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The map label for this gene is yceE [C]

Identifier: 187927281

GI number: 187927281

Start: 190508

End: 191752

Strand: Reverse

Name: yceE [C]

Synonym: Rpic_0173

Alternate gene names: 187927281

Gene position: 191752-190508 (Counterclockwise)

Preceding gene: 187927282

Following gene: 187927275

Centisome position: 4.86

GC content: 68.59

Gene sequence:

>1245_bases
ATGAGCCCCGCAACGCCCGTGGACGCGTGGCGCGAGGCCATTCGGTGGCTCCTCGTCATCCAGGCCCTTTCAATGGGCGC
GATGGAAATGACAGGGCCGTTCTGGCCACTGTTCCTGCGCGAGCTGTCGCCGGTGCCGCATGTGCCGTTCGCGTGGGTGG
CGAGCGCAGCGTACTTCGCGCCGATGGCCGCCACGCTTGTCACCGCGCCCTGGTGGGGCCGCCTGGCTGATCGCGTCGGG
CCCAAGCCGATGATCTTGCGAGCGCTCATCGCGCTGGCAGCGTCGCAGCTGTGGTCGGTCCATGCGGACTCGGCGGCCAG
CGTGCTGCTGGCGCGCACCGTGCAAGGCGGGCTGGCCGGCTTTCTGGCAGCCGCACAGATCTATGCGATGCGCGTGGCAC
CTGCCGACATGCGCCGGCGCGTCTTCGCCGATCTGCAGACCGTCACGGCGTGCGGCAGCTTCATGGCTCCGCCGGTCGGC
GCATGGCTCGTCTCGTGGATGGGCTTCCGGATGGCCAACACGGCGGGCGCGGTGGTGATTCTGGCGTGCGTTCCGCTGGC
GATGTTCTGCTTGCCGGGCATCGGCCCCGCCCCGCGCAGCGCGTCGAAATCGACCTCCGACATGCTGCAATCACGGCACG
CGCCCTTGAGCGGCCTGGTGATCGGCTTGTTGCTCGGGACGGTAGCTGTGCAGGCGGCGCGCGTCATGCCCCAAGGCTTT
CTCGCGCCGTACATCACCGAGACACTGCATGGCTCGGTGATACTGGCAGGTCTCGCCTACAGCGCGACGGCGGCAACACT
GGCGCTGTCTGCGCGCTGGTGGGCAAAGCGGTTTGCCGGACTGCCCGTGCATGTCACGCTGGGGCGCGTGTGCGCATTGA
CCGCGGTATGCGGCGTCACCGCGCTCTGGCAAGGCCTTGCGCAAGGGGAAGTCGGCTTCATTGCCGCACGTTTGGCCTGG
GGCCTGTGCCTTGGCGGCCTGCTGCCGGTCCTCAACAGCCTGGTCGCTGAGACAAGCCCGGAAGATCGTCAAGGTTTTGC
GTTGGGATTGTGTAGTAGCGCAGCCAAGGGCGGTGCCCTCGTCGGCTTGGGCGTGGCCGCCTGGTCGACAGGCGTGTTCG
GGTGGCGCGCGGGTTTTGTCGCCATGGCGGCGATGTACCTGGCGGCGCTGGCAGCACTGATTGCGGTGCGGCGCGCTGCC
TCACCGCATCCCGCATCTGCTGCGGCGGGCACTCAACGCGCGTGA

Upstream 100 bases:

>100_bases
CGCCATGGTCGTTCAAGACGTTCGTTCGCATGCGCCTGCGCGACCAGTCCGACGACATGCACGCCGCGCTGCCTAACCCG
CTGGCCGACGCGGTTCGGAC

Downstream 100 bases:

>100_bases
CGTCCGGCGCGCCGCTGCAGCTGCGTCTGCTCGGCGCGCCAGGCGAGATAGCCGAGGCCCAGAAACGGCCACAGCCAGCC
GATCCATTGCGACAGGCTGT

Product: major facilitator superfamily protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 414; Mature: 413

Protein sequence:

>414_residues
MSPATPVDAWREAIRWLLVIQALSMGAMEMTGPFWPLFLRELSPVPHVPFAWVASAAYFAPMAATLVTAPWWGRLADRVG
PKPMILRALIALAASQLWSVHADSAASVLLARTVQGGLAGFLAAAQIYAMRVAPADMRRRVFADLQTVTACGSFMAPPVG
AWLVSWMGFRMANTAGAVVILACVPLAMFCLPGIGPAPRSASKSTSDMLQSRHAPLSGLVIGLLLGTVAVQAARVMPQGF
LAPYITETLHGSVILAGLAYSATAATLALSARWWAKRFAGLPVHVTLGRVCALTAVCGVTALWQGLAQGEVGFIAARLAW
GLCLGGLLPVLNSLVAETSPEDRQGFALGLCSSAAKGGALVGLGVAAWSTGVFGWRAGFVAMAAMYLAALAALIAVRRAA
SPHPASAAAGTQRA

