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The map label for this gene is yycG [H]

Identifier: 187934523

GI number: 187934523

Start: 1963124

End: 1964767

Strand: Reverse

Name: yycG [H]

Synonym: CLL_A1864

Alternate gene names: 187934523

Gene position: 1964767-1963124 (Counterclockwise)

Preceding gene: 187935541

Following gene: 187932636

Centisome position: 51.7

GC content: 22.69

Gene sequence:

>1644_bases
GTGCTGACGGAAGGGAAAAAGGGGATTAACAAAAAGTTAATATTGCTTATAATAACAAATGTAATTAGCTTTTATATTAT
ATTTAGATTGAATATTTTTATGGCTAATAATGTAGACTTGGCTGAATTAACTCTTATTAAGGATATAAAAGGTATAAATT
ATATAATAGGATTTATATCAGTGTTTTGTTGTTTTTTATATTATTATTTATACGAAGAAAATTATTTTTTTATGTTTTCA
CTAATCTATCTATCTATCTATTCTGAATTTTTAATAGTTGATTTTCTAACAAAGCATATAAATATAAGTGCTCTTATGCA
TTCTAACTCATCATTTGTAGGTTTTGCATCAATATTTAGAACGCTATTATTATATTTAACTATATTCAATCAAAATAAAG
TAACCAAAGGTATTTGTAAAAATAGATTTGCTACAGTAATATTTGTTTTGATTTCTAATGTATTATTTATATTAATGGAT
TTAAATATAATGAAGTACTATTCACATGTAATTAATATAGATGTTCTTATGATTATTAAGAATATAATAAATTTAGCGAC
GTACTTATTAATATTAGAAGTGTGTATAAAATATTTTAAAGAAAAAGAATTTAATTATTTTATAACTTTTGCTAGTTTAA
GTGTTATGTTTTTGAGTAGAATTTTACTAGTTAAAAGTTTATATAATGATCAAAAGATGATGTACATATTAAATCGCTGT
CTATTGGCATTAGGTTTTTTTATAATAATAATCAGTGTATTTATAGAAATAATAACTAAGTCTAAAGAAAATAAAGAGTT
AAGTTATGAAGTGGTTAATCAAAAAAATGAAATGTATAAATTGAAGGAAGAAGAGGAAATGAGGAGTCAATTTTTTGCAA
ACATATCTCATGAACTTAGAACACCTCTTAATATAATTATTTCATCTTTTCAACTTCTAAGAATGTACAATTATAATGAA
GAAGAATTTTTAAAATACTACAATAAATATGAAAACACAATTTCACAAAATTGTTCTAGGATGTTAAGACTTATTAATAA
TATTATTGATGTTACTAAGTTTGATGCTGGATGTTTCAAAATGAATTTTGTTAATTGTGAAATTATTAGTTTGGTTGAAA
ATATAACTTTATCAATAGCAGAATATGAGAAAGCTAGAAAAAGGAATATAATTTTTGATACAGATTGTGAGTTTCTTGAA
ATAAAGTGTGATCCAGAAAATATGGAAAGAGCAATTTTAAATCTTCTTTCTAATGCTATTAAATTTACAAGTGATAATGG
AAATATATTTGTAAGTATTGAAAGTCAAAATAATGATGAGTGTTTAAGCATAACTATAAAAGATGATGGAATAGGAATTC
CAAAAGATTTTAGAAAAAGCGTTTTTGAAAGATTTGTACAAGTTGATAAGTCTTTTAGAAGAAATGTAGAGGGAAGTGGA
ATAGGCTTATCTTTAGTTAAATATATAGTAAATTCTCATAATGGAGAGATTAATCTAAAAGATAATGAAGAAAAAGGTTG
CGAATTTATAATTAATTTACCTAATGTAAAGATAGAGGACGAGTTAGATGATATTGAATTCAATTTGCATAAAAAAGATG
AAATTGATAGTAAAATACTTATTGAACTTTCAGATATTAAATAA

Upstream 100 bases:

>100_bases
TAATATATGTGGACTAAATTAATATTTTAAATCCATTAATATGTGTTTTATATGAATGGAAAGAAAATACTTAACTTATT
TAGTAGGGGGGACTTTTAAA

Downstream 100 bases:

>100_bases
AAAATATAAAACCTTGTAGTTTTAGAATTACAAGGTTTTTTGTTATTAAAAATTTTCTAGTCTATCAATAAGACTCTTTT
TATGGGTATTTTTGTATATA

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 547; Mature: 547

Protein sequence:

>547_residues
MLTEGKKGINKKLILLIITNVISFYIIFRLNIFMANNVDLAELTLIKDIKGINYIIGFISVFCCFLYYYLYEENYFFMFS
LIYLSIYSEFLIVDFLTKHINISALMHSNSSFVGFASIFRTLLLYLTIFNQNKVTKGICKNRFATVIFVLISNVLFILMD
LNIMKYYSHVINIDVLMIIKNIINLATYLLILEVCIKYFKEKEFNYFITFASLSVMFLSRILLVKSLYNDQKMMYILNRC
LLALGFFIIIISVFIEIITKSKENKELSYEVVNQKNEMYKLKEEEEMRSQFFANISHELRTPLNIIISSFQLLRMYNYNE
EEFLKYYNKYENTISQNCSRMLRLINNIIDVTKFDAGCFKMNFVNCEIISLVENITLSIAEYEKARKRNIIFDTDCEFLE
IKCDPENMERAILNLLSNAIKFTSDNGNIFVSIESQNNDECLSITIKDDGIGIPKDFRKSVFERFVQVDKSFRRNVEGSG
IGLSLVKYIVNSHNGEINLKDNEEKGCEFIINLPNVKIEDELDDIEFNLHKKDEIDSKILIELSDIK

Sequences:

>Translated_547_residues
MLTEGKKGINKKLILLIITNVISFYIIFRLNIFMANNVDLAELTLIKDIKGINYIIGFISVFCCFLYYYLYEENYFFMFS
LIYLSIYSEFLIVDFLTKHINISALMHSNSSFVGFASIFRTLLLYLTIFNQNKVTKGICKNRFATVIFVLISNVLFILMD
LNIMKYYSHVINIDVLMIIKNIINLATYLLILEVCIKYFKEKEFNYFITFASLSVMFLSRILLVKSLYNDQKMMYILNRC
LLALGFFIIIISVFIEIITKSKENKELSYEVVNQKNEMYKLKEEEEMRSQFFANISHELRTPLNIIISSFQLLRMYNYNE
EEFLKYYNKYENTISQNCSRMLRLINNIIDVTKFDAGCFKMNFVNCEIISLVENITLSIAEYEKARKRNIIFDTDCEFLE
IKCDPENMERAILNLLSNAIKFTSDNGNIFVSIESQNNDECLSITIKDDGIGIPKDFRKSVFERFVQVDKSFRRNVEGSG
IGLSLVKYIVNSHNGEINLKDNEEKGCEFIINLPNVKIEDELDDIEFNLHKKDEIDSKILIELSDIK
>Mature_547_residues
MLTEGKKGINKKLILLIITNVISFYIIFRLNIFMANNVDLAELTLIKDIKGINYIIGFISVFCCFLYYYLYEENYFFMFS
LIYLSIYSEFLIVDFLTKHINISALMHSNSSFVGFASIFRTLLLYLTIFNQNKVTKGICKNRFATVIFVLISNVLFILMD
LNIMKYYSHVINIDVLMIIKNIINLATYLLILEVCIKYFKEKEFNYFITFASLSVMFLSRILLVKSLYNDQKMMYILNRC
LLALGFFIIIISVFIEIITKSKENKELSYEVVNQKNEMYKLKEEEEMRSQFFANISHELRTPLNIIISSFQLLRMYNYNE
EEFLKYYNKYENTISQNCSRMLRLINNIIDVTKFDAGCFKMNFVNCEIISLVENITLSIAEYEKARKRNIIFDTDCEFLE
IKCDPENMERAILNLLSNAIKFTSDNGNIFVSIESQNNDECLSITIKDDGIGIPKDFRKSVFERFVQVDKSFRRNVEGSG
IGLSLVKYIVNSHNGEINLKDNEEKGCEFIINLPNVKIEDELDDIEFNLHKKDEIDSKILIELSDIK

