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The map label for this gene is tctD [H]

Identifier: 187927570

GI number: 187927570

Start: 503980

End: 504690

Strand: Reverse

Name: tctD [H]

Synonym: Rpic_0470

Alternate gene names: 187927570

Gene position: 504690-503980 (Counterclockwise)

Preceding gene: 187927581

Following gene: 187927569

Centisome position: 12.8

GC content: 67.37

Gene sequence:

>711_bases
ATGCGCATCCTGATTGCCGAAGACGACGCCACGCTGGCTGACGGGCTCACACGCTCGCTGCGCCAGGCGGGCTACGCCGT
CGACCAAGCCTCCGATGGGGCGACTGCCGACGCGGCGCTGTCCGCGCAAACGGCCCAGACCTATGACCTGCTGATCCTCG
ACGTGGGACTGCCGCGTATGTCGGGGCTGGAGGTCCTTAAGCGCCTGCGCTCGCGCGGGGCCATGCTGCCGGTGCTGATC
CTGACCGCCGCCGACAGCGTGGAAGAACGAGTCAAGGGGCTGGATCTTGGCGCCGACGATTACATGGCCAAACCGTTCGC
GCTGTCCGAGCTGGAAGCGCGCGTGCGTGCGCTGGTGCGGCGCGGCACGGGCGGCGGCGCCACGCTCGTGCGCCATGGGC
CGCTGGCATTCGACCAGGTCGGGCGCATTGCCTATATCCACGATCAGGTGGTGGAACTGTCGGCACGCGAGATCGGGCTG
CTGGAGATTCTGCTGGCGCGCGTGGGCCGCCTGGTGTCGAAAGAGCAACTGGTCGACCATCTGTGCGGCTGGGGCGAAGA
AGTCAGCAACAACGCCATCGAGGTCTACATCCACCGCCTGCGCAAGAAGATCGAAGTGGAAGGCATCCGCATCGCCACCG
TGCGCGGGCTGGGCTATTGCCTGGAACGCACGGCCACCCCAACCACCACCGCGACCGCTGCCCATGGGTGA

Upstream 100 bases:

>100_bases
ACCAGTGGTTTTGACAAGTCTCCAGAACAGATGTCGCGCGAAAACAATGTAGCGGGCGGGATGGGCAAGATATCTTGCCC
GGCATCGCGGGGAGACACGC

Downstream 100 bases:

>100_bases
TCGGCTGGCCTGGCCGTGGCGTCGGCATCGCGCATCGCTGCGCGAACGCACCGACGCGGTGCCCGGAGCCGATGGCCGCG
ATGGCCGCGATGGCCGCGAT

Product: winged helix family two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MRILIAEDDATLADGLTRSLRQAGYAVDQASDGATADAALSAQTAQTYDLLILDVGLPRMSGLEVLKRLRSRGAMLPVLI
LTAADSVEERVKGLDLGADDYMAKPFALSELEARVRALVRRGTGGGATLVRHGPLAFDQVGRIAYIHDQVVELSAREIGL
LEILLARVGRLVSKEQLVDHLCGWGEEVSNNAIEVYIHRLRKKIEVEGIRIATVRGLGYCLERTATPTTTATAAHG

Sequences:

>Translated_236_residues
MRILIAEDDATLADGLTRSLRQAGYAVDQASDGATADAALSAQTAQTYDLLILDVGLPRMSGLEVLKRLRSRGAMLPVLI
LTAADSVEERVKGLDLGADDYMAKPFALSELEARVRALVRRGTGGGATLVRHGPLAFDQVGRIAYIHDQVVELSAREIGL
LEILLARVGRLVSKEQLVDHLCGWGEEVSNNAIEVYIHRLRKKIEVEGIRIATVRGLGYCLERTATPTTTATAAHG
>Mature_236_residues
MRILIAEDDATLADGLTRSLRQAGYAVDQASDGATADAALSAQTAQTYDLLILDVGLPRMSGLEVLKRLRSRGAMLPVLI
LTAADSVEERVKGLDLGADDYMAKPFALSELEARVRALVRRGTGGGATLVRHGPLAFDQVGRIAYIHDQVVELSAREIGL
LEILLARVGRLVSKEQLVDHLCGWGEEVSNNAIEVYIHRLRKKIEVEGIRIATVRGLGYCLERTATPTTTATAAHG

