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The map label for this gene is dctB [H]

Identifier: 187927295

GI number: 187927295

Start: 205388

End: 207406

Strand: Direct

Name: dctB [H]

Synonym: Rpic_0187

Alternate gene names: 187927295

Gene position: 205388-207406 (Clockwise)

Preceding gene: 187927294

Following gene: 187927296

Centisome position: 5.21

GC content: 65.53

Gene sequence:

>2019_bases
ATGCACCTCGTGAAGCACCTCGGCGACATGCCGACTGCGGGCACGGCGTTGGAAGGCACGGCAACACTCTCTGCCGCCGA
CCTCCAGCCGATGTCCGATCCCGATTTCTCCTTCACCAGCGCCTCCGGCTCGCGACGCGGCTTCTGGTGGCTGGTGGCGC
TCGGGCTCGTGGTGGTGATGGCCGTGGTGTGCGCGACCACCTTTGTGGTGGCGTGGAACCGGGGCCTCACGCAGGCCCAG
CAGGCCGCCGGAGGGCGGGTCGACCGCTATGCCGCCAACCTCAAGAGCACGCTCGATCGCTACGAATACCTGCCGGCCCT
GGTGGCGCTGCATCCGTTCATCCACGATCTGCTCGCCAATCCGACACCTGCCAACGTCGACCGCGCGAACCGCTATCTGC
GCGAAGTCAACGATCGCGCGCACGCCACTGCCACCTACGTGATCGCCCCCAGCGGCAAGGCGCTGGCAGCATCCAACTAC
AACCAGCCCGACAGCTTCGTCGGCGCCGAATATCTGTTCCGGCCGTATTTCCAGCAGGCAGCGGAAGGCCACGTCGGGCG
CTTCTACGGTATTGGCATTACGCGTGAAGAGCCCGGCTATTACATCTCCCAGCCGGTCATGCAGGATGGCCGCGTGATCG
GCGTGACGGTGGTCAAACTCAACCTCGAATGGTTCGGCCGCGCCAGCCACGACGCGTCGGAACCGGTGATGGTGGCGGAT
GAGAACGGTGTGATTTTCCTGTCGTCCGTGCCCGCGTGGCAGTACCGCACGGTGGAGCCGCTCACATCCAAGCTGCAGGC
GCAGTTGGAAGCGACGCGCCAGTATTACCGCAAGCAGATCACGCCTCTGCCGCTGCAGCCGGAGGCGCCGGCCTTTCTGC
GATTGACCGGGCGATTGCCCGAAGGTGCAGAACTGATCCGCGTTGGCGAGCGCACGAACGCCACGCGCTATCTGCAGGTT
TCGCGTGAACTGGTCGAGCCGGACTGGACGCTGATGTATCTCACGCCGGTGGAGCCCGTGATGAGTGCTGCGCGCAGCGC
CACCGTGGCGGCCGCATTTGCCTTTGCGTTCGCGTGCCTGCTGCTCTTCTACTGGCGTCAGCGGCGCCTGCGCATGATGG
AGATGCTGCGTAGCCGCCGCCTGCTCGAAGCCGCGTATGACCAGCTCGAGCGCCGTGTCGAAGACCGCACGGCCGACCTG
ATGGCCACCAATGAACAACTGCAGCACGAGATCGTCGACCGCACGCGTGCCGAGGCCGAACTGCGCGCCACGCAGGATGA
ACTCGTGCAGGCCAGCAAGCTTGCCGCGCTGGGCCAGATGGCCGCCGGCATCACGCACGAACTGAACCAGCCGCTGGCTG
CGCTGCGCACGTTCTCCGACAACACCCGTATCCTGCTCGAACGCGGCCAGCACGGCGCTGCCACCGATAACCTGCAGGCA
ATTGCCGACCTGACCGAGCGCATGGGCAAGATCACCGCACAGCTCAAGTTGTTTGCGGGACGCTCACGGCGCAAGGTGGT
GGATGTGCAGGTGCGCGTGGCGCTGGATCACACGCTCGCGCTGCTGCGCCCTCGCCTGGGCGACGTGTTGGTCGAACTGC
ACTGGCGCATCCCCGAGACAGAGGCCGTCGTTCGCGCAGATGAACTGAAGCTGGAGCAAGTGCTGATCAATCTGATTGGC
AACGCGCTCGATGCGATCAACGCCAATGAACCGGTACGCGCCGGCCGCATCGACATCACCATCGGCCCCACCGAGGGAGC
GCAGGCGCAATCGAATCAACTGACCATCGCCGTGCGCGACAACGGCCCTGGCATTCCGCCCGACGCCATGCCGCACCTGT
TCGAGCCGTTCTTCACCACCAAGGAGATCGGCCAGGGGCTCGGCCTTGGACTGGCGATTTCCACCAGCATCGCGCGCGAC
TTTGGCGGCTCGCTGTCGGCGGCCAACATGCCGGGCGGCGGGGCCCAATTTACGCTGACATTGGTACGCGCCGACGTCAC
CTCCGCGGCAACCACCTGA

