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The map label for this gene is rfbC [H]

Identifier: 187935603

GI number: 187935603

Start: 3407218

End: 3407757

Strand: Reverse

Name: rfbC [H]

Synonym: CLL_A3252

Alternate gene names: 187935603

Gene position: 3407757-3407218 (Counterclockwise)

Preceding gene: 187935321

Following gene: 187934855

Centisome position: 89.67

GC content: 29.07

Gene sequence:

>540_bases
ATGAATTTAATTAAAACTAAATTAGATGGTGTTTATATAGTAGAACCACAAGTTTTTGGAGATGAAAGAGGCTGGTTTAT
GGAAACTTACTCAAAAATTAAAACACCAGAAATAGCTTGTGATTTTATACAAGATAATCAATCATATTCAAAAGAAAAGG
GAATTCTTAGAGGAATTCATTTTCAAAATGGAAAACATGCACAAGCAAAACTAGTAAGATGTGTAAGGGGAGCTGTATTA
GATGTAGCTGTGGATCTAAGAAAAAATTCGCCTACATATAAACAATGGGTAGCTGTAGAGCTTTCAGCAGAAAATAAAAA
GCAATTATTTATACCAAGAGGTTTTGGACATGGATTTGTAACATTAACTGATGATGTTGAATTTGTATATAAAACAGATA
ATTATTATAATCACGAAAGTGATAGAAGCATTAGATTTAATGATCCAGAAATAGGAGTTGAATGGGGAATAAAAAATCCT
ATTCTTTCAGAAAAAGATAAAAAAGCACCACTTTTAAAGGATAGTGATTGTATTTTTTAA

Upstream 100 bases:

>100_bases
AAAGTCCATATGGGAAGCACTTATATAATGTAGCAAATAATAAAGTTATTTATTAAATGACAATAATCAATTGTCTATTG
CAAGAGAGGTGCGTATAACA

Downstream 100 bases:

>100_bases
TGATAGTCTAAATTTTTAAGTAATATCTATGCATATTACTAAGATTAAGTTCAGACAAATAGAATTTGTTAAATTTATTA
TAGAGTTTTAGATAAATGGT

Product: dTDP-4-dehydrorhamnose 3,5-epimerase

Products: NA

Alternate protein names: Thymidine diphospho-4-keto-rhamnose 3,5-epimerase; dTDP-4-keto-6-deoxyglucose 3,5-epimerase; dTDP-6-deoxy-D-xylo-4-hexulose 3,5-epimerase; dTDP-L-rhamnose synthase [H]

Number of amino acids: Translated: 179; Mature: 179

Protein sequence:

>179_residues
MNLIKTKLDGVYIVEPQVFGDERGWFMETYSKIKTPEIACDFIQDNQSYSKEKGILRGIHFQNGKHAQAKLVRCVRGAVL
DVAVDLRKNSPTYKQWVAVELSAENKKQLFIPRGFGHGFVTLTDDVEFVYKTDNYYNHESDRSIRFNDPEIGVEWGIKNP
ILSEKDKKAPLLKDSDCIF

Sequences:

>Translated_179_residues
MNLIKTKLDGVYIVEPQVFGDERGWFMETYSKIKTPEIACDFIQDNQSYSKEKGILRGIHFQNGKHAQAKLVRCVRGAVL
DVAVDLRKNSPTYKQWVAVELSAENKKQLFIPRGFGHGFVTLTDDVEFVYKTDNYYNHESDRSIRFNDPEIGVEWGIKNP
ILSEKDKKAPLLKDSDCIF
>Mature_179_residues
MNLIKTKLDGVYIVEPQVFGDERGWFMETYSKIKTPEIACDFIQDNQSYSKEKGILRGIHFQNGKHAQAKLVRCVRGAVL
DVAVDLRKNSPTYKQWVAVELSAENKKQLFIPRGFGHGFVTLTDDVEFVYKTDNYYNHESDRSIRFNDPEIGVEWGIKNP
ILSEKDKKAPLLKDSDCIF

Specific function: Catalyzes the epimerization of the C3' and C5'positions of dTDP-6-deoxy-D-xylo-4-hexulose, forming dTDP-6-deoxy-L-lyxo-4- hexulose [H]

COG id: COG1898

COG function: function code M; dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dTDP-4-dehydrorhamnose 3,5-epimerase family [H]

Homologues:

Organism=Escherichia coli, GI1788350, Length=172, Percent_Identity=51.7441860465116, Blast_Score=177, Evalue=3e-46,
Organism=Caenorhabditis elegans, GI17550412, Length=170, Percent_Identity=39.4117647058824, Blast_Score=112, Evalue=9e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011051
- InterPro:   IPR000888
- InterPro:   IPR014710
- ProDom:   PD001462 [H]

Pfam domain/function: PF00908 dTDP_sugar_isom [H]

EC number: =5.1.3.13 [H]

Molecular weight: Translated: 20594; Mature: 20594

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLIKTKLDGVYIVEPQVFGDERGWFMETYSKIKTPEIACDFIQDNQSYSKEKGILRGIH
CCCCEECCCCEEEECCEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHCCCEEEEE
FQNGKHAQAKLVRCVRGAVLDVAVDLRKNSPTYKQWVAVELSAENKKQLFIPRGFGHGFV
CCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEEEECCCCCEEEEEECCCCCEEE
TLTDDVEFVYKTDNYYNHESDRSIRFNDPEIGVEWGIKNPILSEKDKKAPLLKDSDCIF
EEECCEEEEEECCCEECCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNLIKTKLDGVYIVEPQVFGDERGWFMETYSKIKTPEIACDFIQDNQSYSKEKGILRGIH
CCCCEECCCCEEEECCEEECCCCCHHHHHHHHCCCCCEEEEEECCCCCCCHHCCCEEEEE
FQNGKHAQAKLVRCVRGAVLDVAVDLRKNSPTYKQWVAVELSAENKKQLFIPRGFGHGFV
CCCCCHHHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEEEECCCCCEEEEEECCCCCEEE
TLTDDVEFVYKTDNYYNHESDRSIRFNDPEIGVEWGIKNPILSEKDKKAPLLKDSDCIF
EEECCEEEEEECCCEECCCCCCEEEECCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1710759; 11677609; 10802738 [H]