Specific function: Member of the two-component regulatory system YycG/YycF involved in the regulation of the ftsAZ operon, the yocH and ykvT, cwlO, lytE, ydjM, yjeA, yoeB genes and the tagAB and tagDEF operons. Probably phosphorylates YycF [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789149, Length=261, Percent_Identity=31.0344827586207, Blast_Score=121, Evalue=1e-28,
Organism=Escherichia coli, GI1788713, Length=263, Percent_Identity=28.5171102661597, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI145693157, Length=272, Percent_Identity=28.3088235294118, Blast_Score=108, Evalue=1e-24,
Organism=Escherichia coli, GI1786600, Length=240, Percent_Identity=27.5, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=26.8595041322314, Blast_Score=102, Evalue=5e-23,
Organism=Escherichia coli, GI1786783, Length=232, Percent_Identity=28.0172413793103, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI87081816, Length=265, Percent_Identity=26.7924528301887, Blast_Score=93, Evalue=4e-20,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=26.8595041322314, Blast_Score=93, Evalue=5e-20,
Organism=Escherichia coli, GI1788393, Length=234, Percent_Identity=24.3589743589744, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=24.1666666666667, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1789808, Length=228, Percent_Identity=26.3157894736842, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1788549, Length=248, Percent_Identity=24.5967741935484, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790861, Length=315, Percent_Identity=24.7619047619048, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI87082128, Length=234, Percent_Identity=29.4871794871795, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=23.0125523012552, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1787894, Length=228, Percent_Identity=25, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1787374, Length=220, Percent_Identity=25, Blast_Score=67, Evalue=3e-12,
Organism=Escherichia coli, GI1788279, Length=245, Percent_Identity=28.5714285714286, Blast_Score=64, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 64092; Mature: 64092

Theoretical pI: Translated: 5.62; Mature: 5.62

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLTEGKKGINKKLILLIITNVISFYIIFRLNIFMANNVDLAELTLIKDIKGINYIIGFIS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHH
VFCCFLYYYLYEENYFFMFSLIYLSIYSEFLIVDFLTKHINISALMHSNSSFVGFASIFR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHH
TLLLYLTIFNQNKVTKGICKNRFATVIFVLISNVLFILMDLNIMKYYSHVINIDVLMIIK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIINLATYLLILEVCIKYFKEKEFNYFITFASLSVMFLSRILLVKSLYNDQKMMYILNRC
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LLALGFFIIIISVFIEIITKSKENKELSYEVVNQKNEMYKLKEEEEMRSQFFANISHELR
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHC
TPLNIIISSFQLLRMYNYNEEEFLKYYNKYENTISQNCSRMLRLINNIIDVTKFDAGCFK
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
MNFVNCEIISLVENITLSIAEYEKARKRNIIFDTDCEFLEIKCDPENMERAILNLLSNAI
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECHHHHHHHHHHHHHHHH
KFTSDNGNIFVSIESQNNDECLSITIKDDGIGIPKDFRKSVFERFVQVDKSFRRNVEGSG
EEECCCCEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
IGLSLVKYIVNSHNGEINLKDNEEKGCEFIINLPNVKIEDELDDIEFNLHKKDEIDSKIL
CHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCEEECCCCCCCEECCCCCCCCCCEEE
IELSDIK
EEEECCC
>Mature Secondary Structure
MLTEGKKGINKKLILLIITNVISFYIIFRLNIFMANNVDLAELTLIKDIKGINYIIGFIS
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEEECCCCHHHHHHHHHHHHHHHHHHHHH
VFCCFLYYYLYEENYFFMFSLIYLSIYSEFLIVDFLTKHINISALMHSNSSFVGFASIFR
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCEEEEEEECCCCCHHHHHHHH
TLLLYLTIFNQNKVTKGICKNRFATVIFVLISNVLFILMDLNIMKYYSHVINIDVLMIIK
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
NIINLATYLLILEVCIKYFKEKEFNYFITFASLSVMFLSRILLVKSLYNDQKMMYILNRC
HHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
LLALGFFIIIISVFIEIITKSKENKELSYEVVNQKNEMYKLKEEEEMRSQFFANISHELR
HHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHCCCHHHHHCCHHHHHHHHHHHHHHHHHC
TPLNIIISSFQLLRMYNYNEEEFLKYYNKYENTISQNCSRMLRLINNIIDVTKFDAGCFK
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEE
MNFVNCEIISLVENITLSIAEYEKARKRNIIFDTDCEFLEIKCDPENMERAILNLLSNAI
EEECCHHHHHHHHHHHHHHHHHHHHHHCCCEEECCCCEEEEEECHHHHHHHHHHHHHHHH
KFTSDNGNIFVSIESQNNDECLSITIKDDGIGIPKDFRKSVFERFVQVDKSFRRNVEGSG
EEECCCCEEEEEEECCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
IGLSLVKYIVNSHNGEINLKDNEEKGCEFIINLPNVKIEDELDDIEFNLHKKDEIDSKIL
CHHHHHHHHHHCCCCEEEECCCCCCCCEEEEECCCEEECCCCCCCEECCCCCCCCCCEEE
IELSDIK
EEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377; 9829949; 10878122; 11758928 [H]