Upstream 100 bases:

>100_bases
CGATCGGTTCTAGCCGGCGCCTGCGGGCGCCGGCGCCTGAAAGCGCAAAGCGTATGATTGCGGGGCCTGTCCTTCCAGAC
GGCCCCGCGTCTTTTTTGGG

Downstream 100 bases:

>100_bases
TCCGTTTTCCACACAGATACGAACCATGTCCGAAGGCTTGAACGTTCTCTTCATCGAAGACGACCCGCCTGTGCGCCAGG
CCACCGCGCAGAGCCTGGAA

Product: integral membrane sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 672; Mature: 672

Protein sequence:

>672_residues
MHLVKHLGDMPTAGTALEGTATLSAADLQPMSDPDFSFTSASGSRRGFWWLVALGLVVVMAVVCATTFVVAWNRGLTQAQ
QAAGGRVDRYAANLKSTLDRYEYLPALVALHPFIHDLLANPTPANVDRANRYLREVNDRAHATATYVIAPSGKALAASNY
NQPDSFVGAEYLFRPYFQQAAEGHVGRFYGIGITREEPGYYISQPVMQDGRVIGVTVVKLNLEWFGRASHDASEPVMVAD
ENGVIFLSSVPAWQYRTVEPLTSKLQAQLEATRQYYRKQITPLPLQPEAPAFLRLTGRLPEGAELIRVGERTNATRYLQV
SRELVEPDWTLMYLTPVEPVMSAARSATVAAAFAFAFACLLLFYWRQRRLRMMEMLRSRRLLEAAYDQLERRVEDRTADL
MATNEQLQHEIVDRTRAEAELRATQDELVQASKLAALGQMAAGITHELNQPLAALRTFSDNTRILLERGQHGAATDNLQA
IADLTERMGKITAQLKLFAGRSRRKVVDVQVRVALDHTLALLRPRLGDVLVELHWRIPETEAVVRADELKLEQVLINLIG
NALDAINANEPVRAGRIDITIGPTEGAQAQSNQLTIAVRDNGPGIPPDAMPHLFEPFFTTKEIGQGLGLGLAISTSIARD
FGGSLSAANMPGGGAQFTLTLVRADVTSAATT

Sequences:

