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The map label for this gene is dctD [H]

Identifier: 187927296

GI number: 187927296

Start: 207432

End: 208748

Strand: Direct

Name: dctD [H]

Synonym: Rpic_0188

Alternate gene names: 187927296

Gene position: 207432-208748 (Clockwise)

Preceding gene: 187927295

Following gene: 187927300

Centisome position: 5.26

GC content: 66.21

Gene sequence:

>1317_bases
ATGTCCGAAGGCTTGAACGTTCTCTTCATCGAAGACGACCCGCCTGTGCGCCAGGCCACCGCGCAGAGCCTGGAACTGGC
CGGCTTCAATGTGCAGGCGTTCGGCAGCGCCGAAGAAGCCGTCGGCAAGATCGACGCGAACTTTCCCGGCGTGGTCGTGA
GCGACCTGCGCCTGCCGGGCGCGAGCGGCCTGGACGTGCTCACGCACTGCCAGTCGTTTGGCACGGGCATTCCCGTGGTG
CTTGTCACCGGCCATGGCGACATCACGATGGCCGTGCAGGCCATGCGCGAAGGCGCGTTCGACTTCATCGAGAAGCCGTT
TCCCGCCGAACGCTTGACCGAGACGGTGCGTCGCGCCGTCGAACGCCGCGCGCTGGAGTTGGAAAACCGCGCACTGCGTC
GTGAACTGGCCGGCCCGGCGGCTGGCACGCGCATCATCGGGCGCTCACCAGCGATGGCCGCCGTACGCGCGCTGATCGAG
AACGTCGCGACCACCGATGCGCCGGTGCTCATCAACGGCGAGACCGGCACGGGCAAGGAACTCGTCGCGCGCAGTCTGCA
CATGCTCTCGCCGCGTCACGACAAGCCGTTCATCGCGCTGAACTGCGGCGCCGTGCCTGAACAGATTTTCGAGAGCGAGA
TGTTCGGCTACGAGGCCGGTGCCTTCACCGGTGCGGGCAAGCGGCGCATCGGCAAGCTTGAGCACGCATCGGGCGGCACG
CTGTTTCTCGACGAAATCGAGAGCATGCCGATCGCGCTGCAGGTCAAGCTGCTGCGCGTGTTGCAGGAGGGCGCGCTGGA
GCGGCTGGGCTCGAATGCTTCGGTGCGCATCGACGTGCGCATCGTTGCGGCCGCCAAGGGCGATATGGAAGCGCTGATCG
AGGCGGGCGGTTTCCGGCGCGATCTGTACTACCGCCTGAATGTCGTCGTCATCGACCTGCCACCGCTGCGCGAACGCCGC
GAAGACATCATCCCGCTGTTCGAACATTTCCTGCTCGAAGCCGCTGTGCGCTATCAGCGTCCGCTGCCGATGCTGGCCGA
GCGTCAGCGCCACGAGCTGATGCAATCGAACTGGCCCGGCAACGTGCGCGAGCTGCGTAATGCGGCCGACCGTCTTGTGC
TTGGCGTCGGCCGCATGCCGGTCGTGCCGGATGCTTCGGAAGACGGCATGCCGCTCAAGGAGCGCGTCGAGCGCTACGAG
CGCACGGTGATTGCCGAAACACTGGCGCGCACGGGCGGCTCGGTCCACCAGGCGGCGGACATTCTGCAGGTCGGCCGTGC
GACGCTGTATGACAAGATCAAGCGGTACGGCCTTTGA

Upstream 100 bases:

>100_bases
AACATGCCGGGCGGCGGGGCCCAATTTACGCTGACATTGGTACGCGCCGACGTCACCTCCGCGGCAACCACCTGATCCGT
TTTCCACACAGATACGAACC

Downstream 100 bases:

>100_bases
CTTGGCACGCCCACACGCGACCACGCGCGGCACAAACCGGGCGTTGTCTTTTCGCGCTCAACCCGGAATCGGATGCGCAT
CCGCCACCGGATATCCACGG

Product: Fis family two component sigma-54 specific transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 438; Mature: 437

Protein sequence:

>438_residues
MSEGLNVLFIEDDPPVRQATAQSLELAGFNVQAFGSAEEAVGKIDANFPGVVVSDLRLPGASGLDVLTHCQSFGTGIPVV
LVTGHGDITMAVQAMREGAFDFIEKPFPAERLTETVRRAVERRALELENRALRRELAGPAAGTRIIGRSPAMAAVRALIE
NVATTDAPVLINGETGTGKELVARSLHMLSPRHDKPFIALNCGAVPEQIFESEMFGYEAGAFTGAGKRRIGKLEHASGGT
LFLDEIESMPIALQVKLLRVLQEGALERLGSNASVRIDVRIVAAAKGDMEALIEAGGFRRDLYYRLNVVVIDLPPLRERR
EDIIPLFEHFLLEAAVRYQRPLPMLAERQRHELMQSNWPGNVRELRNAADRLVLGVGRMPVVPDASEDGMPLKERVERYE
RTVIAETLARTGGSVHQAADILQVGRATLYDKIKRYGL

Sequences:

>Translated_438_residues
MSEGLNVLFIEDDPPVRQATAQSLELAGFNVQAFGSAEEAVGKIDANFPGVVVSDLRLPGASGLDVLTHCQSFGTGIPVV
LVTGHGDITMAVQAMREGAFDFIEKPFPAERLTETVRRAVERRALELENRALRRELAGPAAGTRIIGRSPAMAAVRALIE
NVATTDAPVLINGETGTGKELVARSLHMLSPRHDKPFIALNCGAVPEQIFESEMFGYEAGAFTGAGKRRIGKLEHASGGT
LFLDEIESMPIALQVKLLRVLQEGALERLGSNASVRIDVRIVAAAKGDMEALIEAGGFRRDLYYRLNVVVIDLPPLRERR
EDIIPLFEHFLLEAAVRYQRPLPMLAERQRHELMQSNWPGNVRELRNAADRLVLGVGRMPVVPDASEDGMPLKERVERYE
RTVIAETLARTGGSVHQAADILQVGRATLYDKIKRYGL
>Mature_437_residues
SEGLNVLFIEDDPPVRQATAQSLELAGFNVQAFGSAEEAVGKIDANFPGVVVSDLRLPGASGLDVLTHCQSFGTGIPVVL
VTGHGDITMAVQAMREGAFDFIEKPFPAERLTETVRRAVERRALELENRALRRELAGPAAGTRIIGRSPAMAAVRALIEN
VATTDAPVLINGETGTGKELVARSLHMLSPRHDKPFIALNCGAVPEQIFESEMFGYEAGAFTGAGKRRIGKLEHASGGTL
FLDEIESMPIALQVKLLRVLQEGALERLGSNASVRIDVRIVAAAKGDMEALIEAGGFRRDLYYRLNVVVIDLPPLRERRE
DIIPLFEHFLLEAAVRYQRPLPMLAERQRHELMQSNWPGNVRELRNAADRLVLGVGRMPVVPDASEDGMPLKERVERYER
TVIAETLARTGGSVHQAADILQVGRATLYDKIKRYGL

Specific function: Member of the two-component regulatory system dctB/dctD involved in the transport of C4-dicarboxylates. When activated by dctB acts in conjunction with sigma-54 to activate the transcription of dctA [H]

COG id: COG2204

COG function: function code T; Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 sigma-54 factor interaction domain [H]

Homologues:

