACGAAATCATCAAGGGCGTGATCCTGCCGCAGTTTGTGATCCTGCCGTTGGCGGTGATCCTGGTGTGGTTT
GGCCTCTCGCGCGGGCTGGCACCGCTCAATGCGATTCAGGAACGCATCCGCGCTCGCAACCCGGGCGACACCAGCCCCAT
CGACGAAGGCGCGGCGCCGCAGGAGCTGACGCCGCTGGTGGCATCGTTCAATGATCTGCTCGGGCGGCTGGAGCAATCGG
TGCACACGCAGAAGCGCTTCATTGCGGATGCCGCGCATCAGATGAAGACGCCGCTGGCCGGCCTGCGCATGCAGGCAGAG
CTGGCACAGCGCGAGCAGTCGCCCGACGAGCTGCGCCGCACGCTCGCACATATCGCCGACAGCTCGGATCGCACCGCGCA
CCTCGTCAAGCAGTTGCTTTCGCTGGCACGCATGGAAAACATGGGCGCCACCGACGGTATGGTGCCGCTGGATATCTGCG
CGCTGTCGCGCCGAGTGGTGGCCGACTGGCTGCCCAAGGCGTGGGCCAAGCAGATCGACCTCGGCTTCGAGGAGCCGGGG
CCGCCCGTCACGATTTCGGGCAATGCGACGATGCTCGCCGAGATGCTCAACAACCTGCTCGACAACGCGATCCGCTACAC
GCCCGACGGCGGACATGTCACCGTGCGCGTGACCACCGCGCCGTTCGAGCCGTTCGTCTTCATCGACGTGGATGACACCG
GCCCCGGCATCCCCGTGGCCGAGCGCGAACGCGTGATGCAGCGCTTCTACCGCATCCTCGGCACGCAAGCCGAGGGCAGC
GGGCTGGGCCTGGCCATCGTGCGCGAGATCGTGCAGCAGCACGGCGGGGACATCGAGGTGCTCGACAACGTGTATCAAGT
GTCGCCGCGGCTGGCGGGGGCGCGCTTTCGCATCACGCTGCACCGCTGCTCGCCGAGCGAGGAACCCAACGCATGA

Upstream 100 bases:

>100_bases
AAGAAGATCGAAGTGGAAGGCATCCGCATCGCCACCGTGCGCGGGCTGGGCTATTGCCTGGAACGCACGGCCACCCCAAC
CACCACCGCGACCGCTGCCC

Downstream 100 bases:

>100_bases
GCATCACGCCCGGAACGCCCGCGCGCCGGCGGTGGATCGCCAATATGCGCTGGATCGCGGCACTGCTCGCGGTGTGGTTT
GTGGTGACGTTCGTGGTCGC

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 531; Mature: 530

Protein sequence:

>531_residues
MGDRLAWPWRRHRASLRERTDAVPGADGRDGRDGRDGRDGGGDLADTLPHLEDDATRPAARSLFGEILDWMLAPLLLLWP
MSIAVTYLVAKSIANAPYDRALESSAIVLSQQLREVNGRVTLQLPISAREILRADETDNIYYQVLGTNGEFVSGDRDLPL
PPEEDANAGGLVQLRDDHIHGAEIRVAYTFVQRPGSGGKPALVQVAETLDKRAQLANEIIKGVILPQFVILPLAVILVWF
GLSRGLAPLNAIQERIRARNPGDTSPIDEGAAPQELTPLVASFNDLLGRLEQSVHTQKRFIADAAHQMKTPLAGLRMQAE
LAQREQSPDELRRTLAHIADSSDRTAHLVKQLLSLARMENMGATDGMVPLDICALSRRVVADWLPKAWAKQIDLGFEEPG
PPVTISGNATMLAEMLNNLLDNAIRYTPDGGHVTVRVTTAPFEPFVFIDVDDTGPGIPVAERERVMQRFYRILGTQAEGS
GLGLAIVREIVQQHGGDIEVLDNVYQVSPRLAGARFRITLHRCSPSEEPNA

Sequences:

>Translated_531_residues
MGDRLAWPWRRHRASLRERTDAVPGADGRDGRDGRDGRDGGGDLADTLPHLEDDATRPAARSLFGEILDWMLAPLLLLWP
MSIAVTYLVAKSIANAPYDRALESSAIVLSQQLREVNGRVTLQLPISAREILRADETDNIYYQVLGTNGEFVSGDRDLPL
PPEEDANAGGLVQLRDDHIHGAEIRVAYTFVQRPGSGGKPALVQVAETLDKRAQLANEIIKGVILPQFVILPLAVILVWF
GLSRGLAPLNAIQERIRARNPGDTSPIDEGAAPQELTPLVASFNDLLGRLEQSVHTQKRFIADAAHQMKTPLAGLRMQAE
LAQREQSPDELRRTLAHIADSSDRTAHLVKQLLSLARMENMGATDGMVPLDICALSRRVVADWLPKAWAKQIDLGFEEPG
PPVTISGNATMLAEMLNNLLDNAIRYTPDGGHVTVRVTTAPFEPFVFIDVDDTGPGIPVAERERVMQRFYRILGTQAEGS
GLGLAIVREIVQQHGGDIEVLDNVYQVSPRLAGARFRITLHRCSPSEEPNA
>Mature_530_residues
GDRLAWPWRRHRASLRERTDAVPGADGRDGRDGRDGRDGGGDLADTLPHLEDDATRPAARSLFGEILDWMLAPLLLLWPM
SIAVTYLVAKSIANAPYDRALESSAIVLSQQLREVNGRVTLQLPISAREILRADETDNIYYQVLGTNGEFVSGDRDLPLP
PEEDANAGGLVQLRDDHIHGAEIRVAYTFVQRPGSGGKPALVQVAETLDKRAQLANEIIKGVILPQFVILPLAVILVWFG
LSRGLAPLNAIQERIRARNPGDTSPIDEGAAPQELTPLVASFNDLLGRLEQSVHTQKRFIADAAHQMKTPLAGLRMQAEL
AQREQSPDELRRTLAHIADSSDRTAHLVKQLLSLARMENMGATDGMVPLDICALSRRVVADWLPKAWAKQIDLGFEEPGP
PVTISGNATMLAEMLNNLLDNAIRYTPDGGHVTVRVTTAPFEPFVFIDVDDTGPGIPVAERERVMQRFYRILGTQAEGSG
LGLAIVREIVQQHGGDIEVLDNVYQVSPRLAGARFRITLHRCSPSEEPNA