Sequences:

>Translated_414_residues
MSPATPVDAWREAIRWLLVIQALSMGAMEMTGPFWPLFLRELSPVPHVPFAWVASAAYFAPMAATLVTAPWWGRLADRVG
PKPMILRALIALAASQLWSVHADSAASVLLARTVQGGLAGFLAAAQIYAMRVAPADMRRRVFADLQTVTACGSFMAPPVG
AWLVSWMGFRMANTAGAVVILACVPLAMFCLPGIGPAPRSASKSTSDMLQSRHAPLSGLVIGLLLGTVAVQAARVMPQGF
LAPYITETLHGSVILAGLAYSATAATLALSARWWAKRFAGLPVHVTLGRVCALTAVCGVTALWQGLAQGEVGFIAARLAW
GLCLGGLLPVLNSLVAETSPEDRQGFALGLCSSAAKGGALVGLGVAAWSTGVFGWRAGFVAMAAMYLAALAALIAVRRAA
SPHPASAAAGTQRA
>Mature_413_residues
SPATPVDAWREAIRWLLVIQALSMGAMEMTGPFWPLFLRELSPVPHVPFAWVASAAYFAPMAATLVTAPWWGRLADRVGP
KPMILRALIALAASQLWSVHADSAASVLLARTVQGGLAGFLAAAQIYAMRVAPADMRRRVFADLQTVTACGSFMAPPVGA
WLVSWMGFRMANTAGAVVILACVPLAMFCLPGIGPAPRSASKSTSDMLQSRHAPLSGLVIGLLLGTVAVQAARVMPQGFL
APYITETLHGSVILAGLAYSATAATLALSARWWAKRFAGLPVHVTLGRVCALTAVCGVTALWQGLAQGEVGFIAARLAWG
LCLGGLLPVLNSLVAETSPEDRQGFALGLCSSAAKGGALVGLGVAAWSTGVFGWRAGFVAMAAMYLAALAALIAVRRAAS
PHPASAAAGTQRA

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42976; Mature: 42845

Theoretical pI: Translated: 10.68; Mature: 10.68

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPATPVDAWREAIRWLLVIQALSMGAMEMTGPFWPLFLRELSPVPHVPFAWVASAAYFA
CCCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHH
PMAATLVTAPWWGRLADRVGPKPMILRALIALAASQLWSVHADSAASVLLARTVQGGLAG
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLAAAQIYAMRVAPADMRRRVFADLQTVTACGSFMAPPVGAWLVSWMGFRMANTAGAVVI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHH
LACVPLAMFCLPGIGPAPRSASKSTSDMLQSRHAPLSGLVIGLLLGTVAVQAARVMPQGF
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
LAPYITETLHGSVILAGLAYSATAATLALSARWWAKRFAGLPVHVTLGRVCALTAVCGVT
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
ALWQGLAQGEVGFIAARLAWGLCLGGLLPVLNSLVAETSPEDRQGFALGLCSSAAKGGAL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCE
VGLGVAAWSTGVFGWRAGFVAMAAMYLAALAALIAVRRAASPHPASAAAGTQRA
EEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPATPVDAWREAIRWLLVIQALSMGAMEMTGPFWPLFLRELSPVPHVPFAWVASAAYFA
CCCCHHHHHHHHHHHHHHHHHHHCCCHHHCCCHHHHHHHHCCCCCCCCHHHHHHHHHHH
PMAATLVTAPWWGRLADRVGPKPMILRALIALAASQLWSVHADSAASVLLARTVQGGLAG
HHHHHHHCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
FLAAAQIYAMRVAPADMRRRVFADLQTVTACGSFMAPPVGAWLVSWMGFRMANTAGAVVI
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHH
LACVPLAMFCLPGIGPAPRSASKSTSDMLQSRHAPLSGLVIGLLLGTVAVQAARVMPQGF
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCHH
LAPYITETLHGSVILAGLAYSATAATLALSARWWAKRFAGLPVHVTLGRVCALTAVCGVT
HHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHH
ALWQGLAQGEVGFIAARLAWGLCLGGLLPVLNSLVAETSPEDRQGFALGLCSSAAKGGAL
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCE
VGLGVAAWSTGVFGWRAGFVAMAAMYLAALAALIAVRRAASPHPASAAAGTQRA
EEHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9163424 [H]