Organism=Escherichia coli, GI1788550, Length=450, Percent_Identity=38.6666666666667, Blast_Score=320, Evalue=1e-88,
Organism=Escherichia coli, GI1790299, Length=473, Percent_Identity=38.6892177589852, Blast_Score=307, Evalue=9e-85,
Organism=Escherichia coli, GI1790437, Length=448, Percent_Identity=37.9464285714286, Blast_Score=297, Evalue=1e-81,
Organism=Escherichia coli, GI1788905, Length=442, Percent_Identity=38.9140271493213, Blast_Score=286, Evalue=2e-78,
Organism=Escherichia coli, GI87082117, Length=341, Percent_Identity=40.7624633431085, Blast_Score=241, Evalue=6e-65,
Organism=Escherichia coli, GI1789087, Length=324, Percent_Identity=44.4444444444444, Blast_Score=230, Evalue=2e-61,
Organism=Escherichia coli, GI1789233, Length=320, Percent_Identity=40.9375, Blast_Score=228, Evalue=8e-61,
Organism=Escherichia coli, GI87082152, Length=319, Percent_Identity=41.3793103448276, Blast_Score=222, Evalue=4e-59,
Organism=Escherichia coli, GI87081872, Length=234, Percent_Identity=47.008547008547, Blast_Score=218, Evalue=6e-58,
Organism=Escherichia coli, GI1786524, Length=312, Percent_Identity=41.9871794871795, Blast_Score=216, Evalue=3e-57,
Organism=Escherichia coli, GI1787583, Length=314, Percent_Identity=38.8535031847134, Blast_Score=208, Evalue=6e-55,
Organism=Escherichia coli, GI87081858, Length=290, Percent_Identity=32.4137931034483, Blast_Score=143, Evalue=2e-35,
Organism=Escherichia coli, GI1789828, Length=253, Percent_Identity=34.7826086956522, Blast_Score=131, Evalue=9e-32,
Organism=Escherichia coli, GI1786599, Length=119, Percent_Identity=32.7731092436975, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1789809, Length=127, Percent_Identity=29.9212598425197, Blast_Score=65, Evalue=1e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR011006
- InterPro:   IPR009057
- InterPro:   IPR002197
- InterPro:   IPR002078
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02954 HTH_8; PF00072 Response_reg; PF00158 Sigma54_activat [H]

EC number: NA

Molecular weight: Translated: 47937; Mature: 47806

Theoretical pI: Translated: 6.15; Mature: 6.15

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00675 SIGMA54_INTERACT_1 ; PS00676 SIGMA54_INTERACT_2 ; PS00688 SIGMA54_INTERACT_3 ; PS50045 SIGMA54_INTERACT_4

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEGLNVLFIEDDPPVRQATAQSLELAGFNVQAFGSAEEAVGKIDANFPGVVVSDLRLPG
CCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCCCEEEECCCCCC
ASGLDVLTHCQSFGTGIPVVLVTGHGDITMAVQAMREGAFDFIEKPFPAERLTETVRRAV
CCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ERRALELENRALRRELAGPAAGTRIIGRSPAMAAVRALIENVATTDAPVLINGETGTGKE
HHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
LVARSLHMLSPRHDKPFIALNCGAVPEQIFESEMFGYEAGAFTGAGKRRIGKLEHASGGT
HHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCE
LFLDEIESMPIALQVKLLRVLQEGALERLGSNASVRIDVRIVAAAKGDMEALIEAGGFRR
EEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHCCCCCE
DLYYRLNVVVIDLPPLRERREDIIPLFEHFLLEAAVRYQRPLPMLAERQRHELMQSNWPG
EEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
NVRELRNAADRLVLGVGRMPVVPDASEDGMPLKERVERYERTVIAETLARTGGSVHQAAD
CHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILQVGRATLYDKIKRYGL
HHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SEGLNVLFIEDDPPVRQATAQSLELAGFNVQAFGSAEEAVGKIDANFPGVVVSDLRLPG
CCCCEEEEECCCCCHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCCCEEEECCCCCC
ASGLDVLTHCQSFGTGIPVVLVTGHGDITMAVQAMREGAFDFIEKPFPAERLTETVRRAV
CCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
ERRALELENRALRRELAGPAAGTRIIGRSPAMAAVRALIENVATTDAPVLINGETGTGKE
HHHHHHHHHHHHHHHHCCCCCCCEEECCCHHHHHHHHHHHHHHCCCCCEEEECCCCCCHH
LVARSLHMLSPRHDKPFIALNCGAVPEQIFESEMFGYEAGAFTGAGKRRIGKLEHASGGT
HHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCE
LFLDEIESMPIALQVKLLRVLQEGALERLGSNASVRIDVRIVAAAKGDMEALIEAGGFRR
EEEEHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEECCCCHHHHHHCCCCCE
DLYYRLNVVVIDLPPLRERREDIIPLFEHFLLEAAVRYQRPLPMLAERQRHELMQSNWPG
EEEEEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
NVRELRNAADRLVLGVGRMPVVPDASEDGMPLKERVERYERTVIAETLARTGGSVHQAAD
CHHHHHHHHHHHEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ILQVGRATLYDKIKRYGL
HHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2134335; 2793824; 11481431 [H]