Specific function: Transcriptional activator of the tctI tricarboxylate transport system operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=43.8914027149321, Blast_Score=180, Evalue=6e-47,
Organism=Escherichia coli, GI1790552, Length=221, Percent_Identity=42.5339366515837, Blast_Score=164, Evalue=3e-42,
Organism=Escherichia coli, GI1787375, Length=224, Percent_Identity=38.8392857142857, Blast_Score=152, Evalue=1e-38,
Organism=Escherichia coli, GI1786784, Length=230, Percent_Identity=39.1304347826087, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=37.6681614349776, Blast_Score=137, Evalue=4e-34,
Organism=Escherichia coli, GI1786599, Length=224, Percent_Identity=34.8214285714286, Blast_Score=123, Evalue=1e-29,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=35.2678571428571, Blast_Score=121, Evalue=4e-29,
Organism=Escherichia coli, GI1789809, Length=230, Percent_Identity=31.7391304347826, Blast_Score=110, Evalue=8e-26,
Organism=Escherichia coli, GI1786911, Length=222, Percent_Identity=31.981981981982, Blast_Score=108, Evalue=4e-25,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=33.6244541484716, Blast_Score=103, Evalue=1e-23,
Organism=Escherichia coli, GI2367329, Length=231, Percent_Identity=32.034632034632, Blast_Score=96, Evalue=1e-21,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.4372294372294, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788713, Length=118, Percent_Identity=40.6779661016949, Blast_Score=77, Evalue=7e-16,
Organism=Escherichia coli, GI1787229, Length=232, Percent_Identity=29.7413793103448, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1790299, Length=108, Percent_Identity=35.1851851851852, Blast_Score=70, Evalue=9e-14,
Organism=Escherichia coli, GI145693140, Length=234, Percent_Identity=25.6410256410256, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790437, Length=111, Percent_Identity=37.8378378378378, Blast_Score=68, Evalue=4e-13,
Organism=Escherichia coli, GI1788550, Length=110, Percent_Identity=35.4545454545455, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788191, Length=124, Percent_Identity=33.0645161290323, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1787487, Length=104, Percent_Identity=35.5769230769231, Blast_Score=66, Evalue=2e-12,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR016032
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25438; Mature: 25438

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILIAEDDATLADGLTRSLRQAGYAVDQASDGATADAALSAQTAQTYDLLILDVGLPRM
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCC
SGLEVLKRLRSRGAMLPVLILTAADSVEERVKGLDLGADDYMAKPFALSELEARVRALVR
HHHHHHHHHHHCCCEEHHHEEHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHH
RGTGGGATLVRHGPLAFDQVGRIAYIHDQVVELSAREIGLLEILLARVGRLVSKEQLVDH
CCCCCCCEEEECCCCCHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCGWGEEVSNNAIEVYIHRLRKKIEVEGIRIATVRGLGYCLERTATPTTTATAAHG
HHCCCHHHCCCHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MRILIAEDDATLADGLTRSLRQAGYAVDQASDGATADAALSAQTAQTYDLLILDVGLPRM
CEEEEECCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCEEEEEEECCCCCC
SGLEVLKRLRSRGAMLPVLILTAADSVEERVKGLDLGADDYMAKPFALSELEARVRALVR
HHHHHHHHHHHCCCEEHHHEEHHHHHHHHHHHCCCCCCHHHHCCCHHHHHHHHHHHHHHH
RGTGGGATLVRHGPLAFDQVGRIAYIHDQVVELSAREIGLLEILLARVGRLVSKEQLVDH
CCCCCCCEEEECCCCCHHHHCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LCGWGEEVSNNAIEVYIHRLRKKIEVEGIRIATVRGLGYCLERTATPTTTATAAHG
HHCCCHHHCCCHHHHHHHHHHHHHHHCCEEEEEEHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2666399; 11083839; 11677609 [H]