>Translated_672_residues
MHLVKHLGDMPTAGTALEGTATLSAADLQPMSDPDFSFTSASGSRRGFWWLVALGLVVVMAVVCATTFVVAWNRGLTQAQ
QAAGGRVDRYAANLKSTLDRYEYLPALVALHPFIHDLLANPTPANVDRANRYLREVNDRAHATATYVIAPSGKALAASNY
NQPDSFVGAEYLFRPYFQQAAEGHVGRFYGIGITREEPGYYISQPVMQDGRVIGVTVVKLNLEWFGRASHDASEPVMVAD
ENGVIFLSSVPAWQYRTVEPLTSKLQAQLEATRQYYRKQITPLPLQPEAPAFLRLTGRLPEGAELIRVGERTNATRYLQV
SRELVEPDWTLMYLTPVEPVMSAARSATVAAAFAFAFACLLLFYWRQRRLRMMEMLRSRRLLEAAYDQLERRVEDRTADL
MATNEQLQHEIVDRTRAEAELRATQDELVQASKLAALGQMAAGITHELNQPLAALRTFSDNTRILLERGQHGAATDNLQA
IADLTERMGKITAQLKLFAGRSRRKVVDVQVRVALDHTLALLRPRLGDVLVELHWRIPETEAVVRADELKLEQVLINLIG
NALDAINANEPVRAGRIDITIGPTEGAQAQSNQLTIAVRDNGPGIPPDAMPHLFEPFFTTKEIGQGLGLGLAISTSIARD
FGGSLSAANMPGGGAQFTLTLVRADVTSAATT
>Mature_672_residues
MHLVKHLGDMPTAGTALEGTATLSAADLQPMSDPDFSFTSASGSRRGFWWLVALGLVVVMAVVCATTFVVAWNRGLTQAQ
QAAGGRVDRYAANLKSTLDRYEYLPALVALHPFIHDLLANPTPANVDRANRYLREVNDRAHATATYVIAPSGKALAASNY
NQPDSFVGAEYLFRPYFQQAAEGHVGRFYGIGITREEPGYYISQPVMQDGRVIGVTVVKLNLEWFGRASHDASEPVMVAD
ENGVIFLSSVPAWQYRTVEPLTSKLQAQLEATRQYYRKQITPLPLQPEAPAFLRLTGRLPEGAELIRVGERTNATRYLQV
SRELVEPDWTLMYLTPVEPVMSAARSATVAAAFAFAFACLLLFYWRQRRLRMMEMLRSRRLLEAAYDQLERRVEDRTADL
MATNEQLQHEIVDRTRAEAELRATQDELVQASKLAALGQMAAGITHELNQPLAALRTFSDNTRILLERGQHGAATDNLQA
IADLTERMGKITAQLKLFAGRSRRKVVDVQVRVALDHTLALLRPRLGDVLVELHWRIPETEAVVRADELKLEQVLINLIG
NALDAINANEPVRAGRIDITIGPTEGAQAQSNQLTIAVRDNGPGIPPDAMPHLFEPFFTTKEIGQGLGLGLAISTSIARD
FGGSLSAANMPGGGAQFTLTLVRADVTSAATT

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates dctD in response to environmental signals [H]

COG id: COG4191

COG function: function code T; Signal transduction histidine kinase regulating C4-dicarboxylate transport system

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=31.0924369747899, Blast_Score=110, Evalue=4e-25,
Organism=Escherichia coli, GI1788549, Length=273, Percent_Identity=30.03663003663, Blast_Score=109, Evalue=6e-25,
Organism=Escherichia coli, GI1789149, Length=289, Percent_Identity=27.3356401384083, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87081816, Length=305, Percent_Identity=28.1967213114754, Blast_Score=75, Evalue=1e-14,
Organism=Escherichia coli, GI145693157, Length=269, Percent_Identity=26.7657992565056, Blast_Score=73, Evalue=8e-14,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=27.5109170305677, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI48994928, Length=265, Percent_Identity=27.1698113207547, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1790861, Length=241, Percent_Identity=29.8755186721992, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR017055
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 73860; Mature: 73860