Specific function: Member of a two-component regulatory system qseB/qseC. May activate qseB by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=369, Percent_Identity=30.8943089430894, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI1786783, Length=376, Percent_Identity=30.0531914893617, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI1790551, Length=304, Percent_Identity=29.2763157894737, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=28.5714285714286, Blast_Score=102, Evalue=4e-23,
Organism=Escherichia coli, GI1788279, Length=303, Percent_Identity=26.4026402640264, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790346, Length=257, Percent_Identity=31.5175097276265, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790861, Length=333, Percent_Identity=28.8288288288288, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI145693157, Length=223, Percent_Identity=29.1479820627803, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=30.0429184549356, Blast_Score=92, Evalue=7e-20,
Organism=Escherichia coli, GI48994928, Length=248, Percent_Identity=28.6290322580645, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1787374, Length=303, Percent_Identity=26.0726072607261, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1790436, Length=200, Percent_Identity=29.5, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI87082128, Length=292, Percent_Identity=25, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1787894, Length=348, Percent_Identity=24.7126436781609, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1786912, Length=226, Percent_Identity=30.0884955752212, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1789149, Length=216, Percent_Identity=25, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI87081816, Length=234, Percent_Identity=26.0683760683761, Blast_Score=65, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 58215; Mature: 58084

Theoretical pI: Translated: 5.17; Mature: 5.17

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGDRLAWPWRRHRASLRERTDAVPGADGRDGRDGRDGRDGGGDLADTLPHLEDDATRPAA
CCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHH
RSLFGEILDWMLAPLLLLWPMSIAVTYLVAKSIANAPYDRALESSAIVLSQQLREVNGRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEE
TLQLPISAREILRADETDNIYYQVLGTNGEFVSGDRDLPLPPEEDANAGGLVQLRDDHIH
EEEECCCHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCC
GAEIRVAYTFVQRPGSGGKPALVQVAETLDKRAQLANEIIKGVILPQFVILPLAVILVWF
CCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLSRGLAPLNAIQERIRARNPGDTSPIDEGAAPQELTPLVASFNDLLGRLEQSVHTQKRF
HHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IADAAHQMKTPLAGLRMQAELAQREQSPDELRRTLAHIADSSDRTAHLVKQLLSLARMEN
HHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
MGATDGMVPLDICALSRRVVADWLPKAWAKQIDLGFEEPGPPVTISGNATMLAEMLNNLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHH
DNAIRYTPDGGHVTVRVTTAPFEPFVFIDVDDTGPGIPVAERERVMQRFYRILGTQAEGS
HHHEEECCCCCEEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
GLGLAIVREIVQQHGGDIEVLDNVYQVSPRLAGARFRITLHRCSPSEEPNA
CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCC
>Mature Secondary Structure 
GDRLAWPWRRHRASLRERTDAVPGADGRDGRDGRDGRDGGGDLADTLPHLEDDATRPAA
CCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHCCCCCCCCCCHHH
RSLFGEILDWMLAPLLLLWPMSIAVTYLVAKSIANAPYDRALESSAIVLSQQLREVNGRV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEE
TLQLPISAREILRADETDNIYYQVLGTNGEFVSGDRDLPLPPEEDANAGGLVQLRDDHIH
EEEECCCHHHHHHCCCCCCEEEEEECCCCCEECCCCCCCCCCCCCCCCCCEEEEECCCCC
GAEIRVAYTFVQRPGSGGKPALVQVAETLDKRAQLANEIIKGVILPQFVILPLAVILVWF
CCEEEEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GLSRGLAPLNAIQERIRARNPGDTSPIDEGAAPQELTPLVASFNDLLGRLEQSVHTQKRF
HHHCCCCHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHH
IADAAHQMKTPLAGLRMQAELAQREQSPDELRRTLAHIADSSDRTAHLVKQLLSLARMEN
HHHHHHHHHCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHC
MGATDGMVPLDICALSRRVVADWLPKAWAKQIDLGFEEPGPPVTISGNATMLAEMLNNLL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHH
DNAIRYTPDGGHVTVRVTTAPFEPFVFIDVDDTGPGIPVAERERVMQRFYRILGTQAEGS
HHHEEECCCCCEEEEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCCCCCC
GLGLAIVREIVQQHGGDIEVLDNVYQVSPRLAGARFRITLHRCSPSEEPNA
CCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCEEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800; 10675023 [H]