Theoretical pI: Translated: 6.72; Mature: 6.72

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHLVKHLGDMPTAGTALEGTATLSAADLQPMSDPDFSFTSASGSRRGFWWLVALGLVVVM
CCHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHH
AVVCATTFVVAWNRGLTQAQQAAGGRVDRYAANLKSTLDRYEYLPALVALHPFIHDLLAN
HHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PTPANVDRANRYLREVNDRAHATATYVIAPSGKALAASNYNQPDSFVGAEYLFRPYFQQA
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHH
AEGHVGRFYGIGITREEPGYYISQPVMQDGRVIGVTVVKLNLEWFGRASHDASEPVMVAD
HCCCCCEEEEEEEEECCCCCEECCCHHCCCEEEEEEEEEEEHHHCCCCCCCCCCCEEEEC
ENGVIFLSSVPAWQYRTVEPLTSKLQAQLEATRQYYRKQITPLPLQPEAPAFLRLTGRLP
CCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCC
EGAELIRVGERTNATRYLQVSRELVEPDWTLMYLTPVEPVMSAARSATVAAAFAFAFACL
CCCHHEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LLFYWRQRRLRMMEMLRSRRLLEAAYDQLERRVEDRTADLMATNEQLQHEIVDRTRAEAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRATQDELVQASKLAALGQMAAGITHELNQPLAALRTFSDNTRILLERGQHGAATDNLQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCCCHHHHH
IADLTERMGKITAQLKLFAGRSRRKVVDVQVRVALDHTLALLRPRLGDVLVELHWRIPET
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCH
EAVVRADELKLEQVLINLIGNALDAINANEPVRAGRIDITIGPTEGAQAQSNQLTIAVRD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEC
NGPGIPPDAMPHLFEPFFTTKEIGQGLGLGLAISTSIARDFGGSLSAANMPGGGAQFTLT
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
LVRADVTSAATT
EEEEHHHHCCCC
>Mature Secondary Structure
MHLVKHLGDMPTAGTALEGTATLSAADLQPMSDPDFSFTSASGSRRGFWWLVALGLVVVM
CCHHHHCCCCCCCCCCCCCCCEEECCCCCCCCCCCCCEECCCCCCCCHHHHHHHHHHHHH
AVVCATTFVVAWNRGLTQAQQAAGGRVDRYAANLKSTLDRYEYLPALVALHPFIHDLLAN
HHHHHHHHHHHHCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PTPANVDRANRYLREVNDRAHATATYVIAPSGKALAASNYNQPDSFVGAEYLFRPYFQQA
CCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEECCCCCCCCHHHHHHHHHHHHHHHH
AEGHVGRFYGIGITREEPGYYISQPVMQDGRVIGVTVVKLNLEWFGRASHDASEPVMVAD
HCCCCCEEEEEEEEECCCCCEECCCHHCCCEEEEEEEEEEEHHHCCCCCCCCCCCEEEEC
ENGVIFLSSVPAWQYRTVEPLTSKLQAQLEATRQYYRKQITPLPLQPEAPAFLRLTGRLP
CCCEEEEECCCCCCCEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECCCC
EGAELIRVGERTNATRYLQVSRELVEPDWTLMYLTPVEPVMSAARSATVAAAFAFAFACL
CCCHHEEECCCCCCHHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHH
LLFYWRQRRLRMMEMLRSRRLLEAAYDQLERRVEDRTADLMATNEQLQHEIVDRTRAEAE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LRATQDELVQASKLAALGQMAAGITHELNQPLAALRTFSDNTRILLERGQHGAATDNLQA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCEEEEECCCCCCCCHHHHH
IADLTERMGKITAQLKLFAGRSRRKVVDVQVRVALDHTLALLRPRLGDVLVELHWRIPET
HHHHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEHHHHHHHHHHHHHHHHHHHCCCCCCH
EAVVRADELKLEQVLINLIGNALDAINANEPVRAGRIDITIGPTEGAQAQSNQLTIAVRD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCCCCCCEEEEEEEC
NGPGIPPDAMPHLFEPFFTTKEIGQGLGLGLAISTSIARDFGGSLSAANMPGGGAQFTLT
CCCCCCCCCCHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEE
LVRADVTSAATT
EEEEHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3